PDB: 92212 resultsInfo pagesStatus searchChemie searchBIRD

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8EXM	Crystal structure of PTP1B D181A/Q262A phosphatase domain with a JAK3 activation loop phosphopeptide Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATE ION, Tyrosine-protein kinase JAK3 activation loop peptide, ... Authors: Morris, R, Kershaw, N.J, Babon, J.J. Deposit date: 2022-10-25 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.349 Å) Cite: Structure guided studies of the interaction between PTP1B and JAK. Commun Biol, 6, 2023
8EXN	Crystal structure of PTP1B D181A/Q262A phosphatase domain with TYK2 activation loop phosphopeptide Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Non-receptor tyrosine-protein kinase TYK2 activation loop peptide, PHOSPHATE ION, ... Authors: Morris, R, Kershaw, N.J, Babon, J.J. Deposit date: 2022-10-25 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.151 Å) Cite: Structure guided studies of the interaction between PTP1B and JAK. Commun Biol, 6, 2023
8F88	Crystal structure of PTP1B D181A/Q262A/C215A phosphatase domain with monophosphorylated JAK2 activation loop phosphopeptide Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein kinase JAK2, Tyrosine-protein phosphatase non-receptor type 1 Authors: Morris, R, Kershaw, N.J, Babon, J.J. Deposit date: 2022-11-21 Release date: 2023-07-05 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structure guided studies of the interaction between PTP1B and JAK. Commun Biol, 6, 2023
8EYA	Crystal structure of PTP1B D181A/Q262A/C215A phosphatase domain with a JAK2 activation loop phosphopeptide Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... Authors: Morris, R, Kershaw, N.J, Babon, J.J. Deposit date: 2022-10-26 Release date: 2023-07-05 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.099 Å) Cite: Structure guided studies of the interaction between PTP1B and JAK. Commun Biol, 6, 2023
8EYB	Crystal structure of PTP1B D181A/Q262A/C215A phosphatase domain with JAK2 activation loop phosphopeptide Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein kinase JAK2 activation loop phosphopeptide, Tyrosine-protein phosphatase non-receptor type 1 Authors: Morris, R, Kershaw, N.J, Babon, J.J. Deposit date: 2022-10-26 Release date: 2023-07-05 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.349 Å) Cite: Structure guided studies of the interaction between PTP1B and JAK. Commun Biol, 6, 2023
1X83	Y104F IPP isomerase reacted with (S)-bromohydrine of IPP Descriptor: (S)-4-BROMO-3-HYDROXY-3-METHYLBUTYL DIPHOSPHATE, Isopentenyl-diphosphate delta-isomerase, MAGNESIUM ION, ... Authors: Wouters, J, Oldfield, E. Deposit date: 2004-08-17 Release date: 2005-01-25 Last modified: 2021-10-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A Crystallographic Investigation of Phosphoantigen Binding to Isopentenyl Pyrophosphate/Dimethylallyl Pyrophosphate Isomerase J.Am.Chem.Soc., 127, 2005
8EXK	Crystal structure of PTP1B D181A/Q262A phosphatase domain with JAK2 activation loop phosphopeptide Descriptor: PHOSPHATE ION, Tyrosine-protein kinase JAK2 activation loop peptide, Tyrosine-protein phosphatase non-receptor type 1 Authors: Morris, R, Kershaw, N.J, Babon, J.J. Deposit date: 2022-10-25 Release date: 2023-07-05 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.096 Å) Cite: Structure guided studies of the interaction between PTP1B and JAK. Commun Biol, 6, 2023
7T0H	Crystal structure of S25-39 Fab Unliganded 2 Descriptor: BROMIDE ION, S25-39 Fab heavy chain, S25-39 Fab light chain Authors: Legg, M.S.G, Blackler, R.J, Evans, S.V. Deposit date: 2021-11-29 Release date: 2022-04-20 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Antigen binding by conformational selection in near-germline antibodies. J.Biol.Chem., 298, 2022
8EQA	Crystal structure of human anti-N1 neuraminidase 2H08 Fab Descriptor: 2H08 Fab heavy chain, 2H08 Fab light chain, ZINC ION Authors: Zhu, X, Wilson, I.A. Deposit date: 2022-10-07 Release date: 2023-08-09 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo. Immunity, 56, 2023
8EQC	Crystal structure of human anti-N1 neuraminidase 3H03 Fab Descriptor: 3H03 Fab heavy chain, 3H03 Fab light chain, PHOSPHATE ION Authors: Zhu, X, Wilson, I.A. Deposit date: 2022-10-07 Release date: 2023-08-09 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo. Immunity, 56, 2023
7T0J	Crystal structure of S25-2 Fab Unliganded 3 Descriptor: S25-2 Fab heavy chain, S25-2 Fab light chain Authors: Legg, M.S.G, Blackler, R.J, Evans, S.V. Deposit date: 2021-11-29 Release date: 2022-04-20 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Antigen binding by conformational selection in near-germline antibodies. J.Biol.Chem., 298, 2022
7T0I	Crystal structure of S25-39 Fab Unliganded 3 Descriptor: S25-39 Fab heavy chain, S25-39 Fab light chain Authors: Legg, M.S.G, Blackler, R.J, Evans, S.V. Deposit date: 2021-11-29 Release date: 2022-04-20 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Antigen binding by conformational selection in near-germline antibodies. J.Biol.Chem., 298, 2022
7T0G	Crystal structure of S25-39 Fab Unliganded 1 Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, S25-39 Fab heavy chain, S25-39 Fab light chain Authors: Legg, M.S.G, Blackler, R.J, Evans, S.V. Deposit date: 2021-11-29 Release date: 2022-04-20 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.53 Å) Cite: Antigen binding by conformational selection in near-germline antibodies. J.Biol.Chem., 298, 2022
7T0K	Crystal structure of S25-2 Fab Unliganded 4 Descriptor: IODIDE ION, S25-2 Fab heavy chain, S25-2 Fab light chain Authors: Legg, M.S.G, Blackler, R.J, Evans, S.V. Deposit date: 2021-11-29 Release date: 2022-04-20 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2 Å) Cite: Antigen binding by conformational selection in near-germline antibodies. J.Biol.Chem., 298, 2022
8F7T	Glycan-Base ConC Env Trimer Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env gp120, ... Authors: Olia, A.S, Kwong, P.D. Deposit date: 2022-11-20 Release date: 2023-09-27 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Soluble prefusion-closed HIV-envelope trimers with glycan-covered bases. Iscience, 26, 2023
7NMZ	Structure of 14-3-3 eta in complex with Nedd4-2(335-455) containing two 14-3-3 binding motifs Ser342 and Ser448 Descriptor: 14-3-3 protein eta, E3 ubiquitin-protein ligase NEDD4-like Authors: Pohl, P, Obsil, T, Obsilova, V. Deposit date: 2021-02-23 Release date: 2021-07-21 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.303 Å) Cite: 14-3-3-protein regulates Nedd4-2 by modulating interactions between HECT and WW domains. Commun Biol, 4, 2021
7YRV	Solution structures of a disulfide-directed multicyclic peptide with affinity for FGFR1 Descriptor: LF1 Authors: Fan, S.H, Wu, C.L. Deposit date: 2022-08-10 Release date: 2023-08-16 Method: SOLUTION NMR Cite: Disulfide-Directed Multicyclic Peptide Libraries for the Discovery of Pep-tide Ligands and Drugs To Be Published
7YRW	Solution structures of a disulfide-directed multicyclic peptide with affinity for HER2 Descriptor: LH2 Authors: Fan, S.H, Wu, C.L. Deposit date: 2022-08-10 Release date: 2023-08-16 Method: SOLUTION NMR Cite: Disulfide-Directed Multicyclic Peptide Libraries for the Discovery of Pep-tide Ligands and Drugs To Be Published
7YRX	Solution structures of a disulfide-directed multicyclic peptide with affinity for HER3 Descriptor: LH3 Authors: Fan, S.H, Wu, C.L. Deposit date: 2022-08-11 Release date: 2023-08-16 Method: SOLUTION NMR Cite: Disulfide-Directed Multicyclic Peptide Libraries for the Discovery of Pep-tide Ligands and Drugs To Be Published
7US1	Structure of parkin (R0RB) bound to two phospho-ubiquitin molecules Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase parkin, ... Authors: Fakih, R, Sauve, V, Gehring, K. Deposit date: 2022-04-22 Release date: 2022-06-22 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.484 Å) Cite: Structure of the second phosphoubiquitin-binding site in parkin. J.Biol.Chem., 298, 2022
2N8U	Solution Structure of the rNedd4 WW2 Domain by NMR Descriptor: E3 ubiquitin-protein ligase NEDD4 Authors: Spagnol, G, Kieken, F, Sorgen, P.L. Deposit date: 2015-10-27 Release date: 2016-02-24 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Structural Studies of the Nedd4 WW Domains and Their Selectivity for the Connexin43 (Cx43) Carboxyl Terminus. J. Biol. Chem., 291, 2016
4FAB	THREE-DIMENSIONAL STRUCTURE OF A FLUORESCEIN-FAB COMPLEX CRYSTALLIZED IN 2-METHYL-2,4-PENTANEDIOL Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, IGG2A-KAPPA 4-4-20 FAB (HEAVY CHAIN), ... Authors: Herron, J.N, He, X, Mason, M.L, Vossjunior, E.W, Edmundson, A.B. Deposit date: 1989-04-10 Release date: 1990-07-15 Last modified: 2017-09-27 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Three-dimensional structure of a fluorescein-Fab complex crystallized in 2-methyl-2,4-pentanediol. Proteins, 5, 1989
2AJ6	Crystal structure of a putative gnat family acetyltransferase (mw0638) from staphylococcus aureus subsp. aureus at 1.63 A resolution Descriptor: SULFATE ION, UNKNOWN LIGAND, hypothetical protein MW0638 Authors: Joint Center for Structural Genomics (JCSG) Deposit date: 2005-08-01 Release date: 2005-08-09 Last modified: 2023-01-25 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Crystal structure of hypothetical protein MW0638 from Staphylococcus aureus MW2 at 1.63 A resolution To be published
2K4D	E2-c-Cbl recognition is necessary but not sufficient for ubiquitination activity Descriptor: E3 ubiquitin-protein ligase CBL, ZINC ION Authors: Huang, A, De Jong, R.N, Wienk, H, Winkler, S.G, Timmers, H.T.M, Boelens, R. Deposit date: 2008-06-06 Release date: 2009-01-20 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: E2-c-Cbl recognition is necessary but not sufficient for ubiquitination activity J.Mol.Biol., 385, 2009
1L6M	Neutrophil Gelatinase-associated Lipocalin is a Novel Bacteriostatic Agent that Interferes with Siderophore-mediated Iron Acquisition Descriptor: 2,3-DIHYDROXY-BENZOIC ACID, 2-(2,3-DIHYDROXY-BENZOYLAMINO)-3-HYDROXY-PROPIONIC ACID, FE (III) ION, ... Authors: Goetz, D.H, Borregaard, N, Bluhm, M.E, Raymond, K.N, Strong, R.K. Deposit date: 2002-03-11 Release date: 2003-03-11 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.4 Å) Cite: The Neutrophil Lipocalin NGAL is a Bacteriostatic Agent that Interferes with Siderophore-mediated Iron Acquisition Mol.Cell, 10, 2002

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