PDB: 173 resultsInfo pagesStatus searchChemie searchBIRD

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2WL6	BIOSYNTHETIC THIOLASE FROM Z. RAMIGERA. THE N316H-H348N MUTANT. Descriptor: ACETYL-COA ACETYLTRANSFERASE Authors: Merilainen, G, Poikela, V, Kursula, P, Wierenga, R.K. Deposit date: 2009-06-22 Release date: 2009-11-03 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.98 Å) Cite: The Thiolase Reaction Mechanism: The Importance of Asn316 and His348 for Stabilizing the Enolate Intermediate of the Claisen Condensation. Biochemistry, 48, 2009
2WL5	BIOSYNTHETIC THIOLASE FROM Z. RAMIGERA. COMPLEX OF THE H348N MUTANT WITH COENZYME A. Descriptor: ACETYL-COA ACETYLTRANSFERASE, CHLORIDE ION, COENZYME A, ... Authors: Merilainen, G, Poikela, V, Kursula, P, Wierenga, R.K. Deposit date: 2009-06-22 Release date: 2009-11-03 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The Thiolase Reaction Mechanism: The Importance of Asn316 and His348 for Stabilizing the Enolate Intermediate of the Claisen Condensation. Biochemistry, 48, 2009
2WKV	BIOSYNTHETIC THIOLASE FROM Z. RAMIGERA. COMPLEX OF THE N316D MUTANT WITH COENZYME A. Descriptor: ACETYL-COA ACETYLTRANSFERASE, COENZYME A, SODIUM ION, ... Authors: Merilainen, G, Poikela, V, Kursula, P, Wierenga, R.K. Deposit date: 2009-06-18 Release date: 2009-11-03 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The Thiolase Reaction Mechanism: The Importance of Asn316 and His348 for Stabilizing the Enolate Intermediate of the Claisen Condensation. Biochemistry, 48, 2009
2WUA	Structure of the peroxisomal 3-ketoacyl-CoA thiolase from Sunflower Descriptor: ACETOACETYL COA THIOLASE Authors: Pye, V.E, Christensen, C.E, Dyer, J.H, Arent, S, Henriksen, A. Deposit date: 2009-10-01 Release date: 2010-05-12 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Peroxisomal Plant 3-Ketoacyl-Coa Thiolases Structure and Activity are Regulated by a Sensitive Redox Switch J.Biol.Chem., 285, 2010
2VU1	Biosynthetic thiolase from Z. ramigera. Complex of with O-pantheteine- 11-pivalate. Descriptor: ACETYL-COA ACETYLTRANSFERASE, PANTOTHENYL-AMINOETHANOL-11-PIVALIC ACID, SODIUM ION, ... Authors: Kursula, P, Schmitz, W, Wierenga, R.K. Deposit date: 2008-05-19 Release date: 2008-10-28 Last modified: 2019-07-24 Method: X-RAY DIFFRACTION (1.51 Å) Cite: The Sulfur Atoms of the Substrate Coa and the Catalytic Cysteine are Required for a Productive Mode of Substrate Binding in Bacterial Biosynthetic Thiolase, a Thioester-Dependent Enzyme. FEBS J., 275, 2008
2VTZ	Biosynthetic thiolase from Z. ramigera. Complex of the C89A mutant with coenzyme A. Descriptor: ACETYL-COA ACETYLTRANSFERASE, COENZYME A, SULFATE ION Authors: Kursula, P, Merilainen, G, Wierenga, R.K. Deposit date: 2008-05-19 Release date: 2008-10-28 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The Sulfur Atoms of the Substrate Coa and the Catalytic Cysteine are Required for a Productive Mode of Substrate Binding in Bacterial Biosynthetic Thiolase, a Thioester-Dependent Enzyme. FEBS J., 275, 2008
2WU9	Crystal structure of peroxisomal KAT2 from Arabidopsis thaliana Descriptor: 1,2-ETHANEDIOL, 3-KETOACYL-COA THIOLASE 2, PEROXISOMAL Authors: Pye, V.E, Christensen, C.E, Dyer, J.H, Arent, S, Henriksen, A. Deposit date: 2009-10-01 Release date: 2010-05-12 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Peroxisomal Plant 3-Ketoacyl-Coa Thiolases Structure and Activity are Regulated by a Sensitive Redox Switch J.Biol.Chem., 285, 2010
8JG2	Crystal structure of a biosynthetic thiolase from Megasphaera hexanoica soaked with hexanoyl-CoA Descriptor: ACETATE ION, Acetyl-CoA C-acetyltransferase, COENZYME A Authors: Kim, E.-J, Seo, H, Kim, K.-J. Deposit date: 2023-05-19 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (1.64 Å) Cite: Crystal structure of biosynthetic thiolase from Megasphaera hexanoica To Be Published
8JG3	Biosynthetic thiolase from Clostridium kluyveri Descriptor: Acetyl-CoA C-acetyltransferase Authors: Kim, E.-J, Seo, H, Kim, K.-J. Deposit date: 2023-05-19 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of biosynthetic thiolase from Clostridium kluyveri To Be Published
8OPW	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Caffeine (Fragment-B-51) Descriptor: 3-hydroxyacyl-CoA dehydrogenase, CAFFEINE, GLYCEROL, ... Authors: Dalwani, S, Wierenga, R.K, Venkatesan, R. Deposit date: 2023-04-10 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (2.52 Å) Cite: Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
8OQS	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-83 Descriptor: 3-hydroxyacyl-CoA dehydrogenase, 4-phenylbenzenesulfonic acid, GLYCEROL, ... Authors: Dalwani, S, Wierenga, R.K, Venkatesan, R. Deposit date: 2023-04-12 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (2.33 Å) Cite: Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
8OQM	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-10 Descriptor: 3-hydroxyacyl-CoA dehydrogenase, 6-azanyl-4-oxidanyl-naphthalene-2-sulfonic acid, GLYCEROL, ... Authors: Dalwani, S, Wierenga, R.K, Venkatesan, R. Deposit date: 2023-04-12 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
8OQR	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-80 Descriptor: 3-hydroxyacyl-CoA dehydrogenase, 4-cyanobenzenesulfonic acid, GLYCEROL, ... Authors: Dalwani, S, Wierenga, R.K, Venkatesan, R. Deposit date: 2023-04-12 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
8OPX	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Trehalose (Fragment-B-TRE) Descriptor: 3-hydroxyacyl-CoA dehydrogenase, Putative acyltransferase Rv0859, SULFATE ION, ... Authors: Dalwani, S, Wierenga, R.K, Venkatesan, R. Deposit date: 2023-04-10 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
8OQN	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-53 Descriptor: 1-benzyl-1H-pyrazole-4-carboxylic acid, 3-hydroxyacyl-CoA dehydrogenase, GLYCEROL, ... Authors: Dalwani, S, Wierenga, R.K, Venkatesan, R. Deposit date: 2023-04-12 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
8OQV	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-109 Descriptor: 3-hydroxyacyl-CoA dehydrogenase, 4-nitrobenzenesulfonic acid, GLYCEROL, ... Authors: Dalwani, S, Wierenga, R.K, Venkatesan, R. Deposit date: 2023-04-12 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (2.78 Å) Cite: Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
8OQO	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-49 Descriptor: 3-hydroxyacyl-CoA dehydrogenase, GLYCEROL, Putative acyltransferase Rv0859, ... Authors: Dalwani, S, Wierenga, R.K, Venkatesan, R. Deposit date: 2023-04-12 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
8OQP	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-76 Descriptor: 2-azanyl-5-sulfo-benzoic acid, 3-hydroxyacyl-CoA dehydrogenase, GLYCEROL, ... Authors: Dalwani, S, Wierenga, R.K, Venkatesan, R. Deposit date: 2023-04-12 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (2.18 Å) Cite: Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
8OPU	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Sulfamethoxazole (Fragment-B-E1) Descriptor: 3-hydroxyacyl-CoA dehydrogenase, GLYCEROL, Putative acyltransferase Rv0859, ... Authors: Dalwani, S, Wierenga, R.K, Venkatesan, R. Deposit date: 2023-04-10 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (3.04 Å) Cite: Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
8OPV	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Resveratrol (Fragment-B-H11) Descriptor: 3-hydroxyacyl-CoA dehydrogenase, GLYCEROL, Putative acyltransferase Rv0859, ... Authors: Dalwani, S, Wierenga, R.K, Venkatesan, R. Deposit date: 2023-04-10 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
8OQT	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-91 Descriptor: 3-hydroxyacyl-CoA dehydrogenase, 4-bromanylbenzenesulfonic acid, GLYCEROL, ... Authors: Dalwani, S, Wierenga, R.K, Venkatesan, R. Deposit date: 2023-04-12 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (2.62 Å) Cite: Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
8OQU	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-92 Descriptor: 3-hydroxyacyl-CoA dehydrogenase, 4-chloranylbenzenesulfonic acid, GLYCEROL, ... Authors: Dalwani, S, Wierenga, R.K, Venkatesan, R. Deposit date: 2023-04-12 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (2.89 Å) Cite: Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
8OQQ	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-79 Descriptor: 2-fluoranyl-5-sulfo-benzoic acid, 3-hydroxyacyl-CoA dehydrogenase, GLYCEROL, ... Authors: Dalwani, S, Wierenga, R.K, Venkatesan, R. Deposit date: 2023-04-12 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (2.59 Å) Cite: Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
8OPY	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-B-DNQ Descriptor: 3-hydroxyacyl-CoA dehydrogenase, 6,7-DINITROQUINOXALINE-2,3-DIONE, GLYCEROL, ... Authors: Dalwani, S, Wierenga, R.K, Venkatesan, R. Deposit date: 2023-04-10 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024
8OQL	Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-1 Descriptor: 3-hydroxyacyl-CoA dehydrogenase, FORMAMIDE, GLYCEROL, ... Authors: Dalwani, S, Wierenga, R.K, Venkatesan, R. Deposit date: 2023-04-12 Release date: 2024-01-24 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them Biorxiv, 2024

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