6WSG
 
 | | ClpX-ClpP complex bound to ssrA-tagged GFP, intermediate complex | | Descriptor: | ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, Green fluorescent protein, ... | | Authors: | Fei, X, Sauer, R.T. | | Deposit date: | 2020-04-30 | | Release date: | 2020-11-04 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.16 Å) | | Cite: | Structural basis of ClpXP recognition and unfolding of ssrA-tagged substrates.
Elife, 9, 2020
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6POD
 | | ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 2 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, ... | | Authors: | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | | Deposit date: | 2019-07-03 | | Release date: | 2020-03-11 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.05 Å) | | Cite: | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate.
Elife, 9, 2020
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6PO3
 | | ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 3 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, ... | | Authors: | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | | Deposit date: | 2019-07-03 | | Release date: | 2020-03-11 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.28 Å) | | Cite: | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate.
Elife, 9, 2020
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6PPE
 | | ClpP and ClpX IGF loop in ClpX-ClpP complex with D7 symmetry | | Descriptor: | ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit | | Authors: | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | | Deposit date: | 2019-07-06 | | Release date: | 2020-03-11 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.19 Å) | | Cite: | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate.
Elife, 9, 2020
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6POS
 | | ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 1 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, ... | | Authors: | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | | Deposit date: | 2019-07-05 | | Release date: | 2020-03-11 | | Method: | ELECTRON MICROSCOPY (4.12 Å) | | Cite: | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate.
Elife, 9, 2020
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6PO1
 | | ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 4 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, ... | | Authors: | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | | Deposit date: | 2019-07-03 | | Release date: | 2020-03-11 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate.
Elife, 9, 2020
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8E91
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8E7V
 | | Cryo-EM structure of substrate-free DNClpX.ClpP from singly capped particles | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ... | | Authors: | Ghanbarpour, A, Cohen, S, Davis, J.H, Sauer, R.T. | | Deposit date: | 2022-08-24 | | Release date: | 2023-11-08 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Cryo-EM structure of substrate-free DNClpX.ClpP
Nat Commun, 2023
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8E8Q
 | | Cryo-EM structure of substrate-free DNClpX.ClpP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ... | | Authors: | Ghanbarpour, A, Cohen, S, Davis, J.H, Sauer, R.T. | | Deposit date: | 2022-08-25 | | Release date: | 2023-11-08 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | Cryo-EM structure of substrate-free DNClpX.ClpP
Nat Commun, 2023
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8ET3
 | | Cryo-EM structure of a delivery complex containing the SspB adaptor, an ssrA-tagged substrate, and the AAA+ ClpXP protease | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, ... | | Authors: | Ghanbarpour, A, Fei, X, Davis, J.H, Sauer, R.T. | | Deposit date: | 2022-10-16 | | Release date: | 2023-01-25 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | The SspB adaptor drives structural changes in the AAA+ ClpXP protease during ssrA-tagged substrate delivery.
Proc.Natl.Acad.Sci.USA, 120, 2023
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6VFX
 | | ClpXP from Neisseria meningitidis - Conformation B | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ... | | Authors: | Ripstein, Z.A, Vahidi, S, Houry, W.A, Rubinstein, J.L, Kay, L.E. | | Deposit date: | 2020-01-06 | | Release date: | 2020-01-22 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery.
Elife, 9, 2020
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6VFS
 | | ClpXP from Neisseria meningitidis - Conformation A | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ... | | Authors: | Ripstein, Z.A, Vahidi, S, Houry, W.A, Rubinstein, J.L, Kay, L.E. | | Deposit date: | 2020-01-06 | | Release date: | 2020-01-22 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery.
Elife, 9, 2020
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6W20
 | | ClpAP Disengaged State bound to RepA-GFP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ... | | Authors: | Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R. | | Deposit date: | 2020-03-04 | | Release date: | 2020-05-06 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis.
Nat.Struct.Mol.Biol., 27, 2020
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6W21
 | | ClpAP Engaged2 State bound to RepA-GFP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ... | | Authors: | Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R. | | Deposit date: | 2020-03-04 | | Release date: | 2020-05-13 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis.
Nat.Struct.Mol.Biol., 27, 2020
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6W1Z
 | | ClpAP Engaged1 State bound to RepA-GFP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ... | | Authors: | Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R. | | Deposit date: | 2020-03-04 | | Release date: | 2020-05-06 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis.
Nat.Struct.Mol.Biol., 27, 2020
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7EKQ
 | | CrClpP-S2c | | Descriptor: | ATP-dependent Clp protease ATP-binding subunit CLPT4, chloroplastic, ATP-dependent Clp protease proteolytic subunit, ... | | Authors: | Wang, N, Wang, Y.F, Cong, Y, Liu, C.M. | | Deposit date: | 2021-04-06 | | Release date: | 2021-10-20 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | The cryo-EM structure of the chloroplast ClpP complex.
Nat.Plants, 7, 2021
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8XON
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8XOO
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6UQE
 | | ClpA/ClpP Disengaged State bound to RepA-GFP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease proteolytic subunit, ... | | Authors: | Lopez, K.L, Rizo, A.R, Southworth, D.R. | | Deposit date: | 2019-10-18 | | Release date: | 2020-04-22 | | Last modified: | 2022-03-16 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis.
Nat.Struct.Mol.Biol., 27, 2020
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6UQO
 | | ClpA/ClpP Engaged State bound to RepA-GFP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp endopeptidase proteolytic subunit ClpP, ATP-dependent Clp protease ATP-binding subunit ClpA, ... | | Authors: | Lopez, K.L, Rizo, A.N, Southworth, D.R. | | Deposit date: | 2019-10-21 | | Release date: | 2020-04-22 | | Last modified: | 2022-03-16 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis.
Nat.Struct.Mol.Biol., 27, 2020
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7UIY
 | | ClpAP complex bound to ClpS N-terminal extension, class IIIa | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ... | | Authors: | Kim, S, Fei, X, Sauer, R.T, Baker, T.A. | | Deposit date: | 2022-03-29 | | Release date: | 2022-10-26 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.22 Å) | | Cite: | AAA+ protease-adaptor structures reveal altered conformations and ring specialization.
Nat.Struct.Mol.Biol., 29, 2022
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7UIW
 | | ClpAP complex bound to ClpS N-terminal extension, class IIb | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ... | | Authors: | Kim, S, Fei, X, Sauer, R.T, Baker, T.A. | | Deposit date: | 2022-03-29 | | Release date: | 2022-11-09 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.33 Å) | | Cite: | AAA+ protease-adaptor structures reveal altered conformations and ring specialization.
Nat.Struct.Mol.Biol., 29, 2022
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7UJ0
 | | ClpAP complex bound to ClpS N-terminal extension, class IIIb | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ... | | Authors: | Kim, S, Fei, X, Sauer, R.T, Baker, T.A. | | Deposit date: | 2022-03-29 | | Release date: | 2022-11-09 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.26 Å) | | Cite: | AAA+ protease-adaptor structures reveal altered conformations and ring specialization.
Nat.Struct.Mol.Biol., 29, 2022
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7UIZ
 | | ClpAP complex bound to ClpS N-terminal extension, class IIc | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ... | | Authors: | Kim, S, Fei, X, Sauer, R.T, Baker, T.A. | | Deposit date: | 2022-03-29 | | Release date: | 2022-11-09 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.24 Å) | | Cite: | AAA+ protease-adaptor structures reveal altered conformations and ring specialization.
Nat.Struct.Mol.Biol., 29, 2022
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7UIX
 | | ClpAP complex bound to ClpS N-terminal extension, class I | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ... | | Authors: | Kim, S, Fei, X, Sauer, R.T, Baker, T.A. | | Deposit date: | 2022-03-29 | | Release date: | 2022-11-09 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.24 Å) | | Cite: | AAA+ protease-adaptor structures reveal altered conformations and ring specialization.
Nat.Struct.Mol.Biol., 29, 2022
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