Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3S17
DownloadVisualize
BU of 3s17 by Molmil
RNA Polymerase II Initiation Complex with a 9-nt RNA
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-14
Release date:2011-08-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
3S15
DownloadVisualize
BU of 3s15 by Molmil
RNA Polymerase II Initiation Complex with a 7-nt RNA
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-14
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
3S2H
DownloadVisualize
BU of 3s2h by Molmil
RNA Polymerase II Initiation Complex with a 6-nt RNA containing a 2[prime]-iodo ATP
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-16
Release date:2011-08-17
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
3S1M
DownloadVisualize
BU of 3s1m by Molmil
RNA Polymerase II Initiation Complex with a 5-nt RNA (variant 1)
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*GP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-15
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
6T0R
DownloadVisualize
BU of 6t0r by Molmil
Bat Influenza A polymerase product dissociation complex using 44-mer vRNA template with mutated oligo(U) sequence
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit, ...
Authors:Wandzik, J.M, Kouba, T, Cusack, S.
Deposit date:2019-10-03
Release date:2020-04-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase.
Cell, 181, 2020
6T0U
DownloadVisualize
BU of 6t0u by Molmil
Bat Influenza A polymerase product dissociation complex using 44-mer vRNA template with intact oligo(U) sequence
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit, ...
Authors:Wandzik, J.M, Kouba, T, Cusack, S.
Deposit date:2019-10-03
Release date:2020-04-15
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase.
Cell, 181, 2020
8RN2
DownloadVisualize
BU of 8rn2 by Molmil
Monomeric apo-influenza B polymerase, encapsidase conformation
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit
Authors:Arragain, B, Cusack, S.
Deposit date:2024-01-09
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase.
Nat Commun, 15, 2024
3RZD
DownloadVisualize
BU of 3rzd by Molmil
RNA Polymerase II Initiation Complex with a 5-nt RNA
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-11
Release date:2011-08-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
3RZO
DownloadVisualize
BU of 3rzo by Molmil
RNA Polymerase II Initiation Complex with a 4-nt RNA
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-12
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
3S1R
DownloadVisualize
BU of 3s1r by Molmil
RNA Polymerase II Initiation Complex with a 5-nt 3'-deoxy RNA soaked with GTP
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-16
Release date:2011-08-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
3S16
DownloadVisualize
BU of 3s16 by Molmil
RNA Polymerase II Initiation Complex with an 8-nt RNA
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-14
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.241 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
3S14
DownloadVisualize
BU of 3s14 by Molmil
RNA Polymerase II Initiation Complex with a 6-nt RNA
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-14
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
3S1N
DownloadVisualize
BU of 3s1n by Molmil
RNA Polymerase II Initiation Complex with a 5-nt RNA (variant 2)
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*GP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-15
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
3S2D
DownloadVisualize
BU of 3s2d by Molmil
RNA Polymerase II Initiation Complex with a 5-nt RNA containing a 5Br-U
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*AP*CP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-16
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
3S1Q
DownloadVisualize
BU of 3s1q by Molmil
RNA Polymerase II Initiation Complex with a 5-nt 3'-deoxy RNA soaked with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-16
Release date:2011-08-10
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
8JSL
DownloadVisualize
BU of 8jsl by Molmil
The structure of EBOV L-VP35-RNA complex
Descriptor: Polymerase cofactor VP35, RNA-directed RNA polymerase L, The leader sequence of EBOV, ...
Authors:Qi, P, Yi, S.
Deposit date:2023-06-20
Release date:2023-09-27
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Molecular mechanism of de novo replication by the Ebola virus polymerase.
Nature, 622, 2023
8JSM
DownloadVisualize
BU of 8jsm by Molmil
The structure of EBOV L-VP35-RNA complex (conformation 1)
Descriptor: Polymerase cofactor VP35, RNA-directed RNA polymerase L, The leader sequence of EBOV genome., ...
Authors:Qi, P, Yi, S.
Deposit date:2023-06-20
Release date:2023-09-27
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Molecular mechanism of de novo replication by the Ebola virus polymerase.
Nature, 622, 2023
8JSN
DownloadVisualize
BU of 8jsn by Molmil
The structure of EBOV L-VP35-RNA complex (conformation 2)
Descriptor: Polymerase cofactor VP35, RNA-directed RNA polymerase L, The leader sequence of EBOV genome, ...
Authors:Qi, P, Yi, S.
Deposit date:2023-06-20
Release date:2023-09-27
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular mechanism of de novo replication by the Ebola virus polymerase.
Nature, 622, 2023
7F4G
DownloadVisualize
BU of 7f4g by Molmil
Structure of RPAP2-bound RNA polymerase II
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Chen, X, Qi, Y, Wang, X, Li, J, Zhao, D, Xu, Y.
Deposit date:2021-06-18
Release date:2021-07-07
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (2.78 Å)
Cite:RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex.
Cell Rep, 39, 2022
2R7Z
DownloadVisualize
BU of 2r7z by Molmil
Cisplatin lesion containing RNA polymerase II elongation complex
Descriptor: 5'-D(*CP*AP*AP*GP*TP*AP*G)-3', 5'-D(*TP*AP*CP*TP*TP*GUP*CP*CP*CP*TP*CP*CP*TP*CP*AP*T)-3', 5'-R(*UP*UP*UP*GP*AP*GP*GP*AP*GP*G)-3', ...
Authors:Damsma, G.E, Alt, A, Brueckner, F, Carell, T, Cramer, P.
Deposit date:2007-09-10
Release date:2007-11-20
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Mechanism of transcriptional stalling at cisplatin-damaged DNA.
Nat.Struct.Mol.Biol., 14, 2007
2YU9
DownloadVisualize
BU of 2yu9 by Molmil
RNA polymerase II elongation complex in 150 mm MG+2 with UTP
Descriptor: 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ...
Authors:Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D.
Deposit date:2007-04-06
Release date:2007-04-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural Basis of Transcription: Role of the Trigger Loop in Substrate Specificity and Catalysis
Cell(Cambridge,Mass.), 127, 2006
5EPI
DownloadVisualize
BU of 5epi by Molmil
CRYSTAL STRUCTURE OF INFLUENZA B POLYMERASE WITH BOUND 5' CRNA EXHIBITS A NOVEL DOMAIN ARRANGEMENT
Descriptor: CRNA 5' END, Polymerase acidic protein, Polymerase basic protein 2, ...
Authors:Guilligay, D, Cusack, S.
Deposit date:2015-11-11
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of PB2 Domains.
Mol.Cell, 61, 2016
8Z8N
DownloadVisualize
BU of 8z8n by Molmil
Cryo-EM structure of Thogoto virus polymerase in transcription pre-initiation conformation 3
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*AP*GP*AP*AP*AP*UP*CP*AP*AP*GP*GP*CP*AP*GP*UP*U)-3'), ...
Authors:Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X.
Deposit date:2024-04-22
Release date:2024-05-29
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses.
Nat Commun, 15, 2024
8Z9Q
DownloadVisualize
BU of 8z9q by Molmil
Cryo-EM structure of Thogoto virus polymerase in a replication reception conformation
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-D(*(ATP))-R(P*GP*CP*AP*AP*AP*AP*AP*CP*A)-3'), ...
Authors:Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X.
Deposit date:2024-04-23
Release date:2024-05-29
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.33 Å)
Cite:Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses.
Nat Commun, 15, 2024
8Z8J
DownloadVisualize
BU of 8z8j by Molmil
Cryo-EM structure of Thogoto virus polymerase in transcription pre-initiation conformation 2
Descriptor: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*AP*GP*AP*AP*AP*UP*CP*AP*AP*GP*GP*CP*AP*GP*UP*U)-3'), ...
Authors:Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X.
Deposit date:2024-04-22
Release date:2024-05-29
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses.
Nat Commun, 15, 2024

227111

數據於2024-11-06公開中

PDB statisticsPDBj update infoContact PDBjnumon