1ENQ
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![BU of 1enq by Molmil](/molmil-images/mine/1enq) | CO-CRYSTALS OF DEMETALLIZED CONCANAVALIN A WITH ZINC HAVING A ZINC ION BOUND IN THE S1 SITE | Descriptor: | CONCANAVALIN A, ZINC ION | Authors: | Bouckaert, J, Loris, R, Poortmans, F, Wyns, L. | Deposit date: | 1996-03-20 | Release date: | 1996-08-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Sequential structural changes upon zinc and calcium binding to metal-free concanavalin A. J.Biol.Chem., 271, 1996
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4KR8
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1SFH
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![BU of 1sfh by Molmil](/molmil-images/mine/1sfh) | Reduced state of amicyanin mutant P94F | Descriptor: | Amicyanin, COPPER (I) ION, SODIUM ION | Authors: | Carrell, C.J, Sun, D, Jiang, S, Davidson, V.L, Mathews, F.S. | Deposit date: | 2004-02-19 | Release date: | 2004-07-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Structural Studies of Two Mutants of Amicyanin from Paracoccus denitrificans That Stabilize the Reduced State of the Copper. Biochemistry, 43, 2004
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1J8H
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![BU of 1j8h by Molmil](/molmil-images/mine/1j8h) | Crystal Structure of a Complex of a Human alpha/beta-T cell Receptor, Influenza HA Antigen Peptide, and MHC Class II Molecule, HLA-DR4 | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ HA1 PEPTIDE CHAIN, ... | Authors: | Hennecke, J, Wiley, D.C. | Deposit date: | 2001-05-21 | Release date: | 2002-03-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of a complex of the human alpha/beta T cell receptor (TCR) HA1.7, influenza hemagglutinin peptide, and major histocompatibility complex class II molecule, HLA-DR4 (DRA*0101 and DRB1*0401): insight into TCR cross-restriction and alloreactivity. J.Exp.Med., 195, 2002
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5HQ2
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![BU of 5hq2 by Molmil](/molmil-images/mine/5hq2) | Structural model of Set8 histone H4 Lys20 methyltransferase bound to nucleosome core particle | Descriptor: | DNA (149-MER), Guanine nucleotide exchange factor SRM1, Histone H2A, ... | Authors: | Tavarekere, G, McGinty, R.K, Tan, S. | Deposit date: | 2016-01-21 | Release date: | 2016-03-23 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | Multivalent Interactions by the Set8 Histone Methyltransferase With Its Nucleosome Substrate. J.Mol.Biol., 428, 2016
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4KPV
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![BU of 4kpv by Molmil](/molmil-images/mine/4kpv) | Crystal structure of the complex of ribosome inactivating protein from Momordica balsamina with Pyrimidine-2,4(1H,3H)-dione at 2.57 A resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, URACIL, rRNA N-glycosidase | Authors: | Yamini, S, Pandey, S, Kushwaha, G.S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2013-05-14 | Release date: | 2013-05-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Crystal structure of the complex of ribosome inactivating protein from Momordica balsamina with Pyrimidine-2,4(1H,3H)-dione at 2.57 A resolution To be Published
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1ESX
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![BU of 1esx by Molmil](/molmil-images/mine/1esx) | 1H, 15N AND 13C STRUCTURE OF THE HIV-1 REGULATORY PROTEIN VPR : COMPARISON WITH THE N-AND C-TERMINAL DOMAIN STRUCTURE, (1-51)VPR AND (52-96)VPR | Descriptor: | VPR PROTEIN | Authors: | Wecker, K, Morellet, N, Bouaziz, S, Roques, B. | Deposit date: | 2000-04-11 | Release date: | 2001-04-11 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | NMR structure of the HIV-1 regulatory protein Vpr in H2O/trifluoroethanol. Comparison with the Vpr N-terminal (1-51) and C-terminal (52-96) domains. Eur.J.Biochem., 269, 2002
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1ED5
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![BU of 1ed5 by Molmil](/molmil-images/mine/1ed5) | BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH NNA(H4B FREE) | Descriptor: | ACETATE ION, CACODYLIC ACID, GLYCEROL, ... | Authors: | Raman, C.S, Li, H, Martasek, P, Southan, G.J, Masters, B.S.S, Poulos, T.L. | Deposit date: | 2000-01-26 | Release date: | 2001-01-31 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of nitric oxide synthase bound to nitro indazole reveals a novel inactivation mechanism. Biochemistry, 40, 2001
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1IO8
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![BU of 1io8 by Molmil](/molmil-images/mine/1io8) | Thermophilic cytochrome P450 (CYP119) from sulfolobus solfataricus: High resolution structural origin of its thermostability and functional properties | Descriptor: | CYTOCHROME P450 CYP119, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Park, S.-Y, Yamane, K, Adachi, S, Shiro, Y, Sligar, S.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2001-02-08 | Release date: | 2001-03-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Thermophilic cytochrome P450 (CYP119) from Sulfolobus solfataricus: high resolution structure and functional properties J.Inorg.Biochem., 91, 2002
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1EUN
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1EV6
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![BU of 1ev6 by Molmil](/molmil-images/mine/1ev6) | Structure of the monoclinic form of the M-cresol/insulin R6 hexamer | Descriptor: | CHLORIDE ION, INSULIN, M-CRESOL, ... | Authors: | Smith, G.D, Ciszak, E, Magrum, L.A, Pangborn, W.A, Blessing, R.H. | Deposit date: | 2000-04-19 | Release date: | 2000-12-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | R6 Hexameric Insulin Complexed with m-Cresol or Resorcinol Biochem.Biophys.Res.Commun., 56, 2000
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1J4E
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![BU of 1j4e by Molmil](/molmil-images/mine/1j4e) | FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE COVALENTLY BOUND TO THE SUBSTRATE DIHYDROXYACETONE PHOSPHATE | Descriptor: | 1,3-DIHYDROXYACETONEPHOSPHATE, FRUCTOSE-BISPHOSPHATE ALDOLASE A | Authors: | Choi, K.H, Shi, J, Hopkins, C.E, Tolan, D.R, Allen, K.N. | Deposit date: | 2001-09-19 | Release date: | 2002-02-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Snapshots of catalysis: the structure of fructose-1,6-(bis)phosphate aldolase covalently bound to the substrate dihydroxyacetone phosphate. Biochemistry, 40, 2001
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4K9G
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![BU of 4k9g by Molmil](/molmil-images/mine/4k9g) | 1.55 A Crystal Structure of Macrophage Migration Inhibitory Factor bound to ISO-66 and a related compound | Descriptor: | (4R,6Z)-6-(3-fluoro-4-hydroxyphenyl)-4-hydroxy-6-iminohexan-2-one, 1-[(5S)-3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]propan-2-one, CHLORIDE ION, ... | Authors: | Crichlow, G.V, Al-Abed, Y, Lolis, E.J. | Deposit date: | 2013-04-19 | Release date: | 2014-09-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | ISO-66, a novel inhibitor of macrophage migration, shows efficacy in melanoma and colon cancer models. INT J ONCOL., 45, 2014
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4K9R
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![BU of 4k9r by Molmil](/molmil-images/mine/4k9r) | Spore photoproduct lyase Y98F mutant | Descriptor: | IRON/SULFUR CLUSTER, SULFATE ION, Spore photoproduct lyase, ... | Authors: | Yang, L, Nelson, R.S, Benjdia, A, Lin, G, Telser, J, Stoll, S, Schlichting, I, Li, L. | Deposit date: | 2013-04-20 | Release date: | 2013-05-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A radical transfer pathway in spore photoproduct lyase. Biochemistry, 52, 2013
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1EJT
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![BU of 1ejt by Molmil](/molmil-images/mine/1ejt) | CRYSTAL STRUCTURE OF THE H219Q VARIANT OF KLEBSIELLA AEROGENES UREASE | Descriptor: | NICKEL (II) ION, UREASE ALPHA SUBUNIT, UREASE BETA SUBUNIT, ... | Authors: | Pearson, M.A, Park, I.S, Schaller, R.A, Michel, L.O, Karplus, P.A, Hausinger, R.P. | Deposit date: | 2000-03-04 | Release date: | 2000-09-08 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Kinetic and structural characterization of urease active site variants. Biochemistry, 39, 2000
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1J8G
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![BU of 1j8g by Molmil](/molmil-images/mine/1j8g) | X-ray Analysis of a RNA Tetraplex r(uggggu)4 at Ultra-High Resolution | Descriptor: | 5'-R(*UP*GP*GP*GP*GP*U)-3', CALCIUM ION, SODIUM ION, ... | Authors: | Deng, J, Xiong, Y, Sundaralingam, M. | Deposit date: | 2001-05-21 | Release date: | 2001-11-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (0.61 Å) | Cite: | X-ray analysis of an RNA tetraplex (UGGGGU)(4) with divalent Sr(2+) ions at subatomic resolution (0.61 A). Proc.Natl.Acad.Sci.USA, 98, 2001
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1EAE
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4KAX
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![BU of 4kax by Molmil](/molmil-images/mine/4kax) | Crystal structure of the Grp1 PH domain in complex with Arf6-GTP | Descriptor: | ADP-ribosylation factor 6, CITRIC ACID, Cytohesin-3, ... | Authors: | Lambright, D.G, Malaby, A.W, van den Berg, B. | Deposit date: | 2013-04-23 | Release date: | 2013-08-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis for membrane recruitment and allosteric activation of cytohesin family Arf GTPase exchange factors. Proc.Natl.Acad.Sci.USA, 110, 2013
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1SHH
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![BU of 1shh by Molmil](/molmil-images/mine/1shh) | Slow form of Thrombin Bound with PPACK | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, thrombin | Authors: | Pineda, A.O, Carrell, C.J, Bush, L.A, Prasad, S, Caccia, S, Chen, Z.W, Mathews, F.S, Di Cera, E. | Deposit date: | 2004-02-25 | Release date: | 2004-06-08 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Molecular dissection of na+ binding to thrombin. J.Biol.Chem., 279, 2004
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1ESW
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![BU of 1esw by Molmil](/molmil-images/mine/1esw) | X-RAY STRUCTURE OF ACARBOSE BOUND TO AMYLOMALTASE FROM THERMUS AQUATICUS. IMPLICATIONS FOR THE SYNTHESIS OF LARGE CYCLIC GLUCANS | Descriptor: | 1,2-ETHANEDIOL, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, AMYLOMALTASE | Authors: | Przylas, I, Terada, Y, Fujii, K, Takaha, T, Saenger, W, Straeter, N. | Deposit date: | 2000-04-11 | Release date: | 2001-04-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | X-ray structure of acarbose bound to amylomaltase from Thermus aquaticus. Implications for the synthesis of large cyclic glucans. Eur.J.Biochem., 267, 2000
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1EUW
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![BU of 1euw by Molmil](/molmil-images/mine/1euw) | ATOMIC RESOLUTION STRUCTURE OF E. COLI DUTPASE | Descriptor: | DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE, ETHYL MERCURY ION, GLYCEROL | Authors: | Gonzalez, A, Cedergren, E, Larsson, G, Persson, R. | Deposit date: | 2000-04-17 | Release date: | 2000-05-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Atomic resolution structure of Escherichia coli dUTPase determined ab initio. Acta Crystallogr.,Sect.D, 57, 2001
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5HSA
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![BU of 5hsa by Molmil](/molmil-images/mine/5hsa) | Alcohol Oxidase AOX1 from Pichia Pastoris | Descriptor: | ARABINO-FLAVIN-ADENINE DINUCLEOTIDE, Alcohol oxidase 1, CALCIUM ION, ... | Authors: | Neumann, P, Ficner, R, Feussner, I, Koch, C. | Deposit date: | 2016-01-25 | Release date: | 2016-03-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal Structure of Alcohol Oxidase from Pichia pastoris. Plos One, 11, 2016
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1SN9
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1E7U
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![BU of 1e7u by Molmil](/molmil-images/mine/1e7u) | Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin and staurosporine | Descriptor: | (1S,6BR,9AS,11R,11BR)-9A,11B-DIMETHYL-1-[(METHYLOXY)METHYL]-3,6,9-TRIOXO-1,6,6B,7,8,9,9A,10,11,11B-DECAHYDRO-3H-FURO[4, 3,2-DE]INDENO[4,5-H][2]BENZOPYRAN-11-YL ACETATE, PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT | Authors: | Walker, E.H, Perisic, O, Ried, C, Stephens, L, Williams, R.L. | Deposit date: | 2000-09-08 | Release date: | 2000-11-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Determinations of Phosphoinositide 3-Kinase Inhibition by Wortmannin, Ly294002, Quercetin, Myricetin and Staurosporine Mol.Cell, 6, 2000
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1SNG
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![BU of 1sng by Molmil](/molmil-images/mine/1sng) | Structure of a Thermophilic Serpin in the Native State | Descriptor: | COG4826: Serine protease inhibitor, SULFATE ION | Authors: | Fulton, K.F, Buckle, A.M, Cabrita, L.D, Irving, J.A, Butcher, R.E, Smith, I, Reeve, S, Lesk, A.M, Bottomley, S.P, Rossjohn, J, Whisstock, J.C. | Deposit date: | 2004-03-10 | Release date: | 2004-12-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | The high resolution crystal structure of a native thermostable serpin reveals the complex mechanism underpinning the stressed to relaxed transition. J.Biol.Chem., 280, 2005
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