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8RED
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BU of 8red by Molmil
Cryo-EM structure of bacterial RNA polymerase-sigma54 initial transcribing complex - 8nt complex
Descriptor: DNA (46-MER), DNA (51-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Gao, F, Zhang, X.
Deposit date:2023-12-10
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of sigma 54 displacement and promoter escape in bacterial transcription.
Proc.Natl.Acad.Sci.USA, 121, 2024
5V4R
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BU of 5v4r by Molmil
Crystal structure of LARP1-unique domain DM15 bound to m7GTP
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, La-related protein 1
Authors:Berman, A.J, Lahr, R.M.
Deposit date:2017-03-10
Release date:2017-04-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs.
Elife, 6, 2017
7LMB
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BU of 7lmb by Molmil
Tetrahymena telomerase T5D5 structure at 3.8 Angstrom
Descriptor: Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ...
Authors:He, Y, Wang, Y, Liu, B, Helmling, C, Susac, L, Cheng, R, Zhou, Z.H, Feigon, J.
Deposit date:2021-02-05
Release date:2021-05-12
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structures of telomerase at several steps of telomere repeat synthesis.
Nature, 593, 2021
7OZS
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BU of 7ozs by Molmil
Structure of the hexameric 5S RNP from C. thermophilum
Descriptor: 5S rRNA, 60S ribosomal protein l5-like protein, Putative ribosomal protein, ...
Authors:Castillo, N, Thoms, M, Flemming, D, Hammaren, H.M, Buschauer, R, Ameismeier, M, Bassler, J, Beck, M, Beckmann, R, Hurt, E.
Deposit date:2021-06-28
Release date:2022-10-12
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of nascent 5S RNPs at the crossroad between ribosome assembly and MDM2-p53 pathways.
Nat.Struct.Mol.Biol., 2023
5V87
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BU of 5v87 by Molmil
Crystal structure of LARP1-unique domain DM15 bound to m7GpppC
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, La-related protein 1, [[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-9-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [[(2~{R},3~{S},4~{R},5~{R})-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] hydrogen phosphate
Authors:Berman, A.J, Lahr, R.M.
Deposit date:2017-03-21
Release date:2017-04-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.692 Å)
Cite:La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs.
Elife, 6, 2017
5TCU
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BU of 5tcu by Molmil
Methicillin sensitive Staphylococcus aureus 70S ribosome
Descriptor: 16S RRNA, 23S RRNA, 30S ribosomal protein S10, ...
Authors:Eyal, Z, Ahmed, T, Belousoff, N, Mishra, S, Matzov, D, Bashan, A, Zimmerman, E, Lithgow, T, Bhushan, S, Yonath, A.
Deposit date:2016-09-15
Release date:2017-05-24
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Basis for Linezolid Binding Site Rearrangement in the Staphylococcus aureus Ribosome.
MBio, 8, 2017
7LMA
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BU of 7lma by Molmil
Tetrahymena telomerase T3D2 structure at 3.3 Angstrom
Descriptor: Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ...
Authors:He, Y, Wang, Y, Liu, B, Helmling, C, Susac, L, Cheng, R, Zhou, Z.H, Feigon, J.
Deposit date:2021-02-05
Release date:2021-05-12
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structures of telomerase at several steps of telomere repeat synthesis.
Nature, 593, 2021
6LAU
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BU of 6lau by Molmil
the wildtype SAM-VI riboswitch bound to SAH
Descriptor: CESIUM ION, GUANOSINE-5'-TRIPHOSPHATE, RNA (54-MER), ...
Authors:Ren, A, Sun, A.
Deposit date:2019-11-13
Release date:2020-01-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.109 Å)
Cite:SAM-VI riboswitch structure and signature for ligand discrimination.
Nat Commun, 10, 2019
2DFE
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BU of 2dfe by Molmil
Crystal structure of Tk-RNase HII(1-200)-C
Descriptor: Ribonuclease HII
Authors:Katagiri, Y, Takano, K, Chon, H, Matsumura, H, Koga, Y, Kanaya, S.
Deposit date:2006-03-01
Release date:2007-03-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Conformational contagion in a protein: Structural properties of a chameleon sequence
Proteins, 68, 2007
2DFF
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BU of 2dff by Molmil
Crystal structure of Tk-RNase HII(1-204)-C
Descriptor: Ribonuclease HII
Authors:Katagiri, Y, Takano, K, Chon, H, Matsumura, H, Koga, Y, Kanaya, S.
Deposit date:2006-03-01
Release date:2007-03-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Conformational contagion in a protein: Structural properties of a chameleon sequence
Proteins, 68, 2007
7Z05
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BU of 7z05 by Molmil
White Bream virus N7-Methyltransferase
Descriptor: DI(HYDROXYETHYL)ETHER, Non-structural protein 1, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Shannon, A, Gauffre, P, Canard, B, Ferron, F.
Deposit date:2022-02-22
Release date:2022-09-28
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:A second type of N7-guanine RNA cap methyltransferase in an unusual locus of a large RNA virus genome.
Nucleic Acids Res., 50, 2022
2DFH
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BU of 2dfh by Molmil
Crystal structure of Tk-RNase HII(1-212)-C
Descriptor: Ribonuclease HII
Authors:Katagiri, Y, Takano, K, Chon, H, Matsumura, H, Koga, Y, Kanaya, S.
Deposit date:2006-03-01
Release date:2007-03-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Conformational contagion in a protein: Structural properties of a chameleon sequence
Proteins, 68, 2007
4PPH
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BU of 4pph by Molmil
Crystal structure of conglutin gamma, a unique basic 7S globulin from lupine seeds
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Czubinski, J, Barciszewski, J, Gilski, M, Lampart-Szczapa, E, Jaskolski, M.
Deposit date:2014-02-27
Release date:2015-02-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.009 Å)
Cite:Structure of gamma-conglutin: insight into the quaternary structure of 7S basic globulins from legumes.
Acta Crystallogr.,Sect.D, 71, 2015
1ETU
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BU of 1etu by Molmil
STRUCTURAL DETAILS OF THE BINDING OF GUANOSINE DIPHOSPHATE TO ELONGATION FACTOR TU FROM E. COLI AS STUDIED BY X-RAY CRYSTALLOGRAPHY
Descriptor: ELONGATION FACTOR TU, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Clark, B.F.C, Lacour, T.F.M, Kjeldgaard, M, Morikawa, K, Nyborg, J, Rubin, R, Thirup, S.
Deposit date:1988-01-15
Release date:1988-07-16
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural details of the binding of guanosine diphosphate to elongation factor Tu from E. coli as studied by X-ray crystallography.
EMBO J., 4, 1985
7N0U
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BU of 7n0u by Molmil
Complex of recombinant Bet v 1 with Fab fragment of REGN5713
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, REGN5713 Fab fragment heavy chain, REGN5713 Fab fragment light chain, ...
Authors:Franklin, M.C, Romero Hernandez, A.
Deposit date:2021-05-26
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Targeting immunodominant Bet v 1 epitopes with monoclonal antibodies prevents the birch allergic response.
J.Allergy Clin.Immunol., 149, 2022
7N0V
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BU of 7n0v by Molmil
Complex of recombinant Bet v 1 with Fab fragment of REGN5715
Descriptor: Major pollen allergen Bet v 1-A, REGN5715 Fab heavy chain, REGN5715 Fab light chain
Authors:Franklin, M.C, Romero Hernandez, A.
Deposit date:2021-05-26
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.71 Å)
Cite:Targeting immunodominant Bet v 1 epitopes with monoclonal antibodies prevents the birch allergic response.
J.Allergy Clin.Immunol., 149, 2022
7T7H
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BU of 7t7h by Molmil
Crystal structure of Vaccinia Virus decapping enzyme D9 in complex with inhibitor CP100356
Descriptor: 4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxyquinazolin-2-amine, DNA repair NTP-phosphohydrolase, SODIUM ION
Authors:Peters, J.K, Gross, J.D.
Deposit date:2021-12-15
Release date:2022-06-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.78000259 Å)
Cite:Fluorescence-Based Activity Screening Assay Reveals Small Molecule Inhibitors of Vaccinia Virus mRNA Decapping Enzyme D9.
Acs Chem.Biol., 17, 2022
5C3I
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BU of 5c3i by Molmil
Crystal structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2
Descriptor: DNA replication licensing factor MCM2,MCM2, Histone H3.1, Histone H4, ...
Authors:Wang, H, Wang, M, Yang, N, Xu, R.M.
Deposit date:2015-06-17
Release date:2015-07-29
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of the quaternary complex of histone H3-H4 heterodimer with chaperone ASF1 and the replicative helicase subunit MCM2
Protein Cell, 6, 2015
5OSG
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BU of 5osg by Molmil
Structure of KSRP in context of Leishmania donovani 80S
Descriptor: 18S rRNA, 40S ribosomal protein S6, RNA binding protein, ...
Authors:Brito Querido, J, Mancera-Martinez, E, Vicens, Q, Bochler, A, Chicher, J, Simonetti, A, Hashem, Y.
Deposit date:2017-08-17
Release date:2017-11-15
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The cryo-EM Structure of a Novel 40S Kinetoplastid-Specific Ribosomal Protein.
Structure, 25, 2017
1FOQ
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BU of 1foq by Molmil
PENTAMERIC MODEL OF THE BACTERIOPHAGE PHI29 PROHEAD RNA
Descriptor: BACTERIOPHAGE PHI29 PROHEAD RNA
Authors:Simpson, A.A, Tao, Y, Leiman, P.G, Badasso, M.O, He, Y, Jardine, P.J, Olson, N.H, Morais, M.C, Grimes, S, Anderson, D.L, Baker, T.S, Rossmann, M.G.
Deposit date:2000-08-28
Release date:2000-12-22
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Structure of the bacteriophage phi29 DNA packaging motor.
Nature, 408, 2000
1NXZ
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BU of 1nxz by Molmil
X-Ray Crystal Structure of Protein yggj_haein of Haemophilus influenzae. Northeast Structural Genomics Consortium Target IR73.
Descriptor: Hypothetical protein HI0303
Authors:Forouhar, F, Shen, J, Xiao, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2003-02-11
Release date:2003-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Functional assignment based on structural analysis: crystal structure of the yggJ protein (HI0303) of Haemophilus influenzae reveals an RNA methyltransferase with a deep trefoil knot.
Proteins, 53, 2003
1B3S
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BU of 1b3s by Molmil
STRUCTURAL RESPONSE TO MUTATION AT A PROTEIN-PROTEIN INTERFACE
Descriptor: PROTEIN (BARNASE), PROTEIN (BARSTAR)
Authors:Vaughan, C.K, Buckle, A.M, Fersht, A.R.
Deposit date:1998-12-01
Release date:1998-12-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structural response to mutation at a protein-protein interface.
J.Mol.Biol., 286, 1999
1B2S
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BU of 1b2s by Molmil
STRUCTURAL RESPONSE TO MUTATION AT A PROTEIN-PROTEIN INTERFACE
Descriptor: PROTEIN (BARNASE), PROTEIN (BARSTAR), SULFATE ION
Authors:Vaughan, C.K, Buckle, A.M, Fersht, A.R.
Deposit date:1998-11-30
Release date:1998-12-08
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Structural response to mutation at a protein-protein interface.
J.Mol.Biol., 286, 1999
429D
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BU of 429d by Molmil
CRYSTAL STRUCTURE OF A LEADZYME; METAL BINDING AND IMPLICATIONS FOR CATALYSIS
Descriptor: MAGNESIUM ION, RNA (5'-R(*CP*GP*GP*AP*CP*CP*GP*AP*GP*CP*CP*AP*G)-3'), RNA (5'-R(*GP*CP*UP*GP*GP*GP*AP*GP*UP*CP*C)-3')
Authors:Wedekind, J.E, McKay, D.B.
Deposit date:1998-09-29
Release date:1999-03-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of a lead-dependent ribozyme revealing metal binding sites relevant to catalysis.
Nat.Struct.Biol., 6, 1999
7ORN
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BU of 7orn by Molmil
La Crosse virus polymerase at replication initiation stage
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, La Crosse virus polymerase, MAGNESIUM ION, ...
Authors:Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H.
Deposit date:2021-06-06
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription.
Nat Commun, 13, 2022

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數據於2024-07-17公開中

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