2O93
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2o93 by Molmil](/molmil-images/mine/2o93) | |
2OAC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2oac by Molmil](/molmil-images/mine/2oac) | |
2OBF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2obf by Molmil](/molmil-images/mine/2obf) | Structure of K57A hPNMT with inhibitor 3-Hydroxymethyl-7-(N-4-chlorophenylaminosulfonyl)-THIQ and AdoHcy (SAH) | Descriptor: | (3R)-N-(4-CHLOROPHENYL)-3-(HYDROXYMETHYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Drinkwater, N, Martin, J.L. | Deposit date: | 2006-12-19 | Release date: | 2007-10-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Enzyme Adaptation to Inhibitor Binding: A Cryptic Binding Site in Phenylethanolamine N-Methyltransferase J.Med.Chem., 50, 2007
|
|
3GZE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gze by Molmil](/molmil-images/mine/3gze) | |
3T43
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3t43 by Molmil](/molmil-images/mine/3t43) | |
2OAM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2oam by Molmil](/molmil-images/mine/2oam) | |
3T2A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3t2a by Molmil](/molmil-images/mine/3t2a) | TMAO-grown cubic insulin (porcine) | Descriptor: | Insulin A chain, Insulin B chain, trimethylamine oxide | Authors: | Cahn, J, Venkat, M, Marshall, H, Juers, D. | Deposit date: | 2011-07-22 | Release date: | 2011-12-28 | Last modified: | 2012-01-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography. Acta Crystallogr.,Sect.D, 68, 2012
|
|
3H91
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3h91 by Molmil](/molmil-images/mine/3h91) | Crystal structure of the complex of human chromobox homolog 2 (CBX2) and H3K27 peptide | Descriptor: | Chromobox protein homolog 2, H3K27 peptide | Authors: | Amaya, M.F, Ravichandran, M, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-04-29 | Release date: | 2009-08-18 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Recognition and specificity determinants of the human cbx chromodomains. J.Biol.Chem., 286, 2011
|
|
2OE7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2oe7 by Molmil](/molmil-images/mine/2oe7) | High-Pressure T4 Lysozyme | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme | Authors: | Collins, M.D, Quillin, M.L, Matthews, B.W, Gruner, S.M. | Deposit date: | 2006-12-28 | Release date: | 2007-01-30 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Rigidity of a Large Cavity-containing Protein Revealed by High-pressure Crystallography. J.Mol.Biol., 367, 2007
|
|
3H97
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3h97 by Molmil](/molmil-images/mine/3h97) | Structure of a mutant methionyl-tRNA synthetase with modified specificity | Descriptor: | CITRIC ACID, Methionyl-tRNA synthetase, ZINC ION | Authors: | Schmitt, E, Tanrikulu, I.C, Yoo, T.H, Panvert, M, Tirrell, D.A, Mechulam, Y. | Deposit date: | 2009-04-30 | Release date: | 2009-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Switching from an induced-fit to a lock-and-key mechanism in an aminoacyl-tRNA synthetase with modified specificity. J.Mol.Biol., 394, 2009
|
|
3HAN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3han by Molmil](/molmil-images/mine/3han) | |
3T8O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3t8o by Molmil](/molmil-images/mine/3t8o) | Rhodopsin kinase (GRK1) L166K mutant at 2.5A resolution | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | Authors: | Tesmer, J.J.G, Singh, P, Nance, M.R. | Deposit date: | 2011-08-01 | Release date: | 2012-06-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of a monomeric variant of rhodopsin kinase at 2.5 A resolution. Acta Crystallogr.,Sect.F, 68, 2012
|
|
2OG0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2og0 by Molmil](/molmil-images/mine/2og0) | Crystal Structure of the Lambda Xis-DNA complex | Descriptor: | 5'-D(*AP*AP*AP*CP*AP*GP*AP*CP*TP*AP*CP*AP*TP*AP*AP*TP*AP*C)-3', 5'-D(*GP*TP*AP*TP*TP*AP*TP*GP*TP*AP*GP*TP*CP*TP*GP*TP*TP*T)-3', Excisionase | Authors: | Papagiannis, C.V, Sam, M.D, Abbani, M.A, Cascio, D, Yoo, D, Clubb, R.T, Johnson, R.C. | Deposit date: | 2007-01-04 | Release date: | 2007-03-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Fis targets assembly of the xis nucleoprotein filament to promote excisive recombination by phage lambda. J.Mol.Biol., 367, 2007
|
|
3T6N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3t6n by Molmil](/molmil-images/mine/3t6n) | |
3HBV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hbv by Molmil](/molmil-images/mine/3hbv) | PrtC methionine mutants: M226A in-house | Descriptor: | CALCIUM ION, CHLORIDE ION, Secreted protease C, ... | Authors: | Oberholzer, A.E, Bumann, M, Hege, T, Russo, S, Baumann, U. | Deposit date: | 2009-05-05 | Release date: | 2009-06-30 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Metzincin's canonical methionine is responsible for the structural integrity of the zinc-binding site Biol.Chem., 390, 2009
|
|
3H99
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3h99 by Molmil](/molmil-images/mine/3h99) | Structure of a mutant methionyl-tRNA synthetase with modified specificity complexed with methionine | Descriptor: | CITRIC ACID, METHIONINE, Methionyl-tRNA synthetase, ... | Authors: | Schmitt, E, Tanrikulu, I.C, Yoo, T.H, Panvert, M, Tirrell, D.A, Mechulam, Y. | Deposit date: | 2009-04-30 | Release date: | 2009-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Switching from an induced-fit to a lock-and-key mechanism in an aminoacyl-tRNA synthetase with modified specificity. J.Mol.Biol., 394, 2009
|
|
2OHA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2oha by Molmil](/molmil-images/mine/2oha) | Myoglobin cavity mutant F138W | Descriptor: | Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | Authors: | Phillips Jr, G.N, Soman, J, Olson, J.S. | Deposit date: | 2007-01-09 | Release date: | 2007-01-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Ligand pathways in myoglobin: A review of trp cavity mutations. Iubmb Life, 59, 2007
|
|
3HCX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hcx by Molmil](/molmil-images/mine/3hcx) | Crystal structure of E. coli HPPK(N10A) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, CHLORIDE ION | Authors: | Blaszczyk, J, Li, Y, Yan, H, Ji, X. | Deposit date: | 2009-05-06 | Release date: | 2010-05-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Role of loop coupling in enzymatic catalysis and conformational dynamics To be Published
|
|
3T8B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3t8b by Molmil](/molmil-images/mine/3t8b) | Crystal structure of Mycobacterium tuberculosis MenB with altered hexameric assembly | Descriptor: | 1,4-Dihydroxy-2-naphthoyl-CoA synthase, GLYCEROL | Authors: | Li, H.-J, Li, X, Liu, N, Zhang, H, Truglio, J, Mishra, S, Kisker, C, Garcia-Diaz, M, Tonge, P. | Deposit date: | 2011-08-01 | Release date: | 2011-08-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.649 Å) | Cite: | Mechanism of the Intramolecular Claisen Condensation Reaction Catalyzed by MenB, a Crotonase Superfamily Member. Biochemistry, 50, 2011
|
|
2OJL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ojl by Molmil](/molmil-images/mine/2ojl) | Crystal structure of Q7WAF1_BORPA from Bordetella parapertussis. Northeast Structural Genomics target BpR68. | Descriptor: | Hypothetical protein | Authors: | Benach, J, Neely, H, Seetharaman, J, Wang, H, Fang, Y, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-01-12 | Release date: | 2007-01-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of Q7WAF1_BORPA from Bordetella parapertussis To be Published
|
|
3SQ6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3sq6 by Molmil](/molmil-images/mine/3sq6) | Crystal Structures of the Ligand Binding Domain of a Pentameric Alpha7 Nicotinic Receptor Chimera with its Agonist Epibatidine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EPIBATIDINE, ... | Authors: | Li, S.-X, Huang, S, Bren, N, Noridomi, K, Dellisanti, C, Sine, S, Chen, L. | Deposit date: | 2011-07-05 | Release date: | 2011-09-28 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Ligand-binding domain of an alpha 7-nicotinic receptor chimera and its complex with agonist. Nat.Neurosci., 14, 2011
|
|
3SR6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3sr6 by Molmil](/molmil-images/mine/3sr6) | Crystal Structure of Reduced Bovine Xanthine Oxidase in Complex with Arsenite | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHONIC ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER, ... | Authors: | Cao, H, Hille, R. | Deposit date: | 2011-07-07 | Release date: | 2011-07-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | X-ray Crystal Structure of Arsenite-Inhibited Xanthine Oxidase: Mu-Sulfido,Mu-Oxo Double Bridge between Molybdenum and Arsenic in the Active Site. J.Am.Chem.Soc., 133, 2011
|
|
3GO7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3go7 by Molmil](/molmil-images/mine/3go7) | Crystal Structure of M. tuberculosis ribokinase (Rv2436) in complex with ribose | Descriptor: | MAGNESIUM ION, RIBOKINASE RBSK, alpha-D-ribofuranose | Authors: | Masters, E.I, Sun, Y, Wang, Y, Parker, W.B, Li, R. | Deposit date: | 2009-03-18 | Release date: | 2010-03-31 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure and biochemical characterization of M.tuberculosis ribokinase (Rv2436) To be Published
|
|
3SSC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ssc by Molmil](/molmil-images/mine/3ssc) | DNA binding domain of restriction endonuclease bound to DNA | Descriptor: | 5-methylcytosine-specific restriction enzyme B, DNA (5'-D(*AP*GP*CP*TP*AP*(5CM)P*CP*GP*GP*TP*CP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*GP*AP*(5CM)P*CP*GP*GP*TP*AP*GP*C)-3') | Authors: | Sukackaite, R, Grazulis, S, Siksnys, V. | Deposit date: | 2011-07-08 | Release date: | 2012-05-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The recognition domain of the methyl-specific endonuclease McrBC flips out 5-methylcytosine. Nucleic Acids Res., 40, 2012
|
|
3GOI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3goi by Molmil](/molmil-images/mine/3goi) | Human glucokinase in complex with a synthetic activator | Descriptor: | 2-(methylamino)-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide, Glucokinase, alpha-D-glucopyranose | Authors: | Kamata, K, Mitsuya, M. | Deposit date: | 2009-03-19 | Release date: | 2009-04-28 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Discovery of novel 3,6-disubstituted 2-pyridinecarboxamide derivatives as GK activators Bioorg.Med.Chem.Lett., 19, 2009
|
|