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8DAU
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BU of 8dau by Molmil
Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to two folded ubiquitin moieties and one unfolded ubiquitin in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 1 (uA)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ...
Authors:Lee, H.G, Lima, C.D.
Deposit date:2022-06-14
Release date:2022-11-30
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:SUMO enhances unfolding of SUMO-polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DAT
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BU of 8dat by Molmil
Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to three ubiquitin moieties in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 1 (intB)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ...
Authors:Lee, H.G, Lima, C.D.
Deposit date:2022-06-14
Release date:2022-11-30
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:SUMO enhances unfolding of SUMO-polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DAS
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BU of 8das by Molmil
Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to two ubiquitin moieties in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 1 (intA)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ...
Authors:Lee, H.G, Lima, C.D.
Deposit date:2022-06-14
Release date:2022-11-30
Last modified:2023-01-11
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:SUMO enhances unfolding of SUMO-polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DAV
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BU of 8dav by Molmil
Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to two ubiquitin moieties and one unfolded ubiquitin in presence of SUMO-ubiquitin(K48polyUb)-mEOS and ATP, state 2 (uC)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 48, ...
Authors:Lee, H.G, Lima, C.D.
Deposit date:2022-06-14
Release date:2022-11-30
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:SUMO enhances unfolding of SUMO-polyubiquitin-modified substrates by the Ufd1/Npl4/Cdc48 complex.
Proc.Natl.Acad.Sci.USA, 120, 2023
8CQW
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BU of 8cqw by Molmil
Crystal structure of the Candida albicans 80S ribosome in complex with Hygromycin B
Descriptor: 18S, 25S, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ...
Authors:Kolosova, O, Zgadzay, Y, Yusupov, M.
Deposit date:2023-03-07
Release date:2024-09-18
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
To Be Published
8CRE
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BU of 8cre by Molmil
Crystal structure of the Candida albicans 80S ribosome in complex with geneticin G418
Descriptor: 18S, 25S, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ...
Authors:Kolosova, O, Zgadzay, Y, Yusupov, M.
Deposit date:2023-03-08
Release date:2024-09-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
To Be Published
8CQ7
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BU of 8cq7 by Molmil
Crystal structure of phyllanthoside bound to the Candida albicans 80S ribosome
Descriptor: 18S, 25S, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ...
Authors:Kolosova, O, Zgadzay, Y, Yusupov, M.
Deposit date:2023-03-03
Release date:2024-09-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
To Be Published
8DU4
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BU of 8du4 by Molmil
Complex between RbBP5-WDR5 and an H2B-ubiquitinated nucleosome
Descriptor: 601 DNA (146-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Niklas, H.A, Rahman, S, Worden, E.J, Wolberger, C.
Deposit date:2022-07-26
Release date:2022-09-21
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Multistate structures of the MLL1-WRAD complex bound to H2B-ubiquitinated nucleosome.
Proc.Natl.Acad.Sci.USA, 119, 2022
8EAZ
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BU of 8eaz by Molmil
HOIL-1/E2-Ub/Ub transthiolation complex
Descriptor: RanBP-type and C3HC4-type zinc finger-containing protein 1, Ubiquitin, Ubiquitin-conjugating enzyme E2 L3, ...
Authors:Wang, X.S, Cotton, T.R, Lechtenberg, B.C.
Deposit date:2022-08-30
Release date:2023-01-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.08 Å)
Cite:The unifying catalytic mechanism of the RING-between-RING E3 ubiquitin ligase family.
Nat Commun, 14, 2023
8EB0
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BU of 8eb0 by Molmil
RNF216/E2-Ub/Ub transthiolation complex
Descriptor: E3 ubiquitin-protein ligase RNF216, SULFATE ION, Ubiquitin, ...
Authors:Cotton, T.R, Wang, X.S, Lechtenberg, B.C.
Deposit date:2022-08-30
Release date:2023-01-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:The unifying catalytic mechanism of the RING-between-RING E3 ubiquitin ligase family.
Nat Commun, 14, 2023
8EVQ
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BU of 8evq by Molmil
Hypopseudouridylated Ribosome bound with TSV IRES, eEF2, GDP, and sordarin, Structure I
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Zhao, Y, Rai, J, Li, H.
Deposit date:2022-10-20
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (2.72 Å)
Cite:Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EVP
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BU of 8evp by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), Structure I
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Zhao, Y, Rai, J, Li, H.
Deposit date:2022-10-20
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (2.38 Å)
Cite:Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EUB
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BU of 8eub by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2 and GDP, Structure I
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S0-A, ...
Authors:Zhao, Y, Rai, J, Li, H.
Deposit date:2022-10-18
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (2.52 Å)
Cite:Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EVR
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BU of 8evr by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2, GDP, and sordarin, Structure II
Descriptor: (1S,3S,3aR,4S,4aR,7R,7aR,8aS)-8a-{[(6-deoxy-4-O-methyl-alpha-D-altropyranosyl)oxy]methyl}-4-formyl-7-methyl-3-(propan-2-yl)decahydro-1,4-methano-s-indacene-3a(1H)-carboxylate, 18S rRNA, 25S rRNA, ...
Authors:Zhao, Y, Rai, J, Li, H.
Deposit date:2022-10-20
Release date:2023-09-06
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EVS
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BU of 8evs by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2 and GDP, Structure II
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Zhao, Y, Rai, J, Li, H.
Deposit date:2022-10-20
Release date:2023-09-06
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EWB
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BU of 8ewb by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2 and GDP, Structure III
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Zhao, Y, Rai, J, Li, H.
Deposit date:2022-10-22
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EWC
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BU of 8ewc by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), Structure II
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Zhao, Y, Rai, J, Li, H.
Deposit date:2022-10-22
Release date:2023-09-06
Method:ELECTRON MICROSCOPY (2.45 Å)
Cite:Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EVT
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BU of 8evt by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES) refined against a composite map
Descriptor: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
Authors:Zhao, Y, Rai, J, Li, H.
Deposit date:2022-10-20
Release date:2023-09-06
Last modified:2023-11-01
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
6Z6M
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BU of 6z6m by Molmil
Cryo-EM structure of human 80S ribosomes bound to EBP1, eEF2 and SERBP1
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R.
Deposit date:2020-05-28
Release date:2020-07-29
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18, 2020
6ZMI
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BU of 6zmi by Molmil
SARS-CoV-2 Nsp1 bound to the human LYAR-80S ribosome complex
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
Deposit date:2020-07-02
Release date:2020-08-19
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369, 2020
6ZUO
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BU of 6zuo by Molmil
Human RIO1(kd)-StHA late pre-40S particle, structural state A (pre 18S rRNA cleavage)
Descriptor: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ...
Authors:Plassart, L, Shayan, R, Plisson-Chastang, C.
Deposit date:2020-07-23
Release date:2021-05-12
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:The final step of 40S ribosomal subunit maturation is controlled by a dual key lock.
Elife, 10, 2021
6ZV6
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BU of 6zv6 by Molmil
Human RIO1(kd)-StHA late pre-40S particle, structural state B (post 18S rRNA cleavage)
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Plassart, L, Shayan, R, Plisson-Chastang, C.
Deposit date:2020-07-24
Release date:2021-05-12
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The final step of 40S ribosomal subunit maturation is controlled by a dual key lock.
Elife, 10, 2021
5XY3
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BU of 5xy3 by Molmil
Large subunit of Trichomonas vaginalis ribosome
Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Li, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N.
Deposit date:2017-07-06
Release date:2017-08-30
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii
Cell Res., 27, 2017
5XXU
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BU of 5xxu by Molmil
Small subunit of Toxoplasma gondii ribosome
Descriptor: 18S RNA, Ribosomal protein eL41, Ribosomal protein eS1, ...
Authors:LI, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N.
Deposit date:2017-07-05
Release date:2017-08-30
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii
Cell Res., 27, 2017
7AI0
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BU of 7ai0 by Molmil
Crystal structure of human MDM2-G443T RING domain homodimer bound to UbcH5B-Ub (Crystal form 1)
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, ...
Authors:Magnussen, H.M, Huang, D.T.
Deposit date:2020-09-25
Release date:2021-01-20
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.559 Å)
Cite:Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant.
J.Mol.Biol., 433, 2021

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數據於2024-11-13公開中

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