6DQN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dqn by Molmil](/molmil-images/mine/6dqn) | Class 1 IP3-bound human type 3 1,4,5-inositol trisphosphate receptor | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION | Authors: | Hite, R.K, Paknejad, N. | Deposit date: | 2018-06-11 | Release date: | 2018-08-01 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
|
|
6DR0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dr0 by Molmil](/molmil-images/mine/6dr0) | Class 5 IP3-bound human type 3 1,4,5-inositol trisphosphate receptor | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION | Authors: | Hite, R.K, Paknejad, N. | Deposit date: | 2018-06-11 | Release date: | 2018-08-01 | Last modified: | 2018-08-15 | Method: | ELECTRON MICROSCOPY (4.47 Å) | Cite: | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
|
|
5X9Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5x9z by Molmil](/molmil-images/mine/5x9z) | Crystal structure of inositol 1,4,5-trisphosphate receptor large cytosolic domain | Descriptor: | Inositol 1,4,5-trisphosphate receptor type 1 | Authors: | Hamada, K, Miyatake, H, Terauchi, A, Mikoshiba, K. | Deposit date: | 2017-03-10 | Release date: | 2017-04-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (7.311 Å) | Cite: | IP3-mediated gating mechanism of the IP3 receptor revealed by mutagenesis and X-ray crystallography Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
6UQK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6uqk by Molmil](/molmil-images/mine/6uqk) | Cryo-EM structure of type 3 IP3 receptor revealing presence of a self-binding peptide | Descriptor: | ZINC ION, inositol 1,4,5-triphosphate receptor, type 3 | Authors: | Azumaya, C.M, Linton, E.A, Risener, C.J, Nakagawa, T, Karakas, E. | Deposit date: | 2019-10-20 | Release date: | 2020-01-15 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.77 Å) | Cite: | Cryo-EM structure of human type-3 inositol triphosphate receptor reveals the presence of a self-binding peptide that acts as an antagonist. J.Biol.Chem., 295, 2020
|
|
6DRC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6drc by Molmil](/molmil-images/mine/6drc) | High IP3 Ca2+ human type 3 1,4,5-inositol trisphosphate receptor | Descriptor: | CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ... | Authors: | Hite, R.K, Paknejad, N. | Deposit date: | 2018-06-11 | Release date: | 2018-08-01 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.92 Å) | Cite: | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
|
|
6DQS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dqs by Molmil](/molmil-images/mine/6dqs) | Class 3 IP3-bound human type 3 1,4,5-inositol trisphosphate receptor | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION | Authors: | Hite, R.K, Paknejad, N. | Deposit date: | 2018-06-11 | Release date: | 2018-08-01 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (4.12 Å) | Cite: | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
|
|
6DQZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6dqz by Molmil](/molmil-images/mine/6dqz) | Class 4 IP3-bound human type 3 1,4,5-inositol trisphosphate receptor | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION | Authors: | Hite, R.K, Paknejad, N. | Deposit date: | 2018-06-11 | Release date: | 2018-08-01 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (6.01 Å) | Cite: | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
|
|
4GP7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4gp7 by Molmil](/molmil-images/mine/4gp7) | Polynucleotide kinase | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CITRIC ACID, MAGNESIUM ION, ... | Authors: | Wang, L.K, Das, U, Smith, P, Shuman, S. | Deposit date: | 2012-08-20 | Release date: | 2012-11-14 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and mechanism of the polynucleotide kinase component of the bacterial Pnkp-Hen1 RNA repair system. Rna, 18, 2012
|
|
4GP6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4gp6 by Molmil](/molmil-images/mine/4gp6) | Polynucleotide kinase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Metallophosphoesterase | Authors: | Wang, L.K, Das, U, Smith, P, Shuman, S. | Deposit date: | 2012-08-20 | Release date: | 2012-11-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure and mechanism of the polynucleotide kinase component of the bacterial Pnkp-Hen1 RNA repair system. Rna, 18, 2012
|
|
5IJR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ijr by Molmil](/molmil-images/mine/5ijr) | X-ray structure of neuropilin-1 b1 domain complexed with Arg-1 ligand. | Descriptor: | DIMETHYL SULFOXIDE, L-HOMOARGININE, Neuropilin-1 | Authors: | Fotinou, C, Rana, R, Djordjevic, S, Yelland, T. | Deposit date: | 2016-03-02 | Release date: | 2017-03-29 | Last modified: | 2018-07-11 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Architecture and hydration of the arginine-binding site of neuropilin-1. FEBS J., 285, 2018
|
|
1YJB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yjb by Molmil](/molmil-images/mine/1yjb) | SUBTILISIN BPN' 8397+1 (E.C. 3.4.21.14) (MUTANT WITH MET 50 REPLACED BY PHE, ASN 76 REPLACED BY ASP, GLY 169 REPLACED BY ALA, GLN 206 REPLACED BY CYS, ASN 218 REPLACED BY SER AND LYS 256 REPLACED BY TYR) (M50F, N76D, G169A, Q206C, N218S, AND K256Y) IN 35% DIMETHYLFORMAMIDE | Descriptor: | CALCIUM ION, SUBTILISIN 8397+1 | Authors: | Kidd, R.D, Farber, G.K. | Deposit date: | 1996-01-16 | Release date: | 1996-07-11 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Breaking the low barrier hydrogen bond in a serine protease. Protein Sci., 8, 1999
|
|
6WI4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wi4 by Molmil](/molmil-images/mine/6wi4) | Caspases from Scleractinian Coral | Descriptor: | ACE-DEVD inhibitor, Caspase-3 | Authors: | Clark, A.C, Swartz, P.D. | Deposit date: | 2020-04-08 | Release date: | 2020-08-26 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Caspases from scleractinian coral show unique regulatory features. J.Biol.Chem., 295, 2020
|
|
1YJA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yja by Molmil](/molmil-images/mine/1yja) | SUBTILISIN BPN' 8397+1 (E.C. 3.4.21.14) (MUTANT WITH MET 50 REPLACED BY PHE, ASN 76 REPLACED BY ASP, GLY 169 REPLACED BY ALA, GLN 206 REPLACED BY CYS, ASN 218 REPLACED BY SER AND LYS 256 REPLACED BY TYR) (M50F, N76D, G169A, Q206C, N218S, AND K256Y) IN 20% DIMETHYLFORMAMIDE | Descriptor: | CALCIUM ION, SUBTILISIN 8397+1 | Authors: | Kidd, R.D, Farber, G.K. | Deposit date: | 1996-01-16 | Release date: | 1996-07-11 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Breaking the low barrier hydrogen bond in a serine protease. Protein Sci., 8, 1999
|
|
1YJC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1yjc by Molmil](/molmil-images/mine/1yjc) | SUBTILISIN BPN' 8397+1 (E.C. 3.4.21.14) (MUTANT WITH MET 50 REPLACED BY PHE, ASN 76 REPLACED BY ASP, GLY 169 REPLACED BY ALA, GLN 206 REPLACED BY CYS, ASN 218 REPLACED BY SER AND LYS 256 REPLACED BY TYR) (M50F, N76D, G169A, Q206C, N218S, AND K256Y) IN 50% DIMETHYLFORMAMIDE | Descriptor: | CALCIUM ION, SUBTILISIN 8397+1 | Authors: | Kidd, R.D, Farber, G.K. | Deposit date: | 1996-01-16 | Release date: | 1996-07-11 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Breaking the low barrier hydrogen bond in a serine protease. Protein Sci., 8, 1999
|
|
1XZZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xzz by Molmil](/molmil-images/mine/1xzz) | Crystal structure of the ligand binding suppressor domain of type 1 inositol 1,4,5-trisphosphate receptor | Descriptor: | GLYCEROL, Inositol 1,4,5-trisphosphate receptor type 1 | Authors: | Bosanac, I, Yamazaki, H, Matsu-ura, T, Michikawa, T, Mikoshiba, K, Ikura, M. | Deposit date: | 2004-11-13 | Release date: | 2005-01-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the ligand binding suppressor domain of type 1 inositol 1,4,5-trisphosphate receptor. Mol.Cell, 17, 2005
|
|
4MDF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mdf by Molmil](/molmil-images/mine/4mdf) | Structure of bacterial polynucleotide kinase Michaelis complex bound to GTP and DNA | Descriptor: | CITRIC ACID, DNA (5'-D(*CP*CP*TP*GP*T)-3'), GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Shuman, S, Das, U, Wang, L.K, Smith, P, Jacewicz, A. | Deposit date: | 2013-08-22 | Release date: | 2013-11-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.727 Å) | Cite: | Structures of bacterial polynucleotide kinase in a Michaelis complex with GTP*Mg2+ and 5'-OH oligonucleotide and a product complex with GDP*Mg2+ and 5'-PO4 oligonucleotide reveal a mechanism of general acid-base catalysis and the determinants of phosphoacceptor recognition. Nucleic Acids Res., 42, 2014
|
|
3T6A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3t6a by Molmil](/molmil-images/mine/3t6a) | Structure of the C-terminal domain of BCAR3 | Descriptor: | (20S)-2,5,8,11,14,17-HEXAMETHYL-3,6,9,12,15,18-HEXAOXAHENICOSANE-1,20-DIOL, Breast cancer anti-estrogen resistance protein 3, UNKNOWN ATOM OR ION | Authors: | Mace, P.D, Robinson, H, Riedl, S.J. | Deposit date: | 2011-07-28 | Release date: | 2011-11-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | NSP-Cas protein structures reveal a promiscuous interaction module in cell signaling. Nat.Struct.Mol.Biol., 18, 2011
|
|
3S4E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3s4e by Molmil](/molmil-images/mine/3s4e) | Crystal Structrue of a Novel Mitogen-activated Protein Kinase Phosphatase, SKRP1 | Descriptor: | Dual specificity protein phosphatase 19, PHOSPHATE ION, SULFATE ION | Authors: | Wei, C.H, Ryu, S.Y, Jeon, Y.H, Jeong, D.G, Kim, S.J, Ryu, S.E. | Deposit date: | 2011-05-19 | Release date: | 2012-04-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.26 Å) | Cite: | Crystal structure of a novel mitogen-activated protein kinase phosphatase, SKRP1. Proteins, 79, 2011
|
|
3MKH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mkh by Molmil](/molmil-images/mine/3mkh) | Podospora anserina Nitroalkane Oxidase | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, NITROALKANE OXIDASE, ... | Authors: | Tormos, J.R, Taylor, A.B, Daubner, S.C, Hart, P.J, Fitzpatrick, P.F. | Deposit date: | 2010-04-14 | Release date: | 2010-06-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.995 Å) | Cite: | Identification of a hypothetical protein from Podospora anserina as a nitroalkane oxidase. Biochemistry, 49, 2010
|
|
4MDE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mde by Molmil](/molmil-images/mine/4mde) | Structure of bacterial polynucleotide kinase product complex bound to GDP and DNA | Descriptor: | DNA (5'-D(P*CP*CP*TP*GP*T)-3'), GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Shuman, S, Das, U, Wang, L.K, Smith, P, Jacewicz, A. | Deposit date: | 2013-08-22 | Release date: | 2013-11-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structures of bacterial polynucleotide kinase in a Michaelis complex with GTP*Mg2+ and 5'-OH oligonucleotide and a product complex with GDP*Mg2+ and 5'-PO4 oligonucleotide reveal a mechanism of general acid-base catalysis and the determinants of phosphoacceptor recognition. Nucleic Acids Res., 42, 2014
|
|
3MP2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3mp2 by Molmil](/molmil-images/mine/3mp2) | |
3A9T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3a9t by Molmil](/molmil-images/mine/3a9t) | X-ray Structure of Bacillus pallidus D-Arabinose Isomerase Complex with L-Fucitol | Descriptor: | D-arabinose isomerase, FUCITOL, MANGANESE (II) ION | Authors: | Takeda, K, Yoshida, H, Izumori, K, Kamitori, S. | Deposit date: | 2009-11-05 | Release date: | 2010-04-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | X-ray structures of Bacillus pallidusd-arabinose isomerase and its complex with l-fucitol. Biochim.Biophys.Acta, 1804, 2010
|
|
4MM3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mm3 by Molmil](/molmil-images/mine/4mm3) | |
3CZ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cz1 by Molmil](/molmil-images/mine/3cz1) | Dimeric crystal structure of a pheromone binding protein from Apis mellifera in complex with the n-butyl benzene sulfonamide at pH 7.0 | Descriptor: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | Authors: | Pesenti, M.E, Spinelli, S, Bezirard, V, Briand, L, Pernollet, J.C, Tegoni, M, Cambillau, C. | Deposit date: | 2008-04-27 | Release date: | 2009-04-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Queen bee pheromone binding protein pH-induced domain swapping favors pheromone release J.Mol.Biol., 390, 2009
|
|
3D75
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d75 by Molmil](/molmil-images/mine/3d75) | Crystal structure of a pheromone binding protein mutant D35N, from Apis mellifera, at pH 5.5 | Descriptor: | N-BUTYL-BENZENESULFONAMIDE, Pheromone-binding protein ASP1 | Authors: | Pesenti, M.E, Spinelli, S, Bezirard, V, Briand, L, Pernollet, J.C, Tegoni, M, Cambillau, C. | Deposit date: | 2008-05-20 | Release date: | 2009-05-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Queen bee pheromone binding protein pH-induced domain swapping favors pheromone release J.Mol.Biol., 390, 2009
|
|