PDB: 83630 resultsInfo pagesStatus searchChemie searchBIRD

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1MS8	Triclinic form of Trypanosoma cruzi trans-sialidase, in complex with 3-deoxy-2,3-dehydro-N-acetylneuraminic acid (DANA) Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, trans-sialidase Authors: Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M. Deposit date: 2002-09-19 Release date: 2003-03-25 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (2 Å) Cite: The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis Mol.Cell, 10, 2002
1MS5	Triclinic form of Trypanosoma cruzi trans-sialidase, soaked with N-acetylneuraminyl-a-2,3-thio-galactoside (NA-S-Gal) Descriptor: trans-sialidase Authors: Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M. Deposit date: 2002-09-19 Release date: 2003-03-25 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (2 Å) Cite: The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis Mol.Cell, 10, 2002
1MS4	Triclinic form of Trypanosoma cruzi trans-sialidase Descriptor: trans-sialidase Authors: Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M. Deposit date: 2002-09-19 Release date: 2003-03-25 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (2.21 Å) Cite: The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis Mol.Cell, 10, 2002
1MS9	Triclinic form of Trypanosoma cruzi trans-sialidase, in complex with lactose Descriptor: beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, trans-sialidase Authors: Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M. Deposit date: 2002-09-19 Release date: 2003-03-25 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (1.58 Å) Cite: The crystal structure and mode of action of trans-sialidase, a key enzyme of Trypanosoma cruzi pathogenesis Mol.Cell, 10, 2002
5AB6	Crystal structure of Trypanosoma brucei SCP2-thiolase like protein (TbSLP) in complex with acetoacetyl-CoA. Descriptor: ACETOACETYL-COENZYME A, SCP2-THIOLASE LIKE PROTEIN, SULFATE ION Authors: Harijan, R.K, Kiema, T.R, Wierenga, R.K. Deposit date: 2015-08-01 Release date: 2016-05-04 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The Scp2-Thiolase-Like Protein (Slp) of Trypanosoma Brucei is an Enzyme Involved in Lipid Metabolism. Proteins, 84, 2016
4P01	Crystal Structure Analysis of Macrophage Migration Inhibitory Factor in complex with N-[(4-cyanophenyl)methyl]methanethioamide Descriptor: CHLORIDE ION, GLYCEROL, ISOPROPYL ALCOHOL, ... Authors: Pantouris, G, Lolis, E. Deposit date: 2014-02-19 Release date: 2014-03-19 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.07 Å) Cite: An Analysis of MIF Structural Features that Control Functional Activation of CD74. Chem.Biol., 22, 2015
4RHK	Crystal structure of T. brucei arginase-like protein in an oxidized form Descriptor: Arginase, GLYCEROL Authors: Hai, Y, Barrett, M.P, Christianson, D.W. Deposit date: 2014-10-02 Release date: 2014-12-31 Last modified: 2015-02-04 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Crystal Structure of an Arginase-like Protein from Trypanosoma brucei That Evolved without a Binuclear Manganese Cluster. Biochemistry, 54, 2015
4PKK	Crystal structure of Macrophage Migration inhibitory factor in complex with furan-2-ylmethyl)imino methanethiol Descriptor: (Z)-[(furan-2-ylmethyl)imino]methanethiol, GLYCEROL, ISOPROPYL ALCOHOL, ... Authors: Pantouris, G, Lolis, E. Deposit date: 2014-05-14 Release date: 2016-05-04 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Crystal structure of Macrophage Migration inhibitory factor with a covalent inhibitor To Be Published
5AB4	Crystal structure of Trypanosoma brucei SCP2-thiolase like protein (TbSLP) form-I. Descriptor: SCP2-THIOLASE LIKE PROTEIN Authors: Harijan, R.K, Kiema, T.R, Wierenga, R.K. Deposit date: 2015-08-01 Release date: 2016-05-04 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.751 Å) Cite: The Scp2-Thiolase-Like Protein (Slp) of Trypanosoma Brucei is an Enzyme Involved in Lipid Metabolism. Proteins, 84, 2016
3ARQ	Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with IDARUBICIN Descriptor: Chitinase A, GLYCEROL, IDARUBICIN Authors: Pantoom, S, Vetter, I.R, Prinz, H, Suginta, W. Deposit date: 2010-12-09 Release date: 2011-04-20 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms J.Biol.Chem., 286, 2011
3ARV	Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with Sanguinarine Descriptor: 13-methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridin-13-ium, Chitinase A, GLYCEROL Authors: Pantoom, S, Vetter, I.R, Prinz, H, Suginta, W. Deposit date: 2010-12-09 Release date: 2011-04-20 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms J.Biol.Chem., 286, 2011
7GTE	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with XST00000646b Descriptor: (5S)-5-(trifluoromethyl)-1,4-diazepane, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.9 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
7GTM	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOOA000543a Descriptor: (4S)-4-hydroxy-2-(propan-2-yl)-3,4-dihydro-1lambda~6~,2-benzothiazine-1,1(2H)-dione, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.72 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
3ARO	Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - apo structure Descriptor: Chitinase A, GLYCEROL Authors: Pantoom, S, Vetter, I.R, Prinz, H, Suginta, W. Deposit date: 2010-12-09 Release date: 2011-04-20 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.22 Å) Cite: Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms J.Biol.Chem., 286, 2011
3ARY	Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with 2-(imidazolin-2-yl)-5-isothiocyanatobenzofuran Descriptor: 2-(5-isothiocyanato-1-benzofuran-2-yl)-4,5-dihydro-1H-imidazole, Chitinase A, GLYCEROL Authors: Pantoom, S, Vetter, I.R, Prinz, H, Suginta, W. Deposit date: 2010-12-09 Release date: 2011-04-20 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms J.Biol.Chem., 286, 2011
7GSB	PanDDA Analysis group deposition -- Crystal structure of PTP1B in complex with FMOPL000438a Descriptor: 1-(4-benzylpiperidin-1-yl)-2-methylpropan-1-one, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 Authors: Mehlman, T, Ginn, H.M, Keedy, D.A. Deposit date: 2024-01-03 Release date: 2024-01-24 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.72 Å) Cite: An expanded view of ligandability in the allosteric enzyme PTP1B from computational reanalysis of large-scale crystallographic data. Biorxiv, 2024
4RHL	Crystal structure of T. brucei arginase-like protein triple mutant S149D/R151H/S226D bound with Mn2+ Descriptor: Arginase, GLYCEROL, MANGANESE (II) ION Authors: Hai, Y, Barrett, M.P, Christianson, D.W. Deposit date: 2014-10-02 Release date: 2014-12-31 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Crystal Structure of an Arginase-like Protein from Trypanosoma brucei That Evolved without a Binuclear Manganese Cluster. Biochemistry, 54, 2015
4RHQ	Crystal structure of T. brucei arginase-like protein double mutant S149D/S153D Descriptor: 1,2-ETHANEDIOL, Arginase, GLYCEROL Authors: Hai, Y, Barrett, M.P, Christianson, D.W. Deposit date: 2014-10-02 Release date: 2014-12-31 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.18 Å) Cite: Crystal Structure of an Arginase-like Protein from Trypanosoma brucei That Evolved without a Binuclear Manganese Cluster. Biochemistry, 54, 2015
4RHM	Crystal structure of T. brucei arginase-like protein quadruple mutant S149D/R151H/S153D/S226D Descriptor: 1,2-ETHANEDIOL, Arginase, GLYCEROL, ... Authors: Hai, Y, Barrett, M.P, Christianson, D.W. Deposit date: 2014-10-02 Release date: 2014-12-31 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal Structure of an Arginase-like Protein from Trypanosoma brucei That Evolved without a Binuclear Manganese Cluster. Biochemistry, 54, 2015
4RHI	Crystal structure of SeMet-labeled wild-type T. brucei arginase-like protein in P321 space group Descriptor: Arginase, GLYCEROL Authors: Hai, Y, Barrett, M.P, Christianson, D.W. Deposit date: 2014-10-02 Release date: 2014-12-31 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Crystal Structure of an Arginase-like Protein from Trypanosoma brucei That Evolved without a Binuclear Manganese Cluster. Biochemistry, 54, 2015
1MS0	Monoclinic form of Trypanosoma cruzi trans-sialidase, in complex with 3-deoxy-2,3-dehydro-N-acetylneuraminic acid (DANA)and lactose Descriptor: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, trans-sialidase Authors: Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M. Deposit date: 2002-09-19 Release date: 2003-03-25 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis Mol.Cell, 10, 2002
1MS3	Monoclinic form of Trypanosoma cruzi trans-sialidase Descriptor: trans-sialidase Authors: Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M. Deposit date: 2002-09-19 Release date: 2003-03-25 Last modified: 2021-10-27 Method: X-RAY DIFFRACTION (1.65 Å) Cite: The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis Mol.Cell, 10, 2002
3ARX	Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with Propentofylline Descriptor: 3-methyl-1-(5-oxohexyl)-7-propyl-3,7-dihydro-1H-purine-2,6-dione, Chitinase A, GLYCEROL Authors: Pantoom, S, Vetter, I.R, Prinz, H, Suginta, W. Deposit date: 2010-12-09 Release date: 2011-04-20 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.16 Å) Cite: Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms J.Biol.Chem., 286, 2011
3ARP	Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with DEQUALINIUM Descriptor: Chitinase A, DEQUALINIUM, GLYCEROL Authors: Pantoom, S, Vetter, I.R, Prinz, H, Suginta, W. Deposit date: 2010-12-09 Release date: 2011-04-20 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms J.Biol.Chem., 286, 2011
3ARW	Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with chelerythrine Descriptor: 1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium, Chitinase A, GLYCEROL Authors: Pantoom, S, Vetter, I.R, Prinz, H, Suginta, W. Deposit date: 2010-12-09 Release date: 2011-04-20 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Potent family-18 chitinase inhibitors: x-ray structures, affinities, and binding mechanisms J.Biol.Chem., 286, 2011

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