2PK0
 
 | | Structure of the S. agalactiae serine/threonine phosphatase at 2.65 resolution | | Descriptor: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Rantanen, M.K, Lehtio, L, Rajagopal, L, Rubens, C.E, Goldman, A. | | Deposit date: | 2007-04-17 | | Release date: | 2007-06-12 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Structure of Streptococcus agalactiae serine/threonine phosphatase. The subdomain conformation is coupled to the binding of a third metal ion
Febs J., 274, 2007
|
|
2PQ5
 | | Crystal structure of Dual specificity protein phosphatase 13 (DUSP13) | | Descriptor: | Dual specificity protein phosphatase 13 | | Authors: | Ugochukwu, E, Salah, E, Savitsky, P, Barr, A, Pantic, N, Niesen, F, Burgess-Brown, N, Berridge, G, Bunkoczi, G, Uppenberg, J, Pike, A.C.W, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A, von Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2007-05-01 | | Release date: | 2007-05-22 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of Dual specificity protein phosphatase 13 (DUSP13).
To be Published
|
|
5GL0
 | | Structure of RyR1 in a closed state (C4 conformer) | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ZINC ION | | Authors: | Bai, X.C, Yan, Z, Wu, J.P, Yan, N. | | Deposit date: | 2016-07-07 | | Release date: | 2016-08-24 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening
Cell Res., 26, 2016
|
|
5GL1
 | | Structure of RyR1 in an open state | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ZINC ION | | Authors: | Bai, X.C, Yan, Z, Wu, J.P, Yan, N. | | Deposit date: | 2016-07-07 | | Release date: | 2016-08-24 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (5.7 Å) | | Cite: | The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening
Cell Res., 26, 2016
|
|
5GKY
 | | Structure of RyR1 in a closed state (C1 conformer) | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ZINC ION | | Authors: | Bai, X.C, Yan, Z, Wu, J.P, Yan, N. | | Deposit date: | 2016-07-07 | | Release date: | 2016-08-24 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening
Cell Res., 26, 2016
|
|
8HLP
 | | Cryo-EM structure of human high-voltage activated L-type calcium channel CaV1.2 (apo) | | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Wei, Y, Yu, Z, Zhao, Y. | | Deposit date: | 2022-11-30 | | Release date: | 2024-04-24 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structural bases of inhibitory mechanism of Ca V 1.2 channel inhibitors.
Nat Commun, 15, 2024
|
|
8HMA
 | | Cryo-EM structure of human high-voltage activated L-type calcium channel CaV1.2 in complex with tetrandrine (TET) | | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 6,6',7,12-tetramethoxy-2,2'-dimethyl-1beta-3,4-didehydroberbaman, ... | | Authors: | Wei, Y, Yu, Z, Zhao, Y. | | Deposit date: | 2022-12-02 | | Release date: | 2024-04-24 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural bases of inhibitory mechanism of Ca V 1.2 channel inhibitors.
Nat Commun, 15, 2024
|
|
2RMO
 | | Solution structure of alpha-spectrin_SH3-bergerac from Chicken | | Descriptor: | Spectrin alpha chain, brain | | Authors: | Kutyshenko, V.P, Prokhorov, D.A, Timchenko, M.A, Kudrevatykh, Y.A, Fedyukina, D.V, Gushchina, L.V, Khristoforov, V.S, Filimonov, V.V. | | Deposit date: | 2007-11-07 | | Release date: | 2008-09-30 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Study of the structure and dynamics of a chimeric variant of the SH3 domain (SHA-Bergerac) by NMR spectroscopy
Russ.J.Bioorganic Chem., 34, 2008
|
|
8I6V
 | | Cryo-EM structure of the polyphosphate polymerase VTC complex(Vtc4/Vtc3/Vtc1) | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, MANGANESE (II) ION, PHOSPHATE ION, ... | | Authors: | Mayer, A, Wu, S, Ye, S. | | Deposit date: | 2023-01-29 | | Release date: | 2023-03-01 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.06 Å) | | Cite: | Cryo-EM structure of the polyphosphate polymerase VTC reveals coupling of polymer synthesis to membrane transit.
Embo J., 42, 2023
|
|
2ROT
 | | Structure of chimeric variant of SH3 domain- SHH | | Descriptor: | Spectrin alpha chain, brain | | Authors: | Kutyshenko, N.P, Prokhorov, D.A, Timchenko, M.A, Kudrevatykh, Y.A, Gushchina, L.V, Khristoforov, V.S, Filimonov, V.V. | | Deposit date: | 2008-04-10 | | Release date: | 2009-04-28 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution structure and dynamics of the chimeric SH3 domains, SHH- and SHA-"Bergeracs".
Biochim.Biophys.Acta, 1794, 2009
|
|
2P27
 | | Crystal Structure of Human Pyridoxal Phosphate Phosphatase with Mg2+ at 1.9 A resolution | | Descriptor: | MAGNESIUM ION, Pyridoxal phosphate phosphatase | | Authors: | Ramagopal, U.A, Freeman, J, Izuka, M, Toro, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2007-03-07 | | Release date: | 2007-03-13 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural genomics of protein phosphatases.
J.Struct.Funct.Genom., 8, 2007
|
|
2RQ8
 | | Solution NMR structure of titin I27 domain mutant | | Descriptor: | Titin | | Authors: | Yagawa, K, Oguro, T, Momose, T, Kawano, S, Sato, T, Endo, T. | | Deposit date: | 2009-03-05 | | Release date: | 2010-02-02 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structural basis for unfolding pathway-dependent stability of proteins: Vectorial unfolding vs. global unfolding
Protein Sci., 2010
|
|
8J6N
 | | Crystal structure of Cystathionine gamma-lyase in complex with compound 1 | | Descriptor: | 1,2-ETHANEDIOL, Cystathionine gamma-lyase, GLYCEROL, ... | | Authors: | Hibi, R, Toma-Fukai, S, Shimizu, T, Hanaoka, K. | | Deposit date: | 2023-04-26 | | Release date: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Discovery of a cystathionine gamma-lyase (CSE) selective inhibitor targeting active-site pyridoxal 5'-phosphate (PLP) via Schiff base formation.
Sci Rep, 13, 2023
|
|
5GJV
 | | Structure of the mammalian voltage-gated calcium channel Cav1.1 complex at near atomic resolution | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Wu, J.P, Yan, Z, Li, Z.Q, Zhou, Q, Yan, N. | | Deposit date: | 2016-07-02 | | Release date: | 2016-09-14 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structure of the voltage-gated calcium channel Cav1.1 at 3.6 angstrom resolution
Nature, 537, 2016
|
|
2V26
 | | Myosin VI (MD) pre-powerstroke state (Mg.ADP.VO4) | | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Menetrey, J, Llinas, P, Mukherjea, M, Sweeney, H.L, Houdusse, A. | | Deposit date: | 2007-06-03 | | Release date: | 2007-11-20 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The Structural Basis for the Large Powerstroke of Myosin Vi.
Cell(Cambridge,Mass.), 131, 2007
|
|
5GJW
 | | Structure of the mammalian voltage-gated calcium channel Cav1.1 complex for ClassII map | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Wu, J.P, Yan, Z, Li, Z.Q, Zhou, Q, Yan, N. | | Deposit date: | 2016-07-02 | | Release date: | 2016-09-14 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structure of the voltage-gated calcium channel Cav1.1 at 3.6 angstrom resolution
Nature, 537, 2016
|
|
5GKZ
 | | Structure of RyR1 in a closed state (C3 conformer) | | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ZINC ION | | Authors: | Bai, X.C, Yan, Z, Wu, J.P, Yan, N. | | Deposit date: | 2016-07-07 | | Release date: | 2016-08-24 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening
Cell Res., 26, 2016
|
|
1N2D
 | | Ternary complex of MLC1P bound to IQ2 and IQ3 of Myo2p, a class V myosin | | Descriptor: | IQ2 AND IQ3 MOTIFS FROM MYO2P, A CLASS V MYOSIN, Myosin Light Chain | | Authors: | Terrak, M, Wu, G, Stafford, W.F, Lu, R.C, Dominguez, R. | | Deposit date: | 2002-10-22 | | Release date: | 2003-11-04 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of the light chain-binding domain of myosin V.
Proc.Natl.Acad.Sci.USA, 102, 2005
|
|
2W4H
 | | Isometrically contracting insect asynchronous flight muscle quick frozen after a quick release step | | Descriptor: | MYOSIN HEAVY CHAIN, SKELETAL MUSCLE, ADULT, ... | | Authors: | Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A. | | Deposit date: | 2008-11-25 | | Release date: | 2010-08-25 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (35 Å) | | Cite: | Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped Following a Mechanical Perturbation.
Plos One, 7, 2012
|
|
2W4A
 | | ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE | | Descriptor: | MYOSIN HEAVY CHAIN, SKELETAL MUSCLE, ADULT, ... | | Authors: | Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A. | | Deposit date: | 2008-11-24 | | Release date: | 2010-04-14 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (35 Å) | | Cite: | Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin Interactions
Plos One, 5, 2010
|
|
4PE5
 | | Crystal Structure of GluN1a/GluN2B NMDA Receptor Ion Channel | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl]phenol, ... | | Authors: | Karakas, E, Furukawa, H. | | Deposit date: | 2014-04-22 | | Release date: | 2014-06-04 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (3.96 Å) | | Cite: | Crystal structure of a heterotetrameric NMDA receptor ion channel.
Science, 344, 2014
|
|
2W4G
 | | ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE QUICK FROZEN AFTER A QUICK STRETCH STEP | | Descriptor: | MYOSIN HEAVY CHAIN, SKELETAL MUSCLE, ADULT, ... | | Authors: | Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A. | | Deposit date: | 2008-11-25 | | Release date: | 2010-08-25 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (35 Å) | | Cite: | Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin Interactions
Plos One, 5, 2010
|
|
2W4T
 | | ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE | | Descriptor: | MYOSIN ESSENTIAL LIGHT CHAIN, STRIATED ADDUCTOR MUSCLE, MYOSIN HEAVY CHAIN, ... | | Authors: | Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A. | | Deposit date: | 2008-12-02 | | Release date: | 2010-01-19 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (35 Å) | | Cite: | Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin Interactions
Plos One, 5, 2010
|
|
2W4U
 | | Isometrically contracting insect asynchronous flight muscle quick frozen after a length step | | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, TROPOMYOSIN ALPHA-1 CHAIN, ... | | Authors: | Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A. | | Deposit date: | 2008-12-02 | | Release date: | 2010-08-25 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (35 Å) | | Cite: | Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped Following a Mechanical Perturbation.
Plos One, 7, 2012
|
|
2W4W
 | | Isometrically contracting insect asynchronous flight muscle quick frozen after a quick stretch step | | Descriptor: | MYOSIN ESSENTIAL LIGHT CHAIN, STRIATED ADDUCTOR MUSCLE, MYOSIN HEAVY CHAIN, ... | | Authors: | Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A. | | Deposit date: | 2008-12-02 | | Release date: | 2010-08-25 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (35 Å) | | Cite: | Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped Following a Mechanical Perturbation.
Plos One, 7, 2012
|
|
