6U9Z
| Wild-type MthK pore in 6 mM K+ | Descriptor: | Calcium-gated potassium channel MthK, HEXANE-1,6-DIOL, POTASSIUM ION | Authors: | Posson, D.J, Nimigean, C.M. | Deposit date: | 2019-09-09 | Release date: | 2020-11-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.954 Å) | Cite: | Selectivity filter ion binding affinity determines inactivation in a potassium channel. Proc.Natl.Acad.Sci.USA, 117, 2020
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6U9Y
| Wild-type MthK pore in 11 mM K+ | Descriptor: | Calcium-gated potassium channel MthK, HEXANE-1,6-DIOL, POTASSIUM ION | Authors: | Posson, D.J, Nimigean, C.M. | Deposit date: | 2019-09-09 | Release date: | 2020-11-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Selectivity filter ion binding affinity determines inactivation in a potassium channel. Proc.Natl.Acad.Sci.USA, 117, 2020
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6U9T
| Wild-type MthK pore in 50 mM K+ | Descriptor: | Calcium-gated potassium channel MthK, HEXANE-1,6-DIOL, POTASSIUM ION | Authors: | Posson, D.J, Nimigean, C.M. | Deposit date: | 2019-09-09 | Release date: | 2020-11-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Selectivity filter ion binding affinity determines inactivation in a potassium channel. Proc.Natl.Acad.Sci.USA, 117, 2020
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6UFE
| The structure of a potassium selective ion channel at atomic resolution | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Transporter | Authors: | Langan, P.S, Vandavasi, V.G, Sullivan, B, Afonine, P.V, Weiss, K.L. | Deposit date: | 2019-09-24 | Release date: | 2020-08-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | The structure of a potassium-selective ion channel reveals a hydrophobic gate regulating ion permeation. Iucrj, 7, 2020
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4PDM
| Crystal Structure of K+ selective NaK mutant in rubidium | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Potassium channel protein, RUBIDIUM ION | Authors: | Lam, Y. | Deposit date: | 2014-04-19 | Release date: | 2014-07-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | High Resolution Structural Views of Rubidium, Cesium and Barium Binding within a Potassium Selective Channel Filter To Be Published
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4PDR
| Crystal Structure of a K+ selective NaK mutant in Barium and Sodium | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, BARIUM ION, Potassium channel protein, ... | Authors: | Lam, Y, Zeng, W, Sauer, D.B, Jiang, Y. | Deposit date: | 2014-04-21 | Release date: | 2014-07-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | High Resolution Structural Views of Rubidium, Cesium and Barium Binding within a Potassium Selective Channel Filter To Be Published
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2ITC
| Potassium Channel KcsA-Fab complex in Sodium Chloride | Descriptor: | Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, SODIUM ION, ... | Authors: | Lockless, S.W, Zhou, M, MacKinnon, R. | Deposit date: | 2006-10-19 | Release date: | 2007-05-15 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural and Thermodynamic Properties of Selective Ion Binding in a K(+) Channel. Plos Biol., 5, 2007
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2HFE
| Rb+ complex of a K channel with an amide to ester substitution in the selectivity filter | Descriptor: | (2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL NONANOATE, FAB Heavy Chain, FAB Light Chain, ... | Authors: | Valiyaveetil, F.I, MacKinnon, R, Muir, T.W. | Deposit date: | 2006-06-23 | Release date: | 2006-09-12 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel. J.Am.Chem.Soc., 128, 2006
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2IH3
| Ion selectivity in a semi-synthetic K+ channel locked in the conductive conformation | Descriptor: | (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, FAB Heavy Chain, FAB Light Chain, ... | Authors: | Valiyaveetil, F.I, Leonetti, M, Muir, T.W, MacKinnon, R. | Deposit date: | 2006-09-25 | Release date: | 2006-11-21 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Ion Selectivity in a Semisynthetic K+ Channel Locked in the Conductive Conformation. Science, 314, 2006
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3PJS
| Mechanism of Activation Gating in the Full-Length KcsA K+ Channel | Descriptor: | FAB heavy chain, FAB light chain, Voltage-gated potassium channel | Authors: | Uysal, S, Cuello, L.G, Kossiakoff, A, Perozo, E. | Deposit date: | 2010-11-10 | Release date: | 2011-07-06 | Last modified: | 2011-08-03 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Mechanism of activation gating in the full-length KcsA K+ channel. Proc.Natl.Acad.Sci.USA, 108, 2011
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2ITD
| Potassium Channel KcsA-Fab complex in Barium Chloride | Descriptor: | BARIUM ION, Voltage-gated potassium channel, antibody Fab fragment heavy chain, ... | Authors: | Lockless, S.W, Zhou, M, MacKinnon, R. | Deposit date: | 2006-10-19 | Release date: | 2007-05-15 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and Thermodynamic Properties of Selective Ion Binding in a K(+) Channel. Plos Biol., 5, 2007
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2JK5
| Potassium Channel KcsA in complex with Tetrabutylammonium in high K | Descriptor: | (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, ... | Authors: | Lenaeus, M.J, Focia, P.J, Wagner, T, Gross, A. | Deposit date: | 2008-08-15 | Release date: | 2009-11-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of Kcsa in Complex with Symmetrical Quaternary Ammonium Compounds Reveal a Hydrophobic Binding Site. Biochemistry, 53, 2014
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4PDV
| Structure of K+ selective NaK mutant in barium and potassium | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, BARIUM ION, POTASSIUM ION, ... | Authors: | Lam, Y, Zeng, W, Sauer, D.B, Jiang, Y. | Deposit date: | 2014-04-22 | Release date: | 2014-07-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.821 Å) | Cite: | High Resolution Structural Views of Rubidium, Cesium and Barium Binding within a Potassium Selective Channel Filter To Be Published
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3T2M
| Crystal Structure of NaK Channel N68D Mutant | Descriptor: | POTASSIUM ION, Potassium channel protein | Authors: | Sauer, D.B, Zeng, W, Raghunathan, S, Jiang, Y. | Deposit date: | 2011-07-22 | Release date: | 2011-10-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.953 Å) | Cite: | Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation. Proc.Natl.Acad.Sci.USA, 108, 2011
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2HVJ
| Crystal structure of KcsA-Fab-TBA complex in low K+ | Descriptor: | (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, NONAN-1-OL, POTASSIUM ION, ... | Authors: | Zhou, Y. | Deposit date: | 2006-07-28 | Release date: | 2007-02-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystallographic Study of the Tetrabutylammonium Block to the KcsA K(+) Channel. J.Mol.Biol., 366, 2007
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2HVK
| crystal structure of the KcsA-Fab-TBA complex in high K+ | Descriptor: | (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, Antibody Fab heavy chain, Antibody Fab light chain, ... | Authors: | Zhou, Y. | Deposit date: | 2006-07-28 | Release date: | 2007-02-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystallographic Study of the Tetrabutylammonium Block to the KcsA K(+) Channel. J.Mol.Biol., 366, 2007
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2IH1
| Ion selectivity in a semi-synthetic K+ channel locked in the conductive conformation | Descriptor: | (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, FAB Heavy Chain, FAB Light Chain, ... | Authors: | Valiyaveetil, F.I, Leonetti, M, Muir, T.W, MacKinnon, R. | Deposit date: | 2006-09-25 | Release date: | 2006-11-21 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Ion Selectivity in a Semisynthetic K+ Channel Locked in the Conductive Conformation. Science, 314, 2006
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4R50
| Crystal Structure of CNG mimicking NaK-ETPP mutant cocrystallized with Li+ | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCINE, Potassium channel protein | Authors: | De March, M, Napolitano, L.M.R, Onesti, S. | Deposit date: | 2014-08-20 | Release date: | 2015-07-01 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels. Proc.Natl.Acad.Sci.USA, 112, 2015
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3T1C
| Crystal Structure of NaK Channel D66Y Mutant | Descriptor: | POTASSIUM ION, Potassium channel protein | Authors: | Sauer, D.B, Zeng, W, Raghunathan, S, Jiang, Y. | Deposit date: | 2011-07-21 | Release date: | 2011-10-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.802 Å) | Cite: | Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation. Proc.Natl.Acad.Sci.USA, 108, 2011
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3STZ
| KcsA potassium channel mutant Y82C with nitroxide spin label | Descriptor: | POTASSIUM ION, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, Voltage-gated potassium channel, ... | Authors: | Raghuraman, H, Cordero-Morales, J, Jogini, V, Perozo, E. | Deposit date: | 2011-07-11 | Release date: | 2012-04-18 | Last modified: | 2012-10-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mechanism of Cd(2+) Coordination during Slow Inactivation in Potassium Channels. Structure, 20, 2012
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4PDL
| Structure of K+ selective NaK mutant in caesium | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CESIUM ION, HEXANE, ... | Authors: | Lam, Y, Zeng, W, Sauer, D.B, Jiang, Y. | Deposit date: | 2014-04-19 | Release date: | 2014-07-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | High Resolution Structural Views of Rubidium, Cesium and Barium Binding within a Potassium Selective Channel Filter To Be Published
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3R65
| MthK channel pore E92Q mutant | Descriptor: | Calcium-gated potassium channel mthK, POTASSIUM ION | Authors: | Shi, N, Zeng, W, Ye, S, Li, Y, Jiang, Y. | Deposit date: | 2011-03-21 | Release date: | 2012-02-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crucial points within the pore as determinants of K+ channel conductance and gating J.Mol.Biol., 411, 2011
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4R7C
| Crystal Structure of CNG mimicking NaK-ETPP mutant cocrystallized with DiMethylammonium | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DIMETHYLAMINE, GLYCINE, ... | Authors: | De March, M, Napolitano, L.M.R, Onesti, S. | Deposit date: | 2014-08-27 | Release date: | 2015-07-01 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels. Proc.Natl.Acad.Sci.USA, 112, 2015
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3T4D
| Crystal Structure of NaK2K Channel Y55F Mutant | Descriptor: | POTASSIUM ION, Potassium channel protein | Authors: | Sauer, D.B, Zeng, W, Raghunathan, S, Jiang, Y. | Deposit date: | 2011-07-25 | Release date: | 2011-10-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation. Proc.Natl.Acad.Sci.USA, 108, 2011
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3T4Z
| Crystal Structure of NaK2K Channel Y55W Mutant | Descriptor: | POTASSIUM ION, Potassium channel protein | Authors: | Sauer, D.B, Zeng, W, Raghunathan, S, Jiang, Y. | Deposit date: | 2011-07-26 | Release date: | 2011-10-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.901 Å) | Cite: | Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation. Proc.Natl.Acad.Sci.USA, 108, 2011
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