PDB: 166 resultsInfo pagesStatus searchChemie searchBIRD

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4DX5	Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop Descriptor: (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, Acriflavine resistance protein B, DARPIN, ... Authors: Eicher, T, Cha, H, Seeger, M.A, Brandstaetter, L, El-Delik, J, Bohnert, J.A, Kern, W.V, Verrey, F, Gruetter, M.G, Diederichs, K, Pos, K.M. Deposit date: 2012-02-27 Release date: 2012-05-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop. Proc.Natl.Acad.Sci.USA, 109, 2012
4CDI	Crystal structure of AcrB-AcrZ complex Descriptor: ACRIFLAVINE RESISTANCE PROTEIN B, PREDICTED PROTEIN Authors: Du, D, James, N, Klimont, E, Luisi, B.F. Deposit date: 2013-10-31 Release date: 2014-04-30 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3.7 Å) Cite: Structure of the Acrab-Tolc Multidrug Efflux Pump. Nature, 509, 2014
4ZIT	Crystal structure of AcrB in P21 space group Descriptor: DODECYL-BETA-D-MALTOSIDE, Multidrug efflux pump subunit AcrB, NICKEL (II) ION Authors: Ababou, A, Koronakis, V. Deposit date: 2015-04-28 Release date: 2016-07-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.296 Å) Cite: Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. Plos One, 11, 2016
4ZJO	Crystal structure of AcrB triple mutant in complex with antibiotic in P21 space group Descriptor: DODECYL-BETA-D-MALTOSIDE, ERYTHROMYCIN A, Multidrug efflux pump subunit AcrB, ... Authors: Ababou, A, Koronakis, V. Deposit date: 2015-04-29 Release date: 2016-07-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. Plos One, 11, 2016
4ZIW	Crystal structure of AcrB deletion mutant in P21 space group Descriptor: DODECYL-BETA-D-MALTOSIDE, Multidrug efflux pump subunit AcrB, NICKEL (II) ION Authors: Ababou, A, Koronakis, V. Deposit date: 2015-04-28 Release date: 2016-07-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.399 Å) Cite: Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. Plos One, 11, 2016
4ZLL	Crystal structure of transporter AcrB triple mutant Descriptor: Multidrug efflux pump subunit AcrB Authors: Ababou, A, Koronakis, V. Deposit date: 2015-05-01 Release date: 2016-09-14 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.36 Å) Cite: Crystal structure of transporter AcrB triple mutant To Be Published
4ZLJ	Crystal structure of transporter AcrB Descriptor: Multidrug efflux pump subunit AcrB Authors: Ababou, A, Koronakis, V. Deposit date: 2015-05-01 Release date: 2016-09-14 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.257 Å) Cite: Crystal structure of transporter AcrB To Be Published
4ZJQ	Crystal structure of AcrB deletion mutant in complex with antibiotic in P21 space group Descriptor: DODECYL-BETA-D-MALTOSIDE, ERYTHROMYCIN A, Multidrug efflux pump subunit AcrB, ... Authors: Ababou, A, Koronakis, V. Deposit date: 2015-04-29 Release date: 2016-07-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.592 Å) Cite: Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. Plos One, 11, 2016
4ZJL	Crystal structure of AcrB in complex with antibiotic in P21 space group Descriptor: DODECYL-BETA-D-MALTOSIDE, ERYTHROMYCIN A, Multidrug efflux pump subunit AcrB, ... Authors: Ababou, A, Koronakis, V. Deposit date: 2015-04-29 Release date: 2016-07-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.47 Å) Cite: Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. Plos One, 11, 2016
4ZLN	Crystal structure of transporter AcrB deletion mutant Descriptor: Multidrug efflux pump subunit AcrB Authors: Ababou, A, Koronakis, V. Deposit date: 2015-05-01 Release date: 2016-09-14 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.557 Å) Cite: Crystal structure of transporter AcrB deletion mutant To Be Published
4ZIV	Crystal structure of AcrB triple mutant in P21 space group Descriptor: DODECYL-BETA-D-MALTOSIDE, Multidrug efflux pump subunit AcrB, NICKEL (II) ION Authors: Ababou, A, Koronakis, V. Deposit date: 2015-04-28 Release date: 2016-07-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.16 Å) Cite: Structures of Gate Loop Variants of the AcrB Drug Efflux Pump Bound by Erythromycin Substrate. Plos One, 11, 2016
7KF8	Cryo-electron microscopy structure of the heavy metal efflux pump CusA in a heterogeneous 2 open and 1 closed protomer conformation Descriptor: COPPER (I) ION, Cation efflux system protein CusA Authors: Moseng, M.A. Deposit date: 2020-10-13 Release date: 2021-04-14 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3 Å) Cite: Cryo-EM Structures of CusA Reveal a Mechanism of Metal-Ion Export. Mbio, 12, 2021
7KF5	Cryo-electron microscopy structure of the heavy metal efflux pump CusA in the symmetric closed state Descriptor: Cation efflux system protein CusA Authors: Moseng, M.A. Deposit date: 2020-10-13 Release date: 2021-04-14 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Cryo-EM Structures of CusA Reveal a Mechanism of Metal-Ion Export. Mbio, 12, 2021
7KGI	Cryo-EM Structures of AdeB from Acinetobacter baumannii: AdeB-ET-III Descriptor: ETHIDIUM, Efflux pump membrane transporter, PHOSPHATIDYLETHANOLAMINE Authors: Morgan, C.E, Yu, E.W. Deposit date: 2020-10-16 Release date: 2021-03-10 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.34 Å) Cite: Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates. Mbio, 12, 2021
7KGE	Cryo-EM Structures of AdeB from Acinetobacter baumannii: AdeB-II Descriptor: Efflux pump membrane transporter, PHOSPHATIDYLETHANOLAMINE Authors: Morgan, C.E, Yu, E.W. Deposit date: 2020-10-16 Release date: 2021-03-10 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.21 Å) Cite: Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates. Mbio, 12, 2021
7KGF	Cryo-EM Structures of AdeB from Acinetobacter baumannii: AdeB-III Descriptor: Efflux pump membrane transporter Authors: Morgan, C.E, Yu, E.W. Deposit date: 2020-10-16 Release date: 2021-03-10 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.42 Å) Cite: Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates. Mbio, 12, 2021
7KGH	Cryo-EM Structures of AdeB from Acinetobacter baumannii: AdeB-ET-II Descriptor: ETHIDIUM, Efflux pump membrane transporter, PHOSPHATIDYLETHANOLAMINE Authors: Morgan, C.E, Yu, E.W. Deposit date: 2020-10-16 Release date: 2021-03-10 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.79 Å) Cite: Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates. Mbio, 12, 2021
7KGD	Cryo-EM Structures of AdeB from Acinetobacter baumannii: AdeB-I Descriptor: Efflux pump membrane transporter, PHOSPHATIDYLETHANOLAMINE Authors: Morgan, C.E, Yu, E.W. Deposit date: 2020-10-16 Release date: 2021-03-10 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.64 Å) Cite: Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates. Mbio, 12, 2021
7KGG	Cryo-EM Structures of AdeB from Acinetobacter baumannii: AdeB-ET-I Descriptor: ETHIDIUM, Efflux pump membrane transporter, PHOSPHATIDYLETHANOLAMINE Authors: Morgan, C.E, Yu, E.W. Deposit date: 2020-10-16 Release date: 2021-03-10 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (2.97 Å) Cite: Cryoelectron Microscopy Structures of AdeB Illuminate Mechanisms of Simultaneous Binding and Exporting of Substrates. Mbio, 12, 2021
7KF6	Cryo-electron microscopy structure of the heavy metal efflux pump CusA in a homogeneous binding copper(1) state Descriptor: COPPER (I) ION, Cation efflux system protein CusA Authors: Moseng, M.A. Deposit date: 2020-10-13 Release date: 2021-04-14 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Cryo-EM Structures of CusA Reveal a Mechanism of Metal-Ion Export. Mbio, 12, 2021
7KF7	Cryo-electron microscopy structure of the heavy metal efflux pump CusA in a heterogeneous 1 open and 2 closed protomer conformation Descriptor: COPPER (I) ION, Cation efflux system protein CusA Authors: Moseng, M.A. Deposit date: 2020-10-13 Release date: 2021-04-14 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Cryo-EM Structures of CusA Reveal a Mechanism of Metal-Ion Export. Mbio, 12, 2021
8F4R	Gentamicin bound aminoglycoside efflux pump AcrD Descriptor: (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, Efflux pump membrane transporter Authors: Zhang, Z. Deposit date: 2022-11-11 Release date: 2022-12-28 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.06 Å) Cite: Cryo-EM Structures of AcrD Illuminate a Mechanism for Capturing Aminoglycosides from Its Central Cavity. Mbio, 14, 2023
8F56	Dimer of aminoglycoside efflux pump AcrD treated with gentamicin Descriptor: Efflux pump membrane transporter Authors: Zhang, Z. Deposit date: 2022-11-11 Release date: 2022-12-28 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.98 Å) Cite: Cryo-EM Structures of AcrD Illuminate a Mechanism for Capturing Aminoglycosides from Its Central Cavity. Mbio, 14, 2023
8F4N	Dimer of aminoglycoside efflux pump AcrD Descriptor: Efflux pump membrane transporter Authors: Zhang, Z. Deposit date: 2022-11-11 Release date: 2022-12-28 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (2.95 Å) Cite: Cryo-EM Structures of AcrD Illuminate a Mechanism for Capturing Aminoglycosides from Its Central Cavity. Mbio, 14, 2023
8F3E	Trimer of aminoglycoside efflux pump AcrD Descriptor: Efflux pump membrane transporter Authors: Zhang, Z. Deposit date: 2022-11-10 Release date: 2022-12-28 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.09 Å) Cite: Cryo-EM Structures of AcrD Illuminate a Mechanism for Capturing Aminoglycosides from Its Central Cavity. Mbio, 14, 2023

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