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6VKQ
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BU of 6vkq by Molmil
Crystal Structure of human PARP-1 CAT domain bound to inhibitor EB-47
Descriptor: 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide, Poly [ADP-ribose] polymerase 1, SULFATE ION
Authors:Steffen, J.D, Pascal, J.M.
Deposit date:2020-01-21
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for allosteric PARP-1 retention on DNA breaks.
Science, 368, 2020
6VKK
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BU of 6vkk by Molmil
Crystal Structure of human PARP-1 CAT domain bound to inhibitor rucaparib
Descriptor: GLYCEROL, Poly [ADP-ribose] polymerase 1, Rucaparib, ...
Authors:Steffen, J.D, Pascal, J.M.
Deposit date:2020-01-21
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for allosteric PARP-1 retention on DNA breaks.
Science, 368, 2020
6N05
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BU of 6n05 by Molmil
Structure of anti-crispr protein, AcrIIC2
Descriptor: AcrIIC2
Authors:Shah, M, Thavalingham, A, Maxwell, K.L, Moraes, T.F.
Deposit date:2018-11-06
Release date:2019-06-05
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
6VKO
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BU of 6vko by Molmil
Crystal Structure of human PARP-1 CAT domain bound to inhibitor UKTT15
Descriptor: Poly [ADP-ribose] polymerase 1, SULFATE ION, methyl 2-{4-[4-(7-carbamoyl-1H-benzimidazol-2-yl)benzene-1-carbonyl]piperazin-1-yl}pyrimidine-5-carboxylate
Authors:Langelier, M.F, Pascal, J.M.
Deposit date:2020-01-21
Release date:2020-06-17
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for allosteric PARP-1 retention on DNA breaks.
Science, 368, 2020
3RJP
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BU of 3rjp by Molmil
Crystal structure of the DNA binding domain of CovR from Streptococcus pyogenes
Descriptor: CovR
Authors:Horstmann, N.M, Brennan, R.G, Shelburne, S.A.
Deposit date:2011-04-15
Release date:2012-04-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the DNA binding domain of CovR from Streptococcus pyogenes
To be Published
1N2W
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BU of 1n2w by Molmil
Solution Structure of 8OG:G mismatch containing duplex
Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(8OG)P*GP*CP*G)-3'
Authors:Thiviyanathan, V, Somasunderam, A.D, Hazra, T.K, Mitra, S, Gorenstein, D.G.
Deposit date:2002-10-24
Release date:2002-11-13
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution Structure of a DNA Duplex Containing 8-Hydroxy-2'-Deoxyguanosine Opposite Deoxyguanosine
J.Mol.Biol., 325, 2003
3N4Q
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BU of 3n4q by Molmil
Human cytomegalovirus terminase nuclease domain, Mn soaked
Descriptor: MAGNESIUM ION, MANGANESE (II) ION, TERMINASE SUBUNIT UL89 PROTEIN
Authors:Nadal, M, Mas, P.J, Blanco, A.G, Arnan, C, Sola, M, Hart, D.J, Coll, M.
Deposit date:2010-05-22
Release date:2010-10-13
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure and inhibition of herpesvirus DNA packaging terminase nuclease domain.
Proc.Natl.Acad.Sci.USA, 107, 2010
5K5A
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BU of 5k5a by Molmil
Structure of the pNOB8-like ParB N-domain
Descriptor: ParB domain protein nuclease
Authors:Schumacher, M.
Deposit date:2016-05-23
Release date:2016-06-15
Method:X-RAY DIFFRACTION (2.825 Å)
Cite:Structures of archaeal DNA segregation machinery reveal bacterial and eukaryotic linkages.
Science, 349, 2015
4M6W
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BU of 4m6w by Molmil
Crystal structure of the C-terminal segment of FANCM in complex with FAAP24
Descriptor: Fanconi anemia group M protein, Fanconi anemia-associated protein of 24 kDa, SULFATE ION
Authors:Yang, H, Zhang, T, Tong, L, Ding, J.
Deposit date:2013-08-11
Release date:2013-10-02
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural insights into the functions of the FANCM-FAAP24 complex in DNA repair.
Nucleic Acids Res., 41, 2013
1Q8R
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BU of 1q8r by Molmil
Structure of E.coli RusA Holliday junction resolvase
Descriptor: Crossover junction endodeoxyribonuclease rusA
Authors:Rafferty, J.B, Bolt, E.L, Muranova, T.A, Sedelnikova, S.E, Leonard, P, Pasquo, A, Baker, P.J, Rice, D.W, Sharples, G.J, Lloyd, R.G.
Deposit date:2003-08-22
Release date:2004-01-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.899 Å)
Cite:The structure of Escherichia coli RusA endonuclease reveals a new Holliday junction DNA binding fold
Structure, 11, 2003
3HA6
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BU of 3ha6 by Molmil
Crystal structure of aurora A in complex with TPX2 and compound 10
Descriptor: N~2~-(3,4-dimethoxyphenyl)-N~4~-[2-(2-fluorophenyl)ethyl]-N~6~-quinolin-6-yl-1,3,5-triazine-2,4,6-triamine, Serine/threonine-protein kinase 6, Targeting protein for Xklp2
Authors:Zhao, B, Clark, M.A.
Deposit date:2009-05-01
Release date:2009-08-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Design, synthesis and selection of DNA-encoded small-molecule libraries.
Nat.Chem.Biol., 5, 2009
3N4P
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BU of 3n4p by Molmil
Human cytomegalovirus terminase nuclease domain
Descriptor: MAGNESIUM ION, Terminase subunit UL89 protein
Authors:Nadal, M, Mas, P.J, Blanco, A.G, Arnan, C, Sola, M, Hart, D.J, Coll, M.
Deposit date:2010-05-22
Release date:2010-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure and inhibition of herpesvirus DNA packaging terminase nuclease domain.
Proc.Natl.Acad.Sci.USA, 107, 2010
1N9S
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BU of 1n9s by Molmil
Crystal structure of yeast SmF in spacegroup P43212
Descriptor: Small nuclear ribonucleoprotein F
Authors:Collins, B.M, Cubeddu, L, Naidoo, N, Harrop, S.J, Kornfeld, G.D, Dawes, I.W, Curmi, P.M.G, Mabbutt, B.C.
Deposit date:2002-11-26
Release date:2002-12-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Homomeric ring assemblies of eukaryotic Sm proteins have affinity for both RNA and DNA: Crystal structure of an oligomeric complex of yeast SmF
J.Biol.Chem., 278, 2003
1N96
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BU of 1n96 by Molmil
DIMERIC SOLUTION STRUCTURE OF THE CYCLIC OCTAMER CD(CGCTCATT)
Descriptor: CYCLIC OLIGONUCLEOTIDE D(CGCTCATT)
Authors:Escaja, N, Gelpi, J.L, Orozco, M, Rico, M, Pedroso, E, Gonzalez, C.
Deposit date:2002-11-22
Release date:2003-05-13
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Four-stranded DNA structure stabilized by a novel G:C:A:T tetrad.
J.Am.Chem.Soc., 125, 2003
1N9R
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BU of 1n9r by Molmil
Crystal structure of a heptameric ring complex of yeast SmF in spacegroup P4122
Descriptor: Small nuclear ribonucleoprotein F
Authors:Collins, B.M, Cubeddu, L, Naidoo, N, Harrop, S.J, Kornfeld, G.D, Dawes, I.W, Curmi, P.M.G, Mabbutt, B.C.
Deposit date:2002-11-26
Release date:2002-12-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Homomeric ring assemblies of eukaryotic Sm proteins have affinity for both RNA and DNA: Crystal structure of an oligomeric complex of yeast SmF
J.Biol.Chem., 278, 2003
8OK9
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BU of 8ok9 by Molmil
Heterodimeric complex of Archaeoglobus fulgidus Argonaute protein Af1318 (AfAgo) with DNA and AfAgo-N protein containing N-L1-L2 domains
Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, Archaeoglobus fulgidus AfAgo-N protein, ...
Authors:Manakova, E.N, Zaremba, M.
Deposit date:2023-03-27
Release date:2024-01-24
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The missing part: the Archaeoglobus fulgidus Argonaute forms a functional heterodimer with an N-L1-L2 domain protein.
Nucleic Acids Res., 52, 2024
8OZ7
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BU of 8oz7 by Molmil
Abortive infection DNA polymerase AbiA from Lactococcus lactis
Descriptor: AbiA, DNA (5'-D(*AP*AP*AP*AP*AP*AP*AP*AP*T)-3'), MAGNESIUM ION
Authors:Gapinska, M.A, Nowotny, M.
Deposit date:2023-05-08
Release date:2024-04-03
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure-functional characterization of Lactococcus AbiA phage defense system.
Nucleic Acids Res., 52, 2024
3CG7
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BU of 3cg7 by Molmil
Crystal structure of cell-death related nuclease 4 (CRN-4)
Descriptor: Cell death-related nuclease 4, ZINC ION
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2008-03-05
Release date:2008-12-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of CRN-4: implications for domain function in apoptotic DNA degradation
Mol.Cell.Biol., 29, 2009
1U5K
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BU of 1u5k by Molmil
Recombinational repair protein RecO
Descriptor: ZINC ION, hypothetical protein
Authors:Makharashvili, N, Koroleva, O, Bera, S, Grandgenett, D.P, Korolev, S.
Deposit date:2004-07-27
Release date:2004-10-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Novel Structure of DNA Repair Protein RecO from Deinococcus radiodurans
STRUCTURE, 12, 2004
3CM5
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BU of 3cm5 by Molmil
Crystal structure of Cell-Death Related Nuclease 4 (CRN-4) bound with Mn
Descriptor: Cell death-related nuclease 4, MANGANESE (II) ION, ZINC ION
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2008-03-21
Release date:2008-12-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Crystal structure of CRN-4: implications for domain function in apoptotic DNA degradation
Mol.Cell.Biol., 29, 2009
4FDG
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BU of 4fdg by Molmil
Crystal Structure of an Archaeal MCM Filament
Descriptor: Minichromosome maintenance protein MCM, ZINC ION
Authors:Slaymaker, I.M, Fu, Y, Brewster, A.B, Chen, X.S.
Deposit date:2012-05-28
Release date:2013-03-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology.
Nucleic Acids Res., 41, 2013
3WX4
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BU of 3wx4 by Molmil
CRYSTAL STRUCTURE of T4 PHAGE ARN PROTEIN
Descriptor: Anti-restriction endonuclease
Authors:Ho, C.H, Wang, H.C, Ko, T.P, Wang, A.H.J.
Deposit date:2014-07-16
Release date:2014-08-20
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The T4 phage DNA mimic protein Arn inhibits the DNA binding activity of the bacterial histone-like protein H-NS
J.Biol.Chem., 289, 2014
3ZFK
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BU of 3zfk by Molmil
N-terminal truncated Nuclease Domain of Colicin E7
Descriptor: ACETATE ION, CHLORIDE ION, COLICIN-E7, ...
Authors:Toth, E, Czene, A, Gyurcsik, B, Otten, H, Poulsen, J.-C.N, Larsen, S, Christensen, H.E.M, Nagata, K.
Deposit date:2012-12-11
Release date:2013-12-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A New Insight Into the Zinc-Dependent DNA-Cleavage by the Colicin E7 Nuclease: A Crystallographic and Computational Study.
Metallomics, 6, 2014
3CM6
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BU of 3cm6 by Molmil
Crystal structure of cell-death related nuclease 4 (CRN-4) bound with Er
Descriptor: Cell death-related nuclease 4, ERBIUM (III) ION, ZINC ION
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2008-03-21
Release date:2008-12-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of CRN-4: implications for domain function in apoptotic DNA degradation
Mol.Cell.Biol., 29, 2009
3RSN
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BU of 3rsn by Molmil
Crystal Structure of the N-terminal region of Human Ash2L
Descriptor: Set1/Ash2 histone methyltransferase complex subunit ASH2, ZINC ION
Authors:Chen, Y, Wan, B, Wang, K.C, Cao, F, Yang, Y, Protacio, A, Dou, Y, Chang, H.Y, Lei, M.
Deposit date:2011-05-02
Release date:2011-06-22
Last modified:2011-12-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding.
Embo Rep., 12, 2011

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數據於2024-09-04公開中

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