1WB9
| Crystal Structure of E. coli DNA Mismatch Repair enzyme MutS, E38T mutant, in complex with a G.T mismatch | Descriptor: | 5'-D(*AP*CP*TP*GP*GP*TP*GP*CP*TP*TP *GP*GP*CP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP *CP*AP*CP*CP*AP*GP*TP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Natrajan, G, Georgijevic, D, Lebbink, J.H.G, Winterwerp, H.H.K, de Wind, N, Sixma, T.K. | Deposit date: | 2004-10-31 | Release date: | 2006-01-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Dual Role of Muts Glutamate 38 in DNA Mismatch Discrimination and in the Authorization of Repair. Embo J., 25, 2006
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7MKO
| Escherichia coli RNA polymerase elongation complex | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (29-MER), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Qayyum, M.Z, Murakami, K.S. | Deposit date: | 2021-04-26 | Release date: | 2021-06-02 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Structural basis of RNA polymerase recycling by the Swi2/Snf2 family of ATPase RapA in Escherichia coli. J.Biol.Chem., 297, 2021
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7MKN
| Escherichia coli RNA polymerase and RapA elongation complex | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (29-MER), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Qayyum, M.Z, Murakami, K.S. | Deposit date: | 2021-04-26 | Release date: | 2021-06-02 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis of RNA polymerase recycling by the Swi2/Snf2 family of ATPase RapA in Escherichia coli. J.Biol.Chem., 297, 2021
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7MKQ
| Escherichia coli RNA polymerase and RapA binary complex | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Qayyum, M.Z, Murakami, K.S. | Deposit date: | 2021-04-26 | Release date: | 2021-06-02 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structural basis of RNA polymerase recycling by the Swi2/Snf2 family of ATPase RapA in Escherichia coli. J.Biol.Chem., 297, 2021
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4BSS
| Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in P21 crystal form | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, ... | Authors: | Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P. | Deposit date: | 2013-06-11 | Release date: | 2013-06-19 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5. Cell Rep., 3, 2013
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3VE0
| Crystal structure of Sudan Ebolavirus Glycoprotein (strain Boniface) bound to 16F6 | Descriptor: | 16F6 Antibody chain A, 16F6 Antibody chain B, Envelope glycoprotein, ... | Authors: | Saphire, E.O, Bale, S, Dias, J.M. | Deposit date: | 2012-01-06 | Release date: | 2012-04-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.353 Å) | Cite: | Structural basis for differential neutralization of ebolaviruses. Viruses, 4, 2012
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3GGR
| Crystal Structure of the Human Rad9-Hus1-Rad1 complex | Descriptor: | Cell cycle checkpoint control protein RAD9A, Cell cycle checkpoint protein RAD1, Checkpoint protein HUS1 | Authors: | Xu, M, Bai, L, Hang, H.Y, Jiang, T. | Deposit date: | 2009-03-02 | Release date: | 2009-06-16 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure and functional implications of the human rad9-hus1-rad1 cell cycle checkpoint complex J.Biol.Chem., 284, 2009
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4BSU
| Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in C2 crystal form | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, ... | Authors: | Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P. | Deposit date: | 2013-06-11 | Release date: | 2013-06-26 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5. Cell Rep., 3, 2013
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3GBB
| X-ray structure of iGluR5 ligand-binding core (S1S2) in complex with MSVIII-19 at 2.10A resolution | Descriptor: | (2R,3aR,7aR)-2-[(2S)-2-amino-3-hydroxy-3-oxo-propyl]-3,3a,5,6,7,7a-hexahydrofuro[4,5-b]pyran-2-carboxylic acid, Glutamate receptor, ionotropic kainate 1 | Authors: | Frydenvang, K, Naur, P, Gajhede, M, Kastrup, J.S. | Deposit date: | 2009-02-19 | Release date: | 2009-03-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Full Domain Closure of the Ligand-binding Core of the Ionotropic Glutamate Receptor iGluR5 Induced by the High Affinity Agonist Dysiherbaine and the Functional Antagonist 8,9-Dideoxyneodysiherbaine J.Biol.Chem., 284, 2009
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3GAB
| C-terminal domain of Bacillus subtilis MutL crystal form I | Descriptor: | DNA mismatch repair protein mutL | Authors: | Guarne, A, Pillon, M.C, Lorenowicz, J.J, Mitchell, R.R, Chung, Y.S, Friedhoff, P. | Deposit date: | 2009-02-17 | Release date: | 2010-07-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the endonuclease domain of MutL: unlicensed to cut. Mol.Cell, 39, 2010
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1WBD
| Crystal structure of E. coli DNA mismatch repair enzyme MutS, E38Q mutant, in complex with a G.T mismatch | Descriptor: | 5'-D(*AP*CP*TP*GP*GP*TP*GP*CP*TP*TP *GP*GP*CP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP *CP*AP*CP*CP*AP*GP*TP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Natrajan, G, Georgijevic, D, Lebbink, J.H.G, Winterwerp, H.H.K, de Wind, N, Sixma, T.K. | Deposit date: | 2004-10-31 | Release date: | 2006-01-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Dual Role of Muts Glutamate 38 in DNA Mismatch Discrimination and in the Authorization of Repair. Embo J., 25, 2006
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1WBB
| Crystal structure of E. coli DNA mismatch repair enzyme MutS, E38A mutant, in complex with a G.T mismatch | Descriptor: | 5'-D(*AP*CP*TP*GP*GP*TP*GP*CP*TP*TP *GP*GP*CP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP *CP*AP*CP*CP*AP*GP*TP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Natrajan, G, Georgijevic, D, Lebbink, J.H.G, Winterwerp, H.H.K, de Wind, N, Sixma, T.K. | Deposit date: | 2004-10-31 | Release date: | 2006-01-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Dual Role of Muts Glutamate 38 in DNA Mismatch Discrimination and in the Authorization of Repair. Embo J., 25, 2006
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3U10
| Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | Authors: | Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A. | Deposit date: | 2011-09-29 | Release date: | 2011-10-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels. J.Biol.Chem., 286, 2011
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6CEG
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3UT0
| Crystal structure of exo-1,3/1,4-beta-glucanase (EXOP) from Pseudoalteromonas sp. BB1 | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Exo-1,3/1,4-beta-glucanase, ... | Authors: | Nakatani, Y, Cutfield, S.M, Cutfield, J.F. | Deposit date: | 2011-11-24 | Release date: | 2011-12-21 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and activity of exo-1,3/1,4-beta-glucanase from marine bacterium Pseudoalteromonas sp. BB1 showing a novel C-terminal domain Febs J., 2011
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7MKP
| Escherichia coli RNA polymerase core enzyme | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Qayyum, M.Z, Murakami, K.S. | Deposit date: | 2021-04-26 | Release date: | 2021-06-23 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Structural basis of RNA polymerase recycling by the Swi2/Snf2 family of ATPase RapA in Escherichia coli. J.Biol.Chem., 297, 2021
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7M5M
| PCNA bound to peptide mimetic | Descriptor: | N-BUTANE, Peptide mimetic (ACE)RQCSMTCFYHSK(NH2) with linker, Proliferating cell nuclear antigen | Authors: | Vandborg, B.A, Bruning, J.B. | Deposit date: | 2021-03-24 | Release date: | 2021-08-11 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A cell permeable bimane-constrained PCNA-interacting peptide. Rsc Chem Biol, 2, 2021
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7M5L
| PCNA bound to peptide mimetic with linker | Descriptor: | PROPANE, Peptide mimetic (ACE)RQCSMTCFYHSK(NH2) with linker, Proliferating cell nuclear antigen | Authors: | Vandborg, B.A, Bruning, J.B. | Deposit date: | 2021-03-24 | Release date: | 2021-08-11 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A cell permeable bimane-constrained PCNA-interacting peptide. Rsc Chem Biol, 2, 2021
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7M5N
| PCNA bound to peptide mimetic with linker | Descriptor: | 1,3-dimethylbenzene, Peptide mimetic (ACE)RQCSMTCFYHSK(NH2) with linker, Proliferating cell nuclear antigen | Authors: | Vandborg, B.A, Bruning, J.B. | Deposit date: | 2021-03-24 | Release date: | 2021-08-11 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | A cell permeable bimane-constrained PCNA-interacting peptide. Rsc Chem Biol, 2, 2021
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6E6A
| Triclinic crystal form of IncA G144A point mutant | Descriptor: | Inclusion membrane protein A, SODIUM ION | Authors: | Cingolani, G, Paumet, F. | Deposit date: | 2018-07-24 | Release date: | 2019-07-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis for the homotypic fusion of chlamydial inclusions by the SNARE-like protein IncA. Nat Commun, 10, 2019
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6EE8
| Mycobacterium tuberculosis RNAP promoter unwinding intermediate complex with RbpA/CarD and AP3 promoter | Descriptor: | DNA (60-MER), DNA (65-MER), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J. | Deposit date: | 2018-08-13 | Release date: | 2018-11-21 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.92 Å) | Cite: | Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding. Nature, 565, 2019
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7KQ1
| PCNA bound to truncated peptide mimetic | Descriptor: | LYS-ARG-ARG-GLN-THR-SER-MET-THR-ASP-PHE-TYR-HIS-SER-LYS-ARG, Proliferating cell nuclear antigen | Authors: | Vandborg, B.A, Bruning, J.B. | Deposit date: | 2020-11-13 | Release date: | 2021-05-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Unlocking the PIP-box: A peptide library reveals interactions that drive high-affinity binding to human PCNA. J.Biol.Chem., 296, 2021
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7KQ0
| PCNA bound to peptide mimetic | Descriptor: | LYS-ARG-ARG-GLN-THR-SER-MET-THR-ASP-TYR-TYR-HIS-SER-LYS-ARG, Proliferating cell nuclear antigen | Authors: | Vandborg, B.A, Bruning, J.B. | Deposit date: | 2020-11-13 | Release date: | 2021-05-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Unlocking the PIP-box: A peptide library reveals interactions that drive high-affinity binding to human PCNA. J.Biol.Chem., 296, 2021
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1XMU
| Catalytic Domain Of Human Phosphodiesterase 4B In Complex With Roflumilast | Descriptor: | 3-(CYCLOPROPYLMETHOXY)-N-(3,5-DICHLOROPYRIDIN-4-YL)-4-(DIFLUOROMETHOXY)BENZAMIDE, MAGNESIUM ION, ZINC ION, ... | Authors: | Card, G.L, England, B.P, Suzuki, Y, Fong, D, Powell, B, Lee, B, Luu, C, Tabrizizad, M, Gillette, S, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J. | Deposit date: | 2004-10-04 | Release date: | 2004-12-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases. STRUCTURE, 12, 2004
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1XOQ
| Catalytic Domain Of Human Phosphodiesterase 4D In Complex With Roflumilast | Descriptor: | 1,2-ETHANEDIOL, 3-(CYCLOPROPYLMETHOXY)-N-(3,5-DICHLOROPYRIDIN-4-YL)-4-(DIFLUOROMETHOXY)BENZAMIDE, MAGNESIUM ION, ... | Authors: | Card, G.L, England, B.P, Suzuki, Y, Fong, D, Powell, B, Lee, B, Luu, C, Tabrizizad, M, Gillette, S, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J. | Deposit date: | 2004-10-06 | Release date: | 2004-12-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases. STRUCTURE, 12, 2004
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