4GWS
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![BU of 4gws by Molmil](/molmil-images/mine/4gws) | Crystal Structure of AMP complexes of Porcine Liver Fructose-1,6-bisphosphatase with Filled Central Cavity | Descriptor: | 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, ... | Authors: | Gao, Y, Honzatko, R.B. | Deposit date: | 2012-09-03 | Release date: | 2013-09-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Hydrophobic Central Cavity in Fructose-1,6-bisphosphatase is Essential for the Synergism in AMP/Fructose 2,6-bisphosphate Inhibition To be Published
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1B2Z
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![BU of 1b2z by Molmil](/molmil-images/mine/1b2z) | DELETION OF A BURIED SALT BRIDGE IN BARNASE | Descriptor: | PROTEIN (BARNASE), ZINC ION | Authors: | Vaughan, C.K, Harryson, P, Buckle, A.M, Oliveberg, M, Fersht, A.R. | Deposit date: | 1998-12-03 | Release date: | 1998-12-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | A structural double-mutant cycle: estimating the strength of a buried salt bridge in barnase. Acta Crystallogr.,Sect.D, 58, 2002
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2BET
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![BU of 2bet by Molmil](/molmil-images/mine/2bet) | Structure of Mycobacterium tuberculosis Ribose-5-Phosphate Isomerase, RpiB, Rv2465c, in complex with 4-phospho-D-erythronate. | Descriptor: | 4-PHOSPHO-D-ERYTHRONATE, CARBOHYDRATE-PHOSPHATE ISOMERASE | Authors: | Roos, A.K, Ericsson, D.J, Mowbray, S.L. | Deposit date: | 2004-11-30 | Release date: | 2004-12-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Competitive Inhibitors of Mycobacterium Tuberculosis Ribose-5-Phosphate Isomerase B Reveal New Information About the Reaction Mechanism J.Biol.Chem., 280, 2005
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2KM0
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![BU of 2km0 by Molmil](/molmil-images/mine/2km0) | Cu(I)-bound CopK | Descriptor: | COPPER (I) ION, Copper resistance protein K | Authors: | Bersch, B. | Deposit date: | 2009-07-15 | Release date: | 2010-03-16 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | CopK from Cupriavidus metallidurans CH34 Binds Cu(I) in a Tetrathioether Site: Characterization by X-ray Absorption and NMR Spectroscopy J.Am.Chem.Soc., 2010
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2KN4
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![BU of 2kn4 by Molmil](/molmil-images/mine/2kn4) | The structure of the RRM domain of SC35 | Descriptor: | Immunoglobulin G-binding protein G,Serine/arginine-rich splicing factor 2 | Authors: | Clayton, J.C, Goult, B.T, Lian, L.-Y. | Deposit date: | 2009-08-14 | Release date: | 2010-08-18 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | The structure and selectivity of the SR protein SRSF2 RRM domain with RNA Nucleic Acids Res., 2011
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1B20
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![BU of 1b20 by Molmil](/molmil-images/mine/1b20) | DELETION OF A BURIED SALT-BRIDGE IN BARNASE | Descriptor: | PROTEIN (BARNASE), ZINC ION | Authors: | Vaughan, C.K, Harryson, P, Buckle, A.M, Oliveberg, M, Fersht, A.R. | Deposit date: | 1998-12-03 | Release date: | 1998-12-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A structural double-mutant cycle: estimating the strength of a buried salt bridge in barnase. Acta Crystallogr.,Sect.D, 58, 2002
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1B21
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![BU of 1b21 by Molmil](/molmil-images/mine/1b21) | DELETION OF A BURIED SALT BRIDGE IN BARNASE | Descriptor: | PROTEIN (BARNASE), ZINC ION | Authors: | Vaughan, C.K, Harryson, P, Buckle, A.M, Oliveberg, M, Fersht, A.R. | Deposit date: | 1998-12-03 | Release date: | 1998-12-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A structural double-mutant cycle: estimating the strength of a buried salt bridge in barnase. Acta Crystallogr.,Sect.D, 58, 2002
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7A4Q
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![BU of 7a4q by Molmil](/molmil-images/mine/7a4q) | The Crystal structure of RO4613269 bound to CK2alpha | Descriptor: | 2-methoxyimino-5-(quinolin-6-ylmethyl)-1,3-thiazol-4-one, Casein kinase II subunit alpha | Authors: | Brear, P, Hyvonen, M. | Deposit date: | 2020-08-20 | Release date: | 2022-06-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Chemical proteomics reveals the target landscape of 1,000 kinase inhibitors. Nat.Chem.Biol., 2023
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2KSK
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2EVN
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![BU of 2evn by Molmil](/molmil-images/mine/2evn) | NMR solution structures of At1g77540 | Descriptor: | Protein At1g77540 | Authors: | Tyler, R.C, Singh, S, Tonelli, M, Min, M.S, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2005-10-31 | Release date: | 2005-11-15 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of Arabidopsis thaliana At1g77540 Protein, a Minimal Acetyltransferase from the COG2388 Family. Biochemistry, 45, 2006
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5FHV
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![BU of 5fhv by Molmil](/molmil-images/mine/5fhv) | Crystal structure of mCherry after reaction with 2-mercaptoethanol | Descriptor: | BETA-MERCAPTOETHANOL, HEXAETHYLENE GLYCOL, TRIETHYLENE GLYCOL, ... | Authors: | De Zitter, E, Dedecker, P, Van Meervelt, L. | Deposit date: | 2015-12-22 | Release date: | 2017-01-11 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Efficient switching of mCherry fluorescence using chemical caging. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1VH2
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1VH9
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![BU of 1vh9 by Molmil](/molmil-images/mine/1vh9) | Crystal structure of a putative thioesterase | Descriptor: | Hypothetical protein ybdB | Authors: | Structural GenomiX | Deposit date: | 2003-12-01 | Release date: | 2003-12-30 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural analysis of a set of proteins resulting from a bacterial genomics project Proteins, 60, 2005
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6DX1
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![BU of 6dx1 by Molmil](/molmil-images/mine/6dx1) | Crystal structure of the viral OTU domain protease from Qalyub virus | Descriptor: | RNA-dependent RNA polymerase | Authors: | Dzimianski, J.V, Beldon, B.S, Daczkowski, C.M, Goodwin, O.Y, Pegan, S.D. | Deposit date: | 2018-06-28 | Release date: | 2018-12-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.652 Å) | Cite: | Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity. PLoS Pathog., 15, 2019
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6DGM
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![BU of 6dgm by Molmil](/molmil-images/mine/6dgm) | Streptococcus pyogenes phosphoglycerol transferase GacH in complex with sn-glycerol-1-phosphate | Descriptor: | CALCIUM ION, MANGANESE (II) ION, Phosphoglycerol transferase GacH, ... | Authors: | Edgar, R.J, Korotkova, N, Korotkov, K.V. | Deposit date: | 2018-05-17 | Release date: | 2018-06-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides. Nat.Chem.Biol., 15, 2019
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2M4Q
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![BU of 2m4q by Molmil](/molmil-images/mine/2m4q) | NMR structure of E. coli ribosomela decoding site with apramycin | Descriptor: | APRAMYCIN, RNA (27-MER) | Authors: | Puglisi, J.D, Tsai, A, Marshall, R, Viani, E. | Deposit date: | 2013-02-10 | Release date: | 2013-03-20 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | The impact of aminoglycosides on the dynamics of translation elongation. Cell Rep, 3, 2013
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6DKO
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![BU of 6dko by Molmil](/molmil-images/mine/6dko) | Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 2,6-F-phenyldiketoacid | Descriptor: | 4-(2,6-difluorophenyl)-2,4-dioxobutanoic acid, MAGNESIUM ION, Malate synthase G | Authors: | Krieger, I.V, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2018-05-30 | Release date: | 2018-09-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.556 Å) | Cite: | Anion-pi Interactions in Computer-Aided Drug Design: Modeling the Inhibition of Malate Synthase by Phenyl-Diketo Acids. J Chem Inf Model, 58, 2018
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7NHZ
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6DNP
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![BU of 6dnp by Molmil](/molmil-images/mine/6dnp) | Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 2-F-3-Methyl-6-F-phenyldiketoacid | Descriptor: | (2Z)-4-(2,6-difluoro-3-methylphenyl)-2-hydroxy-4-oxobut-2-enoic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, ... | Authors: | Krieger, I.V, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC), Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) | Deposit date: | 2018-06-07 | Release date: | 2018-09-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.711 Å) | Cite: | Anion-pi Interactions in Computer-Aided Drug Design: Modeling the Inhibition of Malate Synthase by Phenyl-Diketo Acids. J Chem Inf Model, 58, 2018
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2M7T
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![BU of 2m7t by Molmil](/molmil-images/mine/2m7t) | Solution NMR Structure of Engineered Cystine Knot Protein 2.5D | Descriptor: | Cystine Knot Protein 2.5D | Authors: | Cochran, F.V, Das, R. | Deposit date: | 2013-04-30 | Release date: | 2014-05-07 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Challenging the state of the art in protein structure prediction: Highlights of experimental target structures for the 10th Critical Assessment of Techniques for Protein Structure Prediction Experiment CASP10. Proteins, 82 Suppl 2, 2014
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4XEZ
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![BU of 4xez by Molmil](/molmil-images/mine/4xez) | |
2MG9
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![BU of 2mg9 by Molmil](/molmil-images/mine/2mg9) | Truncated EGF-A | Descriptor: | CALCIUM ION, Low-density lipoprotein receptor | Authors: | Schroeder, C.I, Rosengren, K. | Deposit date: | 2013-10-30 | Release date: | 2014-04-02 | Method: | SOLUTION NMR | Cite: | Design and Synthesis of Truncated EGF-A Peptides that Restore LDL-R Recycling in the Presence of PCSK9 In Vitro. Chem.Biol., 21, 2014
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4XET
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![BU of 4xet by Molmil](/molmil-images/mine/4xet) | Fe-Cl bound Y157F CDO at pH ~7.0 in the presence of azide | Descriptor: | CHLORIDE ION, Cysteine dioxygenase type 1, FE (III) ION | Authors: | Driggers, C.M, Karplus, P.A. | Deposit date: | 2014-12-24 | Release date: | 2016-04-06 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structure-Based Insights into the Role of the Cys-Tyr Crosslink and Inhibitor Recognition by Mammalian Cysteine Dioxygenase. J. Mol. Biol., 428, 2016
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4XF0
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![BU of 4xf0 by Molmil](/molmil-images/mine/4xf0) | |
5HVM
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![BU of 5hvm by Molmil](/molmil-images/mine/5hvm) | Structure of Aspergillus fumigatus trehalose-6-phosphate synthase A in complex with UDP and validoxylamine A | Descriptor: | (1S,2S,3R,6S)-4-(HYDROXYMETHYL)-6-{[(1S,2S,3S,4R,5R)-2,3,4-TRIHYDROXY-5-(HYDROXYMETHYL)CYCLOHEXYL]AMINO}CYCLOHEX-4-ENE-1,2,3-TRIOL, Alpha,alpha-trehalose-phosphate synthase (UDP-forming), URIDINE-5'-DIPHOSPHATE | Authors: | Miao, Y, Brennan, R.G. | Deposit date: | 2016-01-28 | Release date: | 2017-05-03 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.815 Å) | Cite: | Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design. MBio, 8, 2017
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