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5YWZ
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BU of 5ywz by Molmil
AID-SUN tandem of SUN1
Descriptor: SUN domain-containing protein 1
Authors:Xu, Y, Li, W, Feng, W.
Deposit date:2017-11-30
Release date:2018-02-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural conservation of the autoinhibitory domain in SUN proteins
Biochem. Biophys. Res. Commun., 496, 2018
5X4X
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BU of 5x4x by Molmil
Mutant human thymidylate synthase A191K crystallized in a sulfate-containing condition
Descriptor: SULFATE ION, Thymidylate synthase
Authors:Chen, D, Jansson, A, Larsson, A, Nordlund, P.
Deposit date:2017-02-14
Release date:2017-06-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states
J. Biol. Chem., 292, 2017
5X4W
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BU of 5x4w by Molmil
Mutant human thymidylate synthase A191K crystallized in a sulfate-free condition
Descriptor: PHOSPHATE ION, Thymidylate synthase
Authors:Chen, D, Jansson, A, Larsson, A, Nordlund, P.
Deposit date:2017-02-14
Release date:2017-06-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states
J. Biol. Chem., 292, 2017
2ORM
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BU of 2orm by Molmil
Crystal Structure of the 4-Oxalocrotonate Tautomerase Homologue DmpI from Helicobacter pylori.
Descriptor: Probable tautomerase HP0924
Authors:Hackert, M.L, Whitman, C.P, Almrud, J.J, Dasgupta, R, Czerwinski, R.M, Kern, A.D.
Deposit date:2007-02-03
Release date:2008-02-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Kinetic and structural characterization of DmpI from Helicobacter pylori and Archaeoglobus fulgidus, two 4-oxalocrotonate tautomerase family members.
Bioorg.Chem., 38, 2010
4B53
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BU of 4b53 by Molmil
Crystal structure of the isolated IgG4 CH3 domain
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ...
Authors:Davies, A.M, Rispens, T, den Bleker, T.H, McDonnell, J.M, Gould, H.J, Aalberse, R.C, Sutton, B.J.
Deposit date:2012-08-02
Release date:2012-12-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the Human Igg4 C(H)3 Dimer Reveals the Role of Arg409 in the Mechanism of Fab-Arm Exchange.
Mol.Immunol., 54, 2012
5WG1
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BU of 5wg1 by Molmil
Kelch domain of human Keap1 bound to mutant Nrf2 EAGE peptide
Descriptor: Kelch-like ECH-associated protein 1, Nrf2 EAGE mutant peptide, SULFATE ION
Authors:Carolan, J.P, Lynch, A.J, Allen, K.N.
Deposit date:2017-07-13
Release date:2018-09-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.021 Å)
Cite:Interaction Energetics and Druggability of the Protein-Protein Interaction between Kelch-like ECH-Associated Protein 1 (KEAP1) and Nuclear Factor Erythroid 2 Like 2 (Nrf2).
Biochemistry, 59, 2020
5WFV
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BU of 5wfv by Molmil
Kelch domain of human Keap1 bound to Nrf2 ETGE peptide
Descriptor: Kelch-like ECH-associated protein 1, Nrf2 ETGE peptide, SULFATE ION
Authors:Carolan, J.P, Lynch, A.J, Allen, K.N.
Deposit date:2017-07-12
Release date:2018-09-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Interaction Energetics and Druggability of the Protein-Protein Interaction between Kelch-like ECH-Associated Protein 1 (KEAP1) and Nuclear Factor Erythroid 2 Like 2 (Nrf2).
Biochemistry, 59, 2020
5WHO
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BU of 5who by Molmil
Kelch domain of human Keap1 bound to small molecule inhibitor fragment: 4-oxo-4H-1-benzopyran-2-carboxylic acid
Descriptor: 4-oxo-4H-1-benzopyran-2-carboxylic acid, Kelch-like ECH-associated protein 1, SULFATE ION
Authors:Carolan, J.P, Lynch, A.J, Allen, K.N.
Deposit date:2017-07-17
Release date:2018-09-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Interaction Energetics and Druggability of the Protein-Protein Interaction between Kelch-like ECH-Associated Protein 1 (KEAP1) and Nuclear Factor Erythroid 2 Like 2 (Nrf2).
Biochemistry, 59, 2020
1XP4
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BU of 1xp4 by Molmil
Crystal structure of a peptidoglycan synthesis regulatory factor (PBP3) from Streptococcus pneumoniae
Descriptor: D-alanyl-D-alanine carboxypeptidase, IODIDE ION, SULFATE ION
Authors:Morlot, C, Pernot, L, Le Gouellec, A, Di Guilmi, A.M, Vernet, T, Dideberg, O, Dessen, A.
Deposit date:2004-10-08
Release date:2004-11-09
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of a peptidoglycan synthesis regulatory factor (PBP3) from Streptococcus pneumoniae
J.Biol.Chem., 280, 2005
4O5P
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BU of 4o5p by Molmil
Crystal structure of an uncharacterized protein from Pseudomonas aeruginosa
Descriptor: Uncharacterized protein
Authors:Hu, H.D, Gao, Z.Q, Zhang, H, Dong, Y.H.
Deposit date:2013-12-19
Release date:2014-08-13
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structure of the type VI secretion phospholipase effector Tle1 provides insight into its hydrolysis and membrane targeting.
Acta Crystallogr.,Sect.D, 70, 2014
5DD8
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BU of 5dd8 by Molmil
The Crystal structure of HucR mutant (HucR-E48Q) from Deinococcus radiodurans
Descriptor: CHLORIDE ION, Transcriptional regulator, MarR family
Authors:Deochand, D.K, Perera, I.C, Crochet, R.B, Gilbert, N.C, Newcomer, M.E, Grove, A.
Deposit date:2015-08-24
Release date:2015-09-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Histidine switch controlling pH-dependent protein folding and DNA binding in a transcription factor at the core of synthetic network devices.
Mol Biosyst, 12, 2016
2PHN
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BU of 2phn by Molmil
Crystal structure of an amide bond forming F420-gamma glutamyl ligase from Archaeoglobus fulgidus
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, F420-0:gamma-glutamyl ligase, ...
Authors:Nocek, B, Evdokimova, E, Kudritska, M, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2007-04-11
Release date:2007-05-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure of an Amide Bond Forming F(420):gammagamma-glutamyl Ligase from Archaeoglobus Fulgidus - A Member of a New Family of Non-ribosomal Peptide Synthases.
J.Mol.Biol., 372, 2007
2WV1
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BU of 2wv1 by Molmil
CRYSTAL STRUCTURE OF THE HLYIIR MUTANT PROTEIN WITH RESIDUES 169-186 SUBSTITUTED BY A LINKER CONTAINING TWO THROMBIN SITES
Descriptor: HEMOLYSIN II REGULATORY PROTEIN, NITRATE ION
Authors:Kovalevskiy, O.V, Solonin, A.S, Antson, A.A.
Deposit date:2009-10-12
Release date:2009-10-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Investigation of Transcriptional Regulator Hlyiir: Influence of a Disordered Region on Protein Fold and Dimerization.
Proteins, 78, 2010
1V0R
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BU of 1v0r by Molmil
Tungstate-inhibited phospholipase D from Streptomyces sp. strain PMF
Descriptor: PHOSPHOLIPASE D, TUNGSTATE(VI) ION
Authors:Leiros, I, McSweeney, S, Hough, E.
Deposit date:2004-04-01
Release date:2004-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Reaction Mechanism of Phospholipase D from Streptomyces Sp. Strain Pmf. Snapshots Along the Reaction Pathway Reveal a Pentacoordinate Reaction Intermediate and an Unexpected Final Product
J.Mol.Biol., 339, 2004
1V7Z
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BU of 1v7z by Molmil
creatininase-product complex
Descriptor: MANGANESE (II) ION, N-[(E)-AMINO(IMINO)METHYL]-N-METHYLGLYCINE, SULFATE ION, ...
Authors:Yoshimoto, T, Tanaka, N, Kanada, N, Inoue, T, Nakajima, Y, Haratake, M, Nakamura, K.T, Xu, Y, Ito, K.
Deposit date:2003-12-26
Release date:2004-01-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures of creatininase reveal the substrate binding site and provide an insight into the catalytic mechanism
J.Mol.Biol., 337, 2004
1V0V
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BU of 1v0v by Molmil
Phospholipase D from Streptomyces sp. strain PMF soaked with the substrate dibutyrylphosphatidylcholine.
Descriptor: PHOSPHITE ION, PHOSPHOLIPASE D
Authors:Leiros, I, McSweeney, S, Hough, E.
Deposit date:2004-04-02
Release date:2004-06-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Reaction Mechanism of Phospholipase D from Streptomyces Sp. Strain Pmf. Snapshots Along the Reaction Pathway Reveal a Pentacoordinate Reaction Intermediate and an Unexpected Final Product
J.Mol.Biol., 339, 2004
5E6P
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BU of 5e6p by Molmil
PlexinB2 cytoplasmic region/PDZ-RhoGEF PDZ domain complex
Descriptor: Plexin-B2, Rho guanine nucleotide exchange factor 11
Authors:Pascoe, H.G, Zhang, X.
Deposit date:2015-10-10
Release date:2015-11-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.215 Å)
Cite:Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ-RhoGEF.
Proc.Natl.Acad.Sci.USA, 112, 2015
5ABU
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BU of 5abu by Molmil
Complex of D. melanogaster eIF4E with the 4E-binding protein Mextli and cap analog
Descriptor: 4E-BINDING PROTEIN MEXTLI, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, CHLORIDE ION, ...
Authors:Peter, D, Weichenrieder, O.
Deposit date:2015-08-09
Release date:2015-09-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation
Genes Dev., 29, 2015
3J0A
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BU of 3j0a by Molmil
Homology model of human Toll-like receptor 5 fitted into an electron microscopy single particle reconstruction
Descriptor: Toll-like receptor 5, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Modis, Y, Zhou, K, Kanai, R, Lee, P, Wang, H.W.
Deposit date:2011-06-02
Release date:2011-12-28
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (26 Å)
Cite:Toll-like receptor 5 forms asymmetric dimers in the absence of flagellin.
J.Struct.Biol., 177, 2012
5ABV
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BU of 5abv by Molmil
Complex of D. melanogaster eIF4E with the 4E-binding protein Mextli
Descriptor: EUKARYOTIC TRANSLATION INITIATION FACTOR 4E, GH11071P
Authors:Peter, D, Weichenrieder, O.
Deposit date:2015-08-09
Release date:2015-09-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Mextli Proteins Use Both Canonical Bipartite and Novel Tripartite Binding Modes to Form Eif4E Complexes that Display Differential Sensitivity to 4E-BP Regulation
Genes Dev., 29, 2015
3HPH
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BU of 3hph by Molmil
Closed tetramer of Visna virus integrase (residues 1-219) in complex with LEDGF IBD
Descriptor: GLYCEROL, Integrase, PC4 and SFRS1-interacting protein, ...
Authors:Hare, S, Wang, J, Cherepanov, P.
Deposit date:2009-06-04
Release date:2009-07-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structural basis for functional tetramerization of lentiviral integrase
Plos Pathog., 5, 2009
3HUS
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BU of 3hus by Molmil
Crystal structure of recombinant gamma N308K fibrinogen fragment D with the peptide ligand Gly-Pro-Arg-Pro-amide
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha chain, ...
Authors:Lord, S.T, Bowley, S.R, Okumura, N.
Deposit date:2009-06-15
Release date:2009-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Impaired protofibril formation in fibrinogen gammaN308K is due to altered D:D and "A:a" interactions.
Biochemistry, 48, 2009
5ZXV
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BU of 5zxv by Molmil
Structural definition of a unique neutralization epitope on the receptor-binding domain of MERS-CoV spike glycoprotein
Descriptor: MERS-CoV RBD, heavy chain, light chain
Authors:Zhang, S, Wang, X.
Deposit date:2018-05-21
Release date:2018-07-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (4.482 Å)
Cite:Structural Definition of a Unique Neutralization Epitope on the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein
Cell Rep, 24, 2018
2HQO
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BU of 2hqo by Molmil
Structure of a Atypical Orphan Response Regulator Protein Revealed a New Phosphorylation-Independent Regulatory Mechanism
Descriptor: Putative TRANSCRIPTIONAL REGULATOR
Authors:Hong, E, Lee, W.
Deposit date:2006-07-19
Release date:2007-05-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of an Atypical Orphan Response Regulator Protein Supports a New Phosphorylation-independent Regulatory Mechanism
J.Biol.Chem., 282, 2007
2HQR
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BU of 2hqr by Molmil
Structure of a Atypical Orphan Response Regulator Protein Revealed a New Phosphorylation-Independent Regulatory Mechanism
Descriptor: Putative TRANSCRIPTIONAL REGULATOR
Authors:Hong, E, Lee, W.
Deposit date:2006-07-19
Release date:2007-05-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of an Atypical Orphan Response Regulator Protein Supports a New Phosphorylation-independent Regulatory Mechanism
J.Biol.Chem., 282, 2007

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數據於2024-07-17公開中

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