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8ZFK
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BU of 8zfk by Molmil
Caenorhabditis elegans ACR-23 in betaine and monepantel bound state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Betaine receptor acr-23,Soluble cytochrome b562, ...
Authors:Chen, Q.F, Liu, F.L, Li, T.Y, Gong, H.H, Guo, F, Liu, S.
Deposit date:2024-05-08
Release date:2024-07-31
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Structural basis of acetylcholine receptor like-23 (ACR-23) activation by anthelmintics monepantel and betaine
To Be Published
8ZFM
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BU of 8zfm by Molmil
Caenorhabditis elegans ACR-23 in betaine bound state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Betaine receptor acr-23,Soluble cytochrome b562, ...
Authors:Chen, Q.F, Liu, F.L, Li, T.Y, Gong, H.H, Guo, F, Liu, S.
Deposit date:2024-05-08
Release date:2024-07-31
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Structural basis of acetylcholine receptor like-23 (ACR-23) activation by anthelmintics monepantel and betaine
To Be Published
9AWJ
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BU of 9awj by Molmil
Bovine adult muscle nAChR bound to ACh
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINE, ...
Authors:Li, H, Hibbs, R.E.
Deposit date:2024-03-05
Release date:2024-07-31
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (2.45 Å)
Cite:Structural switch in acetylcholine receptors in developing muscle.
Nature, 632, 2024
9AWK
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BU of 9awk by Molmil
Bovine fetal muscle nAChR resting state
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Li, H, Hibbs, R.E.
Deposit date:2024-03-05
Release date:2024-07-31
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (2.14 Å)
Cite:Structural switch in acetylcholine receptors in developing muscle.
Nature, 632, 2024
9EQG
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BU of 9eqg by Molmil
CryoEM structure of human full-length alpha1beta3gamma2L GABA(A)R in complex with GABA and puerarin
Descriptor: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kasaragod, V.B, Aricescu, A.R.
Deposit date:2024-03-21
Release date:2024-09-18
Last modified:2024-09-25
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:A brain-to-gut signal controls intestinal fat absorption.
Nature, 2024
7T0W
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BU of 7t0w by Molmil
Complex of GABA-A synaptic receptor with autoimmune antibody Fab115
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab115 Heavy Chain, IgG1, ...
Authors:Noviello, C.M, Hibbs, R.E, Kreye, J, Teng, J, Pruss, H.
Deposit date:2021-11-30
Release date:2022-07-13
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural mechanisms of GABA A receptor autoimmune encephalitis.
Cell, 185, 2022
7T0Z
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BU of 7t0z by Molmil
Complex of GABA-A synaptic receptor with autoimmune antibody Fab175
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab175 IgG1 heavy chain, ...
Authors:Noviello, C.M, Hibbs, R.E, Kreye, J, Teng, J, Pruss, H.
Deposit date:2021-11-30
Release date:2022-07-13
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural mechanisms of GABA A receptor autoimmune encephalitis.
Cell, 185, 2022
7SMR
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BU of 7smr by Molmil
Cryo-EM structure of Torpedo acetylcholine receptor in complex with carbachol, desensitized state
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[(AMINOCARBONYL)OXY]-N,N,N-TRIMETHYLETHANAMINIUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E.
Deposit date:2021-10-26
Release date:2022-03-09
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:Structural mechanism of muscle nicotinic receptor desensitization and block by curare.
Nat.Struct.Mol.Biol., 29, 2022
7SMM
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BU of 7smm by Molmil
Cryo-EM structure of Torpedo acetylcholine receptor in apo form
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E.
Deposit date:2021-10-26
Release date:2022-03-09
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural mechanism of muscle nicotinic receptor desensitization and block by curare.
Nat.Struct.Mol.Biol., 29, 2022
7SMQ
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BU of 7smq by Molmil
Cryo-EM structure of Torpedo acetylcholine receptor in apo form with added cholesterol
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E.
Deposit date:2021-10-26
Release date:2022-03-09
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural mechanism of muscle nicotinic receptor desensitization and block by curare.
Nat.Struct.Mol.Biol., 29, 2022
7SMS
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BU of 7sms by Molmil
Cryo-EM structure of Torpedo acetylcholine receptor in complex with d-tubocurarine
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine receptor subunit alpha, ...
Authors:Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E.
Deposit date:2021-10-26
Release date:2022-03-09
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Structural mechanism of muscle nicotinic receptor desensitization and block by curare.
Nat.Struct.Mol.Biol., 29, 2022
7SMT
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BU of 7smt by Molmil
Cryo-EM structure of Torpedo acetylcholine receptor in complex with d-tubocurarine and carbachol
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[(AMINOCARBONYL)OXY]-N,N,N-TRIMETHYLETHANAMINIUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rahman, M.M, Basta, T, Teng, J, Lee, M, Worrell, B.T, Stowell, M.H.B, Hibbs, R.E.
Deposit date:2021-10-26
Release date:2022-03-09
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (2.56 Å)
Cite:Structural mechanism of muscle nicotinic receptor desensitization and block by curare.
Nat.Struct.Mol.Biol., 29, 2022
4BOO
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BU of 4boo by Molmil
The structure and super-organization of acetylcholine receptor-rapsyn complexes class C
Descriptor: ACETYLCHOLINE RECEPTOR BETA SUBUNIT, ACETYLCHOLINE RECEPTOR DELTA SUBUNIT, ACETYLCHOLINE RECEPTOR GAMMA SUBUNIT, ...
Authors:Zuber, B, Unwin, N.
Deposit date:2013-05-21
Release date:2013-06-26
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (42 Å)
Cite:Structure and Superorganization of Acetylcholine Receptor-Rapsyn Complexes.
Proc.Natl.Acad.Sci.USA, 110, 2013
4BOR
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BU of 4bor by Molmil
The structure and super-organization of acetylcholine receptor-rapsyn complexes class D
Descriptor: ACETYLCHOLINE RECEPTOR BETA SUBUNIT, ACETYLCHOLINE RECEPTOR DELTA SUBUNIT, ACETYLCHOLINE RECEPTOR GAMMA SUBUNIT, ...
Authors:Zuber, B, Unwin, N.
Deposit date:2013-05-22
Release date:2013-06-26
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (42 Å)
Cite:Structure and Superorganization of Acetylcholine Receptor-Rapsyn Complexes.
Proc.Natl.Acad.Sci.USA, 110, 2013
4BON
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BU of 4bon by Molmil
The structure and super-organization of acetylcholine receptor-rapsyn complexes class B
Descriptor: ACETYLCHOLINE RECEPTOR BETA SUBUNIT, ACETYLCHOLINE RECEPTOR DELTA SUBUNIT, ACETYLCHOLINE RECEPTOR GAMMA SUBUNIT, ...
Authors:Zuber, B, Unwin, N.
Deposit date:2013-05-21
Release date:2013-06-26
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (40 Å)
Cite:Structure and Superorganization of Acetylcholine Receptor-Rapsyn Complexes.
Proc.Natl.Acad.Sci.USA, 110, 2013
4AQ9
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BU of 4aq9 by Molmil
Gating movement in acetylcholine receptor analysed by time- resolved electron cryo-microscopy (open class)
Descriptor: ACETYLCHOLINE RECEPTOR BETA SUBUNIT, ACETYLCHOLINE RECEPTOR DELTA SUBUNIT, ACETYLCHOLINE RECEPTOR GAMMA SUBUNIT, ...
Authors:Unwin, N, Fujiyoshi, Y.
Deposit date:2012-04-13
Release date:2012-08-01
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Gating Movement of Acetylcholine Receptor Caught by Plunge-Freezing.
J.Mol.Biol., 422, 2012
4BOI
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BU of 4boi by Molmil
The structure and super-organization of acetylcholine receptor-rapsyn complexes class A
Descriptor: ACETYLCHOLINE RECEPTOR BETA SUBUNIT, ACETYLCHOLINE RECEPTOR DELTA SUBUNIT, ACETYLCHOLINE RECEPTOR GAMMA SUBUNIT, ...
Authors:Zuber, B, Unwin, N.
Deposit date:2013-05-20
Release date:2013-06-26
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (41 Å)
Cite:Structure and Superorganization of Acetylcholine Receptor-Rapsyn Complexes.
Proc.Natl.Acad.Sci.USA, 110, 2013
4BOT
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BU of 4bot by Molmil
The structure and super-organization of acetylcholine receptor- rapsyn complexes class E
Descriptor: ACETYLCHOLINE RECEPTOR BETA SUBUNIT, ACETYLCHOLINE RECEPTOR DELTA SUBUNIT, ACETYLCHOLINE RECEPTOR GAMMA SUBUNIT, ...
Authors:Zuber, B, Unwin, N.
Deposit date:2013-05-22
Release date:2013-06-26
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (42 Å)
Cite:Structure and Superorganization of Acetylcholine Receptor-Rapsyn Complexes.
Proc.Natl.Acad.Sci.USA, 110, 2013
4COF
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BU of 4cof by Molmil
Crystal structure of a human gamma-aminobutyric acid receptor, the GABA(A)R-beta3 homopentamer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, BENZAMIDINE, CHLORIDE ION, ...
Authors:Miller, P.S, Aricescu, A.R.
Deposit date:2014-01-28
Release date:2014-06-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Crystal Structure of a Human Gabaa Receptor
Nature, 512, 2014
4AQ5
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BU of 4aq5 by Molmil
Gating movement in acetylcholine receptor analysed by time-resolved electron cryo-microscopy (closed class)
Descriptor: ACETYLCHOLINE RECEPTOR BETA SUBUNIT, ACETYLCHOLINE RECEPTOR DELTA SUBUNIT, ACETYLCHOLINE RECEPTOR GAMMA SUBUNIT, ...
Authors:Unwin, N, Fujiyoshi, Y.
Deposit date:2012-04-12
Release date:2012-08-01
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Gating Movement of Acetylcholine Receptor Caught by Plunge-Freezing.
J.Mol.Biol., 422, 2012
4BOG
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BU of 4bog by Molmil
The structure and super-organization of acetylcholine receptor-rapsyn complexes
Descriptor: Acetylcholine receptor beta subunit, Acetylcholine receptor delta subunit, Acetylcholine receptor gamma subunit, ...
Authors:Zuber, B, Unwin, N.
Deposit date:2013-05-20
Release date:2013-06-26
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (50 Å)
Cite:Structure and Superorganization of Acetylcholine Receptor-Rapsyn Complexes.
Proc.Natl.Acad.Sci.USA, 110, 2013
6I53
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BU of 6i53 by Molmil
Cryo-EM structure of the human synaptic alpha1-beta3-gamma2 GABAA receptor in complex with Megabody38 in a lipid nanodisc
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit alpha-1, ...
Authors:Laverty, D, Desai, R, Uchanski, T, Masiulis, S, Wojciech, J.S, Malinauskas, T, Zivanov, J, Pardon, E, Steyaert, J, Miller, K.W, Aricescu, A.R.
Deposit date:2018-11-12
Release date:2019-01-02
Last modified:2022-03-30
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of the human alpha 1 beta 3 gamma 2 GABAAreceptor in a lipid bilayer.
Nature, 565, 2019
7M6M
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BU of 7m6m by Molmil
Full length alpha1 Glycine receptor in presence of 32uM Tetrahydrocannabinol
Descriptor: (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1
Authors:Kumar, A, Chakrapani, S.
Deposit date:2021-03-26
Release date:2022-08-03
Last modified:2022-09-07
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Structural basis for cannabinoid-induced potentiation of alpha1-glycine receptors in lipid nanodiscs.
Nat Commun, 13, 2022
7M6N
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BU of 7m6n by Molmil
Full length alpha1 Glycine receptor in presence of 0.1mM Glycine
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCINE, Glycine receptor subunit alphaZ1
Authors:Kumar, A, Chakrapani, S.
Deposit date:2021-03-26
Release date:2022-08-03
Last modified:2022-09-07
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Structural basis for cannabinoid-induced potentiation of alpha1-glycine receptors in lipid nanodiscs.
Nat Commun, 13, 2022
7M6Q
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BU of 7m6q by Molmil
Full length alpha1 Glycine receptor in presence of 1mM Glycine and 32uM Tetrahydrocannabinol State 1
Descriptor: (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCINE, ...
Authors:Kumar, A, Chakrapani, S.
Deposit date:2021-03-26
Release date:2022-08-03
Last modified:2022-09-07
Method:ELECTRON MICROSCOPY (2.91 Å)
Cite:Structural basis for cannabinoid-induced potentiation of alpha1-glycine receptors in lipid nanodiscs.
Nat Commun, 13, 2022

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數據於2024-10-09公開中

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