5ZDS
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![BU of 5zds by Molmil](/molmil-images/mine/5zds) | Crystal structure of the second PDZ domain of Frmpd2 | Descriptor: | FERM and PDZ domain-containing 2 | Authors: | Lu, X, Wang, X.F. | Deposit date: | 2018-02-24 | Release date: | 2019-02-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The second PDZ domain of scaffold protein Frmpd2 binds to GluN2A of NMDA receptors. Biochem.Biophys.Res.Commun., 516, 2019
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5A2P
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6ZC3
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![BU of 6zc3 by Molmil](/molmil-images/mine/6zc3) | Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling | Descriptor: | 1,2-ETHANEDIOL, 5-fluoranyl-2-(methylsulfonylamino)benzoic acid, Dishevelled, ... | Authors: | Roske, Y, Heinemann, U, Oschkinat, H. | Deposit date: | 2020-06-09 | Release date: | 2021-06-23 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling J.Magn.Reson., 2021
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6ZBQ
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![BU of 6zbq by Molmil](/molmil-images/mine/6zbq) | Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling | Descriptor: | 5-fluoranyl-2-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonylamino)benzoic acid, Dishevelled, dsh homolog 3 (Drosophila), ... | Authors: | Roske, Y, Heinemann, U, Oschkinat, H. | Deposit date: | 2020-06-09 | Release date: | 2021-06-23 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling J.Magn.Reson., 2021
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6ZBZ
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![BU of 6zbz by Molmil](/molmil-images/mine/6zbz) | Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling | Descriptor: | 1,2-ETHANEDIOL, 2-[(3,4-dimethylphenyl)sulfonylamino]-5-fluoranyl-benzoic acid, Dishevelled, ... | Authors: | Roske, Y, Heinemann, U, Oschkinat, H. | Deposit date: | 2020-06-09 | Release date: | 2021-06-23 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling J.Magn.Reson., 2021
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6ZC8
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6ZC7
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6ZC4
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![BU of 6zc4 by Molmil](/molmil-images/mine/6zc4) | Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling | Descriptor: | 5-bromanyl-2-(5,6,7,8-tetrahydronaphthalen-2-ylsulfonylamino)benzoic acid, Dishevelled, dsh homolog 3 (Drosophila), ... | Authors: | Roske, Y, Heinemann, U, Oschkinat, H. | Deposit date: | 2020-06-09 | Release date: | 2021-06-23 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling J.Magn.Reson., 2021
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6ZC6
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5OAK
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5MZ7
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![BU of 5mz7 by Molmil](/molmil-images/mine/5mz7) | Crystal Structure of the third PDZ domain from the synaptic protein PSD-95 with incorporated Azidohomoalanine | Descriptor: | Disks large homolog 4 | Authors: | Kudlinzki, D, Lehner, F, Witt, K, Linhard, V.L, Silvers, R, Schwalbe, H. | Deposit date: | 2017-01-31 | Release date: | 2017-10-04 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Impact of Azidohomoalanine Incorporation on Protein Structure and Ligand Binding. Chembiochem, 18, 2017
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6JUE
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![BU of 6jue by Molmil](/molmil-images/mine/6jue) | The complex of PDZ and PBM | Descriptor: | Partitioning defective 3 homolog, SULFATE ION, THR-ILE-ILE-THR-LEU | Authors: | Liu, Z. | Deposit date: | 2019-04-13 | Release date: | 2020-04-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.549 Å) | Cite: | Par complex cluster formation mediated by phase separation. Nat Commun, 11, 2020
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6LCB
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![BU of 6lcb by Molmil](/molmil-images/mine/6lcb) | Crystal structure of human Dishevelled1 PDZ domain with its inhibitor NPL3009 | Descriptor: | 2-[[3-[(2E)-2-[1,3-bis(oxidanylidene)-1-phenyl-butan-2-ylidene]hydrazinyl]phenyl]sulfonylamino]benzoic acid, SULFATE ION, Segment polarity protein dishevelled homolog DVL-1 | Authors: | Yasukochi, S, Numoto, N, Tenno, N, Tenno, T, Ito, N, Hiroaki, H. | Deposit date: | 2019-11-18 | Release date: | 2020-11-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of human Dishevelled1 PDZ domain with its inhibitor NPL3009 To Be Published
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6KZ1
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![BU of 6kz1 by Molmil](/molmil-images/mine/6kz1) | Complex structure of Whirlin and Myosin XVa | Descriptor: | Myosin XVa, Whirlin | Authors: | Lin, L, Wang, M, Shi, Y, Zhu, J, Zhang, R. | Deposit date: | 2019-09-22 | Release date: | 2020-09-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.694 Å) | Cite: | Phase separation-mediated condensation of Whirlin-Myo15-Eps8 stereocilia tip complex. Cell Rep, 34, 2021
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6LCA
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![BU of 6lca by Molmil](/molmil-images/mine/6lca) | Crystal structure of human Dishevelled1 PDZ domain homotrimer | Descriptor: | SULFATE ION, Segment polarity protein dishevelled homolog DVL-1 | Authors: | Yasukochi, S, Numoto, N, Tenno, N, Tenno, T, Ito, N, Hiroaki, H. | Deposit date: | 2019-11-18 | Release date: | 2020-11-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of human Dishevelled1 PDZ domain homotrimer To Be Published
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6MTU
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![BU of 6mtu by Molmil](/molmil-images/mine/6mtu) | Crystal structure of human Scribble PDZ1:pMCC complex | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Colorectal mutant cancer protein, ... | Authors: | Caria, S, Stewart, B.Z, Humbert, P.O, Kvansakul, M. | Deposit date: | 2018-10-22 | Release date: | 2019-08-14 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.141 Å) | Cite: | Structural analysis of phosphorylation-associated interactions of human MCC with Scribble PDZ domains. Febs J., 286, 2019
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6MTV
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![BU of 6mtv by Molmil](/molmil-images/mine/6mtv) | Crystal structure of human Scribble PDZ1:MCC complex | Descriptor: | Colorectal mutant cancer protein, DI(HYDROXYETHYL)ETHER, Protein scribble homolog, ... | Authors: | Caria, S, Stewart, B.Z, Humbert, P.O, Kvansakul, M. | Deposit date: | 2018-10-22 | Release date: | 2019-08-14 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.597 Å) | Cite: | Structural analysis of phosphorylation-associated interactions of human MCC with Scribble PDZ domains. Febs J., 286, 2019
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4E34
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![BU of 4e34 by Molmil](/molmil-images/mine/4e34) | Crystal structure of CFTR Associated Ligand (CAL) PDZ domain bound to iCAL36 (ANSRWPTSII) peptide | Descriptor: | GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, decameric peptide, ... | Authors: | Amacher, J.F, Beck, T, Madden, D.R. | Deposit date: | 2012-03-09 | Release date: | 2012-12-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.395 Å) | Cite: | Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains: A NOVEL CONTRIBUTION OF THE CARBOXYLATE-BINDING LOOP. J.Biol.Chem., 288, 2013
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4E3B
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8AH5
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8AH6
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8AH7
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8AH4
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![BU of 8ah4 by Molmil](/molmil-images/mine/8ah4) | |
8AH8
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1G9O
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![BU of 1g9o by Molmil](/molmil-images/mine/1g9o) | FIRST PDZ DOMAIN OF THE HUMAN NA+/H+ EXCHANGER REGULATORY FACTOR | Descriptor: | NHE-RF | Authors: | Karthikeyan, S, Leung, T, Birrane, G, Webster, G, Ladias, J.A.A. | Deposit date: | 2000-11-26 | Release date: | 2001-05-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of the PDZ1 domain of human Na(+)/H(+) exchanger regulatory factor provides insights into the mechanism of carboxyl-terminal leucine recognition by class I PDZ domains. J.Mol.Biol., 308, 2001
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