PDB: 113 resultsInfo pagesStatus searchChemie searchBIRD

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4MV9	Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with Bicarbonate Descriptor: 1,2-ETHANEDIOL, BICARBONATE ION, Biotin carboxylase Authors: Broussard, T.C, Pakhomova, S, Neau, D.B, Champion, T.S, Bonnot, R.J, Waldrop, G.L. Deposit date: 2013-09-23 Release date: 2015-01-14 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase. Biochemistry, 54, 2015
4MV4	Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with AMPPCP and Mg2 Descriptor: 1,2-ETHANEDIOL, Biotin carboxylase, CHLORIDE ION, ... Authors: Broussard, T.C, Pakhomova, S, Neau, D.B, Champion, T.S, Bonnot, R.J, Waldrop, G.L. Deposit date: 2013-09-23 Release date: 2015-01-14 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.61 Å) Cite: Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase. Biochemistry, 54, 2015
4MV1	Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with ADP and Phosphate Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, ... Authors: Broussard, T.C, Pakhomova, S, Neau, D.B, Champion, T.S, Bonnot, R.J, Waldrop, G.L. Deposit date: 2013-09-23 Release date: 2015-01-14 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.91 Å) Cite: Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase. Biochemistry, 54, 2015
3U9T	Crystal structure of P. aeruginosa 3-methylcrotonyl-CoA carboxylase (MCC) 750 kD holoenzyme, free enzyme Descriptor: Methylcrotonyl-CoA carboxylase, alpha-subunit, beta-subunit Authors: Huang, C.S, Tong, L. Deposit date: 2011-10-19 Release date: 2011-12-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.9 Å) Cite: An unanticipated architecture of the 750-kDa {alpha}6{beta}6 holoenzyme of 3-methylcrotonyl-CoA carboxylase Nature, 481, 2012
4MV8	Crystal Structure of Biotin Carboxylase from Haemophilus influenzae in Complex with AMPPCP and Phosphate Descriptor: Biotin carboxylase, PHOSPHATE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER Authors: Broussard, T.C, Pakhomova, S, Neau, D.B, Champion, T.S, Bonnot, R.J, Waldrop, G.L. Deposit date: 2013-09-23 Release date: 2015-01-14 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.06 Å) Cite: Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase. Biochemistry, 54, 2015
3HB9	Crystal Structure of S. aureus Pyruvate Carboxylase A610T Mutant Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... Authors: Tong, L, Yu, L.P.C. Deposit date: 2009-05-04 Release date: 2009-06-30 Last modified: 2021-10-13 Method: X-RAY DIFFRACTION (2.9 Å) Cite: A Symmetrical Tetramer for S. aureus Pyruvate Carboxylase in Complex with Coenzyme A. Structure, 17, 2009
3HBL	Crystal Structure of S. aureus Pyruvate Carboxylase T908A Mutant Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... Authors: Tong, L, Yu, L.P.C. Deposit date: 2009-05-04 Release date: 2009-06-30 Last modified: 2021-10-13 Method: X-RAY DIFFRACTION (2.71 Å) Cite: A Symmetrical Tetramer for S. aureus Pyruvate Carboxylase in Complex with Coenzyme A. Structure, 17, 2009
3TW7	Structure of Rhizobium etli pyruvate carboxylase T882A crystallized without acetyl coenzyme-A Descriptor: CHLORIDE ION, MAGNESIUM ION, Pyruvate carboxylase protein, ... Authors: St Maurice, M, Kumar, S, Lietzan, A.D. Deposit date: 2011-09-21 Release date: 2011-10-12 Last modified: 2011-12-28 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Interaction between the biotin carboxyl carrier domain and the biotin carboxylase domain in pyruvate carboxylase from Rhizobium etli. Biochemistry, 50, 2011
3U9S	Crystal structure of P. aeruginosa 3-methylcrotonyl-CoA carboxylase (MCC) 750 kD holoenzyme, CoA complex Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Methylcrotonyl-CoA carboxylase, ... Authors: Huang, C.S, Tong, L. Deposit date: 2011-10-19 Release date: 2011-12-14 Last modified: 2013-01-23 Method: X-RAY DIFFRACTION (3.5 Å) Cite: An unanticipated architecture of the 750-kDa {alpha}6{beta}6 holoenzyme of 3-methylcrotonyl-CoA carboxylase Nature, 481, 2012
3HO8	Crystal Structure of S. aureus Pyruvate Carboxylase in complex with Coenzyme A Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, MANGANESE (II) ION, ... Authors: Tong, L, Yu, L.P.C. Deposit date: 2009-06-01 Release date: 2009-06-30 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.9 Å) Cite: A Symmetrical Tetramer for S. aureus Pyruvate Carboxylase in Complex with Coenzyme A. Structure, 17, 2009
2V5A	CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 3 Descriptor: 7-(2,5-dihydropyrrol-1-yl)-6-phenyl-pyrido[6,5-d]pyrimidin-2-amine, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-10-02 Release date: 2009-01-13 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.31 Å) Cite: A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore. Proc.Natl.Acad.Sci.USA, 106, 2009
8HZ5	The homodimer of a biotin carboxylase isoform from chloroflexus aurantiacus Descriptor: Biotin carboxylase Authors: Shen, J, Wu, W, Xu, X. Deposit date: 2023-01-08 Release date: 2024-01-10 Last modified: 2024-07-24 Method: X-RAY DIFFRACTION (3 Å) Cite: Chloroflexus aurantiacus acetyl-CoA carboxylase evolves fused biotin carboxylase and biotin carboxyl carrier protein to complete carboxylation activity. Mbio, 15, 2024
8HZ4	The tetrameric structure of biotin carboxylase from Chloroflexus aurantiacus in complex with bicarbonate Descriptor: Biotin carboxylase Authors: Shen, J, Wu, W, Xu, X. Deposit date: 2023-01-08 Release date: 2024-01-10 Last modified: 2024-07-24 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Chloroflexus aurantiacus acetyl-CoA carboxylase evolves fused biotin carboxylase and biotin carboxyl carrier protein to complete carboxylation activity. Mbio, 15, 2024
2W6Z	Crystal structure of Biotin carboxylase from E. coli in complex with the 3-(3-Methyl-but-2-enyl)-3H-purin-6-ylamine fragment Descriptor: 3-(3-methylbut-2-en-1-yl)-3H-purin-6-amine, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-19 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W6O	Crystal structure of Biotin carboxylase from E. coli in complex with 4-Amino-7,7-dimethyl-7,8-dihydro-quinazolinone fragment Descriptor: 4-amino-7,7-dimethyl-7,8-dihydroquinazolin-5(6H)-one, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-18 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W6Q	Crystal structure of Biotin carboxylase from E. coli in complex with the triazine-2,4-diamine fragment Descriptor: 6-(2-phenoxyethoxy)-1,3,5-triazine-2,4-diamine, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-18 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
2W71	Crystal structure of Biotin carboxylase from E. coli in complex with the imidazole-pyrimidine inhibitor Descriptor: 4-[1-(2,6-dichlorobenzyl)-2-methyl-1H-imidazol-4-yl]pyrimidin-2-amine, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-19 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
8J4Z	Human 3-methylcrotonyl-CoA carboxylase in BCCP-CTS state with substrate Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, ... Authors: Liu, D.S, Su, J.Y. Deposit date: 2023-04-21 Release date: 2024-04-24 Method: ELECTRON MICROSCOPY (2.73 Å) Cite: Human 3-methylcrotonyl-CoA carboxylase in BCCP-CTS state with substrate To Be Published
2W70	Crystal structure of Biotin carboxylase from E. coli in complex with the amino-thiazole-pyrimidine fragment Descriptor: 4-(2-amino-1,3-thiazol-4-yl)pyrimidin-2-amine, BIOTIN CARBOXYLASE, CHLORIDE ION Authors: Mochalkin, I, Miller, J.R. Deposit date: 2008-12-19 Release date: 2009-05-19 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Discovery of Antibacterial Biotin Carboxylase Inhibitors by Virtual Screening and Fragment-Based Approaches. Acs Chem.Biol., 4, 2009
8J7O	Human pyruvate carboxylase in BCCP-CTS state without BC Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Pyruvate carboxylase, mitochondrial Authors: Liu, D.S, Su, J.Y. Deposit date: 2023-04-27 Release date: 2024-05-08 Method: ELECTRON MICROSCOPY (3.83 Å) Cite: Human pyruvate carboxylase To Be Published
8J78	Human 3-methylcrotonyl-CoA carboxylase in BCCP-H2 state Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, ... Authors: Liu, D.S, Su, J.Y. Deposit date: 2023-04-27 Release date: 2024-05-08 Method: ELECTRON MICROSCOPY (3.88 Å) Cite: Human 3-methylcrotonyl-CoA carboxylase in BCCP-H2 state To Be Published
8J99	Human 3-methylcrotonyl-CoA carboxylase in BCS-mcoa state Descriptor: Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, Methylcrotonoyl-CoA carboxylase subunit alpha, ... Authors: Liu, D.S, Su, J.Y. Deposit date: 2023-05-02 Release date: 2024-05-08 Method: ELECTRON MICROSCOPY (2.87 Å) Cite: Human 3-methylcrotonyl-CoA carboxylase in BCS-mcoa state To Be Published
8J7D	Human 3-methylcrotonyl-CoA carboxylase in BCCP-H1 state Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, ... Authors: Liu, D.S, Su, J.Y. Deposit date: 2023-04-27 Release date: 2024-05-08 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Human 3-methylcrotonyl-CoA carboxylase in BCCP-H1 state To Be Published
8JAK	Human MCC in MCCU state Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, ... Authors: Liu, D.S, Su, J.Y, Tian, X.Y. Deposit date: 2023-05-06 Release date: 2024-05-15 Method: ELECTRON MICROSCOPY (2.52 Å) Cite: Human MCC in BCCP-BCS state To Be Published
8JAW	Human MCC in MCCD state Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial, ... Authors: Liu, D.S, Su, J.Y, Tian, X.Y. Deposit date: 2023-05-07 Release date: 2024-05-15 Method: ELECTRON MICROSCOPY (2.51 Å) Cite: Human MCC in BCCP-CTS state To Be Published

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