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1OOE	Structural Genomics of Caenorhabditis elegans : Dihydropteridine reductase Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Dihydropteridine reductase Authors: Symersky, J, Li, S, Nagy, L, Qiu, S, Lin, G, Tsao, J, Luo, D, Carson, M, DeLucas, L, Luo, M, Southeast Collaboratory for Structural Genomics (SECSG) Deposit date: 2003-03-03 Release date: 2003-03-18 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structural genomics of Caenorhabditis elegans: structure of dihydropteridine reductase. Proteins, 53, 2003
5WQM	Crystal structure of a carbonyl reductase from Pseudomonas aeruginosa PAO1 (condition I) Descriptor: Probable dehydrogenase, SODIUM ION Authors: Li, S, Wang, Y, Bartlam, M. Deposit date: 2016-11-27 Release date: 2018-07-04 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure and characterization of a NAD(P)H-dependent carbonyl reductase from Pseudomonas aeruginosa PAO1. FEBS Lett., 591, 2017
1NAS	SEPIAPTERIN REDUCTASE COMPLEXED WITH N-ACETYL SEROTONIN Descriptor: N-ACETYL SEROTONIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, OXALOACETATE ION, ... Authors: Auerbach, G, Herrmann, A, Bacher, A, Huber, R. Deposit date: 1998-03-26 Release date: 1999-03-30 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: The 1.25 A crystal structure of sepiapterin reductase reveals its binding mode to pterins and brain neurotransmitters. EMBO J., 16, 1997
6R48	Crystal structure of LPOR (Synechocystis) complexed with NADPH at 1.87A resolution. Descriptor: CHLORIDE ION, Light-dependent protochlorophyllide reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Zhou, A, Feng, L. Deposit date: 2019-03-22 Release date: 2019-10-30 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis. Nature, 574, 2019
8J2C	Structure of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus, mutant N940V/K1106W/S1114R Descriptor: GLYCEROL, L(+)-TARTARIC ACID, Short-chain dehydrogenase/reductase SDR Authors: Ma, Q, Liu, C. Deposit date: 2023-04-14 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structures of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus To Be Published
8J29	Structures of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus Descriptor: GLYCEROL, L(+)-TARTARIC ACID, Short-chain dehydrogenase/reductase SDR Authors: Ma, Q, Liu, C. Deposit date: 2023-04-14 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (1.88 Å) Cite: Structures of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus To Be Published
8J2A	Structure of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus, in complex with NADP+ Descriptor: GLYCEROL, MAGNESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Ma, Q, Liu, C. Deposit date: 2023-04-14 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structures of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus To Be Published
8J2E	Structure of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus, mutant N940V/K1106W/S1114R in complex with NADP+ and malonate Descriptor: MALONIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase SDR Authors: Ma, Q, Liu, C. Deposit date: 2023-04-14 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (2.12 Å) Cite: Structures of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus To Be Published
8J2B	Structure of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus, in complex with NADP+ and malonate Descriptor: MALONIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase SDR Authors: Ma, Q, Liu, C. Deposit date: 2023-04-14 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (2.13 Å) Cite: Structures of the C-terminal subenzyme of the malonyl-CoA reductase from Chloroflexus aurantiacus To Be Published
6RNV	The crystal structure of Thermosynechococcus elongatus protochlorophyllide oxidoreductase (POR) Descriptor: CHLORIDE ION, Thermosynechococcus elongatus protochlorophyllide oxidoreductase (POR) Authors: Levy, C.W. Deposit date: 2019-05-09 Release date: 2019-10-30 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.27 Å) Cite: Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis. Nature, 574, 2019
6R46	Crystal structure of LPOR (Thermosynechococcus elongatus) complexed with NADP+ at 2.5A resolution Descriptor: CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH-protochlorophyllide oxidoreductase, ... Authors: Zhou, A, Feng, L. Deposit date: 2019-03-22 Release date: 2019-10-30 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis. Nature, 574, 2019
6RNW	The crystal structure of Thermosynechococcus elongatus protochlorophyllide oxidoreductase (POR) in complex with NADP. Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH-protochlorophyllide oxidoreductase Authors: Levy, C.W. Deposit date: 2019-05-09 Release date: 2019-10-30 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.92 Å) Cite: Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis. Nature, 574, 2019
6UHX	Crystal structure of YIR035C short chain dehydrogenases/reductase from Saccharomyces cerevisiae Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Uncharacterized oxidoreductase YIR035C Authors: Stogios, P.J, Skarina, T, Chen, C, Kagan, O, Iakounine, A, Savchenko, A. Deposit date: 2019-09-29 Release date: 2020-08-05 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Crystal structure of YIR035C short chain dehydrogenases/reductase from Saccharomyces cerevisiae To Be Published
4O5O	X-ray Crystal Structure of a 3-hydroxyacyl-CoA dehydrogenase from Brucella suis Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyacyl-CoA dehydrogenase, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2013-12-19 Release date: 2014-01-01 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.4 Å) Cite: X-ray Crystal Structure of a 3-hydroxyacyl-CoA dehydrogenase from Brucella suis TO BE PUBLISHED
7E24	Crystal structure of SDR family NAD(P)-dependent oxidoreductase from Exiguobacterium Descriptor: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase Authors: Chen, L, Tang, J, Yuan, S. Deposit date: 2021-02-04 Release date: 2021-09-29 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.7203 Å) Cite: Structure-guided evolution of a ketoreductase forefficient and stereoselective bioreduction of bulkyalpha-aminobeta-keto esters Catalysis Science And Technology, 2021
7E28	Crystal structure of SDR family NAD(P)-dependent oxidoreductase from Exiguobacterium Descriptor: Oxidoreductase Authors: Chen, L, Tang, J, Yuan, S. Deposit date: 2021-02-05 Release date: 2021-09-29 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.83 Å) Cite: Structure-guided evolution of a ketoreductase forefficient and stereoselective bioreduction of bulkyalpha-aminobeta-keto esters Catalysis Science And Technology, 2021
7E6O	Crystal structure of polyol dehydrogenase from Paracoccus denitrificans Descriptor: Short-chain dehydrogenase/reductase SDR Authors: Sha, F, Zheng, Y.C. Deposit date: 2021-02-22 Release date: 2022-03-02 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of polyol dehydrogenase from Paracoccus denitrificans To Be Published
4N5M	Crystal structure of (R)-3-hydroxybutyryl-CoA dehydrogenase from Ralstonia eutropha in complexed with acetoacetyl-CoA Descriptor: ACETOACETYL-COENZYME A, Acetoacetyl-CoA reductase, GLYCEROL Authors: Kim, J.-E, Kim, S, Kim, K.-J. Deposit date: 2013-10-10 Release date: 2013-12-11 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.34 Å) Cite: Crystal structure of (R)-3-hydroxybutyryl-CoA dehydrogenase PhaB from Ralstonia eutropha Biochem.Biophys.Res.Commun., 443, 2014
4N5L	Crystal structure of (R)-3-hydroxybutyryl-CoA dehydrogenase from Ralstonia eutropha Descriptor: Acetoacetyl-CoA reductase Authors: Kim, J.-E, Kim, S, Kim, K.-J. Deposit date: 2013-10-10 Release date: 2013-12-11 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structure of (R)-3-hydroxybutyryl-CoA dehydrogenase PhaB from Ralstonia eutropha Biochem.Biophys.Res.Commun., 443, 2014
4NMH	11-beta-HSD1 in complex with a 3,3-Di-methyl-azetidin-2-one Descriptor: (4S)-4-(2-methoxyphenyl)-3,3-dimethyl-1-[3-(methylsulfonyl)phenyl]azetidin-2-one, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: McCoull, W, Augustin, M, Blake, C, Ertan, A, Kilgour, E.K, Krapp, S, Moore, J.E, Newcombe, N.J, Packer, M.J, Rees, A, Revill, J, Scott, J.S, Selmi, N, Gerhardt, S, Ogg, D.J, Steinbacher, S, Whittamore, P.R.O. Deposit date: 2013-11-15 Release date: 2014-03-26 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Identification and optimisation of 3,3-dimethyl-azetidin-2-ones as potent and selective inhibitors of 11 beta-hydroxysteroid dehydrogenase type 1 (11-beta-HSD1) TO BE PUBLISHED
4N5N	Crystal structure of (R)-3-hydroxybutyryl-CoA dehydrogenase from Ralstonia eutropha in complexed with NADP Descriptor: Acetoacetyl-CoA reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Kim, J.-E, Kim, S, Kim, K.-J. Deposit date: 2013-10-10 Release date: 2013-12-11 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of (R)-3-hydroxybutyryl-CoA dehydrogenase PhaB from Ralstonia eutropha Biochem.Biophys.Res.Commun., 443, 2014
2NWQ	Short chain dehydrogenase from Pseudomonas aeruginosa Descriptor: Probable short-chain dehydrogenase, SULFATE ION Authors: McGrath, T.E, Kimber, M.S, Beattie, B, Thambipillai, D, Dharamsi, A, Virag, C, Nethery-Brokx, K, Edwards, A.M, Pai, E.F, Chirgadze, N.Y. Deposit date: 2006-11-16 Release date: 2006-11-28 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Short chain dehydrogenase from Pseudomonas aeruginosa To be Published
7ENY	Crystal structure of hydroxysteroid dehydrogenase from Escherichia coli Descriptor: 7alpha-hydroxysteroid dehydrogenase Authors: Kim, K.-H, Lee, C.W, Pardhe, D.P, Hwang, J, Do, H, Lee, Y.M, Lee, J.H, Oh, T.-J. Deposit date: 2021-04-21 Release date: 2021-07-14 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.703 Å) Cite: Crystal structure of an apo 7 alpha-hydroxysteroid dehydrogenase reveals key structural changes induced by substrate and co-factor binding. J.Steroid Biochem.Mol.Biol., 212, 2021
4P38	Human 11beta-Hydroxysteroid Dehydrogenase Type 1 in complex with AZD8329 Descriptor: 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic acid, CHLORIDE ION, Corticosteroid 11-beta-dehydrogenase isozyme 1, ... Authors: Ogg, D, Hargreaves, D, Gerhardt, S. Deposit date: 2014-03-06 Release date: 2014-04-30 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Novel acidic 11 beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1) inhibitor with reduced acyl glucuronide liability: the discovery of 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic acid (AZD8329). J.Med.Chem., 55, 2012
2O23	The structure of wild-type human HADH2 (17beta-hydroxysteroid dehydrogenase type 10) bound to NAD+ at 1.2 A Descriptor: GLYCEROL, HADH2 protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Kavanagh, K.L, Shafqat, N, Scholer, K, Debreczeni, J, Zschocke, J, von Delft, F, Weigelt, J, Arrowsmith, C, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) Deposit date: 2006-11-29 Release date: 2006-12-12 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.2 Å) Cite: The structure of wild-type human HADH2 (17beta-hydroxysteroid dehydrogenase type 10) bound to NAD+ at 1.2 A To be Published

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