2Q2E
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2NUP
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2NXN
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![BU of 2nxn by Molmil](/molmil-images/mine/2nxn) | T. thermophilus ribosomal protein L11 methyltransferase (PrmA) in complex with ribosomal protein L11 | Descriptor: | 50S ribosomal protein L11, Ribosomal protein L11 methyltransferase | Authors: | Demirci, H, Gregory, S.T, Dahlberg, A.E, Jogl, G. | Deposit date: | 2006-11-17 | Release date: | 2006-12-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Recognition of ribosomal protein L11 by the protein trimethyltransferase PrmA. Embo J., 26, 2007
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2NVQ
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![BU of 2nvq by Molmil](/molmil-images/mine/2nvq) | RNA Polymerase II Elongation Complex in 150 mM Mg+2 with 2'dUTP | Descriptor: | 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ... | Authors: | Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. | Deposit date: | 2006-11-13 | Release date: | 2006-12-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis Cell(Cambridge,Mass.), 127, 2006
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2NXE
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![BU of 2nxe by Molmil](/molmil-images/mine/2nxe) | T. thermophilus ribosomal protein L11 methyltransferase (PrmA) in complex with S-Adenosyl-L-Methionine | Descriptor: | Ribosomal protein L11 methyltransferase, S-ADENOSYLMETHIONINE | Authors: | Demirci, H, Gregory, S.T, Dahlberg, A.E, Jogl, G. | Deposit date: | 2006-11-17 | Release date: | 2006-12-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Recognition of ribosomal protein L11 by the protein trimethyltransferase PrmA. Embo J., 26, 2007
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2OCV
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![BU of 2ocv by Molmil](/molmil-images/mine/2ocv) | Structural basis of Na+ activation mimicry in murine thrombin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Thrombin | Authors: | Marino, F, Chen, Z, Ergenekan, C.E, Bush, L.A, Mathews, F.S, Di Cera, E. | Deposit date: | 2006-12-21 | Release date: | 2007-04-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of na+ activation mimicry in murine thrombin. J.Biol.Chem., 282, 2007
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2QH6
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![BU of 2qh6 by Molmil](/molmil-images/mine/2qh6) | Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Complexed with an Oxabicyclic diarylethylene Compound | Descriptor: | DIETHYL (1R,2S,3R,4S)-5,6-BIS(4-HYDROXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLATE, Estrogen receptor, Nuclear receptor coactivator 2 | Authors: | Nettles, K.W, Bruning, J.B, Nowak, J, Sharma, S.K, Hahm, J.B, Shi, Y, Kulp, K, Hochberg, R.B, Zhou, H, Katzenellenbogen, J.A, Katzenellenbogen, B.S, Kim, Y, Joachmiak, A, Greene, G.L. | Deposit date: | 2007-06-29 | Release date: | 2008-03-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses Nat.Chem.Biol., 4, 2008
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2OL3
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![BU of 2ol3 by Molmil](/molmil-images/mine/2ol3) | crystal structure of BM3.3 ScFV TCR in complex with PBM8-H-2KBM8 MHC class I molecule | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALLOGENEIC H-2KBM8 MHC CLASS I MOLECULE, BM3.3 T-CELL RECEPTOR ALPHA-CHAIN, ... | Authors: | Mazza, C, Auphan-Anezin, N, Gregoire, C, Guimezanes, A, Kellenberger, C, Roussel, A, Kearney, A, Van der Merwe, P.A, Schmitt-Verhulst, A.M, Malissen, B. | Deposit date: | 2007-01-18 | Release date: | 2007-04-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | How much can a T-cell antigen receptor adapt to structurally distinct antigenic peptides? Embo J., 26, 2007
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2ON9
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2ONX
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![BU of 2onx by Molmil](/molmil-images/mine/2onx) | NNQQ peptide corresponding to residues 8-11 of yeast prion sup35 (alternate crystal form) | Descriptor: | peptide corresponding to residues 8-11 of yeast prion sup35 | Authors: | Sawaya, M.R, Sambashivan, S, Nelson, R, Ivanova, M, Sievers, S.A, Apostol, M.I, Thompson, M.J, Balbirnie, M, Wiltzius, J.J, McFarlane, H, Madsen, A.O, Riekel, C, Eisenberg, D. | Deposit date: | 2007-01-24 | Release date: | 2007-02-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Atomic structures of amyloid cross-beta spines reveal varied steric zippers. Nature, 447, 2007
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2OZF
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![BU of 2ozf by Molmil](/molmil-images/mine/2ozf) | The crystal structure of the 2nd PDZ domain of the human NHERF-1 (SLC9A3R1) | Descriptor: | Ezrin-radixin-moesin-binding phosphoprotein 50 | Authors: | Phillips, C, Papagrigoriou, E, Gileadi, C, Fedorov, O, Elkins, J, Berridge, G, Turnbull, A.P, Gileadi, O, Schoch, G, Smee, C, Bray, J, Savitsky, P, Uppenberg, J, von Delft, F, Gorrec, F, Umeano, C, Salah, E, Colebrook, S, Weigelt, J, Arrowsmith, C.H, Edwards, A, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC) | Deposit date: | 2007-02-26 | Release date: | 2007-03-13 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The crystal structure of the 2nd PDZ domain of the human NHERF-1 (SLC9A3R1) To be Published
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2OKZ
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2PQC
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![BU of 2pqc by Molmil](/molmil-images/mine/2pqc) | CP4 EPSPS liganded with (R)-phosphonate tetrahedral reaction intermediate analog | Descriptor: | 3-phosphoshikimate 1-carboxyvinyltransferase, [3R-[3A,4A,5B(R*)]]-5-(1-CARBOXY-1-PHOSPHONOETHOXY)-4-HYDROXY-3-(PHOSPHONOOXY)-1-CYCLOHEXENE-1-CARBOXYLIC ACID | Authors: | Healy-Fried, M.L, Funke, T, Han, H, Schonbrunn, E. | Deposit date: | 2007-05-01 | Release date: | 2008-03-11 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Differential inhibition of class I and class II 5-enolpyruvylshikimate-3-phosphate synthases by tetrahedral reaction intermediate analogues. Biochemistry, 46, 2007
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2Q17
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![BU of 2q17 by Molmil](/molmil-images/mine/2q17) | Formylglycine Generating Enzyme from Streptomyces coelicolor | Descriptor: | CALCIUM ION, formylglycine generating enzyme | Authors: | Carlson, B.L, Ballister, E.R, Skordalakes, E, King, D.S, Breidenbach, M.A, Gilmore, S.A, Berger, J.M, Bertozzi, C.R. | Deposit date: | 2007-05-23 | Release date: | 2008-04-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Function and structure of a prokaryotic formylglycine-generating enzyme. J.Biol.Chem., 283, 2008
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2PZY
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![BU of 2pzy by Molmil](/molmil-images/mine/2pzy) | Structure of MK2 Complexed with Compound 76 | Descriptor: | (4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDE, MAP kinase-activated protein kinase 2, STAUROSPORINE | Authors: | White, A, Wu, J.P, Wang, J, Abeywardane, A, Andersen, D, Emmanuel, M, Gautschi, E, Goldberg, D.R, Kashem, M.A, Lukas, S, Mao, W, Martin, L, Morwick, T, Moss, N, Pargellis, C, Patel, U.R, Patnaude, L, Peet, G.W, Skow, D, Snow, R.J, Ward, Y, Werneburg, B. | Deposit date: | 2007-05-18 | Release date: | 2007-07-31 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The discovery of carboline analogs as potent MAPKAP-K2 inhibitors Bioorg.Med.Chem.Lett., 17, 2007
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2PQB
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![BU of 2pqb by Molmil](/molmil-images/mine/2pqb) | CP4 EPSPS liganded with (R)-difluoromethyl tetrahedral intermediate analog | Descriptor: | (3R,4S,5R)-5-[(1R)-1-CARBOXY-2,2-DIFLUORO-1-(PHOSPHONOOXY)ETHOXY]-4-HYDROXY-3-(PHOSPHONOOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC ACID, 3-phosphoshikimate 1-carboxyvinyltransferase | Authors: | Healy-Fried, M.L, Funke, T, Han, H, Schonbrunn, E. | Deposit date: | 2007-05-01 | Release date: | 2008-03-11 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Differential inhibition of class I and class II 5-enolpyruvylshikimate-3-phosphate synthases by tetrahedral reaction intermediate analogues. Biochemistry, 46, 2007
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2QVL
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2QXM
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![BU of 2qxm by Molmil](/molmil-images/mine/2qxm) | Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Complexed to Burned Meat Compound PhIP | Descriptor: | 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE, Estrogen receptor, Nuclear receptor coactivator 2 | Authors: | Nettles, K.W, Bruning, J.B, Gil, G, Nowak, J, Sharma, S.K, Hahm, J.B, Shi, Y, Kulp, K, Hochberg, R.B, Zhou, H, Katzenellenbogen, J.A, Katzenellenbogen, B.S, Kim, Y, Joachmiak, A, Greene, G.L. | Deposit date: | 2007-08-12 | Release date: | 2008-03-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses Nat.Chem.Biol., 4, 2008
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2QNK
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![BU of 2qnk by Molmil](/molmil-images/mine/2qnk) | Crystal structure of human 3-hydroxyanthranilate 3,4-dioxygenase | Descriptor: | 3-hydroxyanthranilate 3,4-dioxygenase, NICKEL (II) ION, PHOSPHATE ION | Authors: | Bitto, E, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2007-07-18 | Release date: | 2007-08-14 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal Structure of Human 3-hydroxyanthranilate 3,4-dioxygenase. to be published
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2NVX
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![BU of 2nvx by Molmil](/molmil-images/mine/2nvx) | RNA polymerase II elongation complex in 5 mM Mg+2 with 2'-dUTP | Descriptor: | 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ... | Authors: | Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. | Deposit date: | 2006-11-13 | Release date: | 2006-12-19 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis Cell(Cambridge,Mass.), 127, 2006
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2O39
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![BU of 2o39 by Molmil](/molmil-images/mine/2o39) | Human Adenovirus type 11 knob in complex with domains SCR1 and SCR2 of CD46 (membrane cofactor protein, MCP) | Descriptor: | CALCIUM ION, Fiber protein, Membrane cofactor protein, ... | Authors: | Persson, D.B, Reiter, D.M, Arnberg, N, Stehle, T. | Deposit date: | 2006-12-01 | Release date: | 2007-01-09 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Adenovirus type 11 binding alters the conformation of its receptor CD46. Nat.Struct.Mol.Biol., 14, 2007
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2OMQ
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2QGT
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![BU of 2qgt by Molmil](/molmil-images/mine/2qgt) | Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Complexed to an Ether Estradiol Compound | Descriptor: | (9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL, Estrogen receptor, Nuclear receptor coactivator 2 | Authors: | Nettles, K.W, Bruning, J.B, Nowak, J, Sharma, S.K, Hahm, J.B, Shi, Y, Kulp, K, Hochberg, R.B, Zhou, H, Katzenellenbogen, J.A, Katzenellenbogen, B.S, Kim, Y, Joachmiak, A, Greene, G.L. | Deposit date: | 2007-06-29 | Release date: | 2008-03-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses Nat.Chem.Biol., 4, 2008
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4OQ7
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2QA8
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![BU of 2qa8 by Molmil](/molmil-images/mine/2qa8) | Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Mutant 537S Complexed with Genistein | Descriptor: | Estrogen receptor, GENISTEIN, nuclear receptor coactivator 2 | Authors: | Nettles, K.W, Bruning, J.B, Nowak, J, Sharma, S.K, Hahm, J.B, Shi, Y, Kulp, K, Hochberg, R.B, Zhou, H, Katzenellenbogen, J.A, Katzenellenbogen, B.S, Kim, Y, Joachmiak, A, Greene, G.L. | Deposit date: | 2007-06-14 | Release date: | 2008-03-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses Nat.Chem.Biol., 4, 2008
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