1I4H
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![BU of 1i4h by Molmil](/molmil-images/mine/1i4h) | Crystal structure of Zn2+ soaked Staphylococcal enterotoxin A mutant H187A | Descriptor: | ENTEROTOXIN TYPE A, ZINC ION | Authors: | Hakansson, M, Antonsson, P, Bjork, P, Svensson, L.A. | Deposit date: | 2001-02-21 | Release date: | 2001-02-28 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Cooperative zinc binding in a staphylococcal enterotoxin A mutant mimics the SEA-MHC class II interaction J.Biol.Inorg.Chem., 6, 2001
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1I4G
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![BU of 1i4g by Molmil](/molmil-images/mine/1i4g) | Crystal structure of Staphylococcal enterotoxin A mutant H187A with reduced Zn2+ affinity | Descriptor: | ENTEROTOXIN TYPE A, SULFATE ION, ZINC ION | Authors: | Hakansson, M, Antonsson, P, Bjork, P, Svensson, L.A. | Deposit date: | 2001-02-21 | Release date: | 2001-02-28 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Cooperative zinc binding in a staphylococcal enterotoxin A mutant mimics the SEA-MHC class II interaction J.Biol.Inorg.Chem., 6, 2001
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1L0Y
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![BU of 1l0y by Molmil](/molmil-images/mine/1l0y) | T cell receptor beta chain complexed with superantigen SpeA soaked with zinc | Descriptor: | 14.3.d T cell receptor beta chain, Exotoxin type A, GLYCEROL, ... | Authors: | Li, H, Sundberg, E.J, Mariuzza, R.A. | Deposit date: | 2002-02-14 | Release date: | 2002-04-03 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes. Structure, 10, 2002
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1I4X
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![BU of 1i4x by Molmil](/molmil-images/mine/1i4x) | |
1L0X
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![BU of 1l0x by Molmil](/molmil-images/mine/1l0x) | |
1JCK
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![BU of 1jck by Molmil](/molmil-images/mine/1jck) | |
1CQV
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![BU of 1cqv by Molmil](/molmil-images/mine/1cqv) | |
1CK1
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![BU of 1ck1 by Molmil](/molmil-images/mine/1ck1) | |
1B1Z
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![BU of 1b1z by Molmil](/molmil-images/mine/1b1z) | STREPTOCOCCAL PYROGENIC EXOTOXIN A1 | Descriptor: | PROTEIN (TOXIN) | Authors: | Papageorgiou, A.C, Acharya, K.R. | Deposit date: | 1998-11-24 | Release date: | 1999-11-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Structural basis for the recognition of superantigen streptococcal pyrogenic exotoxin A (SpeA1) by MHC class II molecules and T-cell receptors. EMBO J., 18, 1999
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1DYQ
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![BU of 1dyq by Molmil](/molmil-images/mine/1dyq) | STAPHYLOCOCCAL ENTEROTOXIN A MUTANT VACCINE | Descriptor: | Enterotoxin type A, SULFATE ION, ZINC ION | Authors: | Krupka, H.I, Segelke, B.W, Rupp, B. | Deposit date: | 2000-02-05 | Release date: | 2001-03-19 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural Basis for Abrogated Binding between Staphylococcal Enterotoxin a Superantigen Vaccine and Mhc-II? Protein Sci., 11, 2002
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1ENF
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![BU of 1enf by Molmil](/molmil-images/mine/1enf) | CRYSTAL STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN H DETERMINED TO 1.69 A RESOLUTION | Descriptor: | ENTEROTOXIN H, SULFATE ION | Authors: | Hakansson, M, Petersson, K, Nilsson, H, Forsberg, G, Bjork, P, Antonsson, P, Svensson, A. | Deposit date: | 2000-03-21 | Release date: | 2000-04-19 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | The crystal structure of staphylococcal enterotoxin H: implications for binding properties to MHC class II and TcR molecules. J.Mol.Biol., 302, 2000
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1ET9
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![BU of 1et9 by Molmil](/molmil-images/mine/1et9) | CRYSTAL STRUCTURE OF THE SUPERANTIGEN SPE-H FROM STREPTOCOCCUS PYOGENES | Descriptor: | SUPERANTIGEN SPE-H | Authors: | Arcus, V.L, Proft, T, Sigrell, J.A, Baker, H.M, Fraser, J.D, Baker, E.N. | Deposit date: | 2000-04-12 | Release date: | 2000-04-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Conservation and variation in superantigen structure and activity highlighted by the three-dimensional structures of two new superantigens from Streptococcus pyogenes. J.Mol.Biol., 299, 2000
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1ESF
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![BU of 1esf by Molmil](/molmil-images/mine/1esf) | STAPHYLOCOCCAL ENTEROTOXIN A | Descriptor: | CADMIUM ION, STAPHYLOCOCCAL ENTEROTOXIN A | Authors: | Schad, E.M, Svensson, L.A. | Deposit date: | 1995-05-25 | Release date: | 1996-07-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the superantigen staphylococcal enterotoxin type A. EMBO J., 14, 1995
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1AN8
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![BU of 1an8 by Molmil](/molmil-images/mine/1an8) | CRYSTAL STRUCTURE OF THE STREPTOCOCCAL SUPERANTIGEN SPE-C | Descriptor: | STREPTOCOCCAL PYROGENIC EXOTOXIN C | Authors: | Roussel, A, Baker, E.N. | Deposit date: | 1997-06-27 | Release date: | 1998-04-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the streptococcal superantigen SPE-C: dimerization and zinc binding suggest a novel mode of interaction with MHC class II molecules. Nat.Struct.Biol., 4, 1997
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1EU4
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![BU of 1eu4 by Molmil](/molmil-images/mine/1eu4) | CRYSTAL STRUCTURE OF THE SUPERANTIGEN SPE-H (ZINC BOUND) FROM STREPTOCOCCUS PYOGENES | Descriptor: | SUPERANTIGEN SPE-H, ZINC ION | Authors: | Arcus, V.L, Proft, T, Sigrell, J.A, Baker, H.M, Fraser, J.D, Baker, E.N. | Deposit date: | 2000-04-13 | Release date: | 2000-04-26 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Conservation and variation in superantigen structure and activity highlighted by the three-dimensional structures of two new superantigens from Streptococcus pyogenes. J.Mol.Biol., 299, 2000
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1BXT
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![BU of 1bxt by Molmil](/molmil-images/mine/1bxt) | |
1ET6
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![BU of 1et6 by Molmil](/molmil-images/mine/1et6) | CRYSTAL STRUCTURE OF THE SUPERANTIGEN SMEZ-2 FROM STREPTOCOCCUS PYOGENES | Descriptor: | SUPERANTIGEN SMEZ-2 | Authors: | Arcus, V.L, Proft, T, Sigrell, J.A, Baker, H.M, Fraser, J.D, Baker, E.N. | Deposit date: | 2000-04-12 | Release date: | 2000-05-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Conservation and variation in superantigen structure and activity highlighted by the three-dimensional structures of two new superantigens from Streptococcus pyogenes. J.Mol.Biol., 299, 2000
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1EU3
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![BU of 1eu3 by Molmil](/molmil-images/mine/1eu3) | CRYSTAL STRUCTURE OF THE SUPERANTIGEN SMEZ-2 (ZINC BOUND) FROM STREPTOCOCCUS PYOGENES | Descriptor: | PHOSPHATE ION, POTASSIUM ION, SUPERANTIGEN SMEZ-2, ... | Authors: | Arcus, V.L, Proft, T, Sigrell, J.A, Baker, H.M, Fraser, J.D, Baker, E.N. | Deposit date: | 2000-04-13 | Release date: | 2000-04-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Conservation and variation in superantigen structure and activity highlighted by the three-dimensional structures of two new superantigens from Streptococcus pyogenes. J.Mol.Biol., 299, 2000
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1EWC
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![BU of 1ewc by Molmil](/molmil-images/mine/1ewc) | CRYSTAL STRUCTURE OF ZN2+ LOADED STAPHYLOCOCCAL ENTEROTOXIN H | Descriptor: | ENTEROTOXIN H, ZINC ION | Authors: | Hakansson, M, Petersson, K, Nilsson, H, Forsberg, G, Bjork, P, Antonsson, P, Svensson, A. | Deposit date: | 2000-04-25 | Release date: | 2000-05-31 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The crystal structure of staphylococcal enterotoxin H: implications for binding properties to MHC class II and TcR molecules. J.Mol.Biol., 302, 2000
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4C56
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![BU of 4c56 by Molmil](/molmil-images/mine/4c56) | X-ray structure of the complex between staphylococcal enterotoxin B, T cell receptor and major histocompatibility complex class II | Descriptor: | ENTEROTOXIN B, GLYCEROL, HEMAGGLUTININ, ... | Authors: | Rodstrom, K.E.J, Elbing, K, Lindkvist-Petersson, K. | Deposit date: | 2013-09-10 | Release date: | 2014-07-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of the Superantigen Staphylococcal Enterotoxin B in Complex with Tcr and Peptide-Mhc Demonstrates Absence of Tcr-Peptide Contacts. J.Immunol., 193, 2014
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2SEB
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![BU of 2seb by Molmil](/molmil-images/mine/2seb) | X-RAY CRYSTAL STRUCTURE OF HLA-DR4 COMPLEXED WITH A PEPTIDE FROM HUMAN COLLAGEN II | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENTEROTOXIN TYPE B, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, ... | Authors: | Dessen, A, Lawrence, C.M, Cupo, S, Zaller, D.M, Wiley, D.C. | Deposit date: | 1997-10-16 | Release date: | 1998-01-28 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | X-ray crystal structure of HLA-DR4 (DRA*0101, DRB1*0401) complexed with a peptide from human collagen II. Immunity, 7, 1997
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1PYW
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![BU of 1pyw by Molmil](/molmil-images/mine/1pyw) | Human class II MHC protein HLA-DR1 bound to a designed peptide related to influenza virus hemagglutinin, FVKQNA(MAA)AL, in complex with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2) | Descriptor: | 9-residue influenza virus hemagglutinin related peptide FVKQNA(MAA)AL, Enterotoxin type C-3, HLA class II histocompatibility antigen, ... | Authors: | Zavala-Ruiz, Z, Sundberg, E.J, Stone, J.D, DeOliveira, D.B, Chan, I.C, Svendsen, J, Mariuzza, R.A, Stern, L.J. | Deposit date: | 2003-07-09 | Release date: | 2003-12-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Exploration of the P6/P7 region of the peptide-binding site of the human class II Major Histocompatability Complex Protein HLA-DR1 J.Biol.Chem., 278, 2003
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2IPK
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![BU of 2ipk by Molmil](/molmil-images/mine/2ipk) | Crystal Structure of the MHC Class II Molecule HLA-DR1 in Complex with the Fluorogenic Peptide, AcPKXVKQNTLKLAT (X=3-[5-(dimethylamino)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]-L-alanine) and the Superantigen, SEC3 Variant 3B2 | Descriptor: | Enterotoxin type C-3, HA related Fluorogenic Peptide, AcPKXVKQNTLKLAT (X=3-[5-(dimethylamino)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]-L-alanine), ... | Authors: | Nguyen, T.T, Stern, L.J. | Deposit date: | 2006-10-12 | Release date: | 2007-03-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells. Nat.Chem.Biol., 3, 2007
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2G9H
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![BU of 2g9h by Molmil](/molmil-images/mine/2g9h) | Crystal Structure of Staphylococcal Enterotoxin I (SEI) in Complex with a Human MHC class II Molecule | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HLA class II histocompatibility antigen, ... | Authors: | Fernandez, M.M, Guan, R, Malchiodi, E.L, Mariuzza, R.A. | Deposit date: | 2006-03-06 | Release date: | 2006-07-11 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of staphylococcal enterotoxin I (SEI) in complex with a human major histocompatibility complex class II molecule. J.Biol.Chem., 281, 2006
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2XN9
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![BU of 2xn9 by Molmil](/molmil-images/mine/2xn9) | Crystal structure of the ternary complex between human T cell receptor, staphylococcal enterotoxin H and human major histocompatibility complex class II | Descriptor: | ENTEROTOXIN H, GLYCEROL, HEMAGGLUTININ, ... | Authors: | Saline, M, Rodstrom, K.E.J, Fischer, G, Orekhov, V.Y, Karlsson, B.G, Lindkvist-Petersson, K. | Deposit date: | 2010-07-31 | Release date: | 2010-11-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The Structure of Superantigen Complexed with Tcr and Mhc Reveals Novel Insights Into Superantigenic T Cell Activation. Nat.Commun., 1, 2010
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