1II6
| Crystal Structure of the Mitotic Kinesin Eg5 in Complex with Mg-ADP. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, KINESIN-RELATED MOTOR PROTEIN Eg5, MAGNESIUM ION, ... | Authors: | Turner, J, Anderson, R, Guo, J, Beraud, C, Sakowicz, R, Fletterick, R. | Deposit date: | 2001-04-20 | Release date: | 2001-07-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of the mitotic spindle kinesin Eg5 reveals a novel conformation of the neck-linker. J.Biol.Chem., 276, 2001
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7A40
| Nucleotide-free OSM-3 kinesin motor domain | Descriptor: | GLYCEROL, Osmotic avoidance abnormal protein 3, SULFATE ION | Authors: | Varela, F.P, Menetrey, J, Gigant, B. | Deposit date: | 2020-08-19 | Release date: | 2021-02-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.297 Å) | Cite: | Structural snapshots of the kinesin-2 OSM-3 along its nucleotide cycle: implications for the ATP hydrolysis mechanism. Febs Open Bio, 11, 2021
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7A5E
| OSM-3 kinesin motor domain complexed with Mg.AMPPNP | Descriptor: | GLYCEROL, MAGNESIUM ION, Osmotic avoidance abnormal protein 3, ... | Authors: | Varela, F.P, Menetrey, J, Gigant, B. | Deposit date: | 2020-08-21 | Release date: | 2021-02-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.904 Å) | Cite: | Structural snapshots of the kinesin-2 OSM-3 along its nucleotide cycle: implications for the ATP hydrolysis mechanism. Febs Open Bio, 11, 2021
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6M4I
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6NJE
| Crystal structure of the motor domain of human kinesin family member 22 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Kinesin-like protein KIF22, ... | Authors: | Walker, B.C, Zhu, H, Tempel, W, Arrowsmith, C.H, Edwards, A.M, Park, H, Cochran, J.C, Structural Genomics Consortium (SGC) | Deposit date: | 2019-01-03 | Release date: | 2019-01-16 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the motor domain of human kinesin family member 22 To Be Published
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7A3Z
| OSM-3 kinesin motor domain complexed with Mg.ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Osmotic avoidance abnormal protein 3 | Authors: | Varela, F.P, Menetrey, J, Gigant, B. | Deposit date: | 2020-08-19 | Release date: | 2021-02-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.095 Å) | Cite: | Structural snapshots of the kinesin-2 OSM-3 along its nucleotide cycle: implications for the ATP hydrolysis mechanism. Febs Open Bio, 11, 2021
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1I5S
| CRYSTAL STRUCTURE OF THE KIF1A MOTOR DOMAIN COMPLEXED WITH MG-ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KIF1A, MAGNESIUM ION | Authors: | Kikkawa, M, Sablin, E.P, Okada, Y, Yajima, H, Fletterick, R.J, Hirokawa, N. | Deposit date: | 2001-02-28 | Release date: | 2001-05-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Switch-based mechanism of kinesin motors Nature, 411, 2001
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1I6I
| CRYSTAL STRUCTURE OF THE KIF1A MOTOR DOMAIN COMPLEXED WITH MG-AMPPCP | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, KINESIN-LIKE PROTEIN KIF1A, MAGNESIUM ION, ... | Authors: | Kikkawa, M, Sablin, E.P, Okada, Y, Yajima, H, Fletterick, R.J, Hirokawa, N. | Deposit date: | 2001-03-02 | Release date: | 2001-05-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Switch-based mechanism of kinesin motors Nature, 411, 2001
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1MKJ
| Human Kinesin Motor Domain With Docked Neck Linker | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, KINESIN HEAVY CHAIN, MAGNESIUM ION, ... | Authors: | Sindelar, C.V, Budny, M.J, Rice, S, Naber, N, Fletterick, R, Cooke, R. | Deposit date: | 2002-08-29 | Release date: | 2002-10-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Two conformations in the human kinesin power stroke defined by X-ray crystallography and EPR spectroscopy. Nat.Struct.Biol., 9, 2002
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6TLE
| Human Eg5 motor domain mutant E344K | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, MAGNESIUM ION, ... | Authors: | Garcia-Saez, I, Skoufias, D.A. | Deposit date: | 2019-12-02 | Release date: | 2021-06-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Human Eg5 motor domain mutant E344K To Be Published
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6TRL
| Human Eg5 motor domain mutant Y82F | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, Kinesin-like protein KIF11, ... | Authors: | Garcia-Saez, I, Skoufias, D.A. | Deposit date: | 2019-12-19 | Release date: | 2021-06-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Human Eg5 motor domain mutant Y82F To Be Published
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2OWM
| Motor domain of Neurospora crassa kinesin-3 (NcKin3) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Related to KINESIN-LIKE PROTEIN KIF1C | Authors: | Marx, A, Muller, J, Mandelkow, E.-M, Woehlke, G, Mandelkow, E. | Deposit date: | 2007-02-16 | Release date: | 2008-01-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | X-ray Structure and Microtubule Interaction of the Motor Domain of Neurospora crassa NcKin3, a Kinesin with Unusual Processivity Biochemistry, 47, 2008
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2Q2Z
| Crystal Structure of KSP in Complex with Inhibitor 22 | Descriptor: | 1-[(4R)-4-[3-(4-ACETYLPIPERAZIN-1-YL)PROPYL]-1-(2-FLUORO-5-METHYLPHENYL)-4-PHENYL-4,5-DIHYDRO-1H-PYRAZOL-3-YL]ETHANONE, ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, ... | Authors: | Yan, Y. | Deposit date: | 2007-05-29 | Release date: | 2007-09-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP. Bioorg.Med.Chem.Lett., 17, 2007
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2PG2
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2NCD
| NCD (NON-CLARET DISJUNCTIONAL) DIMER FROM D. MELANOGASTER | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, PROTEIN (Kinesin motor NCD), SULFATE ION | Authors: | Sablin, E.P, Case, R.B, Dai, S.C, Hart, C.L, Ruby, A, Vale, R.D, Fletterick, R.J. | Deposit date: | 1999-06-04 | Release date: | 1999-06-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Direction determination in the minus-end-directed kinesin motor ncd. Nature, 395, 1998
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2Q2Y
| Crystal Structure of KSP in complex with Inhibitor 1 | Descriptor: | 1-{(3R,3AR)-3-[3-(4-ACETYLPIPERAZIN-1-YL)PROPYL]-8-FLUORO-3-PHENYL-3A,4-DIHYDRO-3H-PYRAZOLO[5,1-C][1,4]BENZOXAZIN-2-YL}ETHANONE, ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11, ... | Authors: | Yan, Y. | Deposit date: | 2007-05-29 | Release date: | 2007-09-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP. Bioorg.Med.Chem.Lett., 17, 2007
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2GRY
| Crystal structure of the human KIF2 motor domain in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF2, MAGNESIUM ION, ... | Authors: | Wang, J, Shen, Y, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2006-04-25 | Release date: | 2006-05-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal structure of the human KIF2 motor domain in complex with ADP to be published
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5GSY
| Kinesin-8 motor, KIF19A, in the nucleotide-free state complexed with GDP-taxol microtubule | Descriptor: | Kinesin-like protein KIF19 | Authors: | Morikawa, M, Nitta, R, Yajima, H, Shigematsu, H, Kikkawa, M, Hirokawa, N. | Deposit date: | 2016-08-17 | Release date: | 2016-09-28 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | Motility and microtubule depolymerization mechanisms of the Kinesin-8 motor, KIF19A Elife, 5, 2016
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7LFF
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7LXR
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2IEH
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5GSZ
| Crystal Structure of the KIF19A Motor Domain Complexed with Mg-ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF19, MAGNESIUM ION | Authors: | Wang, D, Nitta, R, Hirokawa, N. | Deposit date: | 2016-08-18 | Release date: | 2016-09-28 | Last modified: | 2020-02-26 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Motility and microtubule depolymerization mechanisms of the Kinesin-8 motor, KIF19A Elife, 5, 2016
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2HEH
| Crystal Structure of the KIF2C motor domain | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, KIF2C protein, MAGNESIUM ION, ... | Authors: | Wang, J, Shen, Y, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2006-06-21 | Release date: | 2006-07-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of the kif2c motor domain to be published
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5HLE
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2KIN
| KINESIN (MONOMERIC) FROM RATTUS NORVEGICUS | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, KINESIN, SULFATE ION | Authors: | Sack, S, Muller, J, Kozielski, F, Marx, A, Thormahlen, M, Biou, V, Mandelkow, E.-M, Brady, S.T, Mandelkow, E. | Deposit date: | 1997-04-28 | Release date: | 1998-04-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray structure of motor and neck domains from rat brain kinesin. Biochemistry, 36, 1997
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