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3K5M
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BU of 3k5m by Molmil
Crystal structure of E.coli Pol II-abasic DNA-ddGTP Lt(-2, 2) ternary complex
Descriptor: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*TP*CP*CP*TP*GP*(3DR)P*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ...
Authors:Yang, W, Wang, F.
Deposit date:2009-10-07
Release date:2010-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II.
Cell(Cambridge,Mass.), 139, 2009
3K59
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BU of 3k59 by Molmil
Crystal structure of E.coli Pol II-normal DNA-dCTP ternary complex
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*GP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ...
Authors:Yang, W, Wang, F.
Deposit date:2009-10-06
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II
Cell(Cambridge,Mass.), 139, 2009
3K57
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BU of 3k57 by Molmil
Crystal structure of E.coli Pol II-normal DNA-dATP ternary complex
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*G*TP*AP*TP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*G)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), ...
Authors:Yang, W, Wang, F.
Deposit date:2009-10-06
Release date:2010-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II
Cell(Cambridge,Mass.), 139, 2009
3MAQ
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BU of 3maq by Molmil
Crystal structure of E.coli Pol II-normal DNA-dGTP ternary complex
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*CP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ...
Authors:Yang, W, Wang, F.
Deposit date:2010-03-24
Release date:2010-04-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insight into translesion synthesis by DNA Pol II
Cell(Cambridge,Mass.), 139, 2009
6O85
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BU of 6o85 by Molmil
Electron cryo-microscopy of the eukaryotic translation initiation factor 2B bound to eukaryotic translation initiation factor 2 from Homo sapiens
Descriptor: 2-(4-chloranylphenoxy)-~{N}-[4-[2-(4-chloranylphenoxy)ethanoylamino]cyclohexyl]ethanamide, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, ...
Authors:Nguyen, H.C, Kenner, L.R, Frost, A.S.
Deposit date:2019-03-08
Release date:2019-05-15
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response.
Science, 364, 2019
6O7Y
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BU of 6o7y by Molmil
Trypanosoma cruzi EIF4E5 translation initiation factor in complex with cap-4
Descriptor: 2-amino-9-[(2R,3R,4S,5R)-5-({[(R)-{[(R)-{[(S)-({(2R,3R,4R,5R)-3-{[(R)-{[(2R,3R,4R,5R)-3-{[(S)-{[(2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-{[(S)-hydroxy{[(2R,3R,4R,5R)-3-hydroxy-4-methoxy-5-(3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl]methoxy}phosphoryl]oxy}-4-methoxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}-5-(6-amino-9H-purin-9-yl)-4-methoxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}-5-[6-(dimethylamino)-9H-purin-9-yl]-4-methoxytetrahydrofuran-2-yl}methoxy)(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxytetrahydrofuran-2-yl]-7-methyl-6-oxo-6,9-dihydro-3H-purin-7-ium, Putative Eukaryotic translation initiation factor 4E type 5, SULFATE ION
Authors:Guimaraes, B.G, Reolon, L.W.
Deposit date:2019-03-08
Release date:2019-05-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the Trypanosoma cruzi EIF4E5 translation factor homologue in complex with mRNA cap-4.
Nucleic Acids Res., 47, 2019
6O80
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BU of 6o80 by Molmil
Trypanosoma cruzi EIF4E5 translation initiation factor in complex with m7GTP
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Putative Eukaryotic translation initiation factor 4E type 5, SULFATE ION
Authors:Guimaraes, B.G, Reolon, L.W.
Deposit date:2019-03-08
Release date:2019-05-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the Trypanosoma cruzi EIF4E5 translation factor homologue in complex with mRNA cap-4.
Nucleic Acids Res., 47, 2019
6O7Z
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BU of 6o7z by Molmil
Trypanosoma cruzi EIF4E5 translation initiation factor in complex with cap-1
Descriptor: 2-amino-9-[(2R,3R,4S,5R)-5-({[(R)-{[(S)-{[(R)-({(2R,3R,4R,5R)-5-[6-(dimethylamino)-9H-purin-9-yl]-3-hydroxy-4-methoxytetrahydrofuran-2-yl}methoxy)(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxytetrahydrofuran-2-yl]-7-methyl-6-oxo-6,9-dihydro-1H-purin-7-ium, Putative Eukaryotic translation initiation factor 4E type 5, SULFATE ION
Authors:Guimaraes, B.G, Reolon, L.W.
Deposit date:2019-03-08
Release date:2019-05-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the Trypanosoma cruzi EIF4E5 translation factor homologue in complex with mRNA cap-4.
Nucleic Acids Res., 47, 2019
7GPB
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BU of 7gpb by Molmil
STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP
Descriptor: ADENOSINE MONOPHOSPHATE, GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Barford, D, Hu, S.-H, Johnson, L.N.
Deposit date:1990-11-13
Release date:1992-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP.
J.Mol.Biol., 218, 1991
6O81
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BU of 6o81 by Molmil
Electron cryo-microscopy of the eukaryotic translation initiation factor 2B bound to translation initiation factor 2 from Homo sapiens
Descriptor: 2-(4-chloranylphenoxy)-~{N}-[4-[2-(4-chloranylphenoxy)ethanoylamino]cyclohexyl]ethanamide, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, ...
Authors:Nguyen, H, Kenner, L, Frost, A.
Deposit date:2019-03-08
Release date:2019-05-15
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response.
Science, 364, 2019
6YAM
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BU of 6yam by Molmil
Mammalian 48S late-stage translation initiation complex (LS48S+eIF3 IC) with beta-globin mRNA
Descriptor: 18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein eS10, ...
Authors:Bochler, A, Simonetti, A, Guca, E, Hashem, Y.
Deposit date:2020-03-12
Release date:2020-04-08
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural Insights into the Mammalian Late-Stage Initiation Complexes.
Cell Rep, 31, 2020
4V7F
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BU of 4v7f by Molmil
Arx1 pre-60S particle.
Descriptor: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Leidig, C, Thoms, M, Holdermann, I, Bradatsch, B, Berninghausen, O, Bange, G, Sinning, I, Hurt, E, Beckmann, R.
Deposit date:2013-12-10
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:60S ribosome biogenesis requires rotation of the 5S ribonucleoprotein particle.
Nat Commun, 5, 2014
5LNK
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BU of 5lnk by Molmil
Entire ovine respiratory complex I
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 4'-PHOSPHOPANTETHEINE, ...
Authors:Fiedorczuk, K, Letts, J.A, Kaszuba, K, Sazanov, L.A.
Deposit date:2016-08-04
Release date:2016-11-23
Last modified:2021-06-02
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Atomic structure of the entire mammalian mitochondrial complex I.
Nature, 538, 2016
8PPL
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BU of 8ppl by Molmil
MERS-CoV Nsp1 bound to the human 43S pre-initiation complex
Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Schubert, K, Karousis, E.D, Ban, I, Lapointe, C.P, Leibundgut, M, Baeumlin, E, Kummerant, E, Scaiola, A, Schoenhut, T, Ziegelmueller, J, Puglisi, J.D, Muehlemann, O, Ban, N.
Deposit date:2023-07-07
Release date:2023-10-18
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Universal features of Nsp1-mediated translational shutdown by coronaviruses.
Mol.Cell, 83, 2023
1KN5
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BU of 1kn5 by Molmil
SOLUTION STRUCTURE OF ARID DOMAIN OF ADR6 FROM SACCHAROMYCES CEREVISIAE
Descriptor: Transcription regulatory protein ADR6
Authors:Tu, X, Wu, J, Xu, Y, Shi, Y.
Deposit date:2001-12-18
Release date:2002-07-17
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:1H, 13C and 15N resonance assignments and secondary structure of ADR6 DNA-binding domain.
J.Biomol.Nmr, 21, 2001
4V4B
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BU of 4v4b by Molmil
Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models for RNA and protein components into a 11.7 A cryo-EM map.
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S11, ...
Authors:Spahn, C.M, Gomez-Lorenzo, M.G, Grassucci, R.A, Jorgensen, R, Andersen, G.R, Beckmann, R, Penczek, P.A, Ballesta, J.P.G, Frank, J.
Deposit date:2004-01-06
Release date:2014-07-09
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (11.7 Å)
Cite:Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation.
Embo J., 23, 2004
5WLU
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BU of 5wlu by Molmil
Carbonic Anhydrase IX-mimic in complex with aryloxy-2-hydroxypropylammine sulfonamide
Descriptor: 4-{(2R)-2-hydroxy-3-[(propan-2-yl)amino]propoxy}-N-[2-(4-sulfamoylphenyl)ethyl]benzamide, Carbonic Anhydrase IX-mimic, ZINC ION
Authors:Lomelino, C.L, Andring, J.T, McKenna, R.
Deposit date:2017-07-27
Release date:2018-08-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Hybrids for multitargeted therapy Beta Adrenergic Receptor modulators CAIs
To Be Published
6OAR
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BU of 6oar by Molmil
Structure of the Kupe virus OTU bound to the C-terminal domain of sheep ISG15
Descriptor: Interferon stimulated gene 17, RNA-dependent RNA polymerase, prop-2-en-1-amine
Authors:Dzimianski, J.V, Williams, I.L, Pegan, S.D.
Deposit date:2019-03-18
Release date:2020-01-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.063 Å)
Cite:Determining the molecular drivers of species-specific interferon-stimulated gene product 15 interactions with nairovirus ovarian tumor domain proteases.
Plos One, 14, 2019
6OAT
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BU of 6oat by Molmil
Structure of the Ganjam virus OTU bound to sheep ISG15
Descriptor: Interferon stimulated gene 17, RNA-dependent RNA polymerase, prop-2-en-1-amine
Authors:Dzimianski, J.V, Williams, I.L, Pegan, S.D.
Deposit date:2019-03-18
Release date:2020-01-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Determining the molecular drivers of species-specific interferon-stimulated gene product 15 interactions with nairovirus ovarian tumor domain proteases.
Plos One, 14, 2019
2OHX
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BU of 2ohx by Molmil
REFINED CRYSTAL STRUCTURE OF LIVER ALCOHOL DEHYDROGENASE-NADH COMPLEX AT 1.8 ANGSTROMS RESOLUTION
Descriptor: ALCOHOL DEHYDROGENASE, DIMETHYL SULFOXIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Al-Karadaghi, S, Cedergren-Zeppezauer, E.S.
Deposit date:1993-08-24
Release date:1993-10-31
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Refined crystal structure of liver alcohol dehydrogenase-NADH complex at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 50, 1994
6YAL
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BU of 6yal by Molmil
Mammalian 48S late-stage initiation complex with beta-globin mRNA
Descriptor: 18S ribosomal RNA, 40S Ribosomal protein uS3, 40S Ribosomal protein uS7, ...
Authors:Bochler, A, Simonetti, A, Guca, E, Hashem, Y.
Deposit date:2020-03-12
Release date:2020-04-08
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural Insights into the Mammalian Late-Stage Initiation Complexes.
Cell Rep, 31, 2020
1Y2S
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BU of 1y2s by Molmil
Ovine Prion Protein Variant R168
Descriptor: Major prion protein
Authors:Christen, B, Lysek, D.A, Herrmann, T, Wuthrich, K.
Deposit date:2004-11-23
Release date:2004-12-28
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Prion protein NMR structures of cats, dogs, pigs, and sheep
Proc.Natl.Acad.Sci.USA, 102, 2005
6YAN
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BU of 6yan by Molmil
Mammalian 48S late-stage translation initiation complex with histone 4 mRNA
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S12, 40S ribosomal protein S21, ...
Authors:Bochler, A, Simonetti, A, Guca, E, Hashem, Y.
Deposit date:2020-03-12
Release date:2020-04-08
Last modified:2020-04-22
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:Structural Insights into the Mammalian Late-Stage Initiation Complexes.
Cell Rep, 31, 2020
7ASE
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BU of 7ase by Molmil
43S preinitiation complex from Trypanosoma cruzi with the kDDX60 helicase
Descriptor: 18S, 40S ribosomal protein S10, putative, ...
Authors:Bochler, A, Brito Querido, J, Prilepskaja, T, Soufari, H, Del Cistia, M.L, Kuhn, L, Rimoldi Ribeiro, A, Valasek, L.S, Hashem, Y.
Deposit date:2020-10-27
Release date:2021-04-14
Last modified:2021-04-21
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts.
Cell Rep, 33, 2020
4L8A
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BU of 4l8a by Molmil
Crystal structure of a GNAT superfamily acetyltransferase PA4794 in ternary complex with N-Phenylacetyl-Gly-AcLys and CoA
Descriptor: 1,2-ETHANEDIOL, COENZYME A, N-(phenylacetyl)glycyl-N~6~-acetyl-L-lysine, ...
Authors:Majorek, K.A, Chruszcz, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
Deposit date:2013-06-16
Release date:2013-07-10
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa.
J.Biol.Chem., 288, 2013

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數據於2024-09-11公開中

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