PDB: 72308 resultsInfo pagesStatus searchChemie searchBIRD

---

8WT8	Cryo-EM structure of the IS621 recombinase in complex with bridge RNA, donor DNA, and target DNA in the post-strand exchange state (Holliday junction intermediate) Descriptor: IS621 transposase, MAGNESIUM ION, bridge RNA, ... Authors: Hiraizumi, M, Yamashita, K, Nishimasu, H. Deposit date: 2023-10-18 Release date: 2024-06-26 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural mechanism of bridge RNA-guided recombination Nature, 630, 2024
8WT9	Cryo-EM structure of the IS621 recombinase in complex with bridge RNA, donor DNA, and target DNA in the post-strand exchange state (Holliday junction resolution) Descriptor: IS621 transposase, MAGNESIUM ION, bridge RNA, ... Authors: Hiraizumi, M, Yamashita, K, Nishimasu, H. Deposit date: 2023-10-18 Release date: 2024-06-26 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Structural mechanism of bridge RNA-guided recombination Nature, 630, 2024
5HN0	Dengue serotype 3 RNA-dependent RNA polymerase bound to compound 4 Descriptor: (6-hydroxybiphenyl-3-yl)acetic acid, RNA-directed RNA polymerase NS5, ZINC ION Authors: Noble, C.G. Deposit date: 2016-01-17 Release date: 2016-03-30 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design. J.Med.Chem., 59, 2016
6CO2	Structure of an engineered protein (NUDT16TI) in complex with 53BP1 Tudor domains Descriptor: NUDT16-Tudor-interacting (NUDT16TI), TP53-binding protein 1 Authors: Botuyan, M.V, Thompson, J.R, Cui, G, Mer, G. Deposit date: 2018-03-10 Release date: 2018-06-06 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.49 Å) Cite: Mechanism of 53BP1 activity regulation by RNA-binding TIRR and a designer protein. Nat. Struct. Mol. Biol., 25, 2018
1GTC	HUMAN IMMUNODEFICIENCY VIRUS-1 OKAZAKI FRAGMENT, DNA-RNA CHIMERA, NMR, 11 STRUCTURES Descriptor: DNA (5'-D(*GP*CP*AP*GP*TP*GP*GP*C)-3'), DNA/RNA (5'-R(*GP*CP*CP*A)-D(P*CP*TP*GP*C)-3') Authors: Fedoroff, O.Y, Salazar, M, Reid, B.R. Deposit date: 1996-06-13 Release date: 1996-12-23 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structural variation among retroviral primer-DNA junctions: solution structure of the HIV-1 (-)-strand Okazaki fragment r(gcca)d(CTGC).d(GCAGTGGC). Biochemistry, 35, 1996
3P26	Crystal structure of S. cerevisiae Hbs1 protein (apo-form), a translational GTPase involved in RNA quality control pathways and interacting with Dom34/Pelota Descriptor: Elongation factor 1 alpha-like protein Authors: van den Elzen, A, Henri, J, Lazar, N, Gas, M.E, Durand, D, Lacroute, F, Nicaise, M, van Tilbeurgh, H, Sraphin, B, Graille, M, Paris-Sud Yeast Structural Genomics (YSG) Deposit date: 2010-10-01 Release date: 2010-11-17 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Dissection of Dom34-Hbs1 reveals independent functions in two RNA quality control pathways. Nat.Struct.Mol.Biol., 17, 2010
7F8B	Crystal structure of rRNA methyltransferase Erm38 in complex with SAM Descriptor: Erm(38), S-ADENOSYLMETHIONINE, SUCCINIC ACID Authors: Goh, B.C, Lescar, J. Deposit date: 2021-07-01 Release date: 2022-01-12 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.248 Å) Cite: Crystal structure and functional analysis of mycobacterial erythromycin resistance methyltransferase Erm38 reveals its RNA-binding site. J.Biol.Chem., 298, 2022
7F8A	Crystal structure of rRNA methyltransferase Erm38 Descriptor: Erm(38) Authors: Goh, B.C, Lescar, J. Deposit date: 2021-07-01 Release date: 2022-01-12 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure and functional analysis of mycobacterial erythromycin resistance methyltransferase Erm38 reveals its RNA-binding site. J.Biol.Chem., 298, 2022
7F8C	Crystal structure of rRNA methyltransferase Erm38 in complex with sinefungin Descriptor: Erm(38), SINEFUNGIN, SUCCINIC ACID Authors: Goh, B.C, Lescar, J. Deposit date: 2021-07-01 Release date: 2022-01-12 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.248 Å) Cite: Crystal structure and functional analysis of mycobacterial erythromycin resistance methyltransferase Erm38 reveals its RNA-binding site. J.Biol.Chem., 298, 2022
1FYP	EUKARYOTIC DECODING REGION A-SITE RNA-PAROMOMYCIN COMPLEX Descriptor: FRAGMENT OF 18S RIBOSOMAL RNA, PAROMOMYCIN Authors: Lynch, S.R, Puglisi, J.D. Deposit date: 2000-10-02 Release date: 2001-03-14 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structural origins of aminoglycoside specificity for prokaryotic ribosomes. J.Mol.Biol., 306, 2001
3P27	Crystal structure of S. cerevisiae Hbs1 protein (GDP-bound form), a translational GTPase involved in RNA quality control pathways and interacting with Dom34/Pelota Descriptor: Elongation factor 1 alpha-like protein, GUANOSINE-5'-DIPHOSPHATE Authors: van den Elzen, A, Henri, J, Lazar, N, Gas, M.E, Durand, D, Lacroute, F, Nicaise, M, van Tilbeurgh, H, Sraphin, B, Graille, M, Paris-Sud Yeast Structural Genomics (YSG) Deposit date: 2010-10-01 Release date: 2010-11-17 Last modified: 2012-03-14 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Dissection of Dom34-Hbs1 reveals independent functions in two RNA quality control pathways. Nat.Struct.Mol.Biol., 17, 2010
2F8K	Sequence specific recognition of RNA hairpins by the SAM domain of Vts1 Descriptor: 5'-R(*UP*AP*AP*UP*CP*UP*UP*UP*GP*AP*CP*AP*GP*AP*UP*U)-3', Protein VTS1 Authors: Aviv, T, Lin, Z, Ben-Ari, G, Smibert, C.A, Sicheri, F. Deposit date: 2005-12-02 Release date: 2006-01-24 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2 Å) Cite: Sequence-specific recognition of RNA hairpins by the SAM domain of Vts1p. Nat.Struct.Mol.Biol., 13, 2006
7OX8	Target-bound SpCas9 complex with TRAC full RNA guide Descriptor: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, POTASSIUM ION, ... Authors: Donohoue, P, Pacesa, M, Lau, E, Vidal, B, Irby, M.J, Nyer, D.B, Rotstein, T, Banh, L, Toh, M.T, Gibson, J, Kohrs, B, Baek, K, Owen, A.L.G, Slorach, E.M, van Overbeek, M, Fuller, C.K, May, A.P, Jinek, M, Cameron, P. Deposit date: 2021-06-22 Release date: 2021-09-15 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Conformational control of Cas9 by CRISPR hybrid RNA-DNA guides mitigates off-target activity in T cells. Mol.Cell, 81, 2021
5KX9	Selective Small Molecule Inhibition of the FMN Riboswitch Descriptor: (6P)-2-{(3S)-1-[(2-methoxypyrimidin-5-yl)methyl]piperidin-3-yl}-6-(thiophen-2-yl)pyrimidin-4-ol, FMN Riboswitch, MAGNESIUM ION, ... Authors: Fischmann, T.O. Deposit date: 2016-07-20 Release date: 2016-08-24 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Atomic resolution mechanistic studies of ribocil: A highly selective unnatural ligand mimic of the E. coli FMN riboswitch. Rna Biol., 13, 2016
8TJX	Tetrahymena Ribozyme cryo-EM scaffold Descriptor: MAGNESIUM ION, RNA (440-MER) Authors: Langeberg, C.J, Kieft, J.S. Deposit date: 2023-07-24 Release date: 2023-11-01 Last modified: 2023-11-22 Method: ELECTRON MICROSCOPY (2.44 Å) Cite: A generalizable scaffold-based approach for structure determination of RNAs by cryo-EM. Nucleic Acids Res., 51, 2023
5ZTB	Structure of Sulfurtransferase Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, IRON/SULFUR CLUSTER, ... Authors: Tanaka, Y, Chen, M, Narai, S, Yao, M. Deposit date: 2018-05-02 Release date: 2019-06-12 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: The [4Fe-4S] cluster of sulfurtransferase TtuA desulfurizes TtuB during tRNA modification in Thermus thermophilus. Commun Biol, 3, 2020
8H27	Crystal structure of MnmM from S. aureus complexed with SAM (2.04 A) Descriptor: 16S rRNA (Cytosine(1402)-N(4))-methyltransferase, S-ADENOSYLMETHIONINE Authors: Kim, J, Cho, G, Lee, J. Deposit date: 2022-10-05 Release date: 2023-01-25 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.04 Å) Cite: Identification of a novel 5-aminomethyl-2-thiouridine methyltransferase in tRNA modification. Nucleic Acids Res., 51, 2023
7OCZ	Crystal Structure of the PID-3 RRM domain Descriptor: CHLORIDE ION, Protein pid-3 Authors: Basquin, J, Ketting, R.F, Falk, S. Deposit date: 2021-04-28 Release date: 2021-08-25 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.82 Å) Cite: Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans . Genes Dev., 35, 2021
1OKA	RNA/DNA CHIMERA, NMR Descriptor: RNA/DNA CHIMERA (R(CCCA)D(AATGA)(DOT)D(TCATTTGGG)) Authors: Salazar, M, Fedoroff, O.Y, Reid, B.R. Deposit date: 1996-04-19 Release date: 1996-11-08 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Structure of chimeric duplex junctions: solution conformation of the retroviral Okazaki-like fragment r(ccca)d(AATGA).d(TCATTTGGG) from Moloney murine leukemia virus. Biochemistry, 35, 1996
6C05	Mycobacterium tuberculosis RNAP Holo/RbpA in relaxed state Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M. Deposit date: 2017-12-27 Release date: 2018-03-28 Last modified: 2019-12-18 Method: ELECTRON MICROSCOPY (5.15 Å) Cite: Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts. Elife, 7, 2018
5JAJ	Structure of chicken LGP2 witha 5'p 10-mer dsRNA and ADP-AlF4-Mg. Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, LGP2, ... Authors: Cusack, S, Uchikawa, E. Deposit date: 2016-04-12 Release date: 2016-06-01 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5. Mol.Cell, 62, 2016
1Q63	CRYSTAL STRUCTURE OF TGT IN COMPLEX WITH 2,6-Diamino-8-(1H-imidazol-2-ylsulfanylmethyl)-3H-quinazoline-4-one crystallized at pH 5.5 Descriptor: 2,6-DIAMINO-8-(1H-IMIDAZOL-2-YLSULFANYLMETHYL)-3H-QUINAZOLINE-4-ONE, Queuine tRNA-ribosyltransferase, ZINC ION Authors: Brenk, R, Meyer, E, Reuter, K, Stubbs, M.T, Garcia, G.A, Klebe, G. Deposit date: 2003-08-12 Release date: 2004-04-13 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crystallographic Study of Inhibitors of tRNA-guanine Transglycosylase Suggests a New Structure-based Pharmacophore for Virtual Screening. J.Mol.Biol., 338, 2004
5ML7	CRYSTAL STRUCTURE OF L1-STALK FRAGMENT OF 23S rRNA FROM HALOARCULA MARISMORTUI Descriptor: 23S ribosomal RNA, CALCIUM ION, MAGNESIUM ION Authors: Gabdulkhakov, A.G, Tishchenko, T.V, Nevskaya, N.A, Nikonov, S.V. Deposit date: 2016-12-06 Release date: 2017-12-20 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Crystal Structure of the 23S rRNA Fragment Specific to r-Protein L1 and Designed Model of the Ribosomal L1 Stalk from Haloarcula marismortui Crystals, 2017
2A8Q	2.6 Angstrom Crystal Structure of the Complex Between the Nuclear SnoRNA Decapping Nudix Hydrolase X29 and Manganese in the Presence of 7-methyl-GDP Descriptor: MANGANESE (II) ION, PYROPHOSPHATE 2-, U8 snoRNA-binding protein X29 Authors: Scarsdale, J.N, Peculis, B.A, Wright, H.T. Deposit date: 2005-07-08 Release date: 2006-03-28 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal structures of U8 snoRNA decapping nudix hydrolase, X29, and its metal and cap complexes Structure, 14, 2006
2A8S	2.45 Angstrom Crystal Structure of the Complex Between the Nuclear SnoRNA Decapping Nudix Hydrolase X29, Manganese and GTP Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, U8 snoRNA-binding protein X29 Authors: Scarsdale, J.N, Peculis, B.A, Wright, H.T. Deposit date: 2005-07-08 Release date: 2006-03-28 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Crystal structures of U8 snoRNA decapping nudix hydrolase, X29, and its metal and cap complexes Structure, 14, 2006

<279280281282283284285286287288289290291292293294>