5AQJ
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![BU of 5aqj by Molmil](/molmil-images/mine/5aqj) | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 9H-purine-6,8-diamine, BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1, ... | Authors: | Jones, A.M, Westwood, I.M, Osborne, J.D, Matthews, T.P, Cheeseman, M.D, Rowlands, M.G, Jeganathan, F, Burke, R, Lee, D, Kadi, N, Liu, M, Richards, M, McAndrew, C, Yahya, N, Dobson, S.E, Jones, K, Workman, P, Collins, I, van Montfort, R.L.M. | Deposit date: | 2015-09-22 | Release date: | 2016-10-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms. Sci Rep, 6, 2016
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5AQF
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![BU of 5aqf by Molmil](/molmil-images/mine/5aqf) | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE, BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1, ... | Authors: | Jones, A.M, Westwood, I.M, Osborne, J.D, Matthews, T.P, Cheeseman, M.D, Rowlands, M.G, Jeganathan, F, Burke, R, Lee, D, Kadi, N, Liu, M, Richards, M, McAndrew, C, Yahya, N, Dobson, S.E, Jones, K, Workman, P, Collins, I, van Montfort, R.L.M. | Deposit date: | 2015-09-22 | Release date: | 2016-10-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms. Sci Rep, 6, 2016
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4LFM
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![BU of 4lfm by Molmil](/molmil-images/mine/4lfm) | |
5AQK
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![BU of 5aqk by Molmil](/molmil-images/mine/5aqk) | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1, DIMETHYL SULFOXIDE, ... | Authors: | Jones, A.M, Westwood, I.M, Osborne, J.D, Matthews, T.P, Cheeseman, M.D, Rowlands, M.G, Jeganathan, F, Burke, R, Lee, D, Kadi, N, Liu, M, Richards, M, McAndrew, C, Yahya, N, Dobson, S.E, Jones, K, Workman, P, Collins, I, van Montfort, R.L.M. | Deposit date: | 2015-09-22 | Release date: | 2016-10-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms. Sci Rep, 6, 2016
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5AQQ
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![BU of 5aqq by Molmil](/molmil-images/mine/5aqq) | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 7-methylquinazolin-4-amine, BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1, ... | Authors: | Jones, A.M, Westwood, I.M, Osborne, J.D, Matthews, T.P, Cheeseman, M.D, Rowlands, M.G, Jeganathan, F, Burke, R, Lee, D, Kadi, N, Liu, M, Richards, M, McAndrew, C, Yahya, N, Dobson, S.E, Jones, K, Workman, P, Collins, I, van Montfort, R.L.M. | Deposit date: | 2015-09-22 | Release date: | 2016-10-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms. Sci Rep, 6, 2016
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5AQR
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![BU of 5aqr by Molmil](/molmil-images/mine/5aqr) | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-methoxyquinazolin-4-amine, BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1, ... | Authors: | Jones, A.M, Westwood, I.M, Osborne, J.D, Matthews, T.P, Cheeseman, M.D, Rowlands, M.G, Jeganathan, F, Burke, R, Lee, D, Kadi, N, Liu, M, Richards, M, McAndrew, C, Yahya, N, Dobson, S.E, Jones, K, Workman, P, Collins, I, van Montfort, R.L.M. | Deposit date: | 2015-09-22 | Release date: | 2016-10-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms. Sci Rep, 6, 2016
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4LFK
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![BU of 4lfk by Molmil](/molmil-images/mine/4lfk) | |
4LFL
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![BU of 4lfl by Molmil](/molmil-images/mine/4lfl) | |
4LN5
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![BU of 4ln5 by Molmil](/molmil-images/mine/4ln5) | Crystal structure of a trap periplasmic solute binding protein from burkholderia ambifaria (Bamb_6123), TARGET EFI-510059, with bound glycerol and chloride ion | Descriptor: | CHLORIDE ION, GLYCEROL, TRAP dicarboxylate transporter, ... | Authors: | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2013-07-11 | Release date: | 2013-08-14 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes. Biochemistry, 54, 2015
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4LFN
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![BU of 4lfn by Molmil](/molmil-images/mine/4lfn) | |
3RSV
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![BU of 3rsv by Molmil](/molmil-images/mine/3rsv) | |
4OST
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![BU of 4ost by Molmil](/molmil-images/mine/4ost) | Crystal structure of the S505C mutant of TAL effector dHax3 | Descriptor: | DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*AP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3 | Authors: | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | Deposit date: | 2014-02-13 | Release date: | 2014-05-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.996 Å) | Cite: | Revisiting the TALE repeat Protein Cell, 5, 2014
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3RTM
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![BU of 3rtm by Molmil](/molmil-images/mine/3rtm) | |
4OSK
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![BU of 4osk by Molmil](/molmil-images/mine/4osk) | Crystal structure of TAL effector reveals the recognition between asparagine and guanine | Descriptor: | DNA (5'-D(*AP*GP*TP*CP*TP*AP*GP*TP*AP*GP*TP*TP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*AP*AP*CP*TP*AP*CP*TP*AP*GP*AP*CP*T)-3'), Hax3 | Authors: | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | Deposit date: | 2014-02-13 | Release date: | 2014-05-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.398 Å) | Cite: | Revisiting the TALE repeat Protein Cell, 5, 2014
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4OT0
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![BU of 4ot0 by Molmil](/molmil-images/mine/4ot0) | Crystal structure of the S505T mutant of TAL effector dHax3 | Descriptor: | DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*AP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3 | Authors: | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | Deposit date: | 2014-02-13 | Release date: | 2014-05-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.491 Å) | Cite: | Revisiting the TALE repeat Protein Cell, 5, 2014
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3QKQ
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![BU of 3qkq by Molmil](/molmil-images/mine/3qkq) | Protein Tyrosine Phosphatase 1B - W179F mutant bound with vanadate | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Tyrosine-protein phosphatase non-receptor type 1, ... | Authors: | Brandao, T.A.S, Johnson, S.J, Hengge, A.C. | Deposit date: | 2011-02-01 | Release date: | 2012-08-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The molecular details of WPD-loop movement differ in the protein-tyrosine phosphatases YopH and PTP1B. Arch.Biochem.Biophys., 525, 2012
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3RTN
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![BU of 3rtn by Molmil](/molmil-images/mine/3rtn) | |
3R8X
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![BU of 3r8x by Molmil](/molmil-images/mine/3r8x) | Crystal Structure of Methionyl-tRNA Formyltransferase from Yersinia pestis complexed with L-methionine | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, METHIONINE, ... | Authors: | Maltseva, N, Kim, Y, Hasseman, J, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2011-03-24 | Release date: | 2011-04-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.256 Å) | Cite: | Crystal Structure of Methionyl-tRNA Formyltransferase
from Yersinia pestis complexed with L-methionine To be Published
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4OSL
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![BU of 4osl by Molmil](/molmil-images/mine/4osl) | Crystal structure of TAL effector reveals the recognition between histidine and guanine | Descriptor: | DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*CP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*GP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3, ... | Authors: | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | Deposit date: | 2014-02-13 | Release date: | 2014-05-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.447 Å) | Cite: | Revisiting the TALE repeat Protein Cell, 5, 2014
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4OT3
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![BU of 4ot3 by Molmil](/molmil-images/mine/4ot3) | Crystal structure of the S505L mutant of TAL effector dHax3 | Descriptor: | DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*AP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3 | Authors: | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | Deposit date: | 2014-02-13 | Release date: | 2014-05-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.944 Å) | Cite: | Revisiting the TALE repeat Protein Cell, 5, 2014
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4OSV
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![BU of 4osv by Molmil](/molmil-images/mine/4osv) | Crystal structure of the S505M mutant of TAL effector dHax3 | Descriptor: | DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*AP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3 | Authors: | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | Deposit date: | 2014-02-13 | Release date: | 2014-05-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.996 Å) | Cite: | Revisiting the TALE repeat Protein Cell, 5, 2014
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4OSM
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![BU of 4osm by Molmil](/molmil-images/mine/4osm) | Crystal structure of the S505H mutant of TAL effector dHax3 | Descriptor: | DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*AP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3 | Authors: | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | Deposit date: | 2014-02-13 | Release date: | 2014-05-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.454 Å) | Cite: | Revisiting the TALE repeat Protein Cell, 5, 2014
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3U41
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![BU of 3u41 by Molmil](/molmil-images/mine/3u41) | |
4OSI
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![BU of 4osi by Molmil](/molmil-images/mine/4osi) | Crystal structure of the TAL effector dHax3 with NI RVD at 2.8 angstrom resolution | Descriptor: | DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*AP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3 | Authors: | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | Deposit date: | 2014-02-13 | Release date: | 2014-05-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.849 Å) | Cite: | Revisiting the TALE repeat Protein Cell, 5, 2014
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4OSZ
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![BU of 4osz by Molmil](/molmil-images/mine/4osz) | Crystal structure of the S505P mutant of TAL effector dHax3 | Descriptor: | DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*AP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3 | Authors: | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | Deposit date: | 2014-02-13 | Release date: | 2014-05-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.614 Å) | Cite: | Revisiting the TALE repeat Protein Cell, 5, 2014
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