PDB: 618 resultsInfo pagesStatus searchChemie searchBIRD

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8VXC	Structure of HamB-DNA complex, conformation 2, from the Escherichia coli Hachiman defense system Descriptor: DNA (40-MER), HamB Authors: Tuck, O.T, Doudna, J.A. Deposit date: 2024-02-04 Release date: 2024-03-13 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (2.93 Å) Cite: Hachiman is a genome integrity sensor. Biorxiv, 2024
8VXY	Structure of HamA(E138A,K140A)B-plasmid DNA complex from the Escherichia coli Hachiman defense system Descriptor: ADENOSINE-5'-TRIPHOSPHATE, HamA, HamB, ... Authors: Tuck, O.T, Hu, J.J, Doudna, J.A. Deposit date: 2024-02-06 Release date: 2024-03-13 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.19 Å) Cite: Hachiman is a genome integrity sensor. Biorxiv, 2024
8W0A	Human DNA polymerase theta helicase domain in complex with ssDNA, dimer form Descriptor: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*T)-3'), DNA polymerase theta Authors: Ito, F, Li, Z, Chen, X.S. Deposit date: 2024-02-13 Release date: 2024-06-26 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining. Biorxiv, 2024
9ASJ	Human DNA polymerase theta helicase domain in complex with AMP-PNP, dimer form Descriptor: DNA polymerase theta, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER Authors: Ito, F, Li, Z, Chen, X.S. Deposit date: 2024-02-26 Release date: 2024-06-26 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining. Biorxiv, 2024
9ASL	Human DNA polymerase theta helicase domain tetramer, apo-form Descriptor: DNA polymerase theta Authors: Ito, F, Li, Z, Chen, X.S. Deposit date: 2024-02-26 Release date: 2024-06-26 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining. Biorxiv, 2024
9ASK	Human DNA polymerase theta helicase domain dimer, apo-form Descriptor: DNA polymerase theta Authors: Ito, F, Li, Z, Chen, X.S. Deposit date: 2024-02-26 Release date: 2024-06-26 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining. Biorxiv, 2024
8YLE	Crystal structure of Werner syndrome helicase complexed with AMP-PCP Descriptor: 1,2-ETHANEDIOL, Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... Authors: Yang, Y, Fu, L, Sun, X, Cheng, H, Chen, R. Deposit date: 2024-03-06 Release date: 2024-04-10 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Structure of werner syndrome helicase complexed with AMP-PCP at 1.86 Angstroms resolution. To Be Published
8YRS	Crystal structure of human RECQ1 helicase containing a flexible linker in complex with tailed duplex DNA Descriptor: ATP-dependent DNA helicase Q1, DNA (27-MER), DNA (5'-D(*AP*GP*CP*GP*TP*CP*GP*AP*GP*AP*TP*CP*C)-3'), ... Authors: Das, T, Das, A.K, Ganguly, A. Deposit date: 2024-03-21 Release date: 2024-09-04 Method: X-RAY DIFFRACTION (2.43 Å) Cite: Crystal structure of human RECQ1 helicase containing a flexible linker in complex with tailed duplex DNA To Be Published
9BH7	Human DNA polymerase theta helicase domain dimer in the apo form Descriptor: DNA polymerase theta Authors: Zerio, C.J, Lander, G.C. Deposit date: 2024-04-19 Release date: 2024-05-01 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Human polymerase theta helicase positions DNA microhomologies for double-strand break repair To Be Published
9BH6	Human DNA polymerase theta helicase domain tetramer in the apo form Descriptor: DNA polymerase theta Authors: Zerio, C.J, Lander, G.C. Deposit date: 2024-04-19 Release date: 2024-05-01 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Human polymerase theta helicase positions DNA microhomologies for double-strand break repair To Be Published
9BH8	Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology searching conformation Descriptor: DNA polymerase theta, Stem-loop DNA with microhomology in the 3' overhang Authors: Zerio, C.J, Lander, G.C. Deposit date: 2024-04-19 Release date: 2024-05-01 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Human polymerase theta helicase positions DNA microhomologies for double-strand break repair To Be Published
9BHA	Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology annealed conformation Descriptor: DNA polymerase theta, Stem-loop DNA with microhomology in the 3' overhang Authors: Zerio, C.J, Lander, G.C. Deposit date: 2024-04-19 Release date: 2024-05-01 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Human polymerase theta helicase positions DNA microhomologies for double-strand break repair To Be Published
9BH9	Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology aligning conformation Descriptor: DNA polymerase theta, Stem-loop DNA with microhomology in the 3' overhang Authors: Zerio, C.J, Lander, G.C. Deposit date: 2024-04-19 Release date: 2024-05-01 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Human polymerase theta helicase positions DNA microhomologies for double-strand break repair To Be Published
9BLN	The structure of human Pdcd4 bound to the 40S-eIF4A-eIF3-eIF1 complex Descriptor: 40S ribosomal protein S14, ACETIC ACID, Eukaryotic initiation factor 4A-I, ... Authors: Brito Querido, J, Sokabe, M, Diaz-Lopez, I, Gordiyenko, Y, Zuber, P, Yifei, D, Albacete-Albacete, L, Ramakrishnan, V, S Fraser, C. Deposit date: 2024-04-30 Release date: 2024-09-04 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in the 40S small ribosomal subunit. Nat Commun, 15, 2024
9BP9	Human DNA polymerase theta helicase domain in complex with inhibitor AB25583, dimer form Descriptor: (4P)-N-{5-[(4-chlorophenyl)methoxy]-1,3,4-thiadiazol-2-yl}-4-(2-methoxyphenyl)pyridine-3-carboxamide, DNA polymerase theta Authors: Ito, F, Li, Z, Chen, X.S. Deposit date: 2024-05-07 Release date: 2024-08-28 Method: ELECTRON MICROSCOPY (3.21 Å) Cite: Structural basis for a Pol theta helicase small-molecule inhibitor revealed by cryo-EM. Nat Commun, 15, 2024
9BPA	Human DNA polymerase theta helicase domain in complex with inhibitor AB25583, tetramer form Descriptor: (4P)-N-{5-[(4-chlorophenyl)methoxy]-1,3,4-thiadiazol-2-yl}-4-(2-methoxyphenyl)pyridine-3-carboxamide, DNA polymerase theta Authors: Ito, F, Li, Z, Chen, X.S. Deposit date: 2024-05-07 Release date: 2024-08-28 Method: ELECTRON MICROSCOPY (3.21 Å) Cite: Structural basis for a Pol theta helicase small-molecule inhibitor revealed by cryo-EM. Nat Commun, 15, 2024
9FMD	Integrative model of the human post-catalytic spliceosome (P-complex) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... Authors: Rothe, P, Plaschka, C, Vorlaender, M.K. Deposit date: 2024-06-05 Release date: 2024-07-10 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Mechanism for the initiation of spliceosome disassembly. Nature, 2024
9C5Q	Human DNA polymerase theta helicase domain in microhomology annealed state 2, dimer form Descriptor: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*CP*CP*CP*GP*GP*G)-3'), DNA polymerase theta Authors: Ito, F, Li, Z, Chen, X.S. Deposit date: 2024-06-06 Release date: 2024-06-26 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural Basis for Pol theta-Helicase DNA Binding and Microhomology-Mediated End-Joining. Biorxiv, 2024

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