9CU9
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![BU of 9cu9 by Molmil](/molmil-images/mine/9cu9) | Crystal structure of Staphylococcal nuclease variant Delta+PHS V23D/L36K at cryogenic temperature | Descriptor: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | Authors: | Zhang, Y, Schlessman, J.L, Robinson, A.C, Garcia-Moreno E, B. | Deposit date: | 2024-07-26 | Release date: | 2024-08-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of Staphylococcal nuclease variant Delta+PHS V23D/L36K at cryogenic temperature To Be Published
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9CTX
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![BU of 9ctx by Molmil](/molmil-images/mine/9ctx) | X-ray crystal structure of multi-drug resistant HIV-1 protease (P51) in complex with Darunavir | Descriptor: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, GLYCEROL, Protease | Authors: | Hayashi, H, Yedidi, R, Bulut, H, Das, D, Mitsuya, H. | Deposit date: | 2024-07-25 | Release date: | 2024-08-07 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Secondary amino-acid substitutions contribute to the emergence of HIV protease inhibitor resistance as directly as primary amino-acid substitutions. To Be Published
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9CTH
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![BU of 9cth by Molmil](/molmil-images/mine/9cth) | Preliminary map of the Prothrombin-prothrombinase complex on nano discs | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Activated Factor V (FVa) heavy chain, Activated Factor V (FVa) light chain, ... | Authors: | Stojanovski, B.M, Mohammed, B.M, Di Cera, E. | Deposit date: | 2024-07-25 | Release date: | 2024-08-07 | Last modified: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (6.47 Å) | Cite: | The Prothrombin-Prothrombinase Interaction. Subcell Biochem, 104, 2024
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9CSI
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![BU of 9csi by Molmil](/molmil-images/mine/9csi) | A. baumannii MsbA Bound to Cerastecin Compound 5 | Descriptor: | 3,3'-[(1,4-dioxobutane-1,4-diyl)bis(azanediyl)]bis[(4-butylbenzene-1-sulfonamido)benzoic acid], Lipid A export ATP-binding/permease protein MsbA, MAGNESIUM ION, ... | Authors: | Klein, D.J, Ishchenko, A, Soisson, S, Cheng, R, Hennig, M. | Deposit date: | 2024-07-23 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Cerastecin Inhibition of the Lipooligosaccharide Transporter MsbA to Combat Acinetobacter baumannii : From Screening Impurity to In Vivo Efficacy. J.Med.Chem., 2024
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9CSG
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![BU of 9csg by Molmil](/molmil-images/mine/9csg) | Human Serum Albumin Bound to Cerastecin Compound 5e | Descriptor: | 2-(4-butylbenzene-1-sulfonamido)-5-(4-{3-carboxy-4-[4-(2-methoxyethyl)benzene-1-sulfonamido]anilino}-4-oxobutanamido)benzoic acid, Albumin, MYRISTIC ACID | Authors: | Hruza, A, Klein, D.J, Ishchenko, A. | Deposit date: | 2024-07-23 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.914 Å) | Cite: | Cerastecin Inhibition of the Lipooligosaccharide Transporter MsbA to Combat Acinetobacter baumannii : From Screening Impurity to In Vivo Efficacy. J.Med.Chem., 2024
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9CRW
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![BU of 9crw by Molmil](/molmil-images/mine/9crw) | Crystal structure of the Candida albicans kinesin-8 proximal tail domain | Descriptor: | Kinesin-like protein | Authors: | Trofimova, D, Doubleday, C, Hunter, B, Serrano Arevalo, J, Davison, E, Wen, E, Munro, K, Allingham, J.S. | Deposit date: | 2024-07-22 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Crystal structure of the Candida albicans kinesin-8 proximal tail domain To Be Published
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9CRN
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9CPO
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![BU of 9cpo by Molmil](/molmil-images/mine/9cpo) | |
9CPL
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9CPJ
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![BU of 9cpj by Molmil](/molmil-images/mine/9cpj) | Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1 | Descriptor: | RNA (5'-R(*GP*AP*CP*AP*GP*CP*UP*GP*CP*UP*GP*UP*C)-3') | Authors: | Chen, J.L, Taghavi, A, Disney, M.D, Fountain, M.A, Childs-Disney, J.L. | Deposit date: | 2024-07-18 | Release date: | 2024-08-07 | Method: | SOLUTION NMR | Cite: | Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1. Bioorg.Med.Chem.Lett., 2024
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9CPI
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![BU of 9cpi by Molmil](/molmil-images/mine/9cpi) | Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1 | Descriptor: | 4-[1-(2-aminoethyl)-4,5-dihydro-1H-imidazol-2-yl]-N-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]benzamide, RNA (5'-R(*GP*AP*CP*AP*GP*CP*UP*GP*CP*UP*GP*UP*C)-3') | Authors: | Chen, J.L, Taghavi, A, Disney, M.D, Fountain, M.A, Childs-Disney, J.L. | Deposit date: | 2024-07-18 | Release date: | 2024-08-07 | Last modified: | 2024-08-14 | Method: | SOLUTION NMR | Cite: | NMR structures of small molecules bound to a model of a CUG RNA repeat expansion. Bioorg.Med.Chem.Lett., 111, 2024
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9CPG
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![BU of 9cpg by Molmil](/molmil-images/mine/9cpg) | Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1 | Descriptor: | 4-carbamimidamidophenyl 4-carbamimidamidobenzoate, RNA (5'-R(*GP*AP*CP*AP*GP*CP*UP*GP*CP*UP*GP*UP*C)-3') | Authors: | Chen, J.L, Taghavi, A, Disney, M.D, Fountain, M.A, Childs-Disney, J.L. | Deposit date: | 2024-07-18 | Release date: | 2024-08-07 | Method: | SOLUTION NMR | Cite: | Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1. Bioorg.Med.Chem.Lett., 2024
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9CPD
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![BU of 9cpd by Molmil](/molmil-images/mine/9cpd) | Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1 | Descriptor: | 4-[(3-methoxyphenyl)amino]-2-methylquinoline-6-carboximidamide, RNA (5'-R(*GP*AP*CP*AP*GP*CP*UP*GP*CP*UP*GP*UP*C)-3') | Authors: | Chen, J.L, Taghavi, A, Disney, M.D, Fountain, M.A, Childs-Disney, J.L. | Deposit date: | 2024-07-18 | Release date: | 2024-08-07 | Last modified: | 2024-08-14 | Method: | SOLUTION NMR | Cite: | NMR structures of small molecules bound to a model of a CUG RNA repeat expansion. Bioorg.Med.Chem.Lett., 111, 2024
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9COZ
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9COJ
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![BU of 9coj by Molmil](/molmil-images/mine/9coj) | SH3-like tandem domain of human KIN protein | Descriptor: | DNA/RNA-binding protein KIN17 | Authors: | de Lourenco, I.O, Fossey, M.A, Souza, F.P, Seixas, F.A.V, Fernandez, M.A, Almeida, F.C.L, Caruso, I.P. | Deposit date: | 2024-07-16 | Release date: | 2024-07-31 | Method: | SOLUTION NMR | Cite: | Solution structure of SH3-like tandem domain of human KIN protein and its interaction with RNA homo-oligonucleotides To Be Published
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9CMZ
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9CMI
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9CMH
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9CLY
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![BU of 9cly by Molmil](/molmil-images/mine/9cly) | Crystal structure of the 3-ketoacyl-(acyl-carrier-protein) reductase, CylG, from Streptococcus agalactiae 2603V/R | Descriptor: | CylG protein, IMIDAZOLE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Maltseva, N, Kim, Y, Endres, M, Joachimiak, A, Center for Structural Biology of Infectious Diseases (CSBID) | Deposit date: | 2024-07-12 | Release date: | 2024-07-24 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Crystal structure of the 3-ketoacyl-(acyl-carrier-protein) reductase, CylG, from Streptococcus agalactiae 2603V/R To be published
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9CLP
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9CL9
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![BU of 9cl9 by Molmil](/molmil-images/mine/9cl9) | WT 12C IM fraction, B-b3 with RluB bound | Descriptor: | 23S rRNA, Large ribosomal subunit protein bL20, Large ribosomal subunit protein bL21, ... | Authors: | Lee, J, Sheng, K, Williamson, J.R. | Deposit date: | 2024-07-10 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (5.04 Å) | Cite: | 50S ribosome assembly intermediates at low temperature reveal bound RluB To Be Published
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9CKV
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![BU of 9ckv by Molmil](/molmil-images/mine/9ckv) | Cryo-EM structure of alpha5beta1 integrin in complex with NeoNectin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Werther, R, Nguyen, A, Estrada Alamo, K.A, Wang, X, Campbell, M.G. | Deposit date: | 2024-07-09 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.19 Å) | Cite: | De Novo Design of Integrin alpha5beta1 Modulating Proteins for Regenerative Medicine To Be Published
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9CK3
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![BU of 9ck3 by Molmil](/molmil-images/mine/9ck3) | Cryo-EM structure of in-vitro alpha-synuclein fibril | Descriptor: | Alpha-synuclein | Authors: | Sanchez, J.C, Borcik, C.G, Tonelli, M, Sibert, B, Rienstra, C.M, Wright, E.R. | Deposit date: | 2024-07-08 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (2.04 Å) | Cite: | Multimodal High-Resolution Structure Determination Of Alpha-Synuclein Fibrils To Be Published
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9CK0
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9CJA
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![BU of 9cja by Molmil](/molmil-images/mine/9cja) | |