2F5O
| MutM crosslinked to undamaged DNA sampling G:C base pair IC3 | Descriptor: | 5'-D(*AP*GP*GP*TP*AP*GP*AP*TP*CP*CP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*C*GP*TP*CP*CP*GP*GP*AP*TP*CP*TP*AP*CP*C)-3', GLYCEROL, ... | Authors: | Banerjee, A, Santos, W.L, Verdine, G.L. | Deposit date: | 2005-11-26 | Release date: | 2006-03-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure of a DNA glycosylase searching for lesions. Science, 311, 2006
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2F5P
| MutM crosslinked to undamaged DNA sampling A:T base pair IC2 | Descriptor: | 5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*TP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*CP*G*TP*CP*CP*AP*AP*GP*TP*CP*TP*AP*CP*C)-3', ZINC ION, ... | Authors: | Banerjee, A, Santos, W.L, Verdine, G.L. | Deposit date: | 2005-11-26 | Release date: | 2006-03-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of a DNA glycosylase searching for lesions. Science, 311, 2006
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2F5Q
| Catalytically inactive (E3Q) MutM crosslinked to oxoG:C containing DNA CC2 | Descriptor: | 5'-D(*AP*GP*G*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*CP*G*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3', ZINC ION, ... | Authors: | Banerjee, A, Santos, W.L, Verdine, G.L. | Deposit date: | 2005-11-26 | Release date: | 2006-03-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure of a DNA glycosylase searching for lesions. Science, 311, 2006
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2F5S
| Catalytically inactive (E3Q) MutM crosslinked to oxoG:C containing DNA CC1 | Descriptor: | 5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*C*GP*TP*CP*CP*(8OG)P*AP*GP*TP*CP*TP*AP*CP*C)-3', ZINC ION, ... | Authors: | Banerjee, A, Santos, W.L, Verdine, G.L. | Deposit date: | 2005-11-26 | Release date: | 2006-03-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure of a DNA glycosylase searching for lesions. Science, 311, 2006
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2OPF
| Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli (R252A) in complex with AP-site containing DNA substrate | Descriptor: | 5'-D(*GP*GP*CP*TP*TP*CP*AP*TP*CP*CP*TP*G)-3', 5'-D(P*CP*AP*GP*GP*AP*(PED)P*GP*AP*AP*GP*CP*C)-3', Endonuclease VIII, ... | Authors: | Golan, G, Zharov, D.O, Grollman, A.P, Shoham, G. | Deposit date: | 2007-01-29 | Release date: | 2008-02-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Active site plasticity of endonuclease VIII: Conformational changes compensating for different substrates and mutations of critical residues To be Published
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2OQ4
| Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli (E2Q) in complex with AP-site containing DNA substrate | Descriptor: | 5'-D(*C*CP*AP*GP*GP*AP*(PED)P*GP*AP*AP*GP*CP*C)-3', 5'-D(*G*GP*CP*TP*TP*CP*AP*TP*CP*CP*TP*GP*G)-3', Endonuclease VIII, ... | Authors: | Golan, G, Zharkov, D.O, Grollman, A.P, Shoahm, G. | Deposit date: | 2007-01-31 | Release date: | 2008-02-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Active site plasticity of endonuclease VIII: Conformational changes compensating for different substrates and mutations of critical residues To be Published
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2XZF
| CRYSTAL STRUCTURE OF A COMPLEX BETWEEN THE WILD-TYPE LACTOCOCCUS LACTIS FPG (MUTM) AND AN OXIDIZED PYRIMIDINE CONTAINING DNA AT 293K | Descriptor: | 5'-D(*CP*TP*CP*TP*TP*TP*VETP*TP*TP*TP*CP*TP*CP*GP)-3', 5'-D(*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*AP*GP*CP)-3', FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE, ... | Authors: | LeBihan, Y.V, Izquierdo, M.A, Coste, F, Culard, F, Gehrke, T.H, Essalhi, K, Aller, P, Carrel, T, Castaing, B. | Deposit date: | 2010-11-25 | Release date: | 2011-10-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.799 Å) | Cite: | 5-Hydroxy-5-Methylhydantoin DNA Lesion, a Molecular Trap for DNA Glycosylases Nucleic Acids Res., 39, 2011
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2XZU
| CRYSTAL STRUCTURE OF A COMPLEX BETWEEN THE WILD-TYPE LACTOCOCCUS LACTIS FPG (MUTM) AND AN OXIDIZED PYRIMIDINE CONTAINING DNA AT 310K | Descriptor: | 5'-D(*CP*TP*CP*TP*TP*TP*VETP*TP*TP*TP*CP*TP*CP*G)-3', 5'-D(GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*G*A)-3', FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE, ... | Authors: | Lebihan, Y.V, Izquierdo, M.A, Coste, F, Culard, F, Gehrke, T.H, Essalhi, K, Aller, P, Carrel, T, Castaing, B. | Deposit date: | 2010-11-29 | Release date: | 2011-10-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | 5-Hydroxy-5-Methylhydantoin DNA Lesion, a Molecular Trap for DNA Glycosylases Nucleic Acids Res., 39, 2011
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3C58
| Crystal structure of a complex between the wild-type lactococcus lactis Fpg (MutM) and a N7-Benzyl-Fapy-dG containing DNA | Descriptor: | DNA (5'-D(*DCP*DTP*DCP*DTP*DTP*DTP*(SOS)P*DTP*DTP*DTP*DCP*DTP*DCP*DG)-3'), DNA (5'-D(*DGP*DCP*DGP*DAP*DGP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DGP*DA)-3'), DNA glycosylase, ... | Authors: | Coste, F, Castaing, B, Carell, T. | Deposit date: | 2008-01-31 | Release date: | 2008-12-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Bacterial base excision repair enzyme Fpg recognizes bulky N7-substituted-FapydG lesion via unproductive binding mode Chem.Biol., 15, 2008
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3GO8
| MutM encountering an intrahelical 8-oxoguanine (oxoG) lesion in EC3-loop deletion complex | Descriptor: | 5'-D(*GP*CP*GP*TP*CP*CP*(8OG)P*GP*AP*TP*CP*TP*AP*C)-3', 5'-D(P*GP*GP*TP*AP*GP*AP*TP*CP*CP*GP*GP*AP*CP*G)-3', Formamidopyrimidine-DNA glycosylase, ... | Authors: | Spong, M.C, Qi, Y, Verdine, G.L. | Deposit date: | 2009-03-18 | Release date: | 2009-12-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme Nature, 462, 2009
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3GP1
| MutM encountering an intrahelical 8-oxoguanine (oxoG) lesion in EC3-V222P complex | Descriptor: | 5'-D(*AP*GP*GP*TP*AP*GP*AP*TP*CP*CP*GP*GP*AP*CP*GP*CP**C)-3', 5'-D(P*TP*GP*CP*GP*TP*CP*CP*(8OG)P*GP*AP*TP*CP*TP*AP*CP*C)-3', DNA glycosylase, ... | Authors: | Spong, M.C, Qi, Y, Verdine, G.L. | Deposit date: | 2009-03-20 | Release date: | 2009-11-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme Nature, 462, 2009
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3GPP
| MutM encountering an intrahelical 8-oxoguanine (oxoG) lesion in EC3-T224P complex | Descriptor: | DNA (5'-D(P*CP*GP*TP*CP*CP*(8OG)P*GP*AP*TP*CP*TP*AP*C)-3'), DNA (5'-D(P*GP*GP*TP*AP*GP*AP*TP*CP*CP*GP*GP*AP*C)-3'), DNA glycosylase, ... | Authors: | Spong, M.C, Qi, Y, Verdine, G.L. | Deposit date: | 2009-03-23 | Release date: | 2009-11-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme. Nature, 462, 2009
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3GPU
| MutM encountering an intrahelical 8-oxoguanine (oxoG) lesion in EC4-loop deletion complex | Descriptor: | DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*(8OG)P*AP*GP*TP*CP*TP*AP*CP*C)-3'), DNA glycosylase, ... | Authors: | Banerjee, A, Qi, Y, Verdine, G.L. | Deposit date: | 2009-03-23 | Release date: | 2009-11-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme. Nature, 462, 2009
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3GPX
| Sequence-matched MutM Interrogation Complex 4 (IC4) | Descriptor: | DNA (5'-D(*A*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*GP*AP*GP*TP*CP*TP*AP*CP*C)-3'), DNA glycosylase, ... | Authors: | Spong, M.C, Qi, Y, Verdine, G.L. | Deposit date: | 2009-03-23 | Release date: | 2009-11-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme. Nature, 462, 2009
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3GPY
| Sequence-matched MutM Lesion Recognition Complex 3 (LRC3) | Descriptor: | DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*TP*CP*CP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*T*GP*CP*GP*TP*CP*CP*(8OG)P*GP*AP*TP*CP*TP*AP*CP*C)-3'), DNA glycosylase, ... | Authors: | Qi, Y, Verdine, G.L. | Deposit date: | 2009-03-23 | Release date: | 2009-11-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme. Nature, 462, 2009
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3GQ3
| MutM encountering an intrahelical 8-oxoguanine (oxoG) lesion in EC5-loop deletion complex | Descriptor: | DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*CP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*GP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3'), DNA glycosylase, ... | Authors: | Banerjee, A, Qi, Y, Verdine, G.L. | Deposit date: | 2009-03-23 | Release date: | 2009-11-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme. Nature, 462, 2009
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3GQ4
| Sequence-matched MutM Lesion Recognition Complex 5 (LRC5) | Descriptor: | DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*CP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*GP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3'), DNA glycosylase, ... | Authors: | Spong, M.C, Qi, Y, Verdine, G.L. | Deposit date: | 2009-03-23 | Release date: | 2009-11-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme. Nature, 462, 2009
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3GQ5
| Sequence-matched MutM Interrogation Complex 5 (IC5) | Descriptor: | DNA (5'-D(*A*GP*GP*TP*AP*GP*AP*CP*CP*CP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*T*CP*CP*GP*GP*GP*TP*CP*TP*AP*CP*C)-3'), DNA glycosylase, ... | Authors: | Qi, Y, Verdine, G.L. | Deposit date: | 2009-03-23 | Release date: | 2009-11-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme. Nature, 462, 2009
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3JR4
| MutM interrogating an extrahelical G | Descriptor: | DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*G*CP*GP*TP*CP*CP*AP*(GX1)P*GP*TP*CP*TP*AP*CP*C)-3'), DNA glycosylase, ... | Authors: | Qi, Y, Spong, M.C, Verdine, G.L. | Deposit date: | 2009-09-08 | Release date: | 2009-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Entrapment and structure of an extrahelical guanine attempting to enter the active site of a bacterial DNA glycosylase, MutM. J.Biol.Chem., 285, 2010
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3JR5
| MutM lesion recognition control complex with N174C crosslinking site | Descriptor: | DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*(OGX)P*AP*GP*TP*CP*TP*AP*CP*C)-3'), DNA glycosylase, ... | Authors: | Qi, Y, Spong, M.C, Verdine, G.L. | Deposit date: | 2009-09-08 | Release date: | 2009-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.704 Å) | Cite: | Entrapment and structure of an extrahelical guanine attempting to enter the active site of a bacterial DNA glycosylase, MutM. J.Biol.Chem., 285, 2010
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3SAR
| MUTM Slanted complex 1 | Descriptor: | 5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*C*GP*TP*CP*CP*AP*GP*GP*TP*(CX2) P*TP*AP*CP*C)-3', Formamidopyrimidine-DNA glycosylase, ... | Authors: | Banerjee, A, Qi, Y, Spong, M.C, Verdine, G.L. | Deposit date: | 2011-06-03 | Release date: | 2012-01-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Strandwise translocation of a DNA glycosylase on undamaged DNA. Proc.Natl.Acad.Sci.USA, 109, 2012
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3SAS
| MUTM Slanted complex 4 with R112A mutation | Descriptor: | 5'-D(*A*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3', 5'-D(*T*GP*CP*GP*TP*CP*CP*GP*AP*GP*(TX2) P*CP*TP*AP*CP*C)-3', DNA GLYCOSYLASE, ... | Authors: | Qi, Y, Verdine, G.L. | Deposit date: | 2011-06-03 | Release date: | 2012-01-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Strandwise translocation of a DNA glycosylase on undamaged DNA. Proc.Natl.Acad.Sci.USA, 109, 2012
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3SAT
| MUTM Slanted complex 6 with R112A mutation | Descriptor: | 5'-D(*AP*GP*G*TP*AP*GP*AP*CP*CP*AP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*T*CP*CP*TP*GP*GP*(TX2) P*CP*TP*AP*CP*C)-3', DNA GLYCOSYLASE, ... | Authors: | Qi, Y, Verdine, G.L. | Deposit date: | 2011-06-03 | Release date: | 2012-01-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Strandwise translocation of a DNA glycosylase on undamaged DNA. Proc.Natl.Acad.Sci.USA, 109, 2012
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3SAU
| MUTM Interrogation complex 6 | Descriptor: | 5'-D(*A*GP*GP*TP*AP*GP*AP*CP*CP*AP*GP*GP*AP*CP*GP*C)-3', 5'-D(*TP*GP*CP*GP*T*CP*CP*TP*GP*GP*(TX2) P*CP*TP*AP*CP*C)-3', DNA GLYCOSYLASE, ... | Authors: | Spong, M.C, Qi, Y, Verdine, G.L. | Deposit date: | 2011-06-03 | Release date: | 2012-01-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Strandwise translocation of a DNA glycosylase on undamaged DNA. Proc.Natl.Acad.Sci.USA, 109, 2012
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3SAV
| MUTM Slanted complex 8 | Descriptor: | DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*AP*AP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*T*CP*CP*TP*TP*GP*TP*(CX2)P*TP*AP*CP*C)-3'), DNA GLYCOSYLASE, ... | Authors: | Spong, M.C, Qi, Y, Verdine, G.L. | Deposit date: | 2011-06-03 | Release date: | 2012-01-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.125 Å) | Cite: | Strandwise translocation of a DNA glycosylase on undamaged DNA. Proc.Natl.Acad.Sci.USA, 109, 2012
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