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1EF4
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BU of 1ef4 by Molmil
SOLUTION STRUCTURE OF THE ESSENTIAL RNA POLYMERASE SUBUNIT RPB10 FROM METHANOBACTERIUM THERMOAUTOTROPHICUM
Descriptor: DNA-DIRECTED RNA POLYMERASE, ZINC ION
Authors:Mackereth, C.D, Arrowsmith, C.H, Edwards, A.M, Mcintosh, L.P, Northeast Structural Genomics Consortium (NESG)
Deposit date:2000-02-07
Release date:2000-06-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Zinc-bundle structure of the essential RNA polymerase subunit RPB10 from Methanobacterium thermoautotrophicum.
Proc.Natl.Acad.Sci.USA, 97, 2000
1ONV
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BU of 1onv by Molmil
NMR Structure of a Complex Containing the TFIIF Subunit RAP74 and the RNAP II CTD Phosphatase FCP1
Descriptor: Transcription initiation factor IIF, alpha subunit, serine phosphatase FCP1a
Authors:Nguyen, B.D, Abbott, K.L, Potempa, K, Kobor, M.S, Archambault, J, Greenblatt, J, Legault, P, Omichinski, J.G.
Deposit date:2003-03-02
Release date:2003-05-20
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR Structure of a Complex Containing the TFIIF Subunit RAP74 and the RNA polymerase II carboxyl-terminal domain phosphatase FCP1
Proc.Natl.Acad.Sci.USA, 100, 2003
1IW7
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BU of 1iw7 by Molmil
Crystal structure of the RNA polymerase holoenzyme from Thermus thermophilus at 2.6A resolution
Descriptor: LEAD (II) ION, MAGNESIUM ION, RNA polymerase alpha subunit, ...
Authors:RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2002-04-22
Release date:2002-06-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of a bacterial RNA polymerase holoenzyme at 2.6 A resolution
NATURE, 417, 2002
4B02
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BU of 4b02 by Molmil
The C-terminal Priming Domain is Strongly Associated with the Main Body of Bacteriophage phi6 RNA-Dependent RNA Polymerase
Descriptor: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE
Authors:Sarin, L.P, Wright, S, Chen, Q, Degerth, L.H, Stuart, D.I, Grimes, J.M, Bamford, D.H, Poranen, M.M.
Deposit date:2012-06-27
Release date:2012-08-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The C-Terminal Priming Domain is Strongly Associated with the Main Body of Bacteriophage Phi6 RNA-Dependent RNA Polymerase.
Virology, 432, 2012
3NFG
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BU of 3nfg by Molmil
Crystal structure of Dimerization module of RNA polymerase I subcomplex A49/A34.5
Descriptor: DNA-directed RNA polymerase I subunit RPA34, DNA-directed RNA polymerase I subunit RPA49
Authors:Geiger, S.R.
Deposit date:2010-06-10
Release date:2010-09-08
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex.
Mol.Cell, 39, 2010
3NFH
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BU of 3nfh by Molmil
Crystal structure of tandem winged helix domain of RNA polymerase I subunit A49 (P4)
Descriptor: DNA-directed RNA polymerase I subunit RPA49
Authors:Geiger, S.R, Lorenzen, K, Schreieck, A, Hanecker, P, Kostrewa, D, Heck, A.J.R, Cramer, P.
Deposit date:2010-06-10
Release date:2010-09-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex.
Mol.Cell, 39, 2010
3NFI
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BU of 3nfi by Molmil
Crystal structure of tandem winged helix domain of RNA polymerase I subunit A49
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DNA-directed RNA polymerase I subunit RPA49
Authors:Geiger, S.R, Lorenzen, K, Schreieck, A, Hanecker, P, Kostrewa, D, Heck, A.J.R, Cramer, P.
Deposit date:2010-06-10
Release date:2010-09-08
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex.
Mol.Cell, 39, 2010
4NC8
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BU of 4nc8 by Molmil
N-terminal domain of delta-subunit of RNA polymerase complexed with nickel ions
Descriptor: DNA-directed RNA polymerase subunit delta, NICKEL (II) ION
Authors:Demo, G, Papouskova, V, Komarek, J, Sanderova, H, Rabatinova, A, Krasny, L, Zidek, L, Sklenar, V, Wimmerova, M.
Deposit date:2013-10-24
Release date:2014-07-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:X-ray vs. NMR structure of N-terminal domain of delta-subunit of RNA polymerase.
J.Struct.Biol., 187, 2014
4NC7
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BU of 4nc7 by Molmil
N-terminal domain of delta-subunit of RNA polymerase complexed with I3C and nickel ions
Descriptor: 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, DNA-directed RNA polymerase subunit delta, NICKEL (II) ION
Authors:Demo, G, Papouskova, V, Komarek, J, Sanderova, H, Rabatinova, A, Krasny, L, Zidek, L, Sklenar, V, Wimmerova, M.
Deposit date:2013-10-24
Release date:2014-07-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray vs. NMR structure of N-terminal domain of delta-subunit of RNA polymerase.
J.Struct.Biol., 187, 2014
7RIL
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BU of 7ril by Molmil
Crystal structure of hairpin polyamide Py-Im 1 bound to 5' CCTGACCAGG
Descriptor: 3-({3-[(3-{[4-({4-[(4-{[4-({(2R)-2-amino-4-[(1-methyl-4-{[1-methyl-4-({1-methyl-4-[(1-methyl-1H-imidazole-2-carbonyl)amino]-1H-imidazole-2-carbonyl}amino)-1H-pyrrole-2-carbonyl]amino}-1H-pyrrole-2-carbonyl)amino]butanoyl}amino)-1-methyl-1H-imidazole-2-carbonyl]amino}-1-methyl-1H-pyrrole-2-carbonyl)amino]-1-methyl-1H-pyrrole-2-carbonyl}amino)-1-methyl-1H-pyrrole-2-carbonyl]amino}propyl)(methyl)amino]propyl}carbamoyl)benzoic acid, ACETATE ION, non-template DNA, ...
Authors:Oh, J, Dervan, P.B, Wang, D.
Deposit date:2021-07-20
Release date:2022-01-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:RNA polymerase II trapped on a molecular treadmill: Structural basis of persistent transcriptional arrest by a minor groove DNA binder.
Proc.Natl.Acad.Sci.USA, 119, 2022
4QJF
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BU of 4qjf by Molmil
X-ray crystal structure of Thermocuccus kodakarensis RNA polymerase Rpp4/Rpo7 (RpoF/RpoE) complex
Descriptor: DNA-directed RNA polymerase, subunit E', subunit F
Authors:Murakami, K.S.
Deposit date:2014-06-03
Release date:2014-10-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.312 Å)
Cite:Crystal structure of euryarchaeal RNA polymerase and insight into the evolution of RNA polymerase II structure
Nat.Commun., 2014
1GX6
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BU of 1gx6 by Molmil
Hepatitis C Virus RNA polymerase in complex with UTP and manganese
Descriptor: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE, URIDINE 5'-TRIPHOSPHATE
Authors:Bressanelli, S, Rey, F.A.
Deposit date:2002-03-27
Release date:2002-04-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with Ribonucleotides
J.Virol., 76, 2002
1GX5
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BU of 1gx5 by Molmil
Hepatitis C Virus RNA Polymerase in Complex with GTP and Manganese
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE
Authors:Bressanelli, S, Rey, F.A.
Deposit date:2002-03-27
Release date:2002-04-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with Ribonucleotides
J.Virol., 76, 2002
3CJ2
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BU of 3cj2 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
Descriptor: 4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
Authors:Kissinger, c.
Deposit date:2008-03-12
Release date:2008-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3CJ3
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BU of 3cj3 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
Descriptor: 4-bromo-2-{[(2R)-2-(2-chlorobenzyl)pyrrolidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
Authors:Kissinger, c.
Deposit date:2008-03-12
Release date:2008-04-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3CJ4
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BU of 3cj4 by Molmil
Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
Descriptor: 4-[(4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}phenyl)amino]-4-oxobutanoic acid, NICKEL (II) ION, RNA-directed RNA polymerase
Authors:Antonysamy, s.s.
Deposit date:2008-03-12
Release date:2008-04-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
8BYQ
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BU of 8byq by Molmil
RNA polymerase II pre-initiation complex with the proximal +1 nucleosome (PIC-Nuc10W)
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
Deposit date:2022-12-14
Release date:2023-05-03
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
8BVW
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BU of 8bvw by Molmil
RNA polymerase II pre-initiation complex with the distal +1 nucleosome (PIC-Nuc18W)
Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ...
Authors:Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
Deposit date:2022-12-20
Release date:2023-05-03
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
7NKX
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BU of 7nkx by Molmil
RNA polymerase II-Spt4/5-nucleosome-Chd1 structure
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromatin elongation factor SPT4, ...
Authors:Farnung, L, Ochmann, M, Engeholm, M, Cramer, P.
Deposit date:2021-02-19
Release date:2021-08-25
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of nucleosome transcription mediated by Chd1 and FACT.
Nat.Struct.Mol.Biol., 28, 2021
8BZ1
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BU of 8bz1 by Molmil
RNA polymerase II core pre-initiation complex with the proximal +1 nucleosome (cPIC-Nuc10W)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB11-a, ...
Authors:Abril-Garrido, J, Dienemann, C, Grabbe, F, Velychko, T, Lidschreiber, M, Wang, H, Cramer, P.
Deposit date:2022-12-14
Release date:2023-05-03
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Mol.Cell, 83, 2023
2E2H
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BU of 2e2h by Molmil
RNA polymerase II elongation complex at 5 mM Mg2+ with GTP
Descriptor: 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ...
Authors:Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D.
Deposit date:2006-11-14
Release date:2006-12-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.95 Å)
Cite:Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
2E2I
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BU of 2e2i by Molmil
RNA polymerase II elongation complex in 5 mM Mg+2 with 2'-dGTP
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', ...
Authors:Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D.
Deposit date:2006-11-14
Release date:2006-12-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
2E2J
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BU of 2e2j by Molmil
RNA polymerase II elongation complex in 5 mM Mg+2 with GMPCPP
Descriptor: 27-MER DNA template strand, 5'-D(P*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*A)-3', 5'-R(P*AP*UP*CP*GP*AP*GP*AP*GP*G)-3', ...
Authors:Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D.
Deposit date:2006-11-14
Release date:2006-12-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
3S16
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BU of 3s16 by Molmil
RNA Polymerase II Initiation Complex with an 8-nt RNA
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-14
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.241 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011
3S14
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RNA Polymerase II Initiation Complex with a 6-nt RNA
Descriptor: DNA (5'-D(*CP*TP*AP*CP*CP*GP*AP*TP*AP*AP*GP*CP*AP*GP*AP*CP*GP*AP*TP*CP*CP*TP*CP*TP*CP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ...
Authors:Liu, X, Bushnell, D.A, Silva, D.A, Huang, X, Kornberg, R.D.
Deposit date:2011-05-14
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Initiation complex structure and promoter proofreading.
Science, 333, 2011

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數據於2024-07-10公開中

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