1NJS
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![BU of 1njs by Molmil](/molmil-images/mine/1njs) | human GAR Tfase in complex with hydrolyzed form of 10-trifluoroacetyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid | Descriptor: | N-{4-[(1R)-4-[(2R,4R,5S)-2,4-DIAMINO-6-OXOHEXAHYDROPYRIMIDIN-5-YL]-1-(2,2,2-TRIFLUORO-1,1-DIHYDROXYETHYL)BUTYL]BENZOYL}-D-GLUTAMIC ACID, PHOSPHATE ION, Phosphoribosylglycinamide formyltransferase | Authors: | Zhang, Y, Desharnais, J, Marsilje, T.H, Li, C, Hedrick, M.P, Gooljarsingh, L.T, Tavassoli, A, Benkovic, S.J, Olson, A.J, Boger, D.L, Wilson, I.A. | Deposit date: | 2003-01-02 | Release date: | 2003-06-10 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Rational Design, Synthesis, Evaluation, and Crystal Structure of a Potent Inhibitor of Human GAR Tfase: 10-(Trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic Acid Biochemistry, 42, 2003
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1NH8
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![BU of 1nh8 by Molmil](/molmil-images/mine/1nh8) | ATP PHOSPHORIBOSYLTRANSFERASE (ATP-PRTASE) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH AMP AND HISTIDINE | Descriptor: | ADENOSINE MONOPHOSPHATE, ATP Phosphoribosyltransferase, HISTIDINE, ... | Authors: | Cho, Y, Sharma, V, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2002-12-18 | Release date: | 2003-02-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of ATP phosphoribosyltransferase from Mycobacterium tuberculosis J.Biol.Chem., 278, 2003
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2BNI
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![BU of 2bni by Molmil](/molmil-images/mine/2bni) | pLI mutant E20C L16G Y17H, antiparallel | Descriptor: | GENERAL CONTROL PROTEIN GCN4 | Authors: | Yadav, M.K, Leman, L.J, Stout, C.D, Ghadiri, M.R. | Deposit date: | 2005-03-24 | Release date: | 2005-03-30 | Last modified: | 2019-05-08 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure-Based Engineering of Internal Cavities in Coiled-Coil Peptides Biochemistry, 44, 2005
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2ZGO
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![BU of 2zgo by Molmil](/molmil-images/mine/2zgo) | Crystal structure of AAL mutant H59Q complex with lactose | Descriptor: | Anti-tumor lectin, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Li, D.F, Yang, N, Wang, D.C. | Deposit date: | 2008-01-23 | Release date: | 2009-01-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the tumor cell apoptosis-inducing activity of an antitumor lectin from the edible mushroom Agrocybe aegerita J.Mol.Biol., 387, 2009
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1KGP
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![BU of 1kgp by Molmil](/molmil-images/mine/1kgp) | R2F from Corynebacterium Ammoniagenes in its Mn substituted form | Descriptor: | MANGANESE (II) ION, Ribonucleotide reductase protein R2F | Authors: | Hogbom, M, Huque, Y, Sjoberg, B.M, Nordlund, P. | Deposit date: | 2001-11-28 | Release date: | 2001-12-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the di-iron/radical protein of ribonucleotide reductase from Corynebacterium ammoniagenes. Biochemistry, 41, 2002
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1KJ9
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![BU of 1kj9 by Molmil](/molmil-images/mine/1kj9) | Crystal structure of purt-encoded glycinamide ribonucleotide transformylase complexed with Mg-ATP | Descriptor: | 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Thoden, J.B, Firestine, S.M, Benkovic, S.J, Holden, H.M. | Deposit date: | 2001-12-04 | Release date: | 2002-06-28 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | PurT-encoded glycinamide ribonucleotide transformylase. Accommodation of adenosine nucleotide analogs within the active site. J.Biol.Chem., 277, 2002
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2ZGP
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![BU of 2zgp by Molmil](/molmil-images/mine/2zgp) | |
1KSZ
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![BU of 1ksz by Molmil](/molmil-images/mine/1ksz) | ENTRAPMENT OF 6-THIOPHOSPHORYL-IMP IN THE ACTIVE SITE OF CRYSTALLINE ADENYLOSUCCINATE SYNTHETASE FROM ESCHERICHIA COLI, DATA COLLECTED AT 298K | Descriptor: | 2-DEAZO-6-THIOPHOSPHATE GUANOSINE-5'-MONOPHOSPHATE, ADENYLOSUCCINATE SYNTHETASE, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Poland, B.W, Bruns, C.A, Fromm, H.J, Honzatko, R.B. | Deposit date: | 1997-01-14 | Release date: | 1997-10-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Entrapment of 6-thiophosphoryl-IMP in the active site of crystalline adenylosuccinate synthetase from Escherichia coli. J.Biol.Chem., 272, 1997
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1HYB
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![BU of 1hyb by Molmil](/molmil-images/mine/1hyb) | CRYSTAL STRUCTURE OF AN ACTIVE SITE MUTANT OF METHANOBACTERIUM THERMOAUTOTROPHICUM NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE | Descriptor: | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE, SULFATE ION | Authors: | Saridakis, V, Christendat, D, Kimber, M.S, Edwards, A.M, Pai, E.F. | Deposit date: | 2001-01-18 | Release date: | 2001-03-14 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insights into ligand binding and catalysis of a central step in NAD+ synthesis: structures of Methanobacterium thermoautotrophicum NMN adenylyltransferase complexes. J.Biol.Chem., 276, 2001
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2ZGL
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1HOP
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![BU of 1hop by Molmil](/molmil-images/mine/1hop) | STRUCTURE OF GUANINE NUCLEOTIDE (GPPCP) COMPLEX OF ADENYLOSUCCINATE SYNTHETASE FROM ESCHERICHIA COLI AT PH 6.5 AND 25 DEGREES CELSIUS | Descriptor: | ADENYLOSUCCINATE SYNTHETASE, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | Authors: | Poland, B.W, Hou, Z, Bruns, C, Fromm, H.J, Honzatko, R.B. | Deposit date: | 1996-04-26 | Release date: | 1996-11-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Refined crystal structures of guanine nucleotide complexes of adenylosuccinate synthetase from Escherichia coli. J.Biol.Chem., 271, 1996
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1KJ8
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![BU of 1kj8 by Molmil](/molmil-images/mine/1kj8) | Crystal Structure of PurT-Encoded Glycinamide Ribonucleotide Transformylase in Complex with Mg-ATP and GAR | Descriptor: | 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Thoden, J.B, Firestine, S.M, Benkovic, S.J, Holden, H.M. | Deposit date: | 2001-12-04 | Release date: | 2002-06-28 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | PurT-encoded glycinamide ribonucleotide transformylase. Accommodation of adenosine nucleotide analogs within the active site. J.Biol.Chem., 277, 2002
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1HOO
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![BU of 1hoo by Molmil](/molmil-images/mine/1hoo) | STRUCTURE OF GUANINE NUCLEOTIDE (GPPCP) COMPLEX OF ADENYLOSUCCINATE SYNTHETASE FROM E. COLI AT PH 6.5 AND 25 DEGREES CELSIUS | Descriptor: | ADENYLOSUCCINATE SYNTHETASE, AMINOPHOSPHONIC ACID-GUANYLATE ESTER, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | Authors: | Poland, B.W, Hou, Z, Bruns, C, Fromm, H.J, Honzatko, R.B. | Deposit date: | 1996-04-26 | Release date: | 1997-02-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Refined crystal structures of guanine nucleotide complexes of adenylosuccinate synthetase from Escherichia coli. J.Biol.Chem., 271, 1996
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4PYA
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![BU of 4pya by Molmil](/molmil-images/mine/4pya) | MoaC K51A in complex with 3',8-cH2GTP | Descriptor: | (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate, 1,2-ETHANEDIOL, Molybdenum cofactor biosynthesis protein MoaC | Authors: | Tonthat, N.K, Hover, B.M, Yokoyama, K, Schumacher, M.A. | Deposit date: | 2014-03-26 | Release date: | 2015-04-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.789 Å) | Cite: | Mechanism of pyranopterin ring formation in molybdenum cofactor biosynthesis. Proc.Natl.Acad.Sci.USA, 112, 2015
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1HV9
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1NX6
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![BU of 1nx6 by Molmil](/molmil-images/mine/1nx6) | |
1FAP
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![BU of 1fap by Molmil](/molmil-images/mine/1fap) | THE STRUCTURE OF THE IMMUNOPHILIN-IMMUNOSUPPRESSANT FKBP12-RAPAMYCIN COMPLEX INTERACTING WITH HUMAN FRAP | Descriptor: | FK506-BINDING PROTEIN, FRAP, RAPAMYCIN IMMUNOSUPPRESSANT DRUG | Authors: | Choi, J, Chen, J, Schreiber, S.L, Clardy, J. | Deposit date: | 1996-03-15 | Release date: | 1997-07-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP. Science, 273, 1996
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2W6P
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1J4H
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![BU of 1j4h by Molmil](/molmil-images/mine/1j4h) | crystal structure analysis of the FKBP12 complexed with 000107 small molecule | Descriptor: | 3-PHENYL-2-{[4-(TOLUENE-4-SULFONYL)-THIOMORPHOLINE-3-CARBONYL]-AMINO}-PROPIONIC ACID ETHYL ESTER, FKBP12 | Authors: | Li, P, Ding, Y, Wang, L, Wu, B, Shu, C, Li, S, Shen, B, Rao, Z. | Deposit date: | 2001-09-30 | Release date: | 2003-06-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Design and structure-based study of new potential FKBP12 inhibitors. Biophys.J., 85, 2003
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1IXP
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![BU of 1ixp by Molmil](/molmil-images/mine/1ixp) | Enzyme-phosphate Complex of Pyridoxine 5'-Phosphate synthase | Descriptor: | PHOSPHATE ION, Pyridoxine 5'-Phosphate synthase | Authors: | Garrido-Franco, M, Laber, B, Huber, R, Clausen, T. | Deposit date: | 2002-06-28 | Release date: | 2003-02-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis J.MOL.BIOL., 321, 2002
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4PYD
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![BU of 4pyd by Molmil](/molmil-images/mine/4pyd) | MoaC in complex with cPMP crystallized in space group P212121 | Descriptor: | (2R,4AR,5AR,11AR,12AS)-8-AMINO-2-HYDROXY-4A,5A,9,11,11A,12A-HEXAHYDRO[1,3,2]DIOXAPHOSPHININO[4',5':5,6]PYRANO[3,2-G]PTERIDINE-10,12(4H,6H)-DIONE 2-OXIDE, 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... | Authors: | Tonthat, N.K, Hover, B.M, Yokoyama, K, Schumacher, M.A. | Deposit date: | 2014-03-26 | Release date: | 2015-04-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.186 Å) | Cite: | Mechanism of pyranopterin ring formation in molybdenum cofactor biosynthesis. Proc.Natl.Acad.Sci.USA, 112, 2015
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1MAS
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![BU of 1mas by Molmil](/molmil-images/mine/1mas) | PURINE NUCLEOSIDE HYDROLASE | Descriptor: | INOSINE-URIDINE NUCLEOSIDE N-RIBOHYDROLASE, POTASSIUM ION | Authors: | Degano, M, Gopaul, D.N, Scapin, G, Schramm, V.L, Sacchettini, J.C. | Deposit date: | 1995-12-18 | Release date: | 1996-08-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Three-dimensional structure of the inosine-uridine nucleoside N-ribohydrolase from Crithidia fasciculata. Biochemistry, 35, 1996
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1NWC
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![BU of 1nwc by Molmil](/molmil-images/mine/1nwc) | |
1ZGK
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![BU of 1zgk by Molmil](/molmil-images/mine/1zgk) | 1.35 angstrom structure of the Kelch domain of Keap1 | Descriptor: | Kelch-like ECH-associated protein 1 | Authors: | Li, X, Bottoms, C.A, Hannink, M, Beamer, L.J. | Deposit date: | 2005-04-21 | Release date: | 2005-10-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Conserved solvent and side-chain interactions in the 1.35 Angstrom structure of the Kelch domain of Keap1. Acta Crystallogr.,Sect.D, 61, 2005
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1GIM
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![BU of 1gim by Molmil](/molmil-images/mine/1gim) | CRYSTAL STRUCTURE OF ADENYLOSUCCINATE SYNTHETASE FROM ESCHERICHIA COLI COMPLEXED WITH GDP, IMP, HADACIDIN, NO3-, AND MG2+. DATA COLLECTED AT 100K (PH 6.5) | Descriptor: | ADENYLOSUCCINATE SYNTHETASE, GUANOSINE-5'-DIPHOSPHATE, HADACIDIN, ... | Authors: | Poland, B.W, Fromm, H.J, Honzatko, R.B. | Deposit date: | 1996-06-15 | Release date: | 1996-12-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of adenylosuccinate synthetase from Escherichia coli complexed with GDP, IMP hadacidin, NO3-, and Mg2+. J.Mol.Biol., 264, 1996
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