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2RFJ
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Crystal structure of the bromo domain 1 in human bromodomain containing protein, testis specific (BRDT)
Descriptor: Bromodomain testis-specific protein
Authors:Filippakopoulos, P, Salah, E, Savitsky, P, Keates, T, Parizotto, E, Elkins, J, Pike, A.C.W, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Sundstrom, M, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2007-09-30
Release date:2007-10-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
2R87
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BU of 2r87 by Molmil
Crystal structure of PurP from Pyrococcus furiosus complexed with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, PurP protein PF1517
Authors:Zhang, Y, White, R.H, Ealick, S.E.
Deposit date:2007-09-10
Release date:2007-12-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure and function of 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase from Methanocaldococcus jannaschii.
Biochemistry, 47, 2008
3QA2
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BU of 3qa2 by Molmil
X-ray Structure of ketohexokinase in complex with a pyrimidopyrimidine analog 2
Descriptor: Ketohexokinase, N~8~-(cyclopropylmethyl)-N~4~-(2-methylphenyl)-2-(piperazin-1-yl)pyrimido[5,4-d]pyrimidine-4,8-diamine, SULFATE ION
Authors:Abad, M.C.
Deposit date:2011-01-10
Release date:2012-01-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.519 Å)
Cite:Inhibitors of Ketohexokinase: Discovery of Pyrimidinopyrimidines with Specific Substitution that Complements the ATP-Binding Site.
ACS Med Chem Lett, 2, 2011
2RLC
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BU of 2rlc by Molmil
Crystal Structure of the Conjugated Bile Acid Hydrolase from Clostridium perfringens in Complex with Reaction Products Glycine and Cholate
Descriptor: CHOLIC ACID, Choloylglycine hydrolase, GLYCINE, ...
Authors:Rossmann, M, Saenger, W.
Deposit date:2007-10-18
Release date:2009-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of choloyl glycine hydrolase from Clostridium perfringens
To be Published
2REJ
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BU of 2rej by Molmil
ABC-transporter choline binding protein in unliganded semi-closed conformation
Descriptor: PUTATIVE GLYCINE BETAINE ABC TRANSPORTER PROTEIN
Authors:Oswald, C, Smits, S.H.J, Hoeing, M, Sohn-Boeser, L, Le Rudulier, D, Schmitt, L, Bremer, E.
Deposit date:2007-09-26
Release date:2008-09-16
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of the choline/acetylcholine substrate-binding protein ChoX from Sinorhizobium meliloti in the liganded and unliganded-closed states.
J.Biol.Chem., 283, 2008
3QSB
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BU of 3qsb by Molmil
Structure of E. coli polIIIbeta with (Z)-5-(1-((4'-Fluorobiphenyl-4-yl)methoxyimino)butyl)-2,2-dimethyl-4,6-dioxocyclohexanecarbonitrile
Descriptor: (1R,5R)-5-{(1Z)-N-[(4'-fluorobiphenyl-4-yl)methoxy]butanimidoyl}-2,2-dimethyl-4,6-dioxocyclohexanecarbonitrile, DNA polymerase III subunit beta
Authors:Wijffels, G, Johnson, W.M, Oakley, A.J, Turner, K, Epa, V.C, Briscoe, S.J, Polley, M, Liepa, A.J, Hofmann, A, Buchardt, J, Christensen, C, Prosselkov, P, Dalrymple, B.P, Alewood, P.F, Jennings, P.A, Dixon, N.E, Winkler, D.A.
Deposit date:2011-02-20
Release date:2011-06-08
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Binding inhibitors of the bacterial sliding clamp by design
J.Med.Chem., 54, 2011
3QFE
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BU of 3qfe by Molmil
Crystal structures of a putative dihydrodipicolinate synthase family protein from Coccidioides immitis
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-01-21
Release date:2011-02-02
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structures of a putative dihydrodipicolinate synthase family protein from Coccidioides immitis
To be Published
2RDE
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BU of 2rde by Molmil
Crystal structure of VCA0042 complexed with c-di-GMP
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Uncharacterized protein VCA0042
Authors:Benach, J, Swaminathan, S.S, Tamayo, R, Seetharaman, J, Handelman, S, Forouhar, F, Neely, H, Camilli, A, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2007-09-22
Release date:2007-10-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:The structural basis of cyclic diguanylate signal transduction by PilZ domains.
Embo J., 26, 2007
3EJJ
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BU of 3ejj by Molmil
Structure of M-CSF bound to the first three domains of FMS
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Colony stimulating factor-1, Macrophage colony-stimulating factor 1 receptor
Authors:Chen, X, Liu, H, Focia, P.J, Shim, A, He, X.
Deposit date:2008-09-18
Release date:2008-12-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of macrophage colony stimulating factor bound to FMS: diverse signaling assemblies of class III receptor tyrosine kinases.
Proc.Natl.Acad.Sci.USA, 105, 2008
2REG
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BU of 2reg by Molmil
ABC-transporter choline binding protein in complex with choline
Descriptor: CHOLINE ION, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN
Authors:Oswald, C, Schimtt, L, Smits, S.H.J, Hoeing, M, Sohn-Boeser, L, Bremer, E.
Deposit date:2007-09-26
Release date:2008-09-16
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of the choline/acetylcholine substrate-binding protein ChoX from Sinorhizobium meliloti in the liganded and unliganded-closed states.
J.Biol.Chem., 283, 2008
3QI4
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BU of 3qi4 by Molmil
Crystal structure of PDE9A(Q453E) in complex with IBMX
Descriptor: 3-ISOBUTYL-1-METHYLXANTHINE, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ...
Authors:Hou, J, Xu, J, Liu, M, Zhao, R, Lou, H, Ke, H.
Deposit date:2011-01-26
Release date:2011-04-27
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural asymmetry of phosphodiesterase-9, potential protonation of a glutamic Acid, and role of the invariant glutamine.
Plos One, 6, 2011
3QK7
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BU of 3qk7 by Molmil
Crystal structure of putative Transcriptional regulator from Yersinia pestis biovar Microtus str. 91001
Descriptor: Transcriptional regulators
Authors:Malashkevich, V.N, Toro, R, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2011-01-31
Release date:2011-02-09
Last modified:2021-02-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of putative Transcriptional regulator from Yersinia pestis biovar Microtus str. 91001
To be Published
3QJP
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BU of 3qjp by Molmil
An RAMP protein binding different RNA substrates
Descriptor: Putative uncharacterized protein PH0350, RNA (5'-R(P*UP*AP*GP*UP*UP*UP*AP*A)-3')
Authors:Wang, R, Zheng, H, Preamplume, G, Li, H.
Deposit date:2011-01-30
Release date:2012-02-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.2986 Å)
Cite:Cooperative and Specific Binding of a RAMP Protein to Single-stranded CRISPR Repeat RNA
To be Published
3EKC
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BU of 3ekc by Molmil
structure of W60V beta-2 microglobulin mutant
Descriptor: Beta-2-microglobulin
Authors:Ricagno, S, Sangiovanni, E, Bellotti, V, Bolognesi, M.
Deposit date:2008-09-19
Release date:2009-05-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Human beta-2 microglobulin W60V mutant structure: Implications for stability and amyloid aggregation
Biochem.Biophys.Res.Commun., 380, 2009
3EPE
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BU of 3epe by Molmil
Crystal Structure of the GluR4 Ligand-Binding domain in complex with glutamate
Descriptor: GLUTAMIC ACID, Glutamate receptor 4,Glutamate receptor
Authors:Gill, A, Madden, D.R.
Deposit date:2008-09-29
Release date:2009-05-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Correlating AMPA receptor activation and cleft closure across subunits: crystal structures of the GluR4 ligand-binding domain in complex with full and partial agonists
Biochemistry, 47, 2008
3QMP
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BU of 3qmp by Molmil
Selenium SAD structure solution of proteinase K grown in SO4-less solution and soaked in selenate.
Descriptor: CALCIUM ION, GLYCEROL, Proteinase K, ...
Authors:Jakoncic, J.
Deposit date:2011-02-04
Release date:2012-01-18
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystallization of macromolecules in selenate to solve the phase problem
To be Published
3ELK
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BU of 3elk by Molmil
Crystal structure of putative transcriptional regulator TA0346 from Thermoplasma acidophilum
Descriptor: CHLORIDE ION, Putative transcriptional regulator TA0346
Authors:Grantz Saskova, K, Chruszcz, M, Evdokimova, E, Egorova, O, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG)
Deposit date:2008-09-22
Release date:2008-09-30
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of putative transcriptional regulator TA0346 from Thermoplasma acidophilum
To be Published
2RKB
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BU of 2rkb by Molmil
Serine dehydratase like-1 from human cancer cells
Descriptor: POTASSIUM ION, PYRIDOXAL-5'-PHOSPHATE, Serine dehydratase-like
Authors:Yamada, T, Komoto, J, Kasuya, T, Mori, H, Ogawa, H, Takusagawa, F.
Deposit date:2007-10-16
Release date:2008-04-01
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A catalytic mechanism that explains a low catalytic activity of serine dehydratase like-1 from human cancer cells: Crystal structure and site-directed mutagenesis studies.
Biochim.Biophys.Acta, 1780, 2008
3QO1
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BU of 3qo1 by Molmil
Monoclinic form of IgG1 Fab fragment (apo form) sharing same Fv as IgA
Descriptor: Fab fragment of IMMUNOGLOBULIN G1 HEAVY CHAIN, Fab fragment of IMMUNOGLOBULIN G1 LIGHT CHAIN, GLYCEROL
Authors:Trajtenberg, F, Correa, A, Buschiazzo, A.
Deposit date:2011-02-09
Release date:2012-02-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of a human IgA1 Fab fragment at 1.55 angstrom resolution: potential effect of the constant domains on antigen-affinity modulation
Acta Crystallogr.,Sect.D, 69, 2013
3QUA
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BU of 3qua by Molmil
Crystal structure of a putative uncharacterized protein and possible Molybdenum cofactor protein from Mycobacterium smegmatis
Descriptor: Putative uncharacterized protein, UNKNOWN LIGAND
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-02-23
Release date:2011-03-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
2RB9
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BU of 2rb9 by Molmil
Crystal structure of E.coli HypE
Descriptor: HypE protein
Authors:Asinas, A.E, Rangarajan, E.S, Min, T, Matte, A, Proteau, A, Munger, C, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2007-09-18
Release date:2007-10-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of [NiFe] hydrogenase maturation protein HypE from Escherichia coli and its interaction with HypF.
J.Bacteriol., 190, 2008
3QRE
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BU of 3qre by Molmil
Crystal structure of an enoyl-coA hydratase EchA12_1 from Mycobacterium marinum
Descriptor: CHLORIDE ION, Enoyl-CoA hydratase, EchA12_1, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-02-17
Release date:2011-03-02
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3EY3
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BU of 3ey3 by Molmil
A Conformational Transition in the Structure of a 2'-Thiomethyl-Modified DNA Visualized at High Resolution
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 5'-D(*CP*GP*CP*GP*AP*AP*(USM)P*(USM)P*CP*GP*CP*G)-3', STRONTIUM ION
Authors:Egli, M, Pallan, P.S.
Deposit date:2008-10-17
Release date:2009-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:A conformational transition in the structure of a 2'-thiomethyl-modified DNA visualized at high resolution.
Chem.Commun.(Camb.), 15, 2009
3QRS
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BU of 3qrs by Molmil
HIV-1 protease (mutant Q7K L33I L63I) in complex with a three-armed pyrrolidine-based inhibitor
Descriptor: 4-({(3S,4S)-4-[(4-carbamoylbenzyl)amino]pyrrolidin-3-yl}[4-(trifluoromethyl)benzyl]sulfamoyl)benzamide, CHLORIDE ION, Protease
Authors:Lindemann, I, Heine, A, Klebe, G.
Deposit date:2011-02-18
Release date:2012-02-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Design of a series of novel three-armed pyrrolidine-based inhibitors for HIV-1 protease
To be Published
2RFA
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BU of 2rfa by Molmil
Crystal structure of the mouse TRPV6 ankyrin repeat domain
Descriptor: Transient receptor potential cation channel subfamily V member 6
Authors:Phelps, C.B, Huang, R.J, Wang, R.R, Gaudet, R.
Deposit date:2007-09-28
Release date:2008-02-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural analyses of the ankyrin repeat domain of TRPV6 and related TRPV ion channels.
Biochemistry, 47, 2008

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數據於2024-09-04公開中

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