8GY3
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![BU of 8gy3 by Molmil](/molmil-images/mine/8gy3) | Cryo-EM Structure of Membrane-Bound Aldehyde Dehydrogenase from Gluconobacter oxydans | Descriptor: | (MOLYBDOPTERIN-CYTOSINE DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V), Cytochrome c subunit of aldehyde dehydrogenase, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Adachi, T, Miyata, T, Makino, F, Tanaka, H, Namba, K, Sowa, K, Kitazumi, Y, Shirai, O. | Deposit date: | 2022-09-21 | Release date: | 2023-08-02 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Experimental and Theoretical Insights into Bienzymatic Cascade for Mediatorless Bioelectrochemical Ethanol Oxidation with Alcohol and Aldehyde Dehydrogenases Acs Catalysis, 13, 2023
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8GY2
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![BU of 8gy2 by Molmil](/molmil-images/mine/8gy2) | Cryo-EM Structure of Membrane-Bound Alcohol Dehydrogenase from Gluconobacter oxydans | Descriptor: | Alcohol dehydrogenase (quinone), cytochrome c subunit, dehydrogenase subunit, ... | Authors: | Adachi, T, Miyata, T, Makino, F, Tanaka, H, Namba, K, Sowa, K, Kitazumi, Y, Shirai, O. | Deposit date: | 2022-09-21 | Release date: | 2023-08-02 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Experimental and Theoretical Insights into Bienzymatic Cascade for Mediatorless Bioelectrochemical Ethanol Oxidation with Alcohol and Aldehyde Dehydrogenases Acs Catalysis, 13, 2023
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8GY1
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8GXZ
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![BU of 8gxz by Molmil](/molmil-images/mine/8gxz) | 1 sulfate and 1 ATP bound V1EG of V/A-ATPase from Thermus thermophilus. | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, SULFATE ION, ... | Authors: | Nakanishi, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K. | Deposit date: | 2022-09-21 | Release date: | 2023-01-25 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM analysis of V/A-ATPase intermediates reveals the transition of the ground-state structure to steady-state structures by sequential ATP binding. J.Biol.Chem., 299, 2023
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8GXY
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![BU of 8gxy by Molmil](/molmil-images/mine/8gxy) | 2 sulfate-bound V1EG of V/A-ATPase from Thermus thermophilus. | Descriptor: | SULFATE ION, V-type ATP synthase alpha chain, V-type ATP synthase beta chain, ... | Authors: | Nakanishi, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K. | Deposit date: | 2022-09-21 | Release date: | 2023-01-25 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Cryo-EM analysis of V/A-ATPase intermediates reveals the transition of the ground-state structure to steady-state structures by sequential ATP binding. J.Biol.Chem., 299, 2023
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8GXX
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![BU of 8gxx by Molmil](/molmil-images/mine/8gxx) | 3 nucleotide-bound V1EG of V/A-ATPase from Thermus thermophilus. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Nakanishi, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K. | Deposit date: | 2022-09-21 | Release date: | 2023-01-25 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cryo-EM analysis of V/A-ATPase intermediates reveals the transition of the ground-state structure to steady-state structures by sequential ATP binding. J.Biol.Chem., 299, 2023
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8GXW
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![BU of 8gxw by Molmil](/molmil-images/mine/8gxw) | 2 ATP-bound V1EG of V/A-ATPase from Thermus thermophilus | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, SULFATE ION, ... | Authors: | Nakanishi, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K. | Deposit date: | 2022-09-21 | Release date: | 2023-01-25 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Cryo-EM analysis of V/A-ATPase intermediates reveals the transition of the ground-state structure to steady-state structures by sequential ATP binding. J.Biol.Chem., 299, 2023
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8GXV
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8GXU
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![BU of 8gxu by Molmil](/molmil-images/mine/8gxu) | 1 ATP-bound V1EG of V/A-ATPase from Thermus thermophilus | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, SULFATE ION, V-type ATP synthase alpha chain, ... | Authors: | Nakanishi, A, Kishikawa, J, Mitsuoka, K, Yokoyama, K. | Deposit date: | 2022-09-21 | Release date: | 2023-01-25 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Cryo-EM analysis of V/A-ATPase intermediates reveals the transition of the ground-state structure to steady-state structures by sequential ATP binding. J.Biol.Chem., 299, 2023
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8GXS
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![BU of 8gxs by Molmil](/molmil-images/mine/8gxs) | PIC-Mediator in complex with +1 nucleosome (T40N) in H-binding state | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | Authors: | Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X. | Deposit date: | 2022-09-21 | Release date: | 2022-11-02 | Method: | ELECTRON MICROSCOPY (4.16 Å) | Cite: | Structures of +1 nucleosome-bound PIC-Mediator complex. Science, 378, 2022
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8GXQ
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![BU of 8gxq by Molmil](/molmil-images/mine/8gxq) | PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | Authors: | Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X, Xu, Y. | Deposit date: | 2022-09-21 | Release date: | 2022-11-02 | Method: | ELECTRON MICROSCOPY (5.04 Å) | Cite: | Structures of +1 nucleosome-bound PIC-Mediator complex. Science, 378, 2022
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8GXP
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![BU of 8gxp by Molmil](/molmil-images/mine/8gxp) | Complex structure of RORgama with betulinic acid | Descriptor: | Betulinic acid, Nuclear receptor ROR-gamma | Authors: | Zhang, X.L, Xu, C, Bai, F. | Deposit date: | 2022-09-20 | Release date: | 2023-06-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR gamma antagonists. Eur.J.Med.Chem., 257, 2023
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8GXO
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8GXK
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![BU of 8gxk by Molmil](/molmil-images/mine/8gxk) | Pseudomonas jinjuensis N-acetyltransferase | Descriptor: | COENZYME A, Protein N-acetyltransferase, RimJ/RimL family | Authors: | Song, Y.J, Bao, R. | Deposit date: | 2022-09-20 | Release date: | 2022-10-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | The novel type II toxin-antitoxin PacTA modulates Pseudomonas aeruginosa iron homeostasis by obstructing the DNA-binding activity of Fur. Nucleic Acids Res., 50, 2022
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8GXJ
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8GXI
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![BU of 8gxi by Molmil](/molmil-images/mine/8gxi) | The crystal structure of SARS-CoV-2 main protease in complex with 14c | Descriptor: | 3C-like proteinase nsp5, N-[(2S)-3-cyclohexyl-1-[[(2S,3R)-4-(cyclopropylamino)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]butan-2-yl]amino]-1-oxidanylidene-propan-2-yl]-1-benzofuran-2-carboxamide | Authors: | Zhao, Y, Zhao, J, Shao, M, Yang, H, Rao, Z. | Deposit date: | 2022-09-20 | Release date: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | The crystal structure of SARS-CoV-2 main protease in complex with 14c To Be Published
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8GXH
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![BU of 8gxh by Molmil](/molmil-images/mine/8gxh) | The crystal structure of SARS-CoV-2 main protease in complex with 14b | Descriptor: | 3C-like proteinase nsp5, N-[(2S)-3-cyclohexyl-1-oxidanylidene-1-[[(2S,3R)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-1-benzofuran-2-carboxamide | Authors: | Zhao, Y, Zhao, J, Shao, M, Yang, H, Rao, Z. | Deposit date: | 2022-09-20 | Release date: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | The crystal structure of SARS-CoV-2 main protease in complex with 14b To Be Published
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8GXG
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![BU of 8gxg by Molmil](/molmil-images/mine/8gxg) | The crystal structure of SARS-CoV-2 main protease in complex with 14a | Descriptor: | 3C-like proteinase nsp5, N-[(2S)-3-(4-fluorophenyl)-1-oxidanylidene-1-[[(2S,3S)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-1-benzofuran-2-carboxamide | Authors: | Zhao, Y, Zhao, J, Shao, M, Yang, H, Rao, Z. | Deposit date: | 2022-09-20 | Release date: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | The crystal structure of SARS-CoV-2 main protease in complex with 14a To Be Published
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8GXF
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![BU of 8gxf by Molmil](/molmil-images/mine/8gxf) | Pseudomonas flexibilis GCN5 family acetyltransferase | Descriptor: | COENZYME A, GCN5 family acetyltransferase | Authors: | Song, Y.J, Bao, R. | Deposit date: | 2022-09-20 | Release date: | 2022-10-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.04 Å) | Cite: | The novel type II toxin-antitoxin PacTA modulates Pseudomonas aeruginosa iron homeostasis by obstructing the DNA-binding activity of Fur. Nucleic Acids Res., 50, 2022
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8GXD
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![BU of 8gxd by Molmil](/molmil-images/mine/8gxd) | L-LEUCINE DEHYDROGENASE FROM EXIGUOBACTERIUM SIBIRICUM | Descriptor: | CALCIUM ION, GLYCEROL, Glu/Leu/Phe/Val dehydrogenase | Authors: | Mu, X, Nie, Y, Wu, T, Wang, Y, Zhang, N, Yin, D, Xu, Y. | Deposit date: | 2022-09-19 | Release date: | 2023-04-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.02 Å) | Cite: | Reshaping Substrate-Binding Pocket of Leucine Dehydrogenase for Bidirectionally Accessing Structurally Diverse Substrates Acs Catalysis, 13, 2023
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8GX4
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8GX3
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![BU of 8gx3 by Molmil](/molmil-images/mine/8gx3) | The crystal structure of human Calpain-1 protease core in complex with 14c | Descriptor: | CALCIUM ION, Calpain-1 catalytic subunit, N-[(2S)-3-cyclohexyl-1-[[(2S,3S)-4-(cyclopropylamino)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]butan-2-yl]amino]-1-oxidanylidene-propan-2-yl]-1-benzofuran-2-carboxamide | Authors: | Zhao, Y, Zhao, J, Shao, M, Yang, H, Rao, Z. | Deposit date: | 2022-09-18 | Release date: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | The crystal structure of human Calpain-1 protease core in complex with 14c To Be Published
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8GX2
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![BU of 8gx2 by Molmil](/molmil-images/mine/8gx2) | The crystal structure of human CtsL in complex with 14c | Descriptor: | DIMETHYL SULFOXIDE, N-[(2S)-3-cyclohexyl-1-[[(2S,3S)-4-(cyclopropylamino)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepiperidin-3-yl]butan-2-yl]amino]-1-oxidanylidene-propan-2-yl]-1-benzofuran-2-carboxamide, Procathepsin L | Authors: | Zhao, Y, Shao, M, Zhao, J, Yang, H, Rao, Z. | Deposit date: | 2022-09-18 | Release date: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structure of human CtsL in complex with 14a To Be Published
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8GWN
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![BU of 8gwn by Molmil](/molmil-images/mine/8gwn) | A mechanism for SARS-CoV-2 RNA capping and its inhibitor of AT-527 | Descriptor: | Helicase, Non-structural protein 7, Non-structural protein 8, ... | Authors: | Yan, L.M, Huang, Y.C, Ge, J, Liu, Z.Y, Gao, Y, Rao, Z.H, Lou, Z.Y. | Deposit date: | 2022-09-17 | Release date: | 2022-12-14 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
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8GWE
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![BU of 8gwe by Molmil](/molmil-images/mine/8gwe) | SARS-CoV-2 E-RTC complex with RNA-nsp9 and GMPPNP | Descriptor: | Helicase nsp13, MAGNESIUM ION, Non-structural protein 8, ... | Authors: | Yan, L.M, Rao, Z.H, Lou, Z.Y. | Deposit date: | 2022-09-16 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
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