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5VHA
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DHX36 with an N-terminal truncation
Descriptor: DEAH (Asp-Glu-Ala-His) box polypeptide 36
Authors:Chen, M, Ferre-D'Amare, A.
Deposit date:2017-04-12
Release date:2018-06-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.227 Å)
Cite:Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36.
Nature, 558, 2018
5VHC
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BU of 5vhc by Molmil
DHX36 with an N-terminal truncation bound to ADP-BeF3
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DEAH (Asp-Glu-Ala-His) box polypeptide 36, ...
Authors:Chen, M, Ferre-D'Amare, A.
Deposit date:2017-04-12
Release date:2018-06-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36.
Nature, 558, 2018
1U64
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BU of 1u64 by Molmil
The Solution Structure of d(G3T4G4)2
Descriptor: 5'-D(*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3'
Authors:Sket, P, Crnugelj, M, Plavec, J.
Deposit date:2004-07-29
Release date:2004-10-26
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:d(G3T4G4) forms unusual dimeric G-quadruplex structure with the same general fold in the presence of K+, Na+ or NH4+ ions.
Bioorg.Med.Chem., 12, 2004
4WO3
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BU of 4wo3 by Molmil
THE SECOND C-KIT DNA QUADRUPLEX CRYSTAL STRUCTURE
Descriptor: DNA (5'-D(*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*CP*TP*GP*GP*GP*AP*GP*GP*AP*GP*GP*G)-3'), POTASSIUM ION
Authors:Wei, D, Neidle, S.
Deposit date:2014-10-15
Release date:2014-10-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:THE SECOND C-KIT1 DNA QUADRUPLEX CRYSTAL STRUCTURE
TO BE PUBLISHED
4KZE
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BU of 4kze by Molmil
Crystal structure of an RNA aptamer in complex with Fab
Descriptor: BL3-6 Fab antibody, heavy chain, light chain, ...
Authors:Huang, H, Suslov, N.B, Li, N, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A.
Deposit date:2013-05-29
Release date:2014-06-18
Last modified:2014-07-30
Method:X-RAY DIFFRACTION (2.404 Å)
Cite:A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
4KZD
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BU of 4kzd by Molmil
Crystal structure of an RNA aptamer in complex with fluorophore and Fab
Descriptor: 4-(3,5-difluoro-4-hydroxybenzyl)-1,2-dimethyl-1H-imidazol-5-ol, BL3-6 Fab antibody, heavy chain, ...
Authors:Huang, H, Suslov, N.B, Li, N, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A.
Deposit date:2013-05-29
Release date:2014-06-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.186 Å)
Cite:A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
4Q9Q
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BU of 4q9q by Molmil
Crystal structure of an RNA aptamer bound to bromo-ligand analog in complex with Fab
Descriptor: (5Z)-5-(3-bromobenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, Fab BL3-6, HEAVY CHAIN, ...
Authors:Huang, H, Suslov, N.B, Li, N.-S, Shelke, S.A, Evans, M.E, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A.
Deposit date:2014-05-01
Release date:2014-06-18
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
4Q9R
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Crystal structure of an RNA aptamer bound to trifluoroethyl-ligand analog in complex with Fab
Descriptor: (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one, Fab BL3-6, HEAVY CHAIN, ...
Authors:Huang, H, Suslov, N.B, Li, N.-S, Shelke, S.A, Evans, M.E, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A.
Deposit date:2014-05-01
Release date:2014-06-18
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
2A5R
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BU of 2a5r by Molmil
Complex of tetra-(4-n-methylpyridyl) porphin with monomeric parallel-stranded DNA tetraplex, snap-back 3+1 3' G-tetrad, single-residue chain reversal loops, GAG triad in the context of GAAG diagonal loop, C-MYC promoter, NMR, 6 struct.
Descriptor: (1Z,4Z,9Z,15Z)-5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,23-dihydroporphyrin, 5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*IP*GP*AP*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*GP*G)-3'
Authors:Phan, A.T, Kuryavyi, V.V, Gaw, H.Y, Patel, D.J.
Deposit date:2005-06-30
Release date:2005-07-26
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter.
Nat.Chem.Biol., 1, 2005
2A5P
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BU of 2a5p by Molmil
Monomeric parallel-stranded DNA tetraplex with snap-back 3+1 3' G-tetrad, single-residue chain reversal loops, GAG triad in the context of GAAG diagonal loop, NMR, 8 struct.
Descriptor: 5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*IP*GP*AP*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*GP*G)-3'
Authors:Phan, A.T, Kuryavyi, V.V, Gaw, H.Y, Patel, D.J.
Deposit date:2005-06-30
Release date:2005-07-26
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter.
Nat.Chem.Biol., 1, 2005
2WCT
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BU of 2wct by Molmil
human SARS coronavirus unique domain (triclinic form)
Descriptor: NON-STRUCTURAL PROTEIN 3
Authors:Tan, J, Vonrhein, C, Smart, O.S, Bricogne, G, Bollati, M, Hansen, G, Mesters, J.R, Hilgenfeld, R.
Deposit date:2009-03-16
Release date:2009-05-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:The Sars-Unique Domain (Sud) of Sars Coronavirus Contains Two Macrodomains that Bind G-Quadruplexes.
Plos Pathog., 5, 2009
1X0F
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BU of 1x0f by Molmil
Complex structure of the C-terminal RNA-binding domain of hnRNP D(AUF1) with telomeric DNA
Descriptor: 5'-D(P*TP*AP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein D0
Authors:Enokizono, Y, Konishi, Y, Nagata, K, Ouhashi, K, Uesugi, S, Ishikawa, F, Katahira, M.
Deposit date:2005-03-22
Release date:2005-04-05
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of hnRNP D complexed with single-stranded telomere DNA and unfolding of the quadruplex by heterogeneous nuclear ribonucleoprotein D.
J.Biol.Chem., 280, 2005
7VF1
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BU of 7vf1 by Molmil
Solution structure of a duplex-quadruplex hybrid formed by d[G4C2] repeats
Descriptor: DNA (14-mer)
Authors:Maity, A, Lim, K.W, Shneider, N.A, Chen, G, Phan, A.T.
Deposit date:2021-09-10
Release date:2022-09-14
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A duplex-quadruplex hybrid formed by d[G4C2] repeats
To be published
7W0X
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BU of 7w0x by Molmil
Tetrameric antiparallel G-quadruplex formed by natural human telomeric sequence
Descriptor: DNA (5'-D(*GP*GP*GP*TP*TP*A)-3')
Authors:Jing, H.T, Fu, W.Q.
Deposit date:2021-11-18
Release date:2022-01-19
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR structure of an alternating antiparallel tetrameric G-quadruplex assembled by the single-repeat of human telomeric DNA d(GGGTTA)
To Be Published
4KI2
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BU of 4ki2 by Molmil
Crystallographic analysis of an RNA-polymerase sigma-subunit fragment complexed with -10 promoter element ssDNA
Descriptor: DNA (5'-D(*TP*GP*TP*AP*CP*AP*AP*TP*GP*GP*G)-3'), POTASSIUM ION, RNA polymerase sigma factor
Authors:Feklistov, A, Darst, S.A.
Deposit date:2013-05-01
Release date:2013-09-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystallographic analysis of an RNA polymerase sigma-subunit fragment complexed with -10 promoter element ssDNA: quadruplex formation as a possible tool for engineering crystal contacts in protein-ssDNA complexes.
Acta Crystallogr.,Sect.F, 69, 2013
4WO2
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BU of 4wo2 by Molmil
CRYSTAL STRUCTURE OF HUMAN NATIVE CKIT PROTO-ONCOGENE PROMOTER QUADRUPLEX DNA
Descriptor: DNA (5'-D(*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*CP*TP*GP*GP*GP*AP*GP*GP*AP*GP*GP*G)-3'), POTASSIUM ION
Authors:wei, D, parkinson, g.n, neidle, s.
Deposit date:2014-10-15
Release date:2014-10-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:CRYSTAL STRUCTURE OF HUMAN NATIVE CKIT-1 PROTO-ONCOGENE PROMOTER QUADRUPLEX DNA
TO BE PUBLISHED
1LVS
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BU of 1lvs by Molmil
THE SOLUTION STRUCTURE OF D(G4T4G3)2
Descriptor: 5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*G)-3'
Authors:Crnugelj, M, Hud, N.V, Plavec, J.
Deposit date:2002-05-29
Release date:2002-07-24
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The solution structure of d(G(4)T(4)G(3))(2): a bimolecular G-quadruplex with a novel fold.
J.Mol.Biol., 320, 2002
1KF1
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BU of 1kf1 by Molmil
Structure and Packing of Human Telomeric DNA
Descriptor: 5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3, POTASSIUM ION
Authors:Parkinson, G.N, Lee, M.P.H, Neidle, S.
Deposit date:2001-11-19
Release date:2002-05-31
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of parallel quadruplexes from human telomeric DNA.
Nature, 417, 2002
1WTB
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BU of 1wtb by Molmil
Complex structure of the C-terminal RNA-binding domain of hnRNP D (AUF1) with telomere DNA
Descriptor: 5'-D(P*TP*AP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein D0
Authors:Enokizono, Y, Konishi, Y, Nagata, K, Ouhashi, K, Uesugi, S, Ishikawa, F, Katahira, M.
Deposit date:2004-11-22
Release date:2005-04-05
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of hnRNP D complexed with single-stranded telomere DNA and unfolding of the quadruplex by heterogeneous nuclear ribonucleoprotein D
J.Biol.Chem., 280, 2005
7Q48
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BU of 7q48 by Molmil
Solution structure of an intramolecular RNA G-quadruplex formed by the 6A8U17U mutant from a 22mer guanine-rich sequence within the 5'UTR of BCL-2 proto onco-gene
Descriptor: RNA (5'-R(*GP*GP*GP*CP*CP*AP*UP*UP*GP*GP*GP*UP*GP*GP*GP*AP*UP*CP*UP*GP*GP*G)-3')
Authors:Wang, Z, Jurt, S, Dominguez-Martin, A, Johannsen, S, Sigel, R.K.O.
Deposit date:2021-10-29
Release date:2022-11-16
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Solution structure of an intramolecular RNA G-quadruplex formed by the 6A8U17U mutant from a 22mer guanine-rich sequence within the 5'UTR of BCL-2 proto onco-gene
To Be Published
7Q6L
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BU of 7q6l by Molmil
Solution structure of an intramolecular RNA G-quadruplex formed by the 6A8A17U mutant from a 22mer guanine-rich sequence within the 5'UTR of BCL-2 proto-oncogene
Descriptor: RNA (5'-R(*GP*GP*GP*CP*CP*AP*UP*AP*GP*GP*GP*UP*GP*GP*GP*AP*UP*CP*UP*GP*GP*G)-3')
Authors:Wang, Z, Jurt, S, Dominguez-Martin, A, Johannsen, S, Sigel, R.K.O.
Deposit date:2021-11-08
Release date:2022-11-16
Last modified:2024-01-31
Method:SOLUTION NMR
Cite:Solution structure of an intramolecular RNA G-quadruplex formed by the 6A8A17U mutant from a 22mer guanine-rich sequence within the 5'UTR of BCL-2 proto-oncogene
To Be Published
7QA2
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BU of 7qa2 by Molmil
Solution structure of an intramolecular RNA G-quadruplex formed by the 6A mutant from a 22mer guanine-rich sequence within the 5'UTR of BCL-2 proto-oncogene
Descriptor: RNA (5'-R(*GP*GP*GP*CP*CP*AP*UP*GP*GP*GP*GP*UP*GP*GP*GP*AP*GP*CP*UP*GP*GP*G)-3')
Authors:Wang, Z, Falk, T, Jurt, S, Johannsen, S, Sigel, R.K.O.
Deposit date:2021-11-15
Release date:2022-11-23
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Solution structure of an intramolecular RNA G-quadruplex formed by the 6A mutant from a 22mer guanine-rich sequence within the 5'UTR of BCL-2 proto-oncogene
To Be Published
6H5R
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BU of 6h5r by Molmil
Structure of the complex of a human telomeric DNA with bis(1-butyl-3-methyl-imidazole-2-ylidene) gold(I)
Descriptor: Human Telomeric DNA, POTASSIUM ION, STRONTIUM ION, ...
Authors:Bazzicalupi, C, Gratteri, P, Papi, F.
Deposit date:2018-07-25
Release date:2019-01-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Interaction of a gold(i) dicarbene anticancer drug with human telomeric DNA G-quadruplex: solution and computationally aided X-ray diffraction analysis.
Dalton Trans, 47, 2018
5N98
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Crystal Structure of Drosophila DHX36 helicase in complex with TAGGGTTTT
Descriptor: CG9323, isoform A, DNA (5'-D(P*TP*AP*GP*GP*GP*TP*TP*TP*T)-3'), ...
Authors:Chen, W.-F, Rety, S, Guo, H.-L, Wu, W.-Q, Liu, N.-N, Liu, Q.-W, Dai, Y.-X, Xi, X.-G.
Deposit date:2017-02-24
Release date:2018-03-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.756 Å)
Cite:Molecular Mechanistic Insights into Drosophila DHX36-Mediated G-Quadruplex Unfolding: A Structure-Based Model.
Structure, 26, 2018
1V3O
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BU of 1v3o by Molmil
Crystal structure of d(GCGAGAGC): the DNA quadruplex structure split from the octaplex
Descriptor: 5'-D(*GP*(C38)P*GP*AP*GP*AP*GP*C)-3', POTASSIUM ION
Authors:Kondo, J, Umeda, S, Sunami, T, Takenaka, A.
Deposit date:2003-11-03
Release date:2004-06-08
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of a DNA octaplex with I-motif of G-quartets and its splitting into two quadruplexes suggest a folding mechanism of eight tandem repeats
Nucleic Acids Res., 32, 2004

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數據於2024-07-24公開中

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