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5QA8	OXA-48 IN COMPLEX WITH COMPOUND 4c Descriptor: 3-(4-hydroxyphenyl)benzoic acid, Beta-lactamase, CHLORIDE ION Authors: Lund, B.A, Leiros, H.K.S. Deposit date: 2017-07-11 Release date: 2018-01-10 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.5 Å) Cite: A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design. Eur J Med Chem, 145, 2018
5QAK	OXA-48 IN COMPLEX WITH COMPOUND 14 Descriptor: 1,2-ETHANEDIOL, 3-[3-(dimethylamino)phenyl]benzoic acid, Beta-lactamase, ... Authors: Lund, B.A, Leiros, H.K.S. Deposit date: 2017-07-11 Release date: 2018-01-10 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.9 Å) Cite: A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design. Eur J Med Chem, 145, 2018
5QB1	OXA-48 IN COMPLEX WITH COMPOUND 36 Descriptor: 1,2-ETHANEDIOL, 3,5-bis(3-acetamidophenyl)benzoic acid, Beta-lactamase, ... Authors: Lund, B.A, Leiros, H.K.S. Deposit date: 2017-07-11 Release date: 2018-01-10 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design. Eur J Med Chem, 145, 2018
5QA4	OXA-48 IN COMPLEX WITH COMPOUND 3a Descriptor: 1,2-ETHANEDIOL, 3-(2-methylphenyl)benzoic acid, Beta-lactamase, ... Authors: Lund, B.A. Deposit date: 2017-07-11 Release date: 2018-01-10 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.95 Å) Cite: A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design. Eur J Med Chem, 145, 2018
5QAO	OXA-48 IN COMPLEX WITH COMPOUND 19b Descriptor: 1,2-ETHANEDIOL, 3-[4-(methylsulfonylaminomethyl)phenyl]benzoic acid, Beta-lactamase, ... Authors: Lund, B.A, Leiros, H.K.S. Deposit date: 2017-07-11 Release date: 2018-01-10 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2 Å) Cite: A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design. Eur J Med Chem, 145, 2018
5QB0	OXA-48 IN COMPLEX WITH COMPOUND 35 Descriptor: 1,2-ETHANEDIOL, 3-pyridin-2-ylbenzoic acid, Beta-lactamase, ... Authors: Lund, B.A, Leiros, H.K.S. Deposit date: 2017-07-11 Release date: 2018-01-10 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.95 Å) Cite: A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design. Eur J Med Chem, 145, 2018
5QAB	OXA-48 IN COMPLEX WITH COMPOUND 6b Descriptor: 1,2-ETHANEDIOL, 3-(3-methoxyphenyl)benzoic acid, Beta-lactamase, ... Authors: Lund, B.A, Leiros, H.K.S. Deposit date: 2017-07-11 Release date: 2018-01-10 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.15 Å) Cite: A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design. Eur J Med Chem, 145, 2018
5QAN	OXA-48 IN COMPLEX WITH COMPOUND 19a Descriptor: 3-[3-(methylsulfonylaminomethyl)phenyl]benzoic acid, Beta-lactamase, CHLORIDE ION Authors: Lund, B.A, Leiros, H.K.S. Deposit date: 2017-07-11 Release date: 2018-01-10 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.3 Å) Cite: A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design. Eur J Med Chem, 145, 2018
5QB2	OXA-48 IN COMPLEX WITH COMPOUND 38 Descriptor: 1,2-ETHANEDIOL, 3-quinolin-6-yl-5-quinolin-7-yl-benzoic acid, Beta-lactamase, ... Authors: Lund, B.A, Leiros, H.K.S. Deposit date: 2017-07-11 Release date: 2018-01-10 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.75 Å) Cite: A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design. Eur J Med Chem, 145, 2018
5QAH	OXA-48 IN COMPLEX WITH COMPOUND 9b Descriptor: 1,2-ETHANEDIOL, 3-(3-methoxycarbonylphenyl)benzoic acid, Beta-lactamase, ... Authors: Lund, B.A, Leiros, H.K.S. Deposit date: 2017-07-11 Release date: 2018-01-10 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.95 Å) Cite: A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design. Eur J Med Chem, 145, 2018
5QAZ	OXA-48 IN COMPLEX WITH COMPOUND 34 Descriptor: 1,2-ETHANEDIOL, 3-(1~{H}-indol-5-yl)benzoic acid, Beta-lactamase, ... Authors: Lund, B.A, Leiros, H.K.S. Deposit date: 2017-07-11 Release date: 2018-01-10 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.2 Å) Cite: A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design. Eur J Med Chem, 145, 2018
5QA6	OXA-48 IN COMPLEX WITH COMPOUND 4a Descriptor: 1,2-ETHANEDIOL, 3-(2-hydroxyphenyl)benzoic acid, Beta-lactamase, ... Authors: Lund, B.A, Leiros, H.K.S. Deposit date: 2017-07-11 Release date: 2018-01-10 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.95 Å) Cite: A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design. Eur J Med Chem, 145, 2018
5QAS	OXA-48 IN COMPLEX WITH COMPOUND 23b Descriptor: 1,2-ETHANEDIOL, 3-[4-(2-acetamidoethyl)phenyl]benzoic acid, Beta-lactamase Authors: Lund, B.A, Leiros, H.K.S. Deposit date: 2017-07-11 Release date: 2018-01-10 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.9 Å) Cite: A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design. Eur J Med Chem, 145, 2018
5QAJ	OXA-48 IN COMPLEX WITH COMPOUND 13 Descriptor: 1,2-ETHANEDIOL, 3-(4-aminophenyl)benzoic acid, Beta-lactamase, ... Authors: Lund, B.A, Leiros, H.K.S. Deposit date: 2017-07-11 Release date: 2018-01-10 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2 Å) Cite: A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design. Eur J Med Chem, 145, 2018
5QAY	OXA-48 IN COMPLEX WITH COMPOUND 32 Descriptor: 1,2-ETHANEDIOL, 3-(1-methylpyrrol-2-yl)benzoic acid, Beta-lactamase, ... Authors: Lund, B.A, Leiros, H.K.S. Deposit date: 2017-07-11 Release date: 2018-01-10 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.7 Å) Cite: A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design. Eur J Med Chem, 145, 2018
5QA7	OXA-48 IN COMPLEX WITH COMPOUND 4b Descriptor: 1,2-ETHANEDIOL, 3-(3-hydroxyphenyl)benzoic acid, Beta-lactamase, ... Authors: Lund, B.A, Leiros, H.K.S. Deposit date: 2017-07-11 Release date: 2018-01-10 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.82 Å) Cite: A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design. Eur J Med Chem, 145, 2018
5QAP	OXA-48 IN COMPLEX WITH COMPOUND 21a Descriptor: 1,2-ETHANEDIOL, 3-(3-acetamidophenyl)benzoic acid, Beta-lactamase, ... Authors: Lund, B.A, Leiros, H.K.S. Deposit date: 2017-07-11 Release date: 2018-01-10 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.79 Å) Cite: A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design. Eur J Med Chem, 145, 2018
5QAF	OXA-48 IN COMPLEX WITH COMPOUND 8c Descriptor: 1,2-ETHANEDIOL, 3-(4-fluorophenyl)benzoic acid, Beta-lactamase, ... Authors: Lund, B.A, Leiros, H.K.S. Deposit date: 2017-07-11 Release date: 2018-01-10 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.15 Å) Cite: A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design. Eur J Med Chem, 145, 2018
5QAR	OXA-48 IN COMPLEX WITH COMPOUND 23a Descriptor: 3-[3-(2-acetamidoethyl)phenyl]benzoic acid, Beta-lactamase, CHLORIDE ION Authors: Lund, B.A, Leiros, H.K.S. Deposit date: 2017-07-11 Release date: 2018-01-10 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.1 Å) Cite: A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design. Eur J Med Chem, 145, 2018
7ZG8	Crystal structure of A. baumannii penicillin-binding protein 2 Descriptor: Peptidoglycan D,D-transpeptidase MrdA, ZINC ION Authors: Micelli, C, Crow, A, Roper, D.I. Deposit date: 2022-04-02 Release date: 2023-02-22 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.65 Å) Cite: A conserved zinc-binding site in Acinetobacter baumannii PBP2 required for elongasome-directed bacterial cell shape. Proc.Natl.Acad.Sci.USA, 120, 2023
7O4A	Crystal structure of Penicillin-Binding Protein 1 (PBP1) from Staphylococcus aureus in complex with piperacillin Descriptor: Hydrolyzed piperacillin, Penicillin-binding protein 1 Authors: Martinez Caballero, S, Hermoso, J.A. Deposit date: 2021-04-05 Release date: 2021-11-03 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.028 Å) Cite: Integrative structural biology of the penicillin-binding protein-1 from Staphylococcus aureus , an essential component of the divisome machinery. Comput Struct Biotechnol J, 19, 2021
7O49	Crystal structure of Penicillin-Binding Protein 1 (PBP1) from Staphylococcus aureus Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CADMIUM ION, CHLORIDE ION, ... Authors: Martinez Caballero, S, Hermoso, J.A. Deposit date: 2021-04-05 Release date: 2021-11-03 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.03 Å) Cite: Integrative structural biology of the penicillin-binding protein-1 from Staphylococcus aureus , an essential component of the divisome machinery. Comput Struct Biotechnol J, 19, 2021
7BN9	Crystal Structure of Bacillus subtilis Penicillin Binding Protein 3 Descriptor: Penicillin-binding protein 3 Authors: Rao, V.A, Lewis, R.J. Deposit date: 2021-01-21 Release date: 2022-03-02 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Cooperation between peptidoglycan transpeptidases and SEDS proteins in Bacillus subtilis cell division To Be Published
1RP5	PBP2x from Streptococcus pneumoniae strain 5259 with reduced susceptibility to beta-lactam antibiotics Descriptor: SULFATE ION, penicillin-binding protein 2x Authors: Pernot, L, Chesnel, L, Legouellec, A, Croize, J, Vernet, T, Dideberg, O, Dessen, A. Deposit date: 2003-12-03 Release date: 2004-02-03 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3 Å) Cite: A PBP2x from a clinical isolate of Streptococcus pneumoniae exhibits an alternative mechanism for reduction of susceptibility to beta-lactam antibiotics. J.Biol.Chem., 279, 2004
2OLV	Structural Insight Into the Transglycosylation Step Of Bacterial Cell Wall Biosynthesis : Donor Ligand Complex Descriptor: MOENOMYCIN, Penicillin-binding protein 2 Authors: Lovering, A.L, De Castro, L, Lim, D, Strynadka, N.C.J. Deposit date: 2007-01-19 Release date: 2007-03-13 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural insight into the transglycosylation step of bacterial cell-wall biosynthesis. Science, 315, 2007

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