5TG6

OXA-24/40 in Complex with Boronic Acid BA4

Summary for 5TG6

• Entry DOI: 10.2210/pdb5tg6/pdb
• Related: 5TG4 5TG5 5TG7
• Descriptor: Beta-lactamase, tert-butyl (1-hydroxy-1,3-dihydro-2,1-benzoxaborol-6-yl)carbamate, SULFATE ION, ... (5 entities in total)
• Functional Keywords: inhibitor, complex, lactamase, oxa, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Acinetobacter baumannii
• Total number of polymer chains: 1
• Total formula weight: 28176.06

Authors

Powers, R.A.,Werner, J.P.,Mitchell, J.M. (deposition date: 2016-09-27, release date: 2017-01-11, Last modification date: 2023-11-15)

• Primary citation: Werner, J.P.,Mitchell, J.M.,Taracila, M.A.,Bonomo, R.A.,Powers, R.A.; Exploring the potential of boronic acids as inhibitors of OXA-24/40 beta-lactamase.; Protein Sci., 26:515-526, 2017; PubMed: 27997706; DOI: 10.1002/pro.3100

Experimental method

X-RAY DIFFRACTION (1.78 Å)