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7JPO
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BU of 7jpo by Molmil
ORC-O1AAA: Human Origin Recognition Complex (ORC) with dynamic/unresolved ORC2 WH
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Origin recognition complex subunit 1, ...
Authors:Jaremko, M.J, Joshua-Tor, L.
Deposit date:2020-08-09
Release date:2020-09-02
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.
Elife, 9, 2020
6JPQ
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BU of 6jpq by Molmil
CryoEM structure of Abo1 hexamer - ADP complex
Descriptor: Uncharacterized AAA domain-containing protein C31G5.19
Authors:Cho, C, Jang, J, Song, J.J.
Deposit date:2019-03-27
Release date:2020-08-19
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.44 Å)
Cite:Structural basis of nucleosome assembly by the Abo1 AAA+ ATPase histone chaperone.
Nat Commun, 10, 2019
6WJN
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BU of 6wjn by Molmil
SD-like state of human 26S Proteasome with non-cleavable M1-linked hexaubiquitin and E3 ubiquitin ligase E6AP/UBE3A
Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
Authors:Chen, X, Walters, K.J.
Deposit date:2020-04-14
Release date:2020-08-05
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome.
Structure, 28, 2020
6KE6
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BU of 6ke6 by Molmil
3.4 angstrom cryo-EM structure of yeast 90S small subunit preribosome
Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ...
Authors:Du, Y, Ye, K, An, W.
Deposit date:2019-07-03
Release date:2020-08-05
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:3.4 angstrom cryo-EM structure of yeast 90S small subunit preribosome
To be published
6WJD
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BU of 6wjd by Molmil
SA-like state of human 26S Proteasome with non-cleavable M1-linked hexaubiquitin and E3 ubiquitin ligase E6AP/UBE3A
Descriptor: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
Authors:Chen, X, Walters, K.J.
Deposit date:2020-04-13
Release date:2020-08-05
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome.
Structure, 28, 2020
6PXI
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BU of 6pxi by Molmil
The crystal structure of a singly capped HslUV complex with an axial pore plug and a HslU E257Q mutation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, ATP-dependent protease subunit HslV, ...
Authors:Baytshtok, V, Grant, R.A, Sauer, R.T.
Deposit date:2019-07-26
Release date:2020-07-29
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (3.447 Å)
Cite:Heat activates the AAA+ HslUV protease by melting an axial autoinhibitory plug.
Cell Rep, 34, 2021
6PXL
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BU of 6pxl by Molmil
3.74 Angstroms resolution structure of HlsU with an axial-channel plug
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, MAGNESIUM ION, ...
Authors:Baytshtok, V, Grant, R.A, Sauer, R.T.
Deposit date:2019-07-26
Release date:2020-07-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.741 Å)
Cite:Heat activates the AAA+ HslUV protease by melting an axial autoinhibitory plug.
Cell Rep, 34, 2021
6PXK
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BU of 6pxk by Molmil
3.65 Angstroms resolution structure of HslU with an axial-channel plug
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, SULFATE ION, ...
Authors:Baytshtok, V, Grant, R.A, Sauer, R.T.
Deposit date:2019-07-26
Release date:2020-07-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.647 Å)
Cite:Heat activates the AAA+ HslUV protease by melting an axial autoinhibitory plug.
Cell Rep, 34, 2021
6KWW
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BU of 6kww by Molmil
HslU from Staphylococcus aureus
Descriptor: ATP-dependent protease ATPase subunit HslU
Authors:Ha, N.-C, Jeong, S.
Deposit date:2019-09-09
Release date:2020-07-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Cleavage-Dependent Activation of ATP-Dependent Protease HslUV from Staphylococcus aureus .
Mol.Cells, 43, 2020
6WGG
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BU of 6wgg by Molmil
Atomic model of pre-insertion mutant OCCM-DNA complex(ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation)
Descriptor: Cell division control protein 6, Cell division cycle protein CDT1, DNA (41-MER), ...
Authors:Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C.
Deposit date:2020-04-05
Release date:2020-07-15
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (8.1 Å)
Cite:Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Proc.Natl.Acad.Sci.USA, 117, 2020
6WGC
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BU of 6wgc by Molmil
Atomic model of semi-attached mutant OCCM-DNA complex (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation)
Descriptor: Cell division control protein 6, DNA (41-MER), DNA replication licensing factor MCM3, ...
Authors:Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C.
Deposit date:2020-04-05
Release date:2020-07-15
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Proc.Natl.Acad.Sci.USA, 117, 2020
6WGI
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BU of 6wgi by Molmil
Atomic model of the mutant OCCM (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) loaded on DNA at 10.5 A resolution
Descriptor: Cell division control protein 6, Cell division cycle protein CDT1, DNA (34-MER), ...
Authors:Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C.
Deposit date:2020-04-05
Release date:2020-07-15
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Proc.Natl.Acad.Sci.USA, 117, 2020
6W21
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BU of 6w21 by Molmil
ClpAP Engaged2 State bound to RepA-GFP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ...
Authors:Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R.
Deposit date:2020-03-04
Release date:2020-05-13
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis.
Nat.Struct.Mol.Biol., 27, 2020
6W1Z
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BU of 6w1z by Molmil
ClpAP Engaged1 State bound to RepA-GFP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ...
Authors:Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R.
Deposit date:2020-03-04
Release date:2020-05-06
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis.
Nat.Struct.Mol.Biol., 27, 2020
6W23
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BU of 6w23 by Molmil
ClpA Disengaged State bound to RepA-GFP (Focused Classification)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ...
Authors:Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R.
Deposit date:2020-03-04
Release date:2020-05-06
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis.
Nat.Struct.Mol.Biol., 27, 2020
6W20
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BU of 6w20 by Molmil
ClpAP Disengaged State bound to RepA-GFP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ...
Authors:Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R.
Deposit date:2020-03-04
Release date:2020-05-06
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis.
Nat.Struct.Mol.Biol., 27, 2020
6W24
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BU of 6w24 by Molmil
ClpA Engaged2 State bound to RepA-GFP (Focused Classification)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ...
Authors:Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R.
Deposit date:2020-03-04
Release date:2020-05-06
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis.
Nat.Struct.Mol.Biol., 27, 2020
6W22
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BU of 6w22 by Molmil
ClpA Engaged1 State bound to RepA-GFP (ClpA Focused Refinement)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ...
Authors:Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R.
Deposit date:2020-03-04
Release date:2020-04-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis.
Nat.Struct.Mol.Biol., 27, 2020
6UQE
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BU of 6uqe by Molmil
ClpA/ClpP Disengaged State bound to RepA-GFP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease proteolytic subunit, ...
Authors:Lopez, K.L, Rizo, A.R, Southworth, D.R.
Deposit date:2019-10-18
Release date:2020-04-22
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis.
Nat.Struct.Mol.Biol., 27, 2020
6UQO
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BU of 6uqo by Molmil
ClpA/ClpP Engaged State bound to RepA-GFP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp endopeptidase proteolytic subunit ClpP, ATP-dependent Clp protease ATP-binding subunit ClpA, ...
Authors:Lopez, K.L, Rizo, A.N, Southworth, D.R.
Deposit date:2019-10-21
Release date:2020-04-22
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis.
Nat.Struct.Mol.Biol., 27, 2020
6U5Z
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BU of 6u5z by Molmil
Cryo-EM structure of E. coli LonA S679A
Descriptor: Lon protease
Authors:Botos, I, Lountos, G.T, Weimin, W, Wlodawer, A.
Deposit date:2019-08-28
Release date:2020-02-26
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structure of substrate-free E. coli Lon protease provides insights into the dynamics of Lon machinery
Curr Res Struct Biol, 1, 2020
6VVO
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BU of 6vvo by Molmil
Structure of the human clamp loader (Replication Factor C, RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen, PCNA)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Gaubitz, C, Liu, X, Stone, N.P, Kelch, B.A.
Deposit date:2020-02-18
Release date:2020-02-26
Last modified:2020-03-25
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of the human clamp loader bound to the sliding clamp: a further twist on AAA+ mechanism
Biorxiv, 2020
6UKO
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BU of 6uko by Molmil
Structure analysis of full-length mouse bcs1 complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1
Authors:Xia, D, Esser, L.
Deposit date:2019-10-05
Release date:2020-02-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:Structures of AAA protein translocase Bcs1 suggest translocation mechanism of a folded protein.
Nat.Struct.Mol.Biol., 27, 2020
6UKP
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BU of 6ukp by Molmil
Apo mBcs1
Descriptor: Mitochondrial chaperone BCS1
Authors:Tang, W.K, Borgnia, M.J, Hsu, A.L, Xia, D.
Deposit date:2019-10-05
Release date:2020-02-12
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.81 Å)
Cite:Structures of AAA protein translocase Bcs1 suggest translocation mechanism of a folded protein.
Nat.Struct.Mol.Biol., 27, 2020
6PE0
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BU of 6pe0 by Molmil
Msp1 (E214Q)-substrate complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Membrane-spanning ATPase-like protein, ...
Authors:Wang, L, Myasnikov, A, Pan, X, Walter, P.
Deposit date:2019-06-19
Release date:2020-02-12
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction.
Elife, 9, 2020

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數據於2024-09-11公開中

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