2G43
 
 | | Structure of the ZNF UBP domain from deubiquitinating enzyme isopeptidase T (IsoT) | | Descriptor: | UNKNOWN ATOM OR ION, Ubiquitin carboxyl-terminal hydrolase 5, ZINC ION | | Authors: | Reyes-Turcu, F.E, Horton, J.R, Mullally, J.E, Heroux, A, Cheng, X, Wilkinson, K.D. | | Deposit date: | 2006-02-21 | | Release date: | 2006-04-04 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | The Ubiquitin Binding Domain ZnF UBP Recognizes the C-Terminal Diglycine Motif of Unanchored Ubiquitin.
Cell(Cambridge,Mass.), 124, 2006
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2L14
 | | Structure of CBP nuclear coactivator binding domain in complex with p53 TAD | | Descriptor: | CREB-binding protein, Cellular tumor antigen p53 | | Authors: | Lee, C, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. | | Deposit date: | 2010-07-22 | | Release date: | 2010-11-03 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structure of the p53 transactivation domain in complex with the nuclear receptor coactivator binding domain of CREB binding protein.
Biochemistry, 49, 2010
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5YWR
 | | Crystal Structure of RING E3 ligase ZNRF1 in complex with Ube2N (Ubc13) | | Descriptor: | E3 ubiquitin-protein ligase ZNRF1, FORMIC ACID, TRIETHYLENE GLYCOL, ... | | Authors: | Behera, A.P, Naskar, P, Datta, A.B. | | Deposit date: | 2017-11-30 | | Release date: | 2018-06-06 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.47 Å) | | Cite: | Structural insights into the nanomolar affinity of RING E3 ligase ZNRF1 for Ube2N and its functional implications.
Biochem. J., 475, 2018
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2LB6
 | | Structure of 18694Da MUP, typical to the major urinary protein family: MUP9, MUP11, MUP15, MUP18 & MUP19 | | Descriptor: | Major urinary protein 6 | | Authors: | Phelan, M.M, Mclean, L, Beynon, R.J, Hurst, J.L, Lian, L. | | Deposit date: | 2011-03-23 | | Release date: | 2012-03-28 | | Last modified: | 2023-12-06 | | Method: | SOLUTION NMR | | Cite: | Structural insights into the specificity of darcin, an atypical major urinary protein.
To be Published
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2LB5
 | | Refined Structural Basis for the Photoconversion of A Phytochrome to the Activated FAR-RED LIGHT-ABSORBING Form | | Descriptor: | PHYCOCYANOBILIN, Sensor histidine kinase | | Authors: | Cornilescu, C.C, Cornilescu, G, Ulijasz, A.T, Vierstra, R.D, Markley, J.L. | | Deposit date: | 2011-03-23 | | Release date: | 2011-06-29 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structural basis for the photoconversion of a phytochrome to the activated Pfr form.
Nature, 463, 2010
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2FJA
 | | adenosine 5'-phosphosulfate reductase in complex with substrate | | Descriptor: | ADENOSINE-5'-PHOSPHOSULFATE, FLAVIN-ADENINE DINUCLEOTIDE, IRON/SULFUR CLUSTER, ... | | Authors: | Schiffer, A, Fritz, G, Kroneck, P.M, Ermler, U. | | Deposit date: | 2006-01-02 | | Release date: | 2006-03-28 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Reaction mechanism of the iron-sulfur flavoenzyme adenosine-5'-phosphosulfate reductase based on the structural characterization of different enzymatic states
Biochemistry, 45, 2006
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1E6I
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2LB9
 | | Refined solution structure of a cyanobacterial phytochrome gaf domain in the red light-absorbing ground state (corrected pyrrole ring planarity) | | Descriptor: | PHYCOCYANOBILIN, Sensor histidine kinase | | Authors: | Cornilescu, C.C, Cornilescu, G, Ulijasz, A.T, Vierstra, R.D, Markley, J.L. | | Deposit date: | 2011-03-23 | | Release date: | 2011-06-29 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Solution structure of a cyanobacterial phytochrome GAF domain in the red-light-absorbing ground state.
J.Mol.Biol., 383, 2008
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4JRT
 | | Crystal structure of an A-form RNA duplex containing three GU base pairs | | Descriptor: | RNA (5'-R(P*CP*CP*UP*GP*CP*AP*CP*UP*GP*CP*CP*C)-3'), RNA (5'-R(P*GP*GP*GP*UP*GP*GP*UP*GP*CP*GP*GP*G)-3') | | Authors: | Kondo, J, Dock-Bregeon, A.C, Willkomm, D.K, Hartmann, R.K, Westhof, E. | | Deposit date: | 2013-03-21 | | Release date: | 2013-06-05 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of an A-form RNA duplex obtained by degradation of 6S RNA in a crystallization droplet
Acta Crystallogr.,Sect.F, 69, 2013
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2FUS
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4JH0
 | | Crystal structure of dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2) (DPP-IV-WT) complex with bms-767778 AKA 2-(3-(aminomethyl)-4-(2,4- dichlorophenyl)-2-methyl-5-oxo-5,7-dihydro-6h-pyrrolo[3,4- b]pyridin-6-yl)-n,n-dimethylacetamide | | Descriptor: | 2-[3-(aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl-5-oxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-N,N-dimethylacetamide, Dipeptidyl peptidase 4 | | Authors: | Klei, H.E. | | Deposit date: | 2013-03-04 | | Release date: | 2013-09-04 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Optimization of Activity, Selectivity, and Liability Profiles in 5-Oxopyrrolopyridine DPP4 Inhibitors Leading to Clinical Candidate (Sa)-2-(3-(Aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl-5-oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)-N,N-dimethylacetamide (BMS-767778).
J.Med.Chem., 56, 2013
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2LXS
 | | Allosteric communication in the KIX domain proceeds through dynamic re-packing of the hydrophobic core | | Descriptor: | CREB-binding protein, Histone-lysine N-methyltransferase MLL | | Authors: | Bruschweiler, S, Schanda, P, Konrat, R, Tollinger, M. | | Deposit date: | 2012-08-31 | | Release date: | 2013-06-12 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Allosteric communication in the KIX domain proceeds through dynamic repacking of the hydrophobic core.
Acs Chem.Biol., 8, 2013
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2LW4
 | | Solution NMR Structure of Human Transcription Elongation Factor A protein 2, Central Domain, Northeast Structural Genomics Consortium (NESG) Target HR8682B | | Descriptor: | Transcription elongation factor A protein 2 | | Authors: | Eletsky, A, Wang, D, Kohan, E, Janjua, H, Xiao, R, Acton, T.B, Everett, J.K, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2012-07-20 | | Release date: | 2012-09-19 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution NMR Structure of Human Transcription Elongation Factor A protein 2, Central Domain (CASP Target)
To be Published
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2CO9
 | | Solution structure of the HMG_box domain of thymus high mobility group box protein TOX from mouse | | Descriptor: | thymus high mobility group box protein TOX | | Authors: | Li, H, Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-05-17 | | Release date: | 2005-11-17 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the HMG_box domain of thymus high mobility group box protein TOX from mouse
To be Published
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2JL9
 | | Structural explanation for the role of Mn in the activity of phi6 RNA- dependent RNA polymerase | | Descriptor: | RNA-DIRECTED RNA POLYMERASE | | Authors: | Poranen, M.M, Salgado, P.S, Koivunen, M.R.L, Wright, S, Bamford, D.H, Stuart, D.I, Grimes, J.M. | | Deposit date: | 2008-09-05 | | Release date: | 2008-11-04 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase.
Nucleic Acids Res., 36, 2008
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2JJK
 | | FRUCTOSE-1,6-BISPHOSPHATASE(D-FRUCTOSE-1,6-BISPHOSPHATE -1- PHOSPHOHYDROLASE) (E.C.3.1.3.11) COMPLEXED WITH A DUAL BINDING AMP SITE INHIBITOR | | Descriptor: | FRUCTOSE-1,6-BISPHOSPHATASE 1, N,N'-(heptane-1,7-diyldicarbamoyl)bis(3-chlorobenzenesulfonamide) | | Authors: | Ruf, A, Joseph, C, Benz, J, Fol, B, Tetaz, T, Hebeisen, P. | | Deposit date: | 2008-04-09 | | Release date: | 2008-07-22 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Allosteric Fbpase Inhibitors Gain 10(5) Times in Potency When Simultaneously Binding Two Neighboring AMP Sites.
Bioorg.Med.Chem.Lett., 18, 2008
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4G3M
 | | Complex Structure of Bacillus subtilis RibG: The Deamination Process in Riboflavin Biosynthesis | | Descriptor: | N-(5-amino-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-5-O-phosphono-beta-D-ribofuranosylamine, Riboflavin biosynthesis protein RibD, ZINC ION, ... | | Authors: | Chen, S.C, Shen, C.Y, Yen, T.M, Yu, H.C, Chang, T.H, Lai, W.L, Liaw, S.H. | | Deposit date: | 2012-07-15 | | Release date: | 2013-02-20 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.56 Å) | | Cite: | Evolution of vitamin B(2) biosynthesis: eubacterial RibG and fungal Rib2 deaminases.
Acta Crystallogr.,Sect.D, 69, 2013
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2CTO
 | | Solution structure of the HMG box like domain from human hypothetical protein FLJ14904 | | Descriptor: | novel protein | | Authors: | Tomizawa, T, Kigawa, T, Sato, M, Koshiba, S, Inoue, M, Kamatari, Y.O, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-05-24 | | Release date: | 2005-11-24 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the HMG box like domain from human hypothetical protein FLJ14904
To be Published
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2KM4
 | | Solution structure of Rtt103 CTD interacting domain | | Descriptor: | Regulator of Ty1 transposition protein 103 | | Authors: | Lunde, B.M, Reichow, S, Kim, M, Leeper, T.C, Becker, R, Buratowski, S, Meinhart, A, Varani, G. | | Deposit date: | 2009-07-20 | | Release date: | 2010-09-08 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain.
Nat.Struct.Mol.Biol., 17, 2010
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2CLB
 | | The structure of the DPS-like protein from Sulfolobus solfataricus reveals a bacterioferritin-like di-metal binding site within a Dps- like dodecameric assembly | | Descriptor: | DPS-LIKE PROTEIN, FE (III) ION, ZINC ION | | Authors: | Gauss, G.H, Benas, P, Wiedenheft, B, Young, M, Douglas, T, Lawrence, C.M. | | Deposit date: | 2006-04-26 | | Release date: | 2006-07-17 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of the Dps-Like Protein from Sulfolobus Solfataricus Reveals a Bacterioferritin-Like Dimetal Binding Site within a Dps-Like Dodecameric Assembly.
Biochemistry, 45, 2006
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1EZR
 | | CRYSTAL STRUCTURE OF NUCLEOSIDE HYDROLASE FROM LEISHMANIA MAJOR | | Descriptor: | CALCIUM ION, NUCLEOSIDE HYDROLASE | | Authors: | Shi, W, Schramm, V.L, Almo, S.C. | | Deposit date: | 2000-05-11 | | Release date: | 2000-05-24 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Nucleoside hydrolase from Leishmania major. Cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-a crystal structure.
J.Biol.Chem., 274, 1999
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2KKJ
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1IMJ
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2KFT
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2H0A
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