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3GUN	T4 lysozyme M102E/L99A mutant with buried charge in apolar cavity--aniline binding Descriptor: ANILINE, CALCIUM ION, CHLORIDE ION, ... Authors: Liu, L, Matthews, B.W. Deposit date: 2009-03-30 Release date: 2009-08-25 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Use of stabilizing mutations to engineer a charged group within a ligand-binding hydrophobic cavity in T4 lysozyme. Biochemistry, 48, 2009
3GUM	T4 lysozyme M102E/L99A mutant with buried charge in apolar cavity--p-xylene binding Descriptor: ACETATE ION, CALCIUM ION, CHLORIDE ION, ... Authors: Liu, L, Matthews, B.W. Deposit date: 2009-03-30 Release date: 2009-08-25 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.24 Å) Cite: Use of stabilizing mutations to engineer a charged group within a ligand-binding hydrophobic cavity in T4 lysozyme. Biochemistry, 48, 2009
3GUJ	T4 lysozyme M102E/L99A mutant with buried charge in apolar cavity--Benzene binding Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BENZENE, BETA-MERCAPTOETHANOL, ... Authors: Liu, L, Matthews, B.W. Deposit date: 2009-03-30 Release date: 2009-08-25 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Use of stabilizing mutations to engineer a charged group within a ligand-binding hydrophobic cavity in T4 lysozyme. Biochemistry, 48, 2009
3GUO	T4 lysozyme M102E/L99A mutant with buried charge in apolar cavity--phenol binding Descriptor: CALCIUM ION, CHLORIDE ION, Lysozyme, ... Authors: Liu, L, Matthews, B.W. Deposit date: 2009-03-30 Release date: 2009-08-25 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.16 Å) Cite: Use of stabilizing mutations to engineer a charged group within a ligand-binding hydrophobic cavity in T4 lysozyme. Biochemistry, 48, 2009
3HDF	Crystal structure of truncated endolysin R21 from phage 21 Descriptor: GLYCEROL, Lysozyme, NITRATE ION Authors: Sun, Q, Sacchettini, J.C. Deposit date: 2009-05-07 Release date: 2009-11-03 Last modified: 2017-11-01 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Regulation of a muralytic enzyme by dynamic membrane topology. Nat.Struct.Mol.Biol., 16, 2009
3HH3	New azaborine compounds bind to the T4 lysozyme L99A cavity - 1,2-dihydro-1,2-azaborine Descriptor: 1,2-dihydro-1,2-azaborinine, 2-HYDROXYETHYL DISULFIDE, Lysozyme, ... Authors: Liu, L, Matthews, B.W. Deposit date: 2009-05-14 Release date: 2009-10-13 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Boron mimetics: 1,2-dihydro-1,2-azaborines bind inside a nonpolar cavity of T4 lysozyme. Angew.Chem.Int.Ed.Engl., 48, 2009
3HH4	New azaborine compounds bind to the T4 lysozyme L99A cavity - Benzene as control Descriptor: 2-HYDROXYETHYL DISULFIDE, BENZENE, Lysozyme, ... Authors: Liu, L, Matthews, B.W. Deposit date: 2009-05-14 Release date: 2009-10-13 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Boron mimetics: 1,2-dihydro-1,2-azaborines bind inside a nonpolar cavity of T4 lysozyme. Angew.Chem.Int.Ed.Engl., 48, 2009
3HH5	New azaborine compounds bind to the T4 lysozyme L99A cavity - 1-ethyl-2-hydro-1,2-azaborine Descriptor: 1-ethyl-1,2-dihydro-1,2-azaborinine, 2-HYDROXYETHYL DISULFIDE, Lysozyme, ... Authors: Liu, L, Matthews, B.W. Deposit date: 2009-05-14 Release date: 2009-10-13 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Boron mimetics: 1,2-dihydro-1,2-azaborines bind inside a nonpolar cavity of T4 lysozyme. Angew.Chem.Int.Ed.Engl., 48, 2009
3HH6	New azaborine compounds bind to the T4 lysozyme L99A cavity -ethylbenzene as control Descriptor: 2-HYDROXYETHYL DISULFIDE, Lysozyme, PHENYLETHANE, ... Authors: Liu, L, Matthews, B.W. Deposit date: 2009-05-14 Release date: 2009-10-13 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Boron mimetics: 1,2-dihydro-1,2-azaborines bind inside a nonpolar cavity of T4 lysozyme. Angew.Chem.Int.Ed.Engl., 48, 2009
3HDE	Crystal structure of full-length endolysin R21 from phage 21 Descriptor: Lysozyme Authors: Sun, Q, Arockiasamy, A, McKee, E, Caronna, E, Sacchettini, J.C. Deposit date: 2009-05-07 Release date: 2009-11-03 Last modified: 2017-11-01 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Regulation of a muralytic enzyme by dynamic membrane topology. Nat.Struct.Mol.Biol., 16, 2009
3FI5	Crystal Structure of T4 Lysozyme Mutant R96W Descriptor: CHLORIDE ION, ISOPROPYL ALCOHOL, Lysozyme, ... Authors: Mooers, B.H.M, Matthews, B.W. Deposit date: 2008-12-11 Release date: 2009-02-17 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.53 Å) Cite: Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme. Protein Sci., 18, 2009
3JR6	Sequential reorganization of beta-sheet topology by insertion of a single strand Descriptor: Lysozyme, SULFATE ION Authors: Sagermann, M, Baas, W.A, Matthews, B.W. Deposit date: 2009-09-08 Release date: 2009-10-20 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (3 Å) Cite: Sequential reorganization of beta-sheet topology by insertion of a single strand. Protein Sci., 15, 2006
220L	GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS Descriptor: BENZENE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... Authors: Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W. Deposit date: 1997-06-25 Release date: 1998-03-18 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions. J.Mol.Biol., 277, 1998
225L	GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS Descriptor: BETA-MERCAPTOETHANOL, PARA-XYLENE, T4 LYSOZYME Authors: Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W. Deposit date: 1997-06-25 Release date: 1998-03-18 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions. J.Mol.Biol., 277, 1998
232L	T4 LYSOZYME MUTANT M120K Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Lipscomb, L.A, Drew, D.L, Gassner, N, Baase, W.A, Matthews, B.W. Deposit date: 1997-10-05 Release date: 1998-01-14 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Context-dependent protein stabilization by methionine-to-leucine substitution shown in T4 lysozyme. Protein Sci., 7, 1998
221L	THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Blaber, M, Matthews, B.W. Deposit date: 1993-05-28 Release date: 1994-01-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme. Biochemistry, 32, 1993
233L	T4 LYSOZYME MUTANT M120L Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Lipscomb, L.A, Drew, D.L, Gassner, N, Baase, W.A, Matthews, B.W. Deposit date: 1997-10-07 Release date: 1998-01-14 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Context-dependent protein stabilization by methionine-to-leucine substitution shown in T4 lysozyme. Protein Sci., 7, 1998
200L	THERMODYNAMIC AND STRUCTURAL COMPENSATION IN "SIZE-SWITCH" CORE-REPACKING VARIANTS OF T4 LYSOZYME Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME Authors: Baldwin, E, Xu, J, Hajiseyedjavadi, O, Matthews, B.W. Deposit date: 1995-11-06 Release date: 1996-03-08 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Thermodynamic and structural compensation in "size-switch" core repacking variants of bacteriophage T4 lysozyme. J.Mol.Biol., 259, 1996
205L	HOW AMINO-ACID INSERTIONS ARE ALLOWED IN AN ALPHA-HELIX OF T4 LYSOZYME Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Heinz, D.W, Matthews, B.W. Deposit date: 1993-10-12 Release date: 1994-01-31 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.1 Å) Cite: How amino-acid insertions are allowed in an alpha-helix of T4 lysozyme. Nature, 361, 1993
1ZUR	Crystal structure of spin labeled T4 Lysozyme (V131R1F) Descriptor: CHLORIDE ION, Lysozyme, S-[(1-oxyl-2,2,5,5-tetramethyl-4-phenyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate Authors: Fleissner, M.R, Cascio, D, Sawaya, M.R, Hideg, K, Hubbell, W.L. Deposit date: 2005-05-31 Release date: 2006-10-17 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystal structure of spin labeled T4 Lysozyme (V131R1F) To be Published
228L	GENERATING LIGAND BINDING SITES IN T4 LYSOZYME USING DEFICIENCY-CREATING SUBSTITUTIONS Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME Authors: Baldwin, E.P, Baase, W.A, Zhang, X.-J, Feher, V, Matthews, B.W. Deposit date: 1997-06-25 Release date: 1998-03-18 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions. J.Mol.Biol., 277, 1998
235L	THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, T4 LYSOZYME Authors: Xu, J, Baase, W.A, Baldwin, E, Matthews, B.W. Deposit date: 1997-10-17 Release date: 1998-03-18 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The response of T4 lysozyme to large-to-small substitutions within the core and its relation to the hydrophobic effect. Protein Sci., 7, 1998
242L	THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, T4 LYSOZYME Authors: Xu, J, Baase, W.A, Baldwin, E, Matthews, B.W. Deposit date: 1997-10-23 Release date: 1998-03-18 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The response of T4 lysozyme to large-to-small substitutions within the core and its relation to the hydrophobic effect. Protein Sci., 7, 1998
231L	T4 LYSOZYME MUTANT M106K Descriptor: CHLORIDE ION, T4 LYSOZYME Authors: Lipscomb, L.A, Drew, D.L, Gassner, N, Baase, W.A, Matthews, B.W. Deposit date: 1997-10-03 Release date: 1998-01-14 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Context-dependent protein stabilization by methionine-to-leucine substitution shown in T4 lysozyme. Protein Sci., 7, 1998
238L	THE RESPONSE OF T4 LYSOZYME TO LARGE-TO-SMALL SUBSTITUTIONS WITHIN THE CORE AND ITS RELATION TO THE HYDROPHOBIC EFFECT Descriptor: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, T4 LYSOZYME Authors: Xu, J, Baase, W.A, Baldwin, E, Matthews, B.W. Deposit date: 1997-10-23 Release date: 1998-03-18 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.8 Å) Cite: The response of T4 lysozyme to large-to-small substitutions within the core and its relation to the hydrophobic effect. Protein Sci., 7, 1998

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