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7RBN
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BU of 7rbn by Molmil
Human DNA polymerase beta crosslinked complex, 20 min Ca to Mg exchange
Descriptor: 2-deoxy-3,5-di-O-phosphono-D-erythro-pentitol, DNA (5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ...
Authors:Kumar, A.
Deposit date:2021-07-06
Release date:2022-03-09
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Interlocking activities of DNA polymerase beta in the base excision repair pathway.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RBH
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BU of 7rbh by Molmil
Human DNA polymerase beta crosslinked ternary complex 2
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 2-deoxy-3,5-di-O-phosphono-D-erythro-pentitol, CALCIUM ION, ...
Authors:Kumar, A.
Deposit date:2021-07-06
Release date:2022-03-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Interlocking activities of DNA polymerase beta in the base excision repair pathway.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RBL
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BU of 7rbl by Molmil
Human DNA polymerase beta crosslinked complex, 60 s Ca to Mg exchange
Descriptor: 2-deoxy-3,5-di-O-phosphono-D-erythro-pentitol, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3'), DNA (5'-D(*GP*TP*CP*GP*G)-3'), ...
Authors:Kumar, A.
Deposit date:2021-07-06
Release date:2022-03-09
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Interlocking activities of DNA polymerase beta in the base excision repair pathway.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RBF
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BU of 7rbf by Molmil
Human DNA polymerase beta crosslinked binary complex - B
Descriptor: 1,2-ETHANEDIOL, 2-deoxy-3,5-di-O-phosphono-D-erythro-pentitol, DI(HYDROXYETHYL)ETHER, ...
Authors:Reed, A.J, Kumar, A.
Deposit date:2021-07-06
Release date:2022-03-09
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Interlocking activities of DNA polymerase beta in the base excision repair pathway.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RBJ
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BU of 7rbj by Molmil
Human DNA polymerase beta crosslinked complex, 30 s Ca to Mg exchange
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 2-deoxy-3,5-di-O-phosphono-D-erythro-pentitol, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3'), ...
Authors:Kumar, A.
Deposit date:2021-07-06
Release date:2022-03-09
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Interlocking activities of DNA polymerase beta in the base excision repair pathway.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RBM
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BU of 7rbm by Molmil
Human DNA polymerase beta crosslinked complex, 60 s Ca to Mn exchange
Descriptor: 2-deoxy-3,5-di-O-phosphono-D-erythro-pentitol, DNA (5'-D(*CP*CP*GP*AP*CP*GP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3'), ...
Authors:Kumar, A.
Deposit date:2021-07-06
Release date:2022-03-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Interlocking activities of DNA polymerase beta in the base excision repair pathway.
Proc.Natl.Acad.Sci.USA, 119, 2022
4ZTZ
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BU of 4ztz by Molmil
Structural basis for processivity and antiviral drug toxicity in human mitochondrial DNA replicase
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*AP*AP*GP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), ...
Authors:Szymanski, M.R, Yin, Y.W.
Deposit date:2015-05-15
Release date:2015-09-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.442 Å)
Cite:Structural basis for processivity and antiviral drug toxicity in human mitochondrial DNA replicase
EMBO J., 34, 2015
5D5X
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BU of 5d5x by Molmil
Crystal structure of Chaetomium thermophilum Skn7 with SSRE DNA
Descriptor: Putative transcription factor, SSRE DNA strand 1, SSRE DNA strand 2
Authors:Neudegger, T, Verghese, J, Hayer-Hartl, M, Hartl, F.U, Bracher, A.
Deposit date:2015-08-11
Release date:2015-12-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of human heat-shock transcription factor 1 in complex with DNA.
Nat.Struct.Mol.Biol., 23, 2016
4IHS
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BU of 4ihs by Molmil
Crystal Structure of BenM_DBD/catB site 1 DNA Complex
Descriptor: HTH-type transcriptional regulator BenM, MALONATE ION, SODIUM ION, ...
Authors:Alanazi, A, Momany, C, Neidle, E.L.
Deposit date:2012-12-19
Release date:2013-07-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The DNA-binding domain of BenM reveals the structural basis for the recognition of a T-N11-A sequence motif by LysR-type transcriptional regulators.
Acta Crystallogr.,Sect.D, 69, 2013
8D37
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BU of 8d37 by Molmil
Human mitochondrial DNA polymerase gamma ternary complex with GT basepair in replication conformer
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (25-MER), ...
Authors:Park, J, Yin, Y.W.
Deposit date:2022-05-31
Release date:2023-05-24
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Pol gamma coordinates DNA synthesis and proofreading to ensure mitochondrial genome integrity.
Nat.Struct.Mol.Biol., 30, 2023
8D33
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BU of 8d33 by Molmil
Human mitochondrial DNA polymerase gamma ternary complex with GC basepair
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (25-MER), ...
Authors:Park, J, Yin, Y.W.
Deposit date:2022-05-31
Release date:2023-05-24
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.46 Å)
Cite:Pol gamma coordinates DNA synthesis and proofreading to ensure mitochondrial genome integrity.
Nat.Struct.Mol.Biol., 30, 2023
8D3R
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BU of 8d3r by Molmil
Human mitochondrial DNA polymerase gamma ternary complex with GT basepair in intermediate conformer
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*TP*AP*T)-3'), ...
Authors:Park, J, Yin, Y.W.
Deposit date:2022-06-01
Release date:2023-05-24
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Pol gamma coordinates DNA synthesis and proofreading to ensure mitochondrial genome integrity.
Nat.Struct.Mol.Biol., 30, 2023
8D42
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BU of 8d42 by Molmil
Human mitochondrial DNA polymerase gamma ternary complex with GT basepair in editing conformer (composite)
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*TP*AP*T)-3'), ...
Authors:Park, J, Yin, Y.W.
Deposit date:2022-06-01
Release date:2023-05-24
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.91 Å)
Cite:Pol gamma coordinates DNA synthesis and proofreading to ensure mitochondrial genome integrity.
Nat.Struct.Mol.Biol., 30, 2023
4IHT
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BU of 4iht by Molmil
Crystal Structure of BenM_DBD/benA site 1 DNA Complex
Descriptor: HTH-type transcriptional regulator BenM, benA site 1 DNA, benA site 1 DNA - complement
Authors:Alanazi, A, Momany, C, Neidle, E.L.
Deposit date:2012-12-19
Release date:2013-07-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:The DNA-binding domain of BenM reveals the structural basis for the recognition of a T-N11-A sequence motif by LysR-type transcriptional regulators.
Acta Crystallogr.,Sect.D, 69, 2013
8F6B
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BU of 8f6b by Molmil
Crystal structure of murine PolG2 hexamer bound to DNA
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, DNA (5'-D(*CP*TP*GP*GP*TP*AP*GP*GP*CP*GP*CP*CP*TP*AP*CP*CP*AP*G)-3'), ...
Authors:Wojtaszek, J.L, Hoff, K.E, Williams, R.S.
Deposit date:2022-11-16
Release date:2023-08-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure-specific roles for PolG2-DNA complexes in maintenance and replication of mitochondrial DNA.
Nucleic Acids Res., 51, 2023
8F69
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BU of 8f69 by Molmil
Crystal structure of murine PolG2 dimer bound to DNA
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Wojtaszek, J.L, Hoff, K.E, Williams, R.S.
Deposit date:2022-11-16
Release date:2023-08-09
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-specific roles for PolG2-DNA complexes in maintenance and replication of mitochondrial DNA.
Nucleic Acids Res., 51, 2023
5D5W
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BU of 5d5w by Molmil
Crystal structure of Chaetomium thermophilum Skn7 with HSE DNA
Descriptor: HSE DNA, Putative transcription factor
Authors:Neudegger, T, Verghese, J, Hayer-Hartl, M, Hartl, F.U, Bracher, A.
Deposit date:2015-08-11
Release date:2015-12-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure of human heat-shock transcription factor 1 in complex with DNA.
Nat.Struct.Mol.Biol., 23, 2016
4WUZ
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BU of 4wuz by Molmil
Crystal structure of lambda exonuclease in complex with DNA and Ca2+
Descriptor: CALCIUM ION, DNA (5'-D(*TP*T*TP*CP*GP*GP*TP*AP*CP*AP*GP*TP*AP*G)-3'), DNA (5'-D(P*AP*GP*CP*TP*AP*CP*TP*GP*TP*AP*CP*CP*GP*A)-3'), ...
Authors:Zhang, J, Bell, C.E.
Deposit date:2014-11-04
Release date:2014-11-19
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal Structure of lambda Exonuclease in Complex with DNA and Ca(2+).
Biochemistry, 53, 2014
2XRO
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BU of 2xro by Molmil
Crystal structure of TtgV in complex with its DNA operator
Descriptor: HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGV, OSMIUM ION, TTGV OPERATOR DNA
Authors:Lu, D, Fillet, S, Meng, C, Alguel, Y, Kloppsteck, P, Bergeron, J, Krell, T, Gallegos, M.-T, Ramos, J, Zhang, X.
Deposit date:2010-09-17
Release date:2010-12-01
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal Structure of Ttgv in Complex with its DNA Operator Reveals a General Model for Cooperative DNA Binding of Tetrameric Gene Regulators.
Genes Dev., 24, 2010
1HLZ
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BU of 1hlz by Molmil
CRYSTAL STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB(ALPHA) DNA-BINDING DOMAIN BOUND TO ITS COGNATE RESPONSE ELEMENT
Descriptor: 5'-D(*CP*AP*AP*CP*TP*AP*GP*GP*TP*CP*AP*CP*TP*AP*GP*GP*TP*CP*AP*G)-3', 5'-D(*CP*TP*GP*AP*CP*CP*TP*AP*GP*TP*GP*AP*CP*CP*TP*AP*GP*TP*TP*G)-3', ORPHAN NUCLEAR RECEPTOR NR1D1, ...
Authors:Sierk, M.L, Zhao, Q, Rastinejad, F.
Deposit date:2000-12-04
Release date:2001-11-16
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:DNA Deformability as a Recognition Feature in the RevErb Response Element
Biochemistry, 40, 2001
8G9O
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BU of 8g9o by Molmil
Complete DNA elongation subcomplex of Xenopus laevis DNA polymerase alpha-primase
Descriptor: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ...
Authors:Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F.
Deposit date:2023-02-21
Release date:2023-04-12
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
6KRH
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BU of 6krh by Molmil
Structural basis for domain rotation during adenylation of active site K123 and fragment library screening against NAD+ -dependent DNA ligase from Mycobacterium tuberculosis
Descriptor: ADENOSINE MONOPHOSPHATE, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, DNA ligase A, ...
Authors:Ramachandran, R, Shukla, A, Afsar, M.
Deposit date:2019-08-21
Release date:2020-08-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Salt bridges at the subdomain interfaces of the adenylation domain and active-site residues of Mycobacterium tuberculosis NAD + -dependent DNA ligase A (MtbLigA) are important for the initial steps of nick-sealing activity.
Acta Crystallogr D Struct Biol, 77, 2021
7K04
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BU of 7k04 by Molmil
Structure of TFIIH/Rad4-Rad23-Rad33/DNA in DNA opening
Descriptor: CALCIUM ION, DNA repair helicase RAD25, DNA repair helicase RAD3, ...
Authors:van Eeuwen, T, Min, J.H, Murakami, K.
Deposit date:2020-09-03
Release date:2021-07-28
Method:ELECTRON MICROSCOPY (9.25 Å)
Cite:Cryo-EM structure of TFIIH/Rad4-Rad23-Rad33 in damaged DNA opening in nucleotide excision repair.
Nat Commun, 12, 2021
4TUS
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BU of 4tus by Molmil
Human DNA polymerase beta inserting dCMPNPP opposite the 5'G of cisplatin crosslinked Gs (Pt-GG2) WITH MANGANESE IN THE ACTIVE SITE.
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, Cisplatin, DNA (5'-D(*CP*CP*CP*AP*CP*GP*GP*CP*CP*CP*AP*TP*CP*AP*CP*C)-3'), ...
Authors:Koag, M.C, Lee, S.
Deposit date:2014-06-24
Release date:2014-10-01
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural Basis for the Inefficient Nucleotide Incorporation Opposite Cisplatin-DNA Lesion by Human DNA Polymerase beta.
J.Biol.Chem., 289, 2014
1L9Z
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BU of 1l9z by Molmil
Thermus aquaticus RNA Polymerase Holoenzyme/Fork-Junction Promoter DNA Complex at 6.5 A Resolution
Descriptor: MAGNESIUM ION, RNA POLYMERASE, ALPHA SUBUNIT, ...
Authors:Murakami, K.S, Masuda, S, Campbell, E.A, Muzzin, O, Darst, S.A.
Deposit date:2002-03-27
Release date:2002-05-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (6.5 Å)
Cite:Structural basis of transcription initiation: an RNA polymerase holoenzyme-DNA complex.
Science, 296, 2002

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數據於2024-11-06公開中

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