8XSR
 
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8XST
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2CIG
 | | Dihydrofolate reductase from Mycobacterium tuberculosis inhibited by the acyclic 4R isomer of INH-NADP a derivative of the prodrug isoniazid. | | Descriptor: | (4R)-ISONICOTINIC-ACETYL-NICOTINAMIDE-ADENINE DINUCLEOTIDE, DIHYDROFOLATE REDUCTASE, GLYCEROL, ... | | Authors: | Argyrou, A, Vetting, M.W, Aladegbami, B, Blanchard, J.S. | | Deposit date: | 2006-03-20 | | Release date: | 2006-04-25 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Mycobacterium Tuberculosis Dihydrofolate Reductase is a Target for Isoniazid
Nat.Struct.Mol.Biol., 13, 2006
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1Z9W
 | | Tetrameric structure of apo-7,8-Dihydroneopterin Aldolase from Mycobacterium tuberculosis | | Descriptor: | Dihydroneopterin aldolase | | Authors: | Goulding, C.W, Apostol, M.I, Sawaya, M.R, Philips, M, Parseghian, A, Eisenberg, D, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) | | Deposit date: | 2005-04-05 | | Release date: | 2005-04-19 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme.
J.Mol.Biol., 349, 2005
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8WOL
 | | Cryo-EM structure of the Mmp1 encapasulin from Mycobacterium smegmatis | | Descriptor: | Major membrane protein 1 | | Authors: | Zhang, M, Tang, Y, Gao, Y, Liu, X, Lan, W, Liu, Y, Ma, M. | | Deposit date: | 2023-10-07 | | Release date: | 2024-11-27 | | Last modified: | 2025-01-01 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | The structural and functional analysis of mycobacteria cysteine desulfurase-loaded encapsulin.
Commun Biol, 7, 2024
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8WON
 | | Cryo-EM structure of the 10-subunits Mmp1 complex from Mycobacterium smegmatis | | Descriptor: | Major membrane protein I | | Authors: | Zhang, M, Tang, Y, Gao, Y, Liu, X, Lan, W, Liu, Y, Ma, M. | | Deposit date: | 2023-10-07 | | Release date: | 2025-01-01 | | Last modified: | 2025-06-18 | | Method: | ELECTRON MICROSCOPY (2.69 Å) | | Cite: | The structural and functional analysis of mycobacteria cysteine desulfurase-loaded encapsulin.
Commun Biol, 7, 2024
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4KB5
 | | Crystal structure of MycP1 from Mycobacterium smegmatis | | Descriptor: | GLYCEROL, Membrane-anchored mycosin mycp1 | | Authors: | Sun, D.M, He, Y, Tian, C.L. | | Deposit date: | 2013-04-23 | | Release date: | 2014-02-05 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | The putative propeptide of MycP1 in mycobacterial type VII secretion system does not inhibit protease activity but improves protein stability.
Protein Cell, 4, 2013
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7E51
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7E4X
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7ENS
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1P3H
 | | Crystal Structure of the Mycobacterium tuberculosis chaperonin 10 tetradecamer | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 10 kDa chaperonin, CALCIUM ION | | Authors: | Roberts, M.M, Coker, A.R, Fossati, G, Mascagni, P, Coates, A.R.M, Wood, S.P, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2003-04-17 | | Release date: | 2003-07-15 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Mycobacterium tuberculosis chaperonin 10 heptamers self-associate through their biologically active loops
J.BACTERIOL., 185, 2003
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3RYO
 | | Crystal Structure of Enhanced Intracellular Survival (Eis) Protein from Mycobacterium tuberculosis with Acetyl CoA | | Descriptor: | ACETYL COENZYME *A, Enhanced intracellular survival protein | | Authors: | Kim, K.H, An, D.R, Yoon, J.Y, Kim, H.S, Yoon, H.J, Song, J, Im, H.N, Kim, J, Kim, D.J, Lee, S.J, Kim, H.J, Lee, J.Y, Suh, S.W. | | Deposit date: | 2011-05-11 | | Release date: | 2012-05-23 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Mycobacterium tuberculosis Eis protein initiates suppression of host immune responses by acetylation of DUSP16/MKP-7
Proc.Natl.Acad.Sci.USA, 2012
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4HVL
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2FYF
 | | Structure of a putative phosphoserine aminotransferase from Mycobacterium Tuberculosis | | Descriptor: | GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION, ... | | Authors: | Coulibaly, F, Lassalle, E, Baker, E.N, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) | | Deposit date: | 2006-02-07 | | Release date: | 2007-01-16 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structure of phosphoserine aminotransferase from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 68, 2012
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6YRK
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2E3J
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2I3A
 | | Crystal structure of N-Acetyl-gamma-Glutamyl-Phosphate Reductase (Rv1652) from Mycobacterium tuberculosis | | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N-acetyl-gamma-glutamyl-phosphate reductase | | Authors: | Cherney, L.T, Cherney, M.M, Garen, C.R, Moraidin, F, James, M.N.G, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) | | Deposit date: | 2006-08-17 | | Release date: | 2006-08-29 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Crystal Structure of N-acetyl-gamma-glutamyl-phosphate Reductase from Mycobacterium tuberculosis in Complex with NADP(+).
J.Mol.Biol., 367, 2007
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4J94
 | | Crystal structure of MycP1 from the ESX-1 type VII secretion system | | Descriptor: | Membrane-anchored mycosin mycp1 | | Authors: | Solomonson, M, Wasney, G.A, Watanabe, N, Gruninger, R.J, Prehna, G, Strynadka, N.C.J. | | Deposit date: | 2013-02-15 | | Release date: | 2013-05-01 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.857 Å) | | Cite: | Structure of the Mycosin-1 Protease from the Mycobacterial ESX-1 Protein Type VII Secretion System.
J.Biol.Chem., 288, 2013
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4M1Z
 | | Crystal structure of MycP1 with the N-terminal propeptide removed | | Descriptor: | Membrane-anchored mycosin mycp1 | | Authors: | Sun, D.M, He, Y, Wang, C.L, Zang, J.Y, Tian, C.L. | | Deposit date: | 2013-08-04 | | Release date: | 2014-02-12 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | The putative propeptide of MycP1 in mycobacterial type VII secretion system does not inhibit protease activity but improves protein stability.
Protein Cell, 4, 2013
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4KPG
 | | Crystal structure of MycP1 from the ESX-1 type VII secretion system | | Descriptor: | Membrane-anchored mycosin mycp1 | | Authors: | Solomonson, M, Wasney, G.A, Watanabe, N, Gruninger, R.J, Prehna, G, Strynadka, N.C.J. | | Deposit date: | 2013-05-13 | | Release date: | 2013-05-22 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.148 Å) | | Cite: | Structure of the Mycosin-1 Protease from the Mycobacterial ESX-1 Protein Type VII Secretion System.
J.Biol.Chem., 288, 2013
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7CL3
 | | The crystal structure of KanJ in complex with kanamycin B | | Descriptor: | (1R,2S,3S,4R,6S)-4,6-DIAMINO-3-[(3-AMINO-3-DEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-2-HYDROXYCYCLOHEXYL 2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSIDE, Kanamycin B dioxygenase, NICKEL (II) ION, ... | | Authors: | Kitayama, Y, Miyanaga, A, Kudo, F, Eguchi, T. | | Deposit date: | 2020-07-20 | | Release date: | 2021-01-13 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Stepwise Post-glycosylation Modification of Sugar Moieties in Kanamycin Biosynthesis.
Chembiochem, 22, 2021
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3SXN
 | | Mycobacterium tuberculosis Eis protein initiates modulation of host immune responses by acetylation of DUSP16/MKP-7 | | Descriptor: | COENZYME A, Enhanced intracellular survival protein | | Authors: | Kim, K.H, An, D.R, Yoon, J.Y, Kim, H.S, Yoon, H.J, Song, J.S, Im, H.N, Kim, J, Kim, D.J, Lee, S.J, Kim, H.J, Lee, J.Y, Suh, S.W. | | Deposit date: | 2011-07-15 | | Release date: | 2012-05-23 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Mycobacterium tuberculosis Eis protein initiates suppression of host immune responses by acetylation of DUSP16/MKP-7
Proc.Natl.Acad.Sci.USA, 109, 2012
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4N8N
 | | Crystal structure of Mycobacterial FtsX extracellular domain | | Descriptor: | Cell division protein FtsX, POTASSIUM ION | | Authors: | Mavrici, D. | | Deposit date: | 2013-10-17 | | Release date: | 2014-05-28 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.874 Å) | | Cite: | Mycobacterium tuberculosis FtsX extracellular domain activates the peptidoglycan hydrolase, RipC.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4NL5
 | | Mycobacterium tuberculosis heme-degrading protein MhuD in complex with heme and cyanide | | Descriptor: | ACETATE ION, CYANIDE ION, Heme-degrading monooxygenase HmoB, ... | | Authors: | Morse, R.P, Chao, A, Goulding, C.W. | | Deposit date: | 2013-11-13 | | Release date: | 2014-06-25 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystallographic and Spectroscopic Insights into Heme Degradation by Mycobacterium tuberculosis MhuD.
Inorg.Chem., 53, 2014
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7B9F
 | | Structure of the mycobacterial ESX-5 Type VII Secretion System hexameric pore complex | | Descriptor: | EccB5, EccC5, EccD5, ... | | Authors: | Chojnowski, G, Ritter, C, Beckham, K.S.H, Mullapudi, E, Rettel, M, Savitski, M.M, Mortensen, S.A, Ziemianowicz, D, Kosinski, J, Wilmanns, M. | | Deposit date: | 2020-12-14 | | Release date: | 2021-07-07 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structure of the mycobacterial ESX-5 type VII secretion system pore complex.
Sci Adv, 7, 2021
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