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7N9I
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BU of 7n9i by Molmil
1.4A Structure of Drosophila melanogaster Frataxin
Descriptor: Frataxin homolog, mitochondrial, SULFATE ION
Authors:Brunzelle, J.S, Stemmler, T.L.
Deposit date:2021-06-17
Release date:2022-06-22
Last modified:2024-08-07
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Drosophila melanogaster frataxin: protein crystal and predicted solution structure with identification of the iron-binding regions.
Acta Crystallogr D Struct Biol, 79, 2023
7N69
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Pre-fusion state 2 of EEEV with localized reconstruction
Descriptor: Spike glycoprotein E1, Spike glycoprotein E2
Authors:Chen, C.-L, Kuhn, R.J, Klose, T.
Deposit date:2021-06-07
Release date:2022-06-22
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (14.1 Å)
Cite:Cryo-EM structures of alphavirus conformational intermediates in low pH-triggered prefusion states.
Proc.Natl.Acad.Sci.USA, 119, 2022
7MYJ
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BU of 7myj by Molmil
Structure of full length human AMPK (a2b1g1) in complex with a small molecule activator MSG011
Descriptor: (5S,6R,7R,9R,13cR,14R,16aS)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,14,15,16,16a-octahydro-5H,13cH-5,9-epoxy-4b,9a,1 5-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-ol, 5'-AMP-activated protein kinase catalytic subunit alpha-2, 5'-AMP-activated protein kinase subunit beta-1, ...
Authors:Ovens, A.J, Gee, Y.S, Ling, N.X.Y, Waters, N.J, Yu, D, Scott, J.W, Parker, M.W, Hoffman, N.J, Kemp, B.E, Baell, J.B, Oakhill, J.S, Langendorf, C.G.
Deposit date:2021-05-21
Release date:2022-06-29
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structure-function analysis of the AMPK activator SC4 and identification of a potent pan AMPK activator.
Biochem.J., 479, 2022
7N9U
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BU of 7n9u by Molmil
CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions
Descriptor: Capsid protein, Nanobody
Authors:Gerber, E.E, Digianantonio, K.M, Tripler, T.N, Smaga, S.S, Summers, B.J, Xiong, Y.
Deposit date:2021-06-18
Release date:2022-06-22
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions
To Be Published
3D4K
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BU of 3d4k by Molmil
Concanavalin A Complexed to a Synthetic Analog of the Trimannoside
Descriptor: CALCIUM ION, Concanavalin-A, GLYCEROL, ...
Authors:Kadirvelraj, R, Foley, B.L, Dyekjaer, J.D, Woods, R.J.
Deposit date:2008-05-14
Release date:2009-03-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Involvement of water in carbohydrate-protein binding: concanavalin A revisited.
J.Am.Chem.Soc., 130, 2008
7N9X
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BU of 7n9x by Molmil
CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions
Descriptor: Capsid protein, Nanobody, Peptidyl-prolyl cis-trans isomerase A
Authors:Gerber, E.E, Digianantonio, K.M, Tripler, T.N, Smaga, S.S, Summers, B.J, Xiong, Y.
Deposit date:2021-06-18
Release date:2022-06-22
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.511 Å)
Cite:CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions
To Be Published
3CUJ
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BU of 3cuj by Molmil
Cellulomonas fimi Xylanase/Cellulase Cex (Cf Xyn10A) in complex with sulfur substituted beta-1,4 xylopentaose.
Descriptor: Exo-beta-1,4-glucanase, beta-D-xylopyranose-(1-4)-4-thio-beta-D-xylopyranose-(1-4)-4-thio-beta-D-xylopyranose-(1-4)-4-thio-beta-D-xylopyranose-(1-4)-4-thio-beta-D-xylopyranose
Authors:Kuntz, D.A, Saul, M, Rose, D.R.
Deposit date:2008-04-16
Release date:2009-04-21
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Probing the binding sites of Family 10 and 11 Xylanases with extended Oligosaccharides
to be published
7MU5
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BU of 7mu5 by Molmil
Human DCTPP1 bound to Triptolide
Descriptor: MAGNESIUM ION, dCTP pyrophosphatase 1, triptolide
Authors:Hauk, G, Berger, J.M.
Deposit date:2021-05-14
Release date:2022-08-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Triptolide sensitizes cancer cells to nucleoside DNA methyltransferase inhibitors through inhibition of DCTPP1 mediated cell-intrinsic resistance
To Be Published
7MY6
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BU of 7my6 by Molmil
Se-CrtE C-term His-tag with IPP added
Descriptor: 1,2-ETHANEDIOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, CHLORIDE ION, ...
Authors:Peat, T.S, Newman, J.
Deposit date:2021-05-20
Release date:2022-08-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Molecular characterization of cyanobacterial short-chain prenyltransferases and discovery of a novel GGPP phosphatase.
Febs J., 289, 2022
7MME
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BU of 7mme by Molmil
Crystal structure of HCV NS3/4A D168A protease in complex with JZ01-15
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, NS3/4A protease, ...
Authors:Zephyr, J, Schiffer, C.A.
Deposit date:2021-04-29
Release date:2022-08-31
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Deciphering the Molecular Mechanism and Role of Fluorination in HCV Protease Inhibitor Potency and Drug Resistance
To Be Published
7MMD
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BU of 7mmd by Molmil
Crystal structure of HCV NS3/4A D168A protease in complex with JZ01-19
Descriptor: 1,2-ETHANEDIOL, NS3/4A protease, SULFATE ION, ...
Authors:Zephyr, J, Schiffer, C.A.
Deposit date:2021-04-29
Release date:2022-08-31
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Deciphering the Molecular Mechanism of HCV Protease Inhibitor Fluorination as a General Approach to Avoid Drug Resistance.
J.Mol.Biol., 434, 2022
7MZO
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BU of 7mzo by Molmil
Crystal structure of the UcaD lectin-binding domain
Descriptor: CHLORIDE ION, Fimbrial adhesin UcaD
Authors:Ve, T, Lo, A.W, Schembri, M.A, Kobe, B.
Deposit date:2021-05-24
Release date:2022-07-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Ucl fimbriae regulation and glycan receptor specificity contribute to gut colonisation by extra-intestinal pathogenic Escherichia coli.
Plos Pathog., 18, 2022
7N8W
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BU of 7n8w by Molmil
Crystal structure of ERI2 nuclease bound to rAMP
Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, ERI1 exoribonuclease 2, ...
Authors:Thapar, R, Arvai, A.S, Tainer, J.A.
Deposit date:2021-06-15
Release date:2022-07-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of ERI2 nuclease bound to rAMP
To Be Published
7MZP
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BU of 7mzp by Molmil
Crystal structure of the UclD lectin-binding domain
Descriptor: F17-like fimbril adhesin subunit UclD, IODIDE ION
Authors:Ve, T, Lo, A.W, Schembri, M.A, Kobe, B.
Deposit date:2021-05-24
Release date:2022-07-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Ucl fimbriae regulation and glycan receptor specificity contribute to gut colonisation by extra-intestinal pathogenic Escherichia coli.
Plos Pathog., 18, 2022
7N8V
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BU of 7n8v by Molmil
Crystal structure of free ERI2 nuclease
Descriptor: ERI1 exoribonuclease 2, SULFATE ION
Authors:Thapar, R, Arvai, A.S, Tainer, J.A.
Deposit date:2021-06-15
Release date:2022-07-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of free ERI2 nuclease
To Be Published
7N3Y
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BU of 7n3y by Molmil
Crystal Structure of Saccharomyces cerevisiae Apn2 Catalytic Domain E59Q/D222N Mutant in Complex with DNA
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CITRIC ACID, ...
Authors:Wojtaszek, J.L, Krahn, J, Wallace, B.D, Williams, R.S.
Deposit date:2021-06-02
Release date:2022-09-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Molecular basis for processing of topoisomerase 1-triggered DNA damage by Apn2/APE2.
Cell Rep, 41, 2022
7N3Z
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BU of 7n3z by Molmil
Crystal Structure of Saccharomyces cerevisiae Apn2 Catalytic Domain
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DNA-(apurinic or apyrimidinic site) endonuclease 2, ...
Authors:Wojtaszek, J.L, Wallace, B.D, Williams, R.S.
Deposit date:2021-06-02
Release date:2022-09-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Molecular basis for processing of topoisomerase 1-triggered DNA damage by Apn2/APE2.
Cell Rep, 41, 2022
7N4K
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BU of 7n4k by Molmil
6218 TCR in complex with H2-Db PA 224
Descriptor: Beta-2-microglobulin, Fusion protein of T cell receptor alpha variable 21-DV12 and T-cell receptor, sp3.4 alpha chain, ...
Authors:Szeto, C, Gras, S.
Deposit date:2021-06-04
Release date:2022-07-20
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus.
Nat Commun, 13, 2022
7N5C
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BU of 7n5c by Molmil
6218 TCR in complex with H2Db PA with an engineered TCR-pMHC disulfide bond
Descriptor: Beta-2-microglobulin, Fusion protein of T cell receptor alpha variable 21-DV12 with T-cell receptor, sp3.4 alpha chain, ...
Authors:Szeto, C, Gras, S.
Deposit date:2021-06-05
Release date:2022-07-20
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus.
Nat Commun, 13, 2022
7N5P
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BU of 7n5p by Molmil
6218 TCR in complex with H2-Db PA224-233 with a cysteine mutant
Descriptor: Beta-2-microglobulin, Fusion protein of T cell receptor alpha variable 21-DV12 and T-cell receptor, sp3.4 alpha chain, ...
Authors:Szeto, C, Gras, S.
Deposit date:2021-06-06
Release date:2022-07-20
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus.
Nat Commun, 13, 2022
7N99
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BU of 7n99 by Molmil
SDE2 SAP domain apo structure
Descriptor: Isoform 2 of Replication stress response regulator SDE2
Authors:Paung, Y, Weinheimer, A.S, Rageul, J, Khan, A, Ho, B, Tong, M, Alphonse, S, Seeliger, M.A, Kim, H.
Deposit date:2021-06-17
Release date:2022-10-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Extended DNA-binding interfaces beyond the canonical SAP domain contribute to the function of replication stress regulator SDE2 at DNA replication forks.
J.Biol.Chem., 298, 2022
7NAQ
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BU of 7naq by Molmil
Human PA200-20S proteasome complex
Descriptor: INOSITOL HEXAKISPHOSPHATE, Proteasome activator complex subunit 4, Proteasome subunit alpha type-1, ...
Authors:Zhao, J, Makhija, S, Huang, B, Cheng, Y.
Deposit date:2021-06-22
Release date:2022-11-02
Last modified:2025-05-14
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
7NAP
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BU of 7nap by Molmil
Human PA28-20S-PA28 proteasome complex
Descriptor: Proteasome activator complex subunit 1, Proteasome activator complex subunit 2, Proteasome subunit alpha type-1, ...
Authors:Zhao, J, Makhija, S, Huang, B, Cheng, Y.
Deposit date:2021-06-22
Release date:2022-11-02
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
7NAO
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BU of 7nao by Molmil
Human PA28-20S proteasome complex
Descriptor: Proteasome activator complex subunit 1, Proteasome activator complex subunit 2, Proteasome subunit alpha type-1, ...
Authors:Zhao, J, Makhija, S, Huang, B, Cheng, Y.
Deposit date:2021-06-22
Release date:2022-11-02
Last modified:2025-05-28
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
7MKT
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BU of 7mkt by Molmil
Crystal structure of r(GU)11G-NMM complex
Descriptor: N-METHYLMESOPORPHYRIN, POTASSIUM ION, RNA (5'-R(*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*G)-3')
Authors:Bingman, C.A, Roschdi, S, Nomura, Y, Butcher, S.E.
Deposit date:2021-04-26
Release date:2022-11-02
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:An atypical RNA quadruplex marks RNAs as vectors for gene silencing.
Nat.Struct.Mol.Biol., 29, 2022

238582

數據於2025-07-09公開中

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