1FUP
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![BU of 1fup by Molmil](/molmil-images/mine/1fup) | FUMARASE WITH BOUND PYROMELLITIC ACID | Descriptor: | D-MALATE, FUMARASE C, PYROMELLITIC ACID | Authors: | Weaver, T, Banaszak, L. | Deposit date: | 1996-08-29 | Release date: | 1997-03-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystallographic studies of the catalytic and a second site in fumarase C from Escherichia coli. Biochemistry, 35, 1996
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1GL6
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![BU of 1gl6 by Molmil](/molmil-images/mine/1gl6) | Plasmid coupling protein TrwB in complex with the non-hydrolysable GTP analogue GDPNP | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ATPASE, CHLORIDE ION, ... | Authors: | Gomis-Ruth, F.X, Moncalian, G, De La cruz, F, Coll, M. | Deposit date: | 2001-08-28 | Release date: | 2002-05-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The Bacterial Conjugation Protein Trwb Resembles Ring Helicases and F1-ATPase Nature, 409, 2001
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1FXY
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![BU of 1fxy by Molmil](/molmil-images/mine/1fxy) | COAGULATION FACTOR XA-TRYPSIN CHIMERA INHIBITED WITH D-PHE-PRO-ARG-CHLOROMETHYLKETONE | Descriptor: | COAGULATION FACTOR XA-TRYPSIN CHIMERA, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide | Authors: | Hopfner, K.P, Kopetzki, E, Kresse, G.-B, Huber, R, Bode, W, Engh, R.A. | Deposit date: | 1998-04-22 | Release date: | 1998-06-17 | Last modified: | 2013-02-27 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | New enzyme lineages by subdomain shuffling. Proc.Natl.Acad.Sci.USA, 95, 1998
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1FTY
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![BU of 1fty by Molmil](/molmil-images/mine/1fty) | STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN | Descriptor: | 8,9,10-TRIHYDROXY-7-HYDROXYMETHYL-3-METHYL-6-OXA-1,3-DIAZA-SPIRO[4.5]DECANE-2,4-DIONE, GLYCOGEN PHOSPHORYLASE, PYRIDOXAL-5'-PHOSPHATE | Authors: | Watson, K.A, Tsitsanou, K.E, Gregoriou, M, Zographos, S.E, Skamnaki, V.T, Oikonomakos, N.G, Fleet, G.W, Johnson, L.N. | Deposit date: | 2000-09-13 | Release date: | 2000-10-04 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase. Proteins, 61, 2005
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1FZ4
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1GKZ
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![BU of 1gkz by Molmil](/molmil-images/mine/1gkz) | Branched-chain alpha-ketoacid dehydrogenase kinase (BCK) complxed with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Machius, M, Chuang, J.L, Wynn, R.M, Tomchick, D.R, Chuang, D.T. | Deposit date: | 2001-08-22 | Release date: | 2001-10-11 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of Rat Bckd Kinase: Nucleotide-Induced Domain Communication in a Mitochondrial Protein Kinase. Proc.Natl.Acad.Sci.USA, 98, 2001
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1FZG
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![BU of 1fzg by Molmil](/molmil-images/mine/1fzg) | CRYSTAL STRUCTURE OF FRAGMENT D FROM HUMAN FIBRINOGEN WITH THE PEPTIDE LIGAND GLY-HIS-ARG-PRO-AMIDE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN | Authors: | Everse, S.J, Spraggon, G, Veerapandian, L, Doolittle, R.F. | Deposit date: | 1999-01-01 | Release date: | 1999-06-08 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide. Biochemistry, 38, 1999
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1G4A
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![BU of 1g4a by Molmil](/molmil-images/mine/1g4a) | CRYSTAL STRUCTURES OF THE HSLVU PEPTIDASE-ATPASE COMPLEX REVEAL AN ATP-DEPENDENT PROTEOLYSIS MECHANISM | Descriptor: | 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, ATP-DEPENDENT HSL PROTEASE ATP-BINDING SUBUNIT HSLU, ATP-DEPENDENT PROTEASE HSLV | Authors: | Wang, J, Song, J.J, Franklin, M.C, Kamtekar, S, Im, Y.J, Rho, S.H, Seong, I.S, Lee, C.S, Chung, C.H, Eom, S.H. | Deposit date: | 2000-10-26 | Release date: | 2001-02-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structures of the HslVU peptidase-ATPase complex reveal an ATP-dependent proteolysis mechanism. Structure, 9, 2001
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1G0Z
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1G6S
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![BU of 1g6s by Molmil](/molmil-images/mine/1g6s) | STRUCTURE OF EPSP SYNTHASE LIGANDED WITH SHIKIMATE-3-PHOSPHATE AND GLYPHOSATE | Descriptor: | EPSP SYNTHASE, FORMIC ACID, GLYPHOSATE, ... | Authors: | Schonbrunn, E, Eschenburg, S, Shuttleworth, W, Schloss, J.V, Amrhein, N, Evans, J.N.S, Kabsch, W. | Deposit date: | 2000-11-07 | Release date: | 2001-02-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Interaction of the herbicide glyphosate with its target enzyme 5-enolpyruvylshikimate 3-phosphate synthase in atomic detail. Proc.Natl.Acad.Sci.USA, 98, 2001
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1G9Z
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![BU of 1g9z by Molmil](/molmil-images/mine/1g9z) | LAGLIDADG HOMING ENDONUCLEASE I-CREI / DNA PRODUCT COMPLEX WITH MAGNESIUM | Descriptor: | 5'-D(*CP*GP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*C)-3', 5'-D(*GP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*A)-3', 5'-D(P*GP*AP*CP*AP*GP*TP*TP*TP*CP*G)-3', ... | Authors: | Chevalier, B, Monnat, R.J, Stoddard, B.L. | Deposit date: | 2000-11-28 | Release date: | 2001-04-02 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The homing endonuclease I-CreI uses three metals, one of which is shared between the two active sites. Nat.Struct.Biol., 8, 2001
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1GE8
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1GFO
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![BU of 1gfo by Molmil](/molmil-images/mine/1gfo) | OMPF PORIN (MUTANT R132P) | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, MATRIX PORIN OUTER MEMBRANE PROTEIN F | Authors: | Lou, K.-L, Schirmer, T. | Deposit date: | 1996-05-08 | Release date: | 1996-12-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural and functional characterization of OmpF porin mutants selected for larger pore size. I. Crystallographic analysis. J.Biol.Chem., 271, 1996
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1GGX
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1GAH
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![BU of 1gah by Molmil](/molmil-images/mine/1gah) | GLUCOAMYLASE-471 COMPLEXED WITH ACARBOSE | Descriptor: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, GLUCOAMYLASE-471, alpha-D-mannopyranose, ... | Authors: | Aleshin, A.E, Stoffer, B, Firsov, L.M, Svensson, B, Honzatko, R.B. | Deposit date: | 1996-03-06 | Release date: | 1996-08-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystallographic complexes of glucoamylase with maltooligosaccharide analogs: relationship of stereochemical distortions at the nonreducing end to the catalytic mechanism. Biochemistry, 35, 1996
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1GFS
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![BU of 1gfs by Molmil](/molmil-images/mine/1gfs) | GDP-FUCOSE SYNTHETASE FROM E. COLI | Descriptor: | GDP-FUCOSE SYNTHETASE | Authors: | Somers, W.S, Stahl, M.L, Sullivan, F.X. | Deposit date: | 1998-08-17 | Release date: | 1999-08-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | GDP-fucose synthetase from Escherichia coli: structure of a unique member of the short-chain dehydrogenase/reductase family that catalyzes two distinct reactions at the same active site. Structure, 6, 1998
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1GG8
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![BU of 1gg8 by Molmil](/molmil-images/mine/1gg8) | DESIGN OF INHIBITORS OF GLYCOGEN PHOSPHORYLASE: A STUDY OF ALPHA-AND BETA-C-GLUCOSIDES AND 1-THIO-BETA-D-GLUCOSE COMPOUNDS | Descriptor: | ALPHA-D-GLUCOPYRANOSYL-2-CARBOXYLIC ACID AMIDE, INOSINIC ACID, PROTEIN (GLYCOGEN PHOSPHORYLASE), ... | Authors: | Watson, K.A, Mitchell, E.P, Johnson, L.N, Son, J.C, Bichard, C.J, Orchard, M.G, Fleet, G.W, Oikonomakos, N.G, Leonidas, D.D, Kontou, M, Papageorgiou, A.C. | Deposit date: | 2000-07-30 | Release date: | 2000-08-23 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Design of inhibitors of glycogen phosphorylase: a study of alpha- and beta-C-glucosides and 1-thio-beta-D-glucose compounds. Biochemistry, 33, 1994
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1FWA
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1GGT
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![BU of 1ggt by Molmil](/molmil-images/mine/1ggt) | THREE-DIMENSIONAL STRUCTURE OF A TRANSGLUTAMINASE: HUMAN BLOOD COAGULATION FACTOR XIII | Descriptor: | COAGULATION FACTOR XIII | Authors: | Yee, V.C, Pedersen, L.C, Trong, I.L, Bishop, P.D, Stenkamp, R.E, Teller, D.C. | Deposit date: | 1994-01-25 | Release date: | 1995-07-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Three-dimensional structure of a transglutaminase: human blood coagulation factor XIII. Proc.Natl.Acad.Sci.USA, 91, 1994
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1GKO
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![BU of 1gko by Molmil](/molmil-images/mine/1gko) | An Engineered Transthyretin Monomer that is Non-amyloidogenic - Unless Partially Denatured | Descriptor: | TRANSTHYRETIN | Authors: | Jiang, X, Smith, C.S, Petrassi, H.M, Hammarstrom, P, White, J.T, Sacchettini, J.C, Kelly, J.W. | Deposit date: | 2001-08-17 | Release date: | 2001-11-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | An Engineered Transthyretin Monomer that is Nonamyloidogenic, Unless It is Partially Denatured Biochemistry, 40, 2001
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1FV9
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1GKH
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![BU of 1gkh by Molmil](/molmil-images/mine/1gkh) | MUTANT K69H OF GENE V PROTEIN (SINGLE-STRANDED DNA BINDING PROTEIN) | Descriptor: | GENE V PROTEIN | Authors: | Su, S, Gao, Y.-G, Zhang, H, Terwilliger, T.C, Wang, A.H.-J. | Deposit date: | 1997-03-04 | Release date: | 1997-09-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Analyses of the stability and function of three surface mutants (R82C, K69H, and L32R) of the gene V protein from Ff phage by X-ray crystallography. Protein Sci., 6, 1997
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1GHA
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![BU of 1gha by Molmil](/molmil-images/mine/1gha) | A SECOND ACTIVE SITE IN CHYMOTRYPSIN? THE X-RAY CRYSTAL STRUCTURE OF N-ACETYL-D-TRYPTOPHAN BOUND TO GAMMA-CHYMOTRYPSIN | Descriptor: | GAMMA-CHYMOTRYPSIN A, ISOPROPYL ALCOHOL, PRO GLY VAL TYR PEPTIDE, ... | Authors: | Yennawar, H.P, Yennawar, N.H, Farber, G.K. | Deposit date: | 1994-04-06 | Release date: | 1994-06-22 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A STRUCTURAL EXPLANATION FOR ENZYME MEMORY IN NONAQUEOUS SOLVENTS. J.Am.Chem.Soc., 117, 1995
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1FTS
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1FV0
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![BU of 1fv0 by Molmil](/molmil-images/mine/1fv0) | FIRST STRUCTURAL EVIDENCE OF THE INHIBITION OF PHOSPHOLIPASE A2 BY ARISTOLOCHIC ACID: CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 AND ARISTOLOCHIC ACID | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 9-HYDROXY ARISTOLOCHIC ACID, ACETATE ION, ... | Authors: | Chandra, V, Jasti, J, Kaur, P, Srinivasan, A, Betzel, C, Singh, T.P. | Deposit date: | 2000-09-18 | Release date: | 2002-08-28 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Basis of Phospholipase A2 Inhibition for the Synthesis of Prostaglandins by the Plant Alkaloid Aristolochic Acid from a 1.7 A Crystal Structure Biochemistry, 41, 2002
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