1ZPE
| Arginase I covalently modified with butylamine at Q19C | Descriptor: | Arginase 1, MANGANESE (II) ION | Authors: | Colleluori, D.M, Reczkowski, R.S, Emig, F.A, Cama, E, Cox, J.D, Scolnick, L.R, Compher, K, Jude, K, Han, S, Viola, R.E, Christianson, D.W, Ash, D.E. | Deposit date: | 2005-05-16 | Release date: | 2005-12-06 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Probing the role of the hyper-reactive histidine residue of arginase. Arch.Biochem.Biophys., 444, 2005
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1D3V
| CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH 2(S)-AMINO-6-BORONOHEXANOIC ACID, AN L-ARGININE ANALOG | Descriptor: | 2(S)-AMINO-6-BORONOHEXANOIC ACID, MANGANESE (II) ION, PROTEIN (ARGINASE) | Authors: | Cox, J.D, Kim, N.N, Traish, A.M, Christianson, D.W. | Deposit date: | 1999-10-01 | Release date: | 1999-11-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Arginase-boronic acid complex highlights a physiological role in erectile function. Nat.Struct.Biol., 6, 1999
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1ZPG
| Arginase I covalently modified with propylamine at Q19C | Descriptor: | Arginase 1, MANGANESE (II) ION | Authors: | Colleluori, D.M, Reczkowski, R.S, Emig, F.A, Cama, E, Cox, J.D, Scolnick, L.R, Compher, K, Jude, K, Han, S, Viola, R.E, Christianson, D.W, Ash, D.E. | Deposit date: | 2005-05-16 | Release date: | 2005-12-06 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Probing the role of the hyper-reactive histidine residue of arginase. Arch.Biochem.Biophys., 444, 2005
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3E8Z
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1HQG
| CRYSTAL STRUCTURE OF THE H141C ARGINASE VARIANT COMPLEXED WITH PRODUCTS ORNITHINE AND UREA | Descriptor: | ARGINASE 1, L-ornithine, MANGANESE (II) ION, ... | Authors: | Cox, J.D, Cama, E, Colleluori, D.M, Ash, D.E, Christianson, D.W. | Deposit date: | 2000-12-16 | Release date: | 2001-04-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase. Biochemistry, 40, 2001
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1RLA
| THREE-DIMENSIONAL STRUCTURE OF RAT LIVER ARGINASE, THE BINUCLEAR MANGANESE METALLOENZYME OF THE UREA CYCLE | Descriptor: | ARGINASE, MANGANESE (II) ION | Authors: | Kanyo, Z, Scolnick, L, Ash, D, Christianson, D.W. | Deposit date: | 1996-08-15 | Release date: | 1997-10-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of a unique binuclear manganese cluster in arginase. Nature, 383, 1996
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3E9B
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1T4T
| arginase-dinor-NOHA complex | Descriptor: | 3-{[(E)-AMINO(HYDROXYIMINO)METHYL]AMINO}ALANINE, Arginase 1, MANGANESE (II) ION | Authors: | Cama, E, Pethe, S, Boucher, J.-L, Shoufa, H, Emig, F.A, Ash, D.E, Viola, R.E, Mansuy, D, Christianson, D.W. | Deposit date: | 2004-04-30 | Release date: | 2005-04-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Inhibitor coordination interactions in the binuclear manganese cluster of arginase Biochemistry, 43, 2004
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1T5F
| arginase I-AOH complex | Descriptor: | (S)-2-AMINO-7,7-DIHYDROXYHEPTANOIC ACID, Arginase 1, MANGANESE (II) ION | Authors: | Shin, H, Cama, E, Christianson, D.W. | Deposit date: | 2004-05-04 | Release date: | 2005-05-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Design of amino acid aldehydes as transition-state analogue inhibitors of arginase J.Am.Chem.Soc., 126, 2004
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1HQ5
| CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH S-(2-BORONOETHYL)-L-CYSTEINE, AN L-ARGININE ANALOGUE | Descriptor: | ARGINASE 1, MANGANESE (II) ION, S-2-(BORONOETHYL)-L-CYSTEINE | Authors: | Kim, N.N, Cox, J.D, Baggio, R.F, Emig, F.A, Mistry, S.K, Harper, S.L, Speicher, D.W, Morris Jr, S.M, Ash, D.E, Traish, A, Christianson, D.W. | Deposit date: | 2000-12-14 | Release date: | 2001-04-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Probing erectile function: S-(2-boronoethyl)-L-cysteine binds to arginase as a transition state analogue and enhances smooth muscle relaxation in human penile corpus cavernosum. Biochemistry, 40, 2001
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1T5G
| Arginase-F2-L-Arginine complex | Descriptor: | ARGININE, Arginase 1, FLUORIDE ION, ... | Authors: | Cama, E, Pethe, S, Boucher, J.-L, Han, S, Emig, F.A, Ash, D.E, Viola, R.E, Mansuy, D, Christianson, D.W. | Deposit date: | 2004-05-04 | Release date: | 2004-10-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Inhibitor coordination interactions in the binuclear manganese cluster of arginase Biochemistry, 43, 2004
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1P8R
| Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I. | Descriptor: | Arginase 1, CHLORIDE ION, MANGANESE (II) ION, ... | Authors: | Cama, E, Emig, F.A, Ash, D.E, Christianson, D.W. | Deposit date: | 2003-05-07 | Release date: | 2003-06-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and functional importance of first-shell metal ligands in the binuclear
manganese cluster of arginase I Biochemistry, 42, 2003
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1TA1
| H141C mutant of rat liver arginase I | Descriptor: | Arginase 1, GLYCEROL, MANGANESE (II) ION | Authors: | Cama, E, Cox, J.D, Ash, D.E, Christianson, D.W. | Deposit date: | 2004-05-19 | Release date: | 2005-08-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Probing the role of the hyper-reactive histidine residue of arginase. Arch.Biochem.Biophys., 444, 2005
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1P8P
| Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I. | Descriptor: | Arginase 1, MANGANESE (II) ION | Authors: | Cama, E, Emig, F.A, Ash, D.E, Christianson, D.W. | Deposit date: | 2003-05-07 | Release date: | 2003-06-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and functional importance of first-shell metal ligands in the binuclear
manganese cluster of arginase I Biochemistry, 42, 2003
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3RLA
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1T4P
| Arginase-dehydro-ABH complex | Descriptor: | Arginase 1, MANGANESE (II) ION, [(1E,5S)-5-AMINO-5-CARBOXYPENT-1-ENYL](TRIHYDROXY)BORATE(1-) | Authors: | Cama, E, Pethe, S, Boucher, J.-L, Han, S, Emig, F.A, Ash, D.E, Viola, R.E, Mansuy, D, Christianson, D.W. | Deposit date: | 2004-04-30 | Release date: | 2005-04-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Inhibitor coordination interactions in the binuclear manganese cluster of arginase Biochemistry, 43, 2004
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1T4R
| arginase-descarboxy-nor-NOHA complex | Descriptor: | 3-{[(E)-AMINO(HYDROXYIMINO)METHYL]AMINO}PROPAN-1-AMINIUM, Arginase 1, MANGANESE (II) ION | Authors: | Cama, E, Pethe, S, Boucher, J.-L, Shoufa, H, Emig, F.A, Ash, D.E, Viola, R.E, Mansuy, D, Christianson, D.W. | Deposit date: | 2004-04-30 | Release date: | 2005-04-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Inhibitor coordination interactions in the binuclear manganese cluster of arginase Biochemistry, 43, 2004
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1TBH
| H141D mutant of rat liver arginase I | Descriptor: | Arginase 1, MANGANESE (II) ION | Authors: | Cama, E, Cox, J.D, Ash, D.E, Christianson, D.W. | Deposit date: | 2004-05-20 | Release date: | 2005-08-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Probing the role of the hyper-reactive histidine residue of arginase. Arch.Biochem.Biophys., 444, 2005
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5RLA
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1HQH
| CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH NOR-N-HYDROXY-L-ARGININE | Descriptor: | ARGINASE 1, MANGANESE (II) ION, NOR-N-OMEGA-HYDROXY-L-ARGININE | Authors: | Cox, J.D, Cama, E, Colleluori, D.M, Ash, D.E, Christianson, D.W. | Deposit date: | 2000-12-16 | Release date: | 2001-04-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase. Biochemistry, 40, 2001
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1R1O
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1T4S
| arginase-L-valine complex | Descriptor: | Arginase 1, MANGANESE (II) ION, VALINE | Authors: | Cama, E, Pethe, S, Boucher, J.-L, Shoufa, H, Emig, F.A, Ash, D.E, Viola, R.E, Mansuy, D, Christianson, D.W. | Deposit date: | 2004-04-30 | Release date: | 2004-10-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Inhibitor coordination interactions in the binuclear manganese cluster of arginase Biochemistry, 43, 2004
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1TBJ
| H141A mutant of rat liver arginase I | Descriptor: | Arginase 1, GLYCEROL, MANGANESE (II) ION | Authors: | Cama, E, Cox, J.D, Ash, D.E, Christianson, D.W. | Deposit date: | 2004-05-20 | Release date: | 2005-08-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Probing the role of the hyper-reactive histidine residue of arginase. Arch.Biochem.Biophys., 444, 2005
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1P8M
| Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I. | Descriptor: | Arginase 1, MANGANESE (II) ION | Authors: | Cama, E, Emig, F.A, Ash, E.-D, Christianson, D.W. | Deposit date: | 2003-05-07 | Release date: | 2003-06-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase I. Biochemistry, 42, 2003
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3E8Q
| X-ray structure of rat arginase I-T135A: the unliganded complex | Descriptor: | Arginase-1, MANGANESE (II) ION | Authors: | Shishova, E.Y, Di Costanzo, L, Emig, F.A, Ash, D.E, Christianson, D.W. | Deposit date: | 2008-08-20 | Release date: | 2008-12-02 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Probing the specificity determinants of amino acid recognition by arginase. Biochemistry, 48, 2009
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