8IIP
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![BU of 8iip by Molmil](/molmil-images/mine/8iip) | |
8IIF
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![BU of 8iif by Molmil](/molmil-images/mine/8iif) | H109A mutant of uracil DNA glycosylase X | Descriptor: | GLYCEROL, IRON/SULFUR CLUSTER, Type-4 uracil-DNA glycosylase | Authors: | Aroli, S. | Deposit date: | 2023-02-24 | Release date: | 2023-06-21 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Mutational and structural analyses of UdgX: insights into the active site pocket architecture and its evolution. Nucleic Acids Res., 51, 2023
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8IIQ
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![BU of 8iiq by Molmil](/molmil-images/mine/8iiq) | MsmUdgX H109S/E52N double mutant | Descriptor: | IRON/SULFUR CLUSTER, Type-4 uracil-DNA glycosylase | Authors: | Aroli, S. | Deposit date: | 2023-02-24 | Release date: | 2023-06-21 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Mutational and structural analyses of UdgX: insights into the active site pocket architecture and its evolution. Nucleic Acids Res., 51, 2023
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8IIJ
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![BU of 8iij by Molmil](/molmil-images/mine/8iij) | H109G mutant of uracil DNA glycosylase X | Descriptor: | BETA-MERCAPTOETHANOL, IRON/SULFUR CLUSTER, Type-4 uracil-DNA glycosylase | Authors: | Aroli, S. | Deposit date: | 2023-02-24 | Release date: | 2023-06-21 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Mutational and structural analyses of UdgX: insights into the active site pocket architecture and its evolution. Nucleic Acids Res., 51, 2023
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8IIT
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![BU of 8iit by Molmil](/molmil-images/mine/8iit) | |
8III
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![BU of 8iii by Molmil](/molmil-images/mine/8iii) | |
8IIO
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![BU of 8iio by Molmil](/molmil-images/mine/8iio) | H109Q mutant of uracil DNA glycosylase X | Descriptor: | GLYCEROL, IRON/SULFUR CLUSTER, Type-4 uracil-DNA glycosylase | Authors: | Aroli, S. | Deposit date: | 2023-02-24 | Release date: | 2023-06-21 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Mutational and structural analyses of UdgX: insights into the active site pocket architecture and its evolution. Nucleic Acids Res., 51, 2023
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8IIN
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![BU of 8iin by Molmil](/molmil-images/mine/8iin) | |
8IIM
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![BU of 8iim by Molmil](/molmil-images/mine/8iim) | H109K mutant of uracil DNA glycosylase X | Descriptor: | BETA-MERCAPTOETHANOL, IRON/SULFUR CLUSTER, Type-4 uracil-DNA glycosylase | Authors: | Aroli, S. | Deposit date: | 2023-02-24 | Release date: | 2023-06-21 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Mutational and structural analyses of UdgX: insights into the active site pocket architecture and its evolution. Nucleic Acids Res., 51, 2023
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8IIE
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![BU of 8iie by Molmil](/molmil-images/mine/8iie) | |
8IIH
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![BU of 8iih by Molmil](/molmil-images/mine/8iih) | H109C mutant of uracil DNA glycosylase X | Descriptor: | IRON/SULFUR CLUSTER, Type-4 uracil-DNA glycosylase | Authors: | Aroli, S. | Deposit date: | 2023-02-24 | Release date: | 2023-06-21 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Mutational and structural analyses of UdgX: insights into the active site pocket architecture and its evolution. Nucleic Acids Res., 51, 2023
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8IIL
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![BU of 8iil by Molmil](/molmil-images/mine/8iil) | |
8IIS
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![BU of 8iis by Molmil](/molmil-images/mine/8iis) | MsmUdgX H109S/R184A double mutant | Descriptor: | IRON/SULFUR CLUSTER, Type-4 uracil-DNA glycosylase | Authors: | Aroli, S. | Deposit date: | 2023-02-24 | Release date: | 2023-06-21 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Mutational and structural analyses of UdgX: insights into the active site pocket architecture and its evolution. Nucleic Acids Res., 51, 2023
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8IIG
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![BU of 8iig by Molmil](/molmil-images/mine/8iig) | |
8IIR
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![BU of 8iir by Molmil](/molmil-images/mine/8iir) | MsmUdgX H109S/Q53A double mutant | Descriptor: | BETA-MERCAPTOETHANOL, IRON/SULFUR CLUSTER, Type-4 uracil-DNA glycosylase | Authors: | Aroli, S. | Deposit date: | 2023-02-24 | Release date: | 2023-06-21 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Mutational and structural analyses of UdgX: insights into the active site pocket architecture and its evolution. Nucleic Acids Res., 51, 2023
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8I6C
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![BU of 8i6c by Molmil](/molmil-images/mine/8i6c) | Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with 6-Formyl-uracil, Form III | Descriptor: | 6-[bis(oxidanyl)methyl]-5~{H}-pyrimidine-2,4-dione, Uracil-DNA glycosylase | Authors: | Raj, P, Paul, A, Gopal, B. | Deposit date: | 2023-01-27 | Release date: | 2023-07-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment. Eur.J.Med.Chem., 258, 2023
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8I62
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![BU of 8i62 by Molmil](/molmil-images/mine/8i62) | Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with Barbituric acid, Form I | Descriptor: | 1,2-ETHANEDIOL, BARBITURIC ACID, CHLORIDE ION, ... | Authors: | Raj, P, Paul, A, Gopal, B. | Deposit date: | 2023-01-27 | Release date: | 2023-07-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.26 Å) | Cite: | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment. Eur.J.Med.Chem., 258, 2023
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8I61
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![BU of 8i61 by Molmil](/molmil-images/mine/8i61) | Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with Barbituric acid and Citric acid, Form I | Descriptor: | 1,2-ETHANEDIOL, BARBITURIC ACID, CITRIC ACID, ... | Authors: | Raj, P, Paul, A, Gopal, B. | Deposit date: | 2023-01-27 | Release date: | 2023-07-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.24 Å) | Cite: | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment. Eur.J.Med.Chem., 258, 2023
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8I66
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![BU of 8i66 by Molmil](/molmil-images/mine/8i66) | Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with isoorotic acid (2,4-Dihydroxypyrimidine-5-carboxylic Acid) and citric acid, Form I | Descriptor: | 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid, CITRIC ACID, Uracil-DNA glycosylase | Authors: | Raj, P, Paul, A, Gopal, B. | Deposit date: | 2023-01-27 | Release date: | 2023-07-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment. Eur.J.Med.Chem., 258, 2023
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8I67
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![BU of 8i67 by Molmil](/molmil-images/mine/8i67) | Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with 2,4-Thiazolidinedione, Form I | Descriptor: | 1,2-ETHANEDIOL, 1,3-thiazolidine-2,4-dione, Uracil-DNA glycosylase | Authors: | Raj, P, Paul, A, Gopal, B. | Deposit date: | 2023-01-27 | Release date: | 2023-07-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment. Eur.J.Med.Chem., 258, 2023
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8I64
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![BU of 8i64 by Molmil](/molmil-images/mine/8i64) | Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with Barbituric acid, Form II | Descriptor: | 1,2-ETHANEDIOL, BARBITURIC ACID, Uracil-DNA glycosylase | Authors: | Raj, P, Paul, A, Gopal, B. | Deposit date: | 2023-01-27 | Release date: | 2023-07-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment. Eur.J.Med.Chem., 258, 2023
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8I63
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![BU of 8i63 by Molmil](/molmil-images/mine/8i63) | Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with Barbituric acid, Form III | Descriptor: | 1,2-ETHANEDIOL, BARBITURIC ACID, Uracil-DNA glycosylase | Authors: | Raj, P, Paul, A, Gopal, B. | Deposit date: | 2023-01-27 | Release date: | 2023-07-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment. Eur.J.Med.Chem., 258, 2023
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8I65
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![BU of 8i65 by Molmil](/molmil-images/mine/8i65) | Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with isoorotic acid (2,4-Dihydroxypyrimidine-5-carboxylic Acid), Form I | Descriptor: | 1,2-ETHANEDIOL, 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid, Uracil-DNA glycosylase | Authors: | Raj, P, Paul, A, Gopal, B. | Deposit date: | 2023-01-27 | Release date: | 2023-07-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment. Eur.J.Med.Chem., 258, 2023
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8I68
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![BU of 8i68 by Molmil](/molmil-images/mine/8i68) | Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with Uric acid, Form III | Descriptor: | 1,2-ETHANEDIOL, URIC ACID, Uracil-DNA glycosylase | Authors: | Raj, P, Paul, A, Gopal, B. | Deposit date: | 2023-01-27 | Release date: | 2023-07-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment. Eur.J.Med.Chem., 258, 2023
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8I6A
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![BU of 8i6a by Molmil](/molmil-images/mine/8i6a) | Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with Orotic acid, Form III | Descriptor: | 1,2-ETHANEDIOL, OROTIC ACID, Uracil-DNA glycosylase | Authors: | Raj, P, Paul, A, Gopal, B. | Deposit date: | 2023-01-27 | Release date: | 2023-07-12 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of non-uracil ring fragments in complex with Mycobacterium tuberculosis uracil DNA glycosylase (MtUng) as a starting point for novel inhibitor design: A case study with the barbituric acid fragment. Eur.J.Med.Chem., 258, 2023
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