PDB: 52677 resultsInfo pagesStatus searchChemie searchBIRD

---

4OK5	Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Compound 9 [1-(3-ethynylbenzyl)-1H-indol-3-yl]acetic acid] Descriptor: CALCIUM ION, Serine protease NS3, [1-(3-ethynylbenzyl)-1H-indol-3-yl]acetic acid Authors: Padyana, A.K. Deposit date: 2014-01-21 Release date: 2014-03-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Integrated strategies for identifying leads that target the NS3 helicase of the hepatitis C virus. J.Med.Chem., 57, 2014
1B11	STRUCTURE OF FELINE IMMUNODEFICIENCY VIRUS PROTEASE COMPLEXED WITH TL-3-093 Descriptor: PROTEIN (Feline Immunodeficiency Virus PROTEASE), SULFATE ION, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate Authors: Gustchina, A, Li, M, Wlodawer, A. Deposit date: 1998-11-25 Release date: 1998-12-02 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural studies of FIV and HIV-1 proteases complexed with an efficient inhibitor of FIV protease Proteins, 38, 2000
4OJQ	Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Fragment 1 [(5-bromo-1H-indol-3-yl)acetic acid] Descriptor: (5-bromo-1H-indol-3-yl)acetic acid, CALCIUM ION, Serine protease NS3 Authors: Padyana, A.K. Deposit date: 2014-01-21 Release date: 2014-03-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Integrated strategies for identifying leads that target the NS3 helicase of the hepatitis C virus. J.Med.Chem., 57, 2014
4OO1	Structure of an Rrp6-RNA exosome complex bound to poly(A) RNA Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Exosome complex component CSL4, ... Authors: Lima, C.D, Wasmuth, E.V. Deposit date: 2014-01-29 Release date: 2014-07-02 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structure of an Rrp6-RNA exosome complex bound to poly(A) RNA. Nature, 511, 2014
1AZI	MYOGLOBIN (HORSE HEART) RECOMBINANT WILD-TYPE COMPLEXED WITH AZIDE Descriptor: AZIDE ION, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Maurus, R, Brayer, G.D. Deposit date: 1997-10-11 Release date: 1998-02-25 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural and spectroscopic studies of azide complexes of horse heart myoglobin and the His-64-->Thr variant. Biochem.J., 332, 1998
4OYO	Human solAC Complexed with 4-(2-Chlorophenyl)-3-methyl-1H-pyrazole Descriptor: 4-(2-chlorophenyl)-5-methyl-1H-pyrazole, Adenylate cyclase type 10, GLYCEROL Authors: Vinkovic, M. Deposit date: 2014-02-12 Release date: 2014-04-02 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket. Chemmedchem, 9, 2014
4OZ3	Human solAC Complexed with 4-phenyl-3-(trifluoromethyl)-1H-pyrazole Descriptor: 4-phenyl-3-(trifluoromethyl)-1H-pyrazole, Adenylate cyclase type 10, GLYCEROL Authors: Vinkovic, M. Deposit date: 2014-02-13 Release date: 2014-04-02 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket. Chemmedchem, 9, 2014
4OYB	Crystal Structure Analysis of the solAC Descriptor: Adenylate cyclase type 10, GLYCEROL, ethyl 2-[3-[(4-azanyl-1,2,5-oxadiazol-3-yl)carbonyl]phenoxy]ethanoate Authors: Vinkovic, M. Deposit date: 2014-02-11 Release date: 2014-04-02 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structure of human soluble adenylate cyclase reveals a distinct, highly flexible allosteric bicarbonate binding pocket. Chemmedchem, 9, 2014
4OKS	Crystal Structure of Hepatitis C Virus NS3 Helicase Inhibitor Co-complex with Compound 19 [[6-(3,5-diaminophenyl)-1-(2-methoxy-5-nitrobenzyl)-1H-indol-3-yl]acetic acid] Descriptor: CALCIUM ION, Serine protease NS3, [6-(3,5-diaminophenyl)-1-(2-methoxy-5-nitrobenzyl)-1H-indol-3-yl]acetic acid Authors: Padyana, A.K. Deposit date: 2014-01-22 Release date: 2014-03-05 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Integrated strategies for identifying leads that target the NS3 helicase of the hepatitis C virus. J.Med.Chem., 57, 2014
1B10	SOLUTION NMR STRUCTURE OF RECOMBINANT SYRIAN HAMSTER PRION PROTEIN RPRP(90-231) , 25 STRUCTURES Descriptor: PROTEIN (PRION PROTEIN) Authors: James, T.L, Liu, H, Ulyanov, N.B, Farr-Jones, S. Deposit date: 1998-11-25 Release date: 1998-12-02 Last modified: 2023-12-27 Method: SOLUTION NMR Cite: Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform. Proc.Natl.Acad.Sci.USA, 94, 1997
1B4I	Control of K+ Channel Gating by protein phosphorylation: structural switches of the inactivation gate, NMR, 22 structures Descriptor: POTASSIUM CHANNEL Authors: Antz, C, Bauer, T, Kalbacher, H, Frank, R, Covarrubias, M, Kalbitzer, H.R, Ruppersberg, J.P, Baukrowitz, T, Fakler, B. Deposit date: 1998-12-22 Release date: 1999-04-27 Last modified: 2022-03-23 Method: SOLUTION NMR Cite: Control of K+ channel gating by protein phosphorylation: structural switches of the inactivation gate. Nat.Struct.Biol., 6, 1999
4A3I	RNA Polymerase II binary complex with DNA Descriptor: 5'-D(*GP*GP*CP*AP*CP*AP*AP*CP*TP*GP*CP*GP*GP*CP*T)-3', DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, ... Authors: Cheung, A.C.M, Sainsbury, S, Cramer, P. Deposit date: 2011-09-30 Release date: 2012-02-08 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.8 Å) Cite: Structural basis of initial RNA polymerase II transcription. EMBO J., 30, 2011
4A3J	RNA Polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid and soaked with GMPCPP Descriptor: 5'-D(*AP*GP*CP*TP*AP*GP*CP*TP*TP*TP*CP*BRUP*AP*CP*CP *TP*GP*AP*AP*CP*AP*AP*CP*TP*AP*AP*CP)-3', 5'-D(*GP*TP*AP*GP*AP*AP*AP*GP*CP*TP*AP*GP*CP*TP)-3', 5'-R(*CP*AP)-3', ... Authors: Cheung, A.C.M, Sainsbury, S, Cramer, P. Deposit date: 2011-09-30 Release date: 2011-12-07 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.7 Å) Cite: Structural Basis of Initial RNA Polymerase II Transcription. Embo J., 30, 2011
3BI0	X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a transition state analog of Glu-Glu Descriptor: (2S)-2-{[(S)-[(3S)-3-amino-3-carboxypropyl](hydroxy)phosphoryl]methyl}pentanedioic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Lubkowski, J, Barinka, C. Deposit date: 2007-11-29 Release date: 2008-01-08 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.67 Å) Cite: Structural basis of interactions between human glutamate carboxypeptidase II and its substrate analogs J.Mol.Biol., 376, 2008
8U1U	Structure of a class A GPCR/agonist complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C-C motif chemokine 1,C-C chemokine receptor type 8,EGFP fusion protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Sun, D, Johnson, M, Masureel, M. Deposit date: 2023-09-02 Release date: 2023-12-20 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8. Nat Commun, 14, 2023
4OTN	Crystal structure of the C-terminal regulatory domain of murine GCN2 Descriptor: 1,2-ETHANEDIOL, Eukaryotic translation initiation factor 2-alpha kinase 4, SULFATE ION Authors: He, H, Georgiadis, M.M. Deposit date: 2014-02-13 Release date: 2014-04-16 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal Structures of GCN2 Protein Kinase C-terminal Domains Suggest Regulatory Differences in Yeast and Mammals. J.Biol.Chem., 289, 2014
8U4O	Structure of CXCL12-bound CXCR4/Gi complex Descriptor: C-X-C chemokine receptor type 4, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Saotome, K, McGoldrick, L.L, Franklin, M.C. Deposit date: 2023-09-11 Release date: 2024-03-13 Method: ELECTRON MICROSCOPY (3.29 Å) Cite: Structural insights into CXCR4 modulation and oligomerization Biorxiv, 2024
6V11	Lon Protease from Yersinia pestis Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease Authors: Shin, M, Puchades, C, Asmita, A, Puri, N, Adjei, E, Wiseman, R.L, Karzai, A.W, Lander, G.C. Deposit date: 2019-11-19 Release date: 2020-01-22 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structural basis for distinct operational modes and protease activation in AAA+ protease Lon. Sci Adv, 6, 2020
3CJS	Minimal Recognition Complex between PrmA and Ribosomal Protein L11 Descriptor: 1,2-ETHANEDIOL, 50S ribosomal protein L11, Ribosomal protein L11 methyltransferase Authors: Demirci, H, Gregory, S.T, Dahlberg, A.E, Jogl, G. Deposit date: 2008-03-13 Release date: 2008-05-20 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.37 Å) Cite: Multiple-Site Trimethylation of Ribosomal Protein L11 by the PrmA Methyltransferase. Structure, 16, 2008
1DZ5	The NMR structure of the 38KDa U1A protein-PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein Descriptor: PIE, RNA (5'-R(*GP*AP*GP*AP*CP*AP*UP*UP*GP*CP*AP*CP*CP* CP*GP*GP*AP*GP*UP*CP*UP*C)-3'), U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A Authors: Varani, L, Gunderson, S.I, Mattaj, I.W, Kay, L.E, Neuhaus, D, Varani, G. Deposit date: 2000-02-16 Release date: 2000-03-29 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: The NMR Structure of the 38kDa U1A Protein-Pie RNA Complex Reveals the Basis of Cooperativity in Regulation of Polyadenylation by Human U1A Protein Nat.Struct.Biol., 7, 2000
4A3C	RNA Polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... Authors: Cheung, A.C.M, Sainsbury, S, Cramer, P. Deposit date: 2011-09-30 Release date: 2011-11-16 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Structural basis of initial RNA polymerase II transcription. EMBO J., 30, 2011
4A3D	RNA Polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... Authors: Cheung, A.C.M, Sainsbury, S, Cramer, P. Deposit date: 2011-09-30 Release date: 2011-12-07 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Structural basis of initial RNA polymerase II transcription. EMBO J., 30, 2011
4A3K	RNA Polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid Descriptor: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*DTP *TP*TP*CP*CP*BRU*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP)-3', 5'-R(*AP*CP*CP*AP*GP*GP*AP)-3', ... Authors: Cheung, A.C.M, Sainsbury, S, Cramer, P. Deposit date: 2011-09-30 Release date: 2011-12-07 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Structural Basis of Initial RNA Polymerase II Transcription. Embo J., 30, 2011
4A3G	RNA Polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... Authors: Cheung, A.C.M, Sainsbury, S, Cramer, P. Deposit date: 2011-09-30 Release date: 2012-02-08 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Structural basis of initial RNA polymerase II transcription. EMBO J., 30, 2011
1DWX	MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DIMER N-hydroxyarginine and tetrahydrobiopterin Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, N-OMEGA-HYDROXY-L-ARGININE, NITRIC OXIDE SYNTHASE, ... Authors: Crane, B.R, Arvai, A.S, Getzoff, E.D, Stuehr, D.J, Tainer, J.A. Deposit date: 1999-12-14 Release date: 2000-02-06 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structures of the N(Omega)-Hydroxy-L-Arginine Complex of Inducible Nitric Oxide Synthase Oxygenase Dimer with Active Andinactive Pterins Biochemistry, 39, 2000

<975976977978979980981982983984985986987988989990>