5HNY
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![BU of 5hny by Molmil](/molmil-images/mine/5hny) | Structural basis of backwards motion in kinesin-14: plus-end directed nKn669 in the AMPPNP state | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Shigematsu, H, Yokoyama, T, Kikkawa, M, Shirouzu, M, Nitta, R. | Deposit date: | 2016-01-19 | Release date: | 2016-08-10 | Last modified: | 2016-11-02 | Method: | ELECTRON MICROSCOPY (6.3 Å) | Cite: | Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility Structure, 24, 2016
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3L71
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![BU of 3l71 by Molmil](/molmil-images/mine/3l71) | Cytochrome BC1 complex from chicken with azoxystrobin bound | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CARDIOLIPIN, Coenzyme Q10, ... | Authors: | Huang, L, Berry, E.A. | Deposit date: | 2009-12-27 | Release date: | 2010-02-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.84 Å) | Cite: | Famoxadone and related inhibitors bind like methoxy acrylate inhibitors in the Qo site of the BC1 compl and fix the rieske iron-sulfur protein in a positio close to but distinct from that seen with stigmatellin and other "DISTAL" Qo inhibitors. To be Published
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5HOB
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![BU of 5hob by Molmil](/molmil-images/mine/5hob) | p73 homo-tetramerization domain mutant I | Descriptor: | MAGNESIUM ION, Tumor protein p73 | Authors: | Coutandin, D, Krojer, T, Salah, E, Mathea, S, Knapp, S, Dotsch, V. | Deposit date: | 2016-01-19 | Release date: | 2016-10-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.220013 Å) | Cite: | Structural basis of p63/p73 hetero-tetramerization To Be Published
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5HAC
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![BU of 5hac by Molmil](/molmil-images/mine/5hac) | Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 2.95 A resolution | Descriptor: | Proliferating cell nuclear antigen | Authors: | Singh, P.K, Yadav, S.P, Sharma, P, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2015-12-30 | Release date: | 2016-03-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal structure of Proliferating Cell Nuclear Antigen from Leishmania donovani at 2.95 A resolution To Be Published
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5HOQ
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![BU of 5hoq by Molmil](/molmil-images/mine/5hoq) | Apo structure of CalS11, TDP-rhamnose 3'-o-methyltransferase, an enzyme in Calicheamicin biosynthesis | Descriptor: | SULFATE ION, TDP-rhamnose 3'-O-methyltransferase (CalS11) | Authors: | Han, L, Helmich, K.E, Singh, S, Thorson, J.S, Bingman, C.A, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis | Deposit date: | 2016-01-19 | Release date: | 2016-03-30 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.793 Å) | Cite: | Loop dynamics of thymidine diphosphate-rhamnose 3'-O-methyltransferase (CalS11), an enzyme in calicheamicin biosynthesis. Struct Dyn., 3, 2016
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3L9H
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![BU of 3l9h by Molmil](/molmil-images/mine/3l9h) | X-ray structure of mitotic kinesin-5 (KSP, KIF11, Eg5)in complex with the hexahydro-2H-pyrano[3,2-c]quinoline EMD 534085 | Descriptor: | 1-[2-(dimethylamino)ethyl]-3-{[(2R,4aS,5R,10bS)-5-phenyl-9-(trifluoromethyl)-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinolin-2-yl]methyl}urea, ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF11 | Authors: | Knoechel, T. | Deposit date: | 2010-01-05 | Release date: | 2010-03-02 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. Bioorg.Med.Chem.Lett., 20, 2010
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5HB0
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![BU of 5hb0 by Molmil](/molmil-images/mine/5hb0) | |
3LDT
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![BU of 3ldt by Molmil](/molmil-images/mine/3ldt) | |
5HPQ
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3LE1
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![BU of 3le1 by Molmil](/molmil-images/mine/3le1) | |
5HC1
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3LEF
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![BU of 3lef by Molmil](/molmil-images/mine/3lef) | Crystal structure of HIV epitope-scaffold 4E10_S0_1Z6NA_001 | Descriptor: | 1,2-ETHANEDIOL, Uncharacterized protein 4E10_S0_1Z6NA_001 (T18) | Authors: | Holmes, M.A. | Deposit date: | 2010-01-14 | Release date: | 2010-09-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope. Structure, 18, 2010
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5HCB
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![BU of 5hcb by Molmil](/molmil-images/mine/5hcb) | Globular Domain of the Entamoeba histolytica calreticulin in complex with glucose | Descriptor: | CALCIUM ION, CHLORIDE ION, Calreticulin, ... | Authors: | Moreau, C.P, Cioci, G, Ianello, M, Laffly, E, Chouquet, A, Ferreira, A, Thielens, N.M, Gaboriaud, C. | Deposit date: | 2016-01-04 | Release date: | 2016-08-31 | Last modified: | 2017-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structures of parasite calreticulins provide insights into their flexibility and dual carbohydrate/peptide-binding properties. IUCrJ, 3, 2016
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3LAN
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![BU of 3lan by Molmil](/molmil-images/mine/3lan) | Crystal structure of HIV-1 reverse transcriptase in complex with N1-butyl pyrimidinedione non-nucleoside inhibitor | Descriptor: | 3-{[3-butyl-5-(1-methylethyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl]carbonyl}-5-methylbenzonitrile, HIV Reverse transcriptase, SULFATE ION | Authors: | Lansdon, E.B, Mitchell, M.L. | Deposit date: | 2010-01-06 | Release date: | 2010-02-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | N1-Alkyl pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Bioorg.Med.Chem.Lett., 20, 2010
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5HPY
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![BU of 5hpy by Molmil](/molmil-images/mine/5hpy) | Crystal Structure of RhoA.GDP.MgF3-in complex with human Myosin 9b RhoGAP domain | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, TRIFLUOROMAGNESATE, ... | Authors: | Yi, F.S, Ren, J.Q, Feng, W. | Deposit date: | 2016-01-21 | Release date: | 2016-07-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Noncanonical Myo9b-RhoGAP Accelerates RhoA GTP Hydrolysis by a Dual-Arginine-Finger Mechanism J.Mol.Biol., 428, 2016
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3LEM
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![BU of 3lem by Molmil](/molmil-images/mine/3lem) | |
5HCL
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![BU of 5hcl by Molmil](/molmil-images/mine/5hcl) | Crystal Structure of the first bromodomain of BRD4 in complex with DMA | Descriptor: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ~{N},~{N}-dimethylethanamide | Authors: | Dong, J, Weber, F.E, Caflisch, A. | Deposit date: | 2016-01-04 | Release date: | 2017-01-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | N,N Dimethylacetamide a drug excipient that acts as bromodomain ligand for osteoporosis treatment. Sci Rep, 7, 2017
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3LB8
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5HQH
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![BU of 5hqh by Molmil](/molmil-images/mine/5hqh) | 1.32 Angstrom Crystal Structure of Ybbr like Domain of lmo2119 Protein from Listeria monocytogenes. | Descriptor: | CHLORIDE ION, Lmo2119 protein, SULFATE ION | Authors: | Minasov, G, Shuvalova, L, Dubrovska, I, Winsor, J, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-01-21 | Release date: | 2016-02-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | 1.32 Angstrom Crystal Structure of Ybbr like Domain of lmo2119 Protein from Listeria monocytogenes. To Be Published
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5HQQ
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![BU of 5hqq by Molmil](/molmil-images/mine/5hqq) | DNA duplex containing a ribonolactone lesion | Descriptor: | DNA (5'-D(*CP*GP*CP*TP*CP*(RIB)P*CP*AP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*(8OG)P*TP*GP*GP*GP*AP*GP*CP*G)-3') | Authors: | Zalesak, J, Constant, J.F, Jourdan, M. | Deposit date: | 2016-01-22 | Release date: | 2016-09-14 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Nuclear Magnetic Resonance Solution Structure of DNA Featuring Clustered 2'-Deoxyribonolactone and 8-Oxoguanine Lesions. Biochemistry, 55, 2016
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3LC4
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5HRB
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![BU of 5hrb by Molmil](/molmil-images/mine/5hrb) | The crystal structure of AsfvPolX:DNA1 binary complex | Descriptor: | BETA-MERCAPTOETHANOL, DNA (5'-D(*CP*GP*GP*AP*TP*AP*TP*CP*C)-3'), DNA polymerase beta-like protein, ... | Authors: | Chen, Y.Q, Zhang, J, Gan, J.H. | Deposit date: | 2016-01-23 | Release date: | 2017-01-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The crystal structure of Se-AsfvPolX(L52/163M mutant) in complex with 1nt-gap DNA1 To Be Published
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6YB9
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![BU of 6yb9 by Molmil](/molmil-images/mine/6yb9) | Human octameric PAICS in complex with SAICAR, AMP-PNP, and magnesium | Descriptor: | (2~{S})-2-[[5-azanyl-1-[(2~{R},3~{R},4~{S},5~{R})-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]imidazol-4-yl]car bonylamino]butanedioic acid, 1,2-ETHANEDIOL, MAGNESIUM ION, ... | Authors: | Skerlova, J, Unterlass, J, Gottmann, M, Homan, E, Helleday, T, Jemth, A.S, Stenmark, P. | Deposit date: | 2020-03-16 | Release date: | 2020-07-08 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.406 Å) | Cite: | Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target. J.Biol.Chem., 295, 2020
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5HRH
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3LCM
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![BU of 3lcm by Molmil](/molmil-images/mine/3lcm) | Crystal structure of Smu.1420 from Streptococcus mutans UA159 | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative oxidoreductase | Authors: | Wang, Z.X, Su, X.-D. | Deposit date: | 2010-01-11 | Release date: | 2011-01-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.799 Å) | Cite: | Structural and biochemical characterization of MdaB from cariogenic Streptococcus mutans reveals an NADPH-specific quinone oxidoreductase Acta Crystallogr.,Sect.D, 70, 2014
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