PDB: 13252 resultsInfo pagesStatus searchChemie searchBIRD

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7X6V	lymphocytic choriomeningitis virus polymerase- Matrix Z Protein Complex (LCMV L-Z Complex) Descriptor: MANGANESE (II) ION, RING finger protein Z, RNA-directed RNA polymerase L, ... Authors: Liu, L, Lou, Z. Deposit date: 2022-03-08 Release date: 2023-09-13 Last modified: 2023-09-27 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structure basis for allosteric regulation of lymphocytic choriomeningitis virus polymerase function by Z matrix protein. Protein Cell, 14, 2023
1N38	reovirus polymerase lambda3 elongation complex with one phosphodiester bond formed Descriptor: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, 3'-DEOXY-URIDINE 5'-TRIPHOSPHATE, 5'-R(*AP*UP*UP*AP*GP*C)-3', ... Authors: Tao, Y, Farsetta, D.L, Nibert, M.L, Harrison, S.C. Deposit date: 2002-10-25 Release date: 2002-12-25 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.8 Å) Cite: RNA Synthesis in a Cage--Structural Studies of Reovirus Polymerase [lambda] 3 Cell(Cambridge,Mass.), 111, 2002
1N1H	Initiation complex of polymerase lambda3 from reovirus Descriptor: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, 5'-R(*AP*UP*UP*AP*GP*C)-3', ... Authors: Tao, Y, Farsetta, D.L, Nibert, M.L, Harrison, S.C. Deposit date: 2002-10-17 Release date: 2002-12-25 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.8 Å) Cite: RNA Synthesis in a Cage--Structural Studies of Reovirus Polymerase [lambda] 3 Cell(Cambridge,Mass.), 111, 2002
8CBM	Structure of human mitochondrial CCA-adding enzyme in complex with mitochondrial pre-tRNA-Ile Descriptor: 3-hydroxyacyl-CoA dehydrogenase type-2, CCA tRNA nucleotidyltransferase 1, mitochondrial, ... Authors: MEYNIER, V, HARDWICK, S, CATALA, M, ROSKE, J, OERUM, S, CHIRGADZE, D, BARRAUD, P, LUISI, B, TISNE, C. Deposit date: 2023-01-25 Release date: 2024-06-12 Method: ELECTRON MICROSCOPY (3.14 Å) Cite: Structural basis for human mitochondrial tRNA maturation. Nat Commun, 15, 2024
7ORN	La Crosse virus polymerase at replication initiation stage Descriptor: ADENOSINE-5'-TRIPHOSPHATE, La Crosse virus polymerase, MAGNESIUM ION, ... Authors: Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H. Deposit date: 2021-06-06 Release date: 2022-02-16 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. Nat Commun, 13, 2022
8IZL	Structure of the Mumps Virus L Protein Bound by Phosphoprotein Tetramer Descriptor: Phosphoprotein, RNA-directed RNA polymerase L, ZINC ION Authors: Li, T.H, Shen, Q.T. Deposit date: 2023-04-07 Release date: 2024-04-17 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (2.93 Å) Cite: Structures of the mumps virus polymerase complex via cryo-electron microscopy. Nat Commun, 15, 2024
8CYF	WhiB3 bound to SigmaAr4-RNAP Beta flap tip chimera and DNA Descriptor: CACODYLATE ION, DNA (5'-D(*CP*AP*CP*CP*AP*CP*AP*AP*CP*CP*GP*AP*TP*TP*TP*T)-3'), DNA (5'-D(*GP*AP*AP*AP*AP*TP*CP*GP*GP*TP*TP*GP*TP*GP*GP*T)-3'), ... Authors: Wan, T, Zhang, L.M. Deposit date: 2022-05-23 Release date: 2023-05-17 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.44 Å) Cite: Structural basis of DNA binding by the WhiB-like transcription factor WhiB3 in Mycobacterium tuberculosis. J.Biol.Chem., 299, 2023
6FXC	The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Matzov, D, Aibara, S, Zimmerman, E, Bashan, A, Kidmose, R, Amunts, A, Yonath, A. Deposit date: 2018-03-08 Release date: 2018-03-21 Last modified: 2018-11-21 Method: ELECTRON MICROSCOPY (6.76 Å) Cite: The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus. Nat Commun, 8, 2017
6FHI	Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 19-mer serine 5 phosphorylated Pol II CTD peptide with a truncated linker. Descriptor: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ... Authors: Lukarska, M, Cusack, S. Deposit date: 2018-01-14 Release date: 2019-01-30 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Towards New Anti-Influenza Therapeutics: Structure-Activity Relationships in the Interaction between Heterotrimeric Influenza Polymerase and Pol II C-terminal domain To Be Published
4G7O	Crystal structure of Thermus thermophilus transcription initiation complex containing 2 nt of RNA Descriptor: 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', 5'-R(*GP*A)-3', ... Authors: Zhang, Y, Ebright, R.H. Deposit date: 2012-07-20 Release date: 2012-10-31 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.993 Å) Cite: Structural basis of transcription initiation. Science, 338, 2012
6DVB	Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 5nt spacer Descriptor: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Lin, W, Das, K, Feng, Y, Ebright, R.H. Deposit date: 2018-06-23 Release date: 2019-02-20 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.8 Å) Cite: Structural basis of ECF-sigma-factor-dependent transcription initiation. Nat Commun, 10, 2019
6DV9	Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 4nt spacer Descriptor: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Lin, W, Das, K, Feng, Y, Ebright, R.H. Deposit date: 2018-06-23 Release date: 2019-02-20 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.8 Å) Cite: Structural basis of ECF-sigma-factor-dependent transcription initiation. Nat Commun, 10, 2019
7YET	The structure of EBOV L-VP35 in complex with suramin Descriptor: 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, Polymerase cofactor VP35, RNA-directed RNA polymerase L Authors: Shi, Y, Yuan, B, Peng, Q. Deposit date: 2022-07-06 Release date: 2022-10-05 Last modified: 2024-07-03 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structure of the Ebola virus polymerase complex. Nature, 610, 2022
5HR7	X-ray crystal structure of C118A RlmN from Escherichia coli with cross-linked in vitro transcribed tRNA Descriptor: 5'-DEOXYADENOSINE, Dual-specificity RNA methyltransferase RlmN, IRON/SULFUR CLUSTER, ... Authors: Schwalm, E.L, Grove, T.L, Booker, S.J, Boal, A.K. Deposit date: 2016-01-22 Release date: 2016-04-13 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystallographic capture of a radical S-adenosylmethionine enzyme in the act of modifying tRNA. Science, 352, 2016
6FHH	Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 22-mer modified Pol II CTD peptide with serine 5 thiophosphorylated. Descriptor: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ... Authors: Lukarska, M, Cusack, S. Deposit date: 2018-01-14 Release date: 2019-01-30 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Towards New Anti-Influenza Therapeutics: Structure-Activity Relationships in the Interaction between Heterotrimeric Influenza Polymerase and Pol II C-terminal domain To Be Published
6DVC	Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 6nt spacer Descriptor: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Lin, W, Das, K, Feng, Y, Ebright, R.H. Deposit date: 2018-06-23 Release date: 2019-02-20 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structural basis of ECF-sigma-factor-dependent transcription initiation. Nat Commun, 10, 2019
5UH6	Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 2ntRNA in complex with Rifampin Descriptor: DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Lin, W, Das, K, Feng, Y, Ebright, R.H. Deposit date: 2017-01-11 Release date: 2017-04-12 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (3.837 Å) Cite: Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
5UH8	Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 4nt RNA Descriptor: DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Lin, W, Das, K, Feng, Y, Ebright, R.H. Deposit date: 2017-01-11 Release date: 2017-04-12 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (4.176 Å) Cite: Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
5UH9	Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 2nt RNA Descriptor: DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Lin, W, Das, K, Feng, Y, Ebright, R.H. Deposit date: 2017-01-11 Release date: 2017-04-12 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (4.402 Å) Cite: Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
5UHC	Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3nt RNA in complex with Rifampin Descriptor: DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... Authors: Lin, W, Das, K, Feng, Y, Ebright, R.H. Deposit date: 2017-01-11 Release date: 2017-04-12 Last modified: 2017-11-22 Method: X-RAY DIFFRACTION (3.796 Å) Cite: Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
4IQX	Mutant P44S P169S M296I of Foot-and-mouth disease Virus RNA-dependent RNA polymerase Descriptor: 3D polymerase, RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3'), RNA (5'-R(*GP*GP*CP*CP*C)-3') Authors: Ferrer-Orta, C, Verdaguer, N, Agudo, R, Perez-Luque, R. Deposit date: 2013-01-14 Release date: 2013-02-06 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.5 Å) Cite: A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape. Plos Pathog., 6, 2010
3KMS	G62S mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA trigonal structure Descriptor: 3D polymerase, MAGNESIUM ION, RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3'), ... Authors: Ferrer-Orta, C, Verdaguer, N, Perez-Luque, R. Deposit date: 2009-11-11 Release date: 2010-07-07 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin J.Virol., 84, 2010
3KNA	M296I mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA Descriptor: 3D polymerase, MAGNESIUM ION, RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3'), ... Authors: Ferrer-Orta, C, Verdaguer, N, Perez-Luque, R. Deposit date: 2009-11-12 Release date: 2010-07-07 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin J.Virol., 84, 2010
3KOA	M296I mutant of foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA and GTP Descriptor: 3D polymerase, DIPHOSPHATE, MAGNESIUM ION, ... Authors: Ferrer-Orta, C, Verdaguer, N, Perez-Luque, R. Deposit date: 2009-11-13 Release date: 2010-07-07 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin J.Virol., 84, 2010
8QJ7	Cryo-EM structure of human DNA polymerase alpha-primase in pre-initiation stage 1 Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ... Authors: Yin, Z, Pellegrini, L. Deposit date: 2023-09-12 Release date: 2024-02-21 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.07 Å) Cite: CryoEM insights into RNA primer synthesis by the human primosome. Febs J., 291, 2024

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