PDB: 533 resultsInfo pagesStatus searchChemie searchBIRD

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1QKW	Alpha-spectrin Src Homology 3 domain, N47G mutant in the distal loop. Descriptor: ALPHA II SPECTRIN, GLYCEROL, SULFATE ION Authors: Vega, M.C, Martinez, J, Serrano, L. Deposit date: 1999-08-16 Release date: 2000-08-18 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Thermodynamic and structural characterization of Asn and Ala residues in the disallowed II' region of the Ramachandran plot. Protein Sci., 9, 2000
1QLY	NMR Study of the SH3 Domain From Bruton's Tyrosine Kinase, 20 Structures Descriptor: TYROSINE-PROTEIN KINASE BTK Authors: Tzeng, S.R, Lou, Y.C, Pai, M.T, Chen, C, Chen, S.H, Cheng, J.Y. Deposit date: 1999-09-20 Release date: 1999-12-14 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Solution Structure of the Human Btk SH3 Domain Complexed with a Proline-Rich Peptide from P120Cbl J.Biomol.NMR, 16, 2000
1E6H	A-SPECTRIN SH3 DOMAIN A11V, M25I, V44I, V58L MUTANTS Descriptor: SPECTRIN ALPHA CHAIN Authors: Vega, M.C, Serrano, L. Deposit date: 2000-08-17 Release date: 2002-05-23 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design Nat.Struct.Biol., 9, 2002
1GCQ	CRYSTAL STRUCTURE OF VAV AND GRB2 SH3 DOMAINS Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, VAV PROTO-ONCOGENE Authors: Nishida, M, Nagata, K, Hachimori, Y, Ogura, K, Inagaki, F. Deposit date: 2000-08-08 Release date: 2001-08-08 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.68 Å) Cite: Novel recognition mode between Vav and Grb2 SH3 domains. EMBO J., 20, 2001
1GFD	SOLUTION STRUCTURE AND LIGAND-BINDING SITE OF THE C-TERMINAL SH3 DOMAIN OF GRB2 Descriptor: GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 Authors: Kohda, D, Terasawa, H, Hatanaka, H, Inagaki, F. Deposit date: 1994-06-13 Release date: 1994-08-31 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2. Structure, 2, 1994
1GFC	SOLUTION STRUCTURE AND LIGAND-BINDING SITE OF THE C-TERMINAL SH3 DOMAIN OF GRB2 Descriptor: GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 Authors: Kohda, D, Terasawa, H, Hatanaka, H, Inagaki, F. Deposit date: 1994-06-13 Release date: 1994-08-31 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2. Structure, 2, 1994
1CKA	STRUCTURAL BASIS FOR THE SPECIFIC INTERACTION OF LYSINE-CONTAINING PROLINE-RICH PEPTIDES WITH THE N-TERMINAL SH3 DOMAIN OF C-CRK Descriptor: C-CRK N-TERMINAL SH3 DOMAIN, C3G PEPTIDE (PRO-PRO-PRO-ALA-LEU-PRO-PRO-LYS-LYS-ARG) Authors: Wu, X, Kuriyan, J. Deposit date: 1995-01-24 Release date: 1995-05-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk. Structure, 3, 1995
1CKB	STRUCTURAL BASIS FOR THE SPECIFIC INTERACTION OF LYSINE-CONTAINING PROLINE-RICH PEPTIDES WITH THE N-TERMINAL SH3 DOMAIN OF C-CRK Descriptor: C-CRK N-TERMINAL SH3 DOMAIN, SOS PEPTIDE (PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG-ARG) Authors: Wu, X, Kuriyan, J. Deposit date: 1995-01-24 Release date: 1995-05-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural basis for the specific interaction of lysine-containing proline-rich peptides with the N-terminal SH3 domain of c-Crk. Structure, 3, 1995
1GBQ	SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, MINIMIZED AVERAGE STRUCTURE Descriptor: GRB2, SOS-1 Authors: Wittekind, M, Mapelli, C, Lee, V, Goldfarb, V, Friedrichs, M.S, Meyers, C.A, Mueller, L. Deposit date: 1996-12-23 Release date: 1997-09-04 Last modified: 2022-02-23 Method: SOLUTION NMR Cite: Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts. J.Mol.Biol., 267, 1997
1G2B	ALPHA-SPECTRIN SRC HOMOLOGY 3 DOMAIN, CIRCULAR PERMUTANT, CUT AT N47-D48 Descriptor: SPECTRIN ALPHA CHAIN, SULFATE ION Authors: Berisio, R, Viguera, A.R, Serrano, L, Wilmanns, M. Deposit date: 2000-10-18 Release date: 2000-11-01 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.12 Å) Cite: Atomic resolution structure of a mutant of the spectrin SH3 domain. Acta Crystallogr.,Sect.D, 57, 2001
1GBR	ORIENTATION OF PEPTIDE FRAGMENTS FROM SOS PROTEINS BOUND TO THE N-TERMINAL SH3 DOMAIN OF GRB2 DETERMINED BY NMR SPECTROSCOPY Descriptor: GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, SOS-A PEPTIDE Authors: Wittekind, M, Mapelli, C, Farmer, B.T, Suen, K.-L, Goldfarb, V, Tsao, J, Lavoie, T, Barbacid, M, Meyers, C.A, Mueller, L. Deposit date: 1994-08-12 Release date: 1995-01-26 Last modified: 2024-05-22 Method: SOLUTION NMR Cite: Orientation of peptide fragments from Sos proteins bound to the N-terminal SH3 domain of Grb2 determined by NMR spectroscopy. Biochemistry, 33, 1994
1GL5	NMR structure of the SH3 domain from the Tec protein tyrosine kinase Descriptor: TYROSINE-PROTEIN KINASE TEC Authors: Mulhern, T.D, Pursglove, S.E, Booker, G.W. Deposit date: 2001-08-28 Release date: 2001-11-28 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: The solution structure and intramolecular associations of the Tec kinase SRC homology 3 domain. J. Biol. Chem., 277, 2002
1FYN	PHOSPHOTRANSFERASE Descriptor: 3BP-2, PHOSPHOTRANSFERASE FYN Authors: Musacchio, A, Saraste, M, Wilmanns, M. Deposit date: 1995-05-17 Release date: 1996-11-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.3 Å) Cite: High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides. Nat.Struct.Biol., 1, 1994
1GCP	CRYSTAL STRUCTURE OF VAV SH3 DOMAIN Descriptor: VAV PROTO-ONCOGENE Authors: Nishida, M, Nagata, K, Hachimori, Y, Ogura, K, Inagaki, F. Deposit date: 2000-08-08 Release date: 2001-08-08 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Novel recognition mode between Vav and Grb2 SH3 domains. EMBO J., 20, 2001
1HD3	A-SPECTRIN SH3 DOMAIN F52Y MUTANT Descriptor: GLYCEROL, SPECTRIN ALPHA CHAIN, SULFATE ION Authors: Vega, M.C, Viguera, A.R, Serrano, L. Deposit date: 2000-11-06 Release date: 2001-11-01 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Unspecific Hydrophobic Stabilization of Folding Transition States Proc.Natl.Acad.Sci.USA, 99, 2002
1H3H	Structural Basis for Specific Recognition of an RxxK-containing SLP-76 peptide by the Gads C-terminal SH3 domain Descriptor: GRB2-RELATED ADAPTOR PROTEIN 2, LYMPHOCYTE CYTOSOLIC PROTEIN 2 Authors: Liu, Q, Berry, D, Nash, P, Pawson, T, McGlade, C.J, Li, S.S. Deposit date: 2002-09-03 Release date: 2003-03-06 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structural Basis for Specific Binding of the Gads SH3 Domain to an Rxxk Motif-Containing Slp-76 Peptide: A Novel Mode of Peptide Recognition Mol.Cell, 11, 2003
1E6G	A-SPECTRIN SH3 DOMAIN A11V, V23L, M25I, V53I, V58L MUTANT Descriptor: SPECTRIN ALPHA CHAIN, SULFATE ION Authors: Vega, M.C, Serrano, L. Deposit date: 2000-08-15 Release date: 2002-05-23 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design Nat.Struct.Biol., 9, 2002
1E7O	A-SPECTRIN SH3 DOMAIN A11V, V23L, M25V, V44I, V58L MUTATIONS Descriptor: GLYCEROL, SPECTRIN ALPHA CHAIN Authors: Vega, M.C, Serrano, L. Deposit date: 2000-08-31 Release date: 2003-05-21 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (3.2 Å) Cite: A Thermodynamic and Kinetic Analysis of the Folding Pathway of an SH3 Domain Entropically Stabilised by a Redesigned Hydrophobic Core J.Mol.Biol., 328, 2003
1H8K	A-SPECTRIN SH3 DOMAIN A11V, V23L, M25V, V53I, V58L MUTANT Descriptor: SPECTRIN ALPHA CHAIN Authors: Vega, M.C, Serrano, L. Deposit date: 2001-02-09 Release date: 2002-05-23 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design Nat.Struct.Biol., 9, 2002
4HXJ	Crystal structure of SH3:RGT complex Descriptor: C-terminal 3-mer peptide from Integrin beta-3, Proto-oncogene tyrosine-protein kinase Src Authors: Xiao, R, Meng, G. Deposit date: 2012-11-11 Release date: 2012-11-28 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural framework of c-Src activation by integrin beta 3 Blood, 121, 2013
4HVW	Crystal structure of the T98E c-Src-SH3 domain mutant in complex with the high affinity peptide VSL12 Descriptor: ACETYL GROUP, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, ... Authors: Camara-Artigas, A. Deposit date: 2012-11-07 Release date: 2013-05-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (0.98 Å) Cite: Atomic resolution structures of the c-Src SH3 domain in complex with two high-affinity peptides from classes I and II. Acta Crystallogr.,Sect.D, 69, 2013
4HVV	Crystal structure of the T98E c-Src-SH3 domain mutant in complex with the high affinity peptide APP12 Descriptor: Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, SYNTHETIC PEPTIDE Acetyl-APPLPPRNRP Authors: Camara-Artigas, A. Deposit date: 2012-11-07 Release date: 2013-05-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.1 Å) Cite: Atomic resolution structures of the c-Src SH3 domain in complex with two high-affinity peptides from classes I and II. Acta Crystallogr.,Sect.D, 69, 2013
4J9E	Crystal structure of the N114A mutant of the Abl-SH3 domain complexed with the high affinity peptide P17 Descriptor: P17, SULFATE ION, Tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A. Deposit date: 2013-02-16 Release date: 2014-01-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Crystal structure of the N114A mutant of the Abl-SH3 domain complexed with the high affinity peptide P17 To be Published
4J9C	Crystal structure of the Abl-SH3 domain H59Q-N96T mutant complexed with the designed high-affinity peptide ligand P17 Descriptor: DI(HYDROXYETHYL)ETHER, P17, TRIETHYLENE GLYCOL, ... Authors: Camara-Artigas, A. Deposit date: 2013-02-16 Release date: 2014-01-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.051 Å) Cite: Crystal structure of the Abl-SH3 domain H59Q-N96T mutant complexed with the designed high-affinity peptide ligand P17 To be Published
4J9G	Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P7 at pH7 Descriptor: GLYCEROL, P7, SULFATE ION, ... Authors: Camara-Artigas, A. Deposit date: 2013-02-16 Release date: 2014-01-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P7 To be Published

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